Variant report

Variant	esv33843
Chromosome Location	chr11:59908131-59945334
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:395)
CpG islands
(count:122)
Chromatin interactive
region (count:12)
LncRNA
region (count:3)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:395 , 50 per page) page: 1 2 3 4 5 6 7 8

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ATF2	chr11:59943277-59943643	GM12878	blood:	n/a	n/a
2	BATF	chr11:59933083-59933319	GM12878	blood:	n/a	chr11:59933195-59933206 chr11:59933200-59933210 chr11:59933196-59933206
3	BATF	chr11:59932241-59932528	GM12878	blood:	n/a	n/a
4	BATF	chr11:59935878-59936155	GM12878	blood:	n/a	chr11:59936013-59936024
5	BATF	chr11:59933032-59933326	GM12878	blood:	n/a	chr11:59933195-59933206 chr11:59933200-59933210 chr11:59933196-59933206
6	BATF	chr11:59943289-59943622	GM12878	blood:	n/a	n/a
7	BCL11A	chr11:59943312-59943754	GM12878	blood:	n/a	n/a
8	BCL11A	chr11:59943260-59943782	GM12878	blood:	n/a	n/a
9	BCL11A	chr11:59917814-59918037	GM12878	blood:	n/a	n/a
10	BHLHE40	chr11:59943291-59943766	GM12878	blood:	n/a	n/a
11	BRCA1	chr11:59936747-59937294	Hela-S3	cervix:	n/a	n/a
12	CBX3	chr11:59936709-59937256	HCT-116	colon:	n/a	n/a
13	CBX3	chr11:59932030-59932403	K562	blood:	n/a	n/a
14	CBX3	chr11:59936750-59937326	K562	blood:	n/a	n/a
15	CBX3	chr11:59936668-59937147	HCT-116	colon:	n/a	n/a
16	CBX3	chr11:59936531-59937429	K562	blood:	n/a	n/a
17	CEBPB	chr11:59926111-59926443	Hela-S3	cervix:	n/a	n/a
18	CEBPB	chr11:59925423-59925665	HepG2	liver:	n/a	n/a
19	CEBPB	chr11:59925415-59925615	K562	blood:	n/a	n/a
20	CEBPB	chr11:59936727-59937366	Hela-S3	cervix:	n/a	n/a
21	CEBPB	chr11:59936786-59937096	K562	blood:	n/a	n/a
22	CEBPB	chr11:59927378-59927703	Hela-S3	cervix:	n/a	n/a
23	CEBPB	chr11:59936903-59937114	H1-hESC	embryonic stem cell:	n/a	n/a
24	CEBPB	chr11:59940902-59940936	K562	blood:	n/a	n/a
25	CEBPB	chr11:59943241-59943836	GM12878	blood:	n/a	chr11:59943749-59943762
26	CEBPB	chr11:59943009-59943267	Hela-S3	cervix:	n/a	n/a
27	CHD1	chr11:59936960-59937014	GM12878	blood:	n/a	n/a
28	CHD2	chr11:59936702-59937270	Hela-S3	cervix:	n/a	n/a
29	CHD2	chr11:59936342-59936360	HepG2	liver:	n/a	n/a
30	CTCF	chr11:59937115-59937280	A549	lung:	n/a	chr11:59937221-59937242
31	CTCF	chr11:59937120-59937270	NHEK	skin:	n/a	chr11:59937221-59937242
32	CTCF	chr11:59937180-59937330	AG09319	gingival:	n/a	chr11:59937221-59937242
33	CTCF	chr11:59929297-59929477	K562	blood:	n/a	n/a
34	CTCF	chr11:59937200-59937350	K562	blood:	n/a	chr11:59937221-59937242
35	CTCF	chr11:59937160-59937310	HBMEC	blood vessel:	n/a	chr11:59937221-59937242
36	CTCF	chr11:59937040-59937190	GM12801	blood:	n/a	n/a
37	CTCF	chr11:59937120-59937270	HUVEC	blood vessel:	n/a	chr11:59937221-59937242
38	CTCF	chr11:59937220-59937370	HFF-Myc	foreskin:	n/a	chr11:59937221-59937242
39	CTCF	chr11:59937180-59937330	GM12874	blood:	n/a	chr11:59937221-59937242
40	CTCF	chr11:59929369-59929509	HUVEC	blood vessel:	n/a	n/a
41	CTCF	chr11:59937160-59937310	Caco-2	colon:	n/a	chr11:59937221-59937242
42	CTCF	chr11:59937120-59937270	MCF-7	breast:	n/a	chr11:59937221-59937242
43	CTCF	chr11:59937113-59937346	K562	blood:	n/a	chr11:59937221-59937242
44	CTCF	chr11:59937120-59937270	GM12865	blood:	n/a	chr11:59937221-59937242
45	CTCF	chr11:59937090-59937336	SK-N-SH_RA	brain:	n/a	chr11:59937221-59937242
46	CTCF	chr11:59937220-59937370	GM12878	blood:	n/a	chr11:59937221-59937242
47	CTCF	chr11:59937180-59937330	GM12870	blood:	n/a	chr11:59937221-59937242
48	CTCF	chr11:59937080-59937230	WERI-Rb-1	eye:	n/a	n/a
49	CTCF	chr11:59929424-59929469	K562	blood:	n/a	n/a
50	CTCF	chr11:59937099-59937368	H1-hESC	embryonic stem cell:	n/a	chr11:59937221-59937242

(count:122 , 50 per page) page: 1 2 3

No.	Chromosome Location	Cell Line	Cell type	Cell Stage
1	chr11:59940485-59940535	SK-N-SH	brain:	n/a
2	chr11:59940485-59940535	BE2_C	brain:	n/a
3	chr11:59942032-59942082	HEK293	kidney:	embryo
4	chr11:59942032-59942082	NHDF-neo	bronchial:	n/a
5	chr11:59940485-59940535	RPTEC	kidney:	n/a
6	chr11:59942032-59942082	HepG2	liver:	n/a
7	chr11:59942032-59942082	HCM	heart:	n/a
8	chr11:59940485-59940535	GM19239	blood:	n/a
9	chr11:59940485-59940535	NH-A	brain:	n/a
10	chr11:59940485-59940535	PFSK-1	brain:	n/a
11	chr11:59940485-59940535	GM12891	blood:	n/a
12	chr11:59940485-59940535	AoSMC	blood vessel:	n/a
13	chr11:59942032-59942082	ovcar-3	ovarian:	n/a
14	chr11:59940485-59940535	ECC-1	luminal epithelium:	n/a
15	chr11:59942032-59942082	RPTEC	kidney:	n/a
16	chr11:59940485-59940535	ProgFib	skin:	n/a
17	chr11:59940485-59940535	CMK	blood:	n/a
18	chr11:59942032-59942082	NT2-D1	testis:	n/a
19	chr11:59942032-59942082	ECC-1	luminal epithelium:	n/a
20	chr11:59940485-59940535	T-47D	breast:	n/a
21	chr11:59940485-59940535	A549	lung:	n/a
22	chr11:59940485-59940535	HIPEpiC	eye:	n/a
23	chr11:59940485-59940535	ovcar-3	ovarian:	n/a
24	chr11:59942032-59942082	H1-hESC	embryonic stem cell:	embryo
25	chr11:59942032-59942082	GM12891	blood:	n/a
26	chr11:59942032-59942082	SK-N-SH	brain:	n/a
27	chr11:59940485-59940535	NB4	blood:	n/a
28	chr11:59940485-59940535	IMR90	lung:	fetal
29	chr11:59940485-59940535	U87	brain:	n/a
30	chr11:59942032-59942082	HRCEpiC	kidney:	n/a
31	chr11:59942032-59942082	BJ	skin:	n/a
32	chr11:59940485-59940535	HEK293	kidney:	embryo
33	chr11:59940485-59940535	AG04450	lung:	fetal
34	chr11:59940485-59940535	BJ	skin:	n/a
35	chr11:59942032-59942082	AG04450	lung:	fetal
36	chr11:59942032-59942082	HAEpiC	amniotic membrane:	n/a
37	chr11:59942032-59942082	CMK	blood:	n/a
38	chr11:59942032-59942082	HCF	heart:	n/a
39	chr11:59942032-59942082	HNPCEpiC	eye:	n/a
40	chr11:59940485-59940535	H1-hESC	embryonic stem cell:	embryo
41	chr11:59940485-59940535	HUVEC	blood vessel:	n/a
42	chr11:59940485-59940535	SK-N-MC	brain:	n/a
43	chr11:59940485-59940535	GM12892	blood:	n/a
44	chr11:59942032-59942082	NH-A	brain:	n/a
45	chr11:59940485-59940535	NHDF-neo	bronchial:	n/a
46	chr11:59942032-59942082	A549	lung:	n/a
47	chr11:59942032-59942082	ProgFib	skin:	n/a
48	chr11:59942032-59942082	SK-N-MC	brain:	n/a
49	chr11:59942032-59942082	AG09319	gingival:	n/a
50	chr11:59940485-59940535	MCF10A-Er-Src	breast:	n/a

(count:12 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr11:59803708..59805688-chr11:59908661..59910786,2	K562	blood:
2	chr11:59926973..59929170-chr11:59934444..59937067,2	K562	blood:
3	chr11:59936023..59937006-chr11:59960779..59961684,2	MCF-7	breast:
4	chr11:59915996..59916912-chr11:59960707..59961353,2	K562	blood:
5	chr11:59926779..59928855-chr11:59938111..59940679,2	K562	blood:
6	chr11:59905623..59908151-chr11:59911648..59914024,2	K562	blood:
7	chr11:59905623..59908151-chr11:59911648..59914024,2	K562	blood:
8	chr11:59909863..59911734-chr11:59915341..59917142,2	K562	blood:
9	chr11:59899268..59901225-chr11:59929250..59931810,2	K562	blood:
10	chr11:59929729..59931318-chr11:59936371..59938548,3	K562	blood:
11	chr11:59929729..59931318-chr11:59936371..59938548,3	K562	blood:
12	chr11:59909863..59911734-chr11:59915341..59917142,2	K562	blood:

(count:3 , 50 per page) page: 1

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-MS4A6A-1	chr11:59927752-59927855	ENSG00000254952
2	lnc-MS4A6A-1	chr11:59928198-59928295	ENSG00000254952
3	lnc-MS4A6A-1	chr11:59927160-59927342	ENSG00000254952

No data

Variant related genes	Relation type
ENSG00000254952	TF binding region
ENSG00000254952	CpG island
ENSG00000254952	chromatin interactions

Extended variants
information (count: 1030 )
Associated
traits (count: 61 )

Variant overlapped rSNPs/rCNVs (count:1030 , 50 per page) page: 1 2 3 4 5 6 7 ... 21

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs564519634	chr11:59910409-59910410	Enhancers	n/a	n/a	Overlapped CNVs	n/a
2	rs537149537	chr11:59910465-59910466	Enhancers	n/a	n/a	Overlapped CNVs	n/a
3	rs140199944	chr11:59910490-59910491	Enhancers	n/a	n/a	Overlapped CNVs	n/a
4	rs546759479	chr11:59910497-59910498	Enhancers	n/a	n/a	Overlapped CNVs	n/a
5	rs187781829	chr11:59910498-59910499	Enhancers	n/a	n/a	Overlapped CNVs	n/a
6	rs529329755	chr11:59910516-59910517	Enhancers	n/a	n/a	Overlapped CNVs	n/a
7	rs556710999	chr11:59910519-59910520	Enhancers	n/a	n/a	Overlapped CNVs	n/a
8	rs550949731	chr11:59910651-59910652	Enhancers	n/a	n/a	Overlapped CNVs	n/a
9	rs144240725	chr11:59910685-59910686	Enhancers	n/a	n/a	Overlapped CNVs	n/a
10	rs569186505	chr11:59910763-59910764	Enhancers	n/a	n/a	Overlapped CNVs	n/a
11	rs542491096	chr11:59910783-59910784	Enhancers	n/a	n/a	Overlapped CNVs	n/a
12	rs551600406	chr11:59910860-59910861	Enhancers	n/a	n/a	Overlapped CNVs	n/a
13	rs566527752	chr11:59910894-59910895	Enhancers	n/a	n/a	Overlapped CNVs	n/a
14	rs533923206	chr11:59910980-59910981	Enhancers	n/a	n/a	Overlapped CNVs	n/a
15	rs191565133	chr11:59911018-59911019	Enhancers	n/a	n/a	Overlapped CNVs	n/a
16	rs34980963	chr11:59911055-59911056	Enhancers	n/a	n/a	Overlapped CNVs	n/a
17	rs115190138	chr11:59911082-59911083	Enhancers	n/a	n/a	Overlapped CNVs	n/a
18	rs537456355	chr11:59911104-59911105	Enhancers	n/a	n/a	Overlapped CNVs	n/a
19	rs555729756	chr11:59911106-59911107	Enhancers	n/a	n/a	Overlapped CNVs	n/a
20	rs34815499	chr11:59911138-59911139	Enhancers	n/a	n/a	Overlapped CNVs	n/a
21	rs575938204	chr11:59911145-59911146	Enhancers	n/a	n/a	Overlapped CNVs	n/a
22	rs546156695	chr11:59911157-59911158	Enhancers	n/a	n/a	Overlapped CNVs	n/a
23	rs564733329	chr11:59911159-59911160	Enhancers	n/a	n/a	Overlapped CNVs	n/a
24	rs569046	chr11:59911161-59911162	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
25	rs112178748	chr11:59911213-59911214	Enhancers	n/a	n/a	Overlapped CNVs	n/a
26	rs573104407	chr11:59911332-59911333	Enhancers	n/a	n/a	Overlapped CNVs	n/a
27	rs145501869	chr11:59911344-59911345	Enhancers	n/a	n/a	Overlapped CNVs	n/a
28	rs545004741	chr11:59911369-59911370	Enhancers	n/a	n/a	Overlapped CNVs	n/a
29	rs562169124	chr11:59911373-59911374	Enhancers	n/a	n/a	Overlapped CNVs	n/a
30	rs564688601	chr11:59911483-59911484	Enhancers	n/a	n/a	Overlapped CNVs	n/a
31	rs148425938	chr11:59911499-59911500	Enhancers	n/a	n/a	Overlapped CNVs	n/a
32	rs370741226	chr11:59911507-59911508	Enhancers	n/a	n/a	Overlapped CNVs	n/a
33	rs958682	chr11:59911509-59911510	Enhancers	n/a	n/a	Overlapped CNVs	n/a
34	rs369124534	chr11:59911516-59911517	Enhancers	n/a	n/a	Overlapped CNVs	n/a
35	rs375255261	chr11:59911530-59911531	Enhancers	n/a	n/a	Overlapped CNVs	n/a
36	rs533285720	chr11:59911575-59911576	Enhancers	n/a	n/a	Overlapped CNVs	n/a
37	rs551371899	chr11:59911586-59911587	Enhancers	n/a	n/a	Overlapped CNVs	n/a
38	rs11230159	chr11:59911587-59911588	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
39	rs377280117	chr11:59911652-59911653	Enhancers	n/a	n/a	Overlapped CNVs	n/a
40	rs533750722	chr11:59911723-59911724	Enhancers	n/a	n/a	Overlapped CNVs	n/a
41	rs183852324	chr11:59911734-59911735	Enhancers	n/a	n/a	Overlapped CNVs	n/a
42	rs567061862	chr11:59911746-59911747	Enhancers	n/a	n/a	Overlapped CNVs	n/a
43	rs530501829	chr11:59911772-59911773	Enhancers	n/a	n/a	Overlapped CNVs	n/a
44	rs544232137	chr11:59911791-59911792	Enhancers	n/a	n/a	Overlapped CNVs	n/a
45	rs79522941	chr11:59911814-59911815	Enhancers	n/a	n/a	Overlapped CNVs	n/a
46	rs563311051	chr11:59911874-59911875	Enhancers	n/a	n/a	Overlapped CNVs	n/a
47	rs571138360	chr11:59911884-59911885	Enhancers	n/a	n/a	Overlapped CNVs	n/a
48	rs544981687	chr11:59911896-59911897	Enhancers	n/a	n/a	Overlapped CNVs	n/a
49	rs13377336	chr11:59911915-59911916	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
50	rs558191777	chr11:59911979-59911980	Enhancers	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:61)

Disease	PMID	Source
Medulloblastoma	21979893	CNVD
Gastric cancer	17908304	CNVD
Multiple myeloma	20724749	CNVD
Wilms tumour	21544195	CNVD
Autism	22495311	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Non-small cell lung cancer	21385341	CNVD
Intellectual disability	22102821	CNVD
Glioblastoma multiforme	21138945	CNVD
Esophageal cancer	21851588	CNVD
Acute myeloid leukemia	20729466	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Acute lymphoblastic leukemia	20067559	CNVD
Cancer	21637783	CNVD
Acute myeloid leukemia	16864856	CNVD
Chronic lymphocytic leukemia	21795749	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Neuroblastoma	21484798	CNVD
Ewing''s sarcoma	21437220	CNVD
Oral cancer	21386901	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	20837533	CNVD
Breast cancer	21264507	CNVD
Cervical cancer	21063398	CNVD
Glioblastoma multiforme	19960244	CNVD
Liposarcoma	21253554	CNVD
Neuroblastoma	18923524	CNVD
Neuroblastoma	18664255	CNVD
Monoclonal gammopathy of undetermined significance	17077331	CNVD
Multiple myeloma	17077331	CNVD
Neuroblastoma	17533364	CNVD
Breast cancer	21364760	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
small cell lung cancer	20016488	CNVD
Lung cancer	18438408	CNVD
Colorectal cancer	16272173	CNVD
Esophageal squamous carcinoma	18350619	CNVD
Pituitary adenoma	18645599	CNVD
Basal cell lymphoma	16317097	CNVD
Diffuse large b-cell lymphoma	16317097	CNVD
Prostate cancer	18632612	CNVD
Myelofibrosis	22110671	CNVD
Glioblastoma multiforme	21080181	CNVD
Smith-Lemli-Opitz syndrome	21572526	CNVD
Multiple myeloma	16461302	CNVD
Cancer	16751803	CNVD
Seminomas	18059402	CNVD
Autism	22495309	CNVD
Autism	20808228	CNVD
Acute lymphoblastic leukemia	21339820	CNVD
Splenic marginal zone lymphoma	21957467	CNVD
Lung adenocarcinoma	17086460	CNVD
Metanephric adenoma	20802469	CNVD
Chordoma	21602918	CNVD
Melanoma	18172304	CNVD
Gastric cancer	16891809	CNVD
Lung cancer	17086460	CNVD
Chordoma	18071362	CNVD
Pancreatic cancer	17952125	CNVD
Breast cancer	22522925	CNVD
Non-syndromic sensorineural hearing loss	22037309	CNVD

Chromatin state (count:104 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:59910400-59912800	Enhancers	Dnd41	blood
2	chr11:59912400-59913400	Enhancers	Primary monocytes fromperipheralblood	blood
3	chr11:59912600-59913200	Enhancers	Monocytes-CD14+_RO01746	blood
4	chr11:59923000-59923200	Enhancers	Monocytes-CD14+_RO01746	blood
5	chr11:59923000-59923800	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
6	chr11:59923000-59924000	Enhancers	Primary monocytes fromperipheralblood	blood
7	chr11:59923200-59923400	Enhancers	Primary neutrophils fromperipheralblood	blood
8	chr11:59923200-59923400	Enhancers	HUVEC	blood vessel
9	chr11:59923200-59924000	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Male	--
10	chr11:59923200-59924000	Flanking Active TSS	Monocytes-CD14+_RO01746	blood
11	chr11:59923400-59923800	Active TSS	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
12	chr11:59923400-59923800	Flanking Active TSS	Primary neutrophils fromperipheralblood	blood
13	chr11:59923400-59923800	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
14	chr11:59923400-59923800	Enhancers	HMEC	breast
15	chr11:59923400-59923800	Flanking Active TSS	HUVEC	blood vessel
16	chr11:59923400-59924000	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
17	chr11:59923800-59924000	Enhancers	Primary neutrophils fromperipheralblood	blood
18	chr11:59923800-59924000	Enhancers	HUVEC	blood vessel
19	chr11:59924000-59924800	Weak transcription	Monocytes-CD14+_RO01746	blood
20	chr11:59924000-59926400	Weak transcription	HUVEC	blood vessel
21	chr11:59924000-59930800	Weak transcription	Primary monocytes fromperipheralblood	blood
22	chr11:59924000-59932800	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
23	chr11:59924800-59929800	Strong transcription	Monocytes-CD14+_RO01746	blood
24	chr11:59926400-59930000	Enhancers	HUVEC	blood vessel
25	chr11:59929800-59930600	Weak transcription	Monocytes-CD14+_RO01746	blood
26	chr11:59930000-59932400	Weak transcription	HUVEC	blood vessel
27	chr11:59930600-59933400	Strong transcription	Monocytes-CD14+_RO01746	blood
28	chr11:59930800-59931800	Strong transcription	Primary monocytes fromperipheralblood	blood
29	chr11:59931800-59935600	Weak transcription	Primary monocytes fromperipheralblood	blood
30	chr11:59932400-59933800	Enhancers	HMEC	breast
31	chr11:59932400-59935200	Enhancers	HUVEC	blood vessel
32	chr11:59932800-59933800	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
33	chr11:59933000-59934800	Enhancers	Fetal Adrenal Gland	Adrenal Gland
34	chr11:59933000-59935800	Weak transcription	Primary neutrophils fromperipheralblood	blood
35	chr11:59933400-59935400	Weak transcription	Monocytes-CD14+_RO01746	blood
36	chr11:59933800-59936200	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
37	chr11:59933800-59936200	Weak transcription	HMEC	breast
38	chr11:59934400-59934600	Enhancers	Primary B cells from cord blood	blood
39	chr11:59934600-59935400	Weak transcription	Primary B cells from cord blood	blood
40	chr11:59935200-59935600	Weak transcription	HUVEC	blood vessel
41	chr11:59935400-59935800	ZNF genes & repeats	Primary B cells from cord blood	blood
42	chr11:59935400-59936200	Strong transcription	Monocytes-CD14+_RO01746	blood
43	chr11:59935600-59936400	Active TSS	Colonic Mucosa	Colon
44	chr11:59935600-59937200	Strong transcription	Primary monocytes fromperipheralblood	blood
45	chr11:59935600-59937400	ZNF genes & repeats	ES-UCSF4 Cell Line	embryonic stem cell
46	chr11:59935600-59940400	Enhancers	HUVEC	blood vessel
47	chr11:59935800-59937000	ZNF genes & repeats	Spleen	Spleen
48	chr11:59935800-59947200	Strong transcription	Primary neutrophils fromperipheralblood	blood
49	chr11:59936000-59936800	ZNF genes & repeats	HUES64 Cell Line	embryonic stem cell
50	chr11:59936200-59936600	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell

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