Variant report

Variant	rs12908421
Chromosome Location	chr15:76881794-76881795
allele	G/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr15:76877558..76879609-chr15:76881319..76882907,2	K562	blood:

Variant related genes	Relation type
ENSG00000266449	Chromatin interaction

Extended variants
information (count: 133 )
Associated
traits (count: 4 )

rSNPs within LD-proxies of this variant (count:94)

rs_ID	r²[population]
rs10444858	0.81[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs11072603	0.89[ASN][1000 genomes]
rs1116535	0.85[ASN][1000 genomes]
rs1117367	0.89[ASN][1000 genomes]
rs1125932	0.89[AMR][1000 genomes];0.91[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12148452	0.80[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs12148877	0.85[AMR][1000 genomes];0.89[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs12437627	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12438077	0.82[AFR][1000 genomes];0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12438186	0.84[AMR][1000 genomes];0.88[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs12438540	0.88[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs12440151	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs12441247	0.82[AMR][1000 genomes];0.85[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12441433	0.82[ASN][1000 genomes]
rs12441550	0.82[AFR][1000 genomes];0.91[AMR][1000 genomes];0.93[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12443137	0.88[ASN][1000 genomes]
rs12594541	0.83[ASN][1000 genomes]
rs12594577	0.85[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12595313	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs12898430	0.89[ASN][1000 genomes]
rs12900494	0.84[AMR][1000 genomes];0.89[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs12902174	0.82[AFR][1000 genomes];0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs12902414	0.80[AFR][1000 genomes];0.80[AMR][1000 genomes]
rs12902452	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs12903553	0.81[EUR][1000 genomes]
rs12911987	0.81[ASN][1000 genomes]
rs1471780	0.85[ASN][1000 genomes]
rs1838048	0.89[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs1867197	0.80[AFR][1000 genomes];0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs1874944	0.82[AFR][1000 genomes];0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs1946650	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2056544	0.83[ASN][1000 genomes]
rs2120107	0.89[ASN][1000 genomes]
rs2120108	0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs2304920	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs2404733	0.81[ASN][1000 genomes]
rs2404736	0.92[AMR][1000 genomes];0.95[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs2404737	0.94[AMR][1000 genomes];0.95[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs2404740	0.88[ASN][1000 genomes]
rs2404741	0.86[ASN][1000 genomes]
rs2896954	0.88[ASN][1000 genomes]
rs34060246	0.88[ASN][1000 genomes]
rs34272342	0.85[ASN][1000 genomes]
rs34287706	0.88[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs34478400	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs34639578	0.80[ASN][1000 genomes]
rs34707035	0.88[ASN][1000 genomes]
rs34924128	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs35077207	0.89[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs35138393	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs35195096	0.89[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs35395069	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs35498563	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs35566346	0.89[AMR][1000 genomes];0.89[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs36070630	0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs3816266	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs4525456	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs4886496	0.94[ASN][1000 genomes]
rs4886813	0.89[AMR][1000 genomes];0.92[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs4886817	0.91[AFR][1000 genomes];0.94[AMR][1000 genomes];0.95[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs4886818	0.88[ASN][1000 genomes]
rs4886822	0.84[EUR][1000 genomes]
rs4886824	0.86[ASN][1000 genomes]
rs4886825	0.88[ASN][1000 genomes]
rs55676827	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs56193230	0.89[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs56351018	0.82[AMR][1000 genomes];0.85[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs57178708	0.80[AFR][1000 genomes];0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs58361452	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs58511211	0.81[AMR][1000 genomes];0.84[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs58973160	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs59088060	0.90[AMR][1000 genomes];0.95[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs60912217	0.86[ASN][1000 genomes]
rs6495206	0.89[ASN][1000 genomes]
rs66754747	0.89[AMR][1000 genomes];0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs67010831	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs67204011	0.80[AFR][1000 genomes];0.89[AMR][1000 genomes];0.94[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs67570291	0.88[ASN][1000 genomes]
rs67920045	0.81[AMR][1000 genomes];0.81[EUR][1000 genomes]
rs71405216	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs71405222	0.83[ASN][1000 genomes]
rs71405223	0.88[ASN][1000 genomes]
rs7163397	0.89[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs7169394	0.85[AMR][1000 genomes];0.89[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs7174953	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs72738889	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs7342603	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs7350777	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs7495566	0.82[ASN][1000 genomes]
rs8024476	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs8036703	0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs8037005	0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs8043474	0.81[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs9646213	0.80[AMR][1000 genomes];0.82[EUR][1000 genomes];0.90[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:39 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv542438	chr15:76697056-76892157	Weak transcription Strong transcription ZNF genes & repeats Enhancers Flanking Active TSS Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	3 gene(s)	inside rSNPs	diseases
2	nsv542439	chr15:76762161-77196336	Enhancers Weak transcription Strong transcription ZNF genes & repeats Flanking Active TSS Active TSS Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	9 gene(s)	inside rSNPs	diseases
3	esv3440794	chr15:76764595-77571114	Weak transcription Enhancers Strong transcription Active TSS Flanking Active TSS Genic enhancers ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	25 gene(s)	inside rSNPs	diseases
4	nsv904400	chr15:76772062-77085283	Strong transcription Weak transcription Genic enhancers ZNF genes & repeats Enhancers Active TSS Flanking Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
5	nsv1053924	chr15:76803849-77089079	Enhancers Strong transcription Flanking Active TSS ZNF genes & repeats Weak transcription Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
6	nsv471254	chr15:76811390-76978139	Enhancers Strong transcription Weak transcription ZNF genes & repeats Flanking Active TSS Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA	2 gene(s)	inside rSNPs	diseases
7	nsv570021	chr15:76813920-76978139	Enhancers Weak transcription Flanking Active TSS ZNF genes & repeats Strong transcription Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA	2 gene(s)	inside rSNPs	diseases
8	nsv570022	chr15:76816015-76978139	ZNF genes & repeats Strong transcription Weak transcription Enhancers Genic enhancers Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	2 gene(s)	inside rSNPs	diseases
9	nsv904401	chr15:76816015-77085283	Strong transcription Enhancers ZNF genes & repeats Weak transcription Flanking Active TSS Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
10	nsv1042514	chr15:76838221-76906382	Weak transcription ZNF genes & repeats Enhancers Active TSS Strong transcription Genic enhancers Flanking Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
11	nsv1042089	chr15:76855098-77016127	Weak transcription Enhancers ZNF genes & repeats Genic enhancers Strong transcription Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
12	nsv1038233	chr15:76855205-76895763	Enhancers ZNF genes & repeats Weak transcription Strong transcription Flanking Active TSS Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
13	nsv1037282	chr15:76859309-76895763	Active TSS Flanking Active TSS ZNF genes & repeats Weak transcription Enhancers Strong transcription Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
14	nsv1044453	chr15:76860198-76895763	Enhancers Weak transcription Strong transcription Flanking Active TSS Active TSS ZNF genes & repeats Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
15	nsv1620	chr15:76862152-76914288	Enhancers Weak transcription Active TSS Strong transcription ZNF genes & repeats Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
16	nsv904402	chr15:76863023-76930805	Strong transcription Weak transcription Enhancers ZNF genes & repeats Active TSS Genic enhancers Flanking Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
17	esv2830013	chr15:76863023-77176158	Weak transcription ZNF genes & repeats Strong transcription Enhancers Flanking Active TSS Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
18	nsv1042623	chr15:76863437-76999030	Weak transcription Enhancers Strong transcription ZNF genes & repeats Flanking Active TSS Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
19	nsv1039269	chr15:76863437-77057021	Weak transcription Strong transcription Enhancers ZNF genes & repeats Flanking Active TSS Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
20	nsv1048577	chr15:76868215-76895763	Enhancers Weak transcription ZNF genes & repeats Active TSS Strong transcription Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
21	nsv1051037	chr15:76868215-76902257	Enhancers Weak transcription Genic enhancers ZNF genes & repeats Flanking Active TSS Strong transcription Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
22	nsv1038521	chr15:76869789-76895763	Enhancers Weak transcription Strong transcription Active TSS Flanking Active TSS ZNF genes & repeats Genic enhancers	TF binding region Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
23	nsv1042304	chr15:76869929-76895763	Enhancers Weak transcription Strong transcription ZNF genes & repeats Flanking Active TSS Genic enhancers Active TSS	TF binding region Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
24	esv3584695	chr15:76869929-76895775	ZNF genes & repeats Enhancers Strong transcription Weak transcription Flanking Active TSS Active TSS Genic enhancers	TF binding region Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
25	nsv1042883	chr15:76869929-76902458	Weak transcription Enhancers Active TSS ZNF genes & repeats Strong transcription Genic enhancers Flanking Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
26	nsv904403	chr15:76869929-76951040	Weak transcription Strong transcription Enhancers Flanking Active TSS ZNF genes & repeats Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
27	nsv904404	chr15:76869929-77033934	Strong transcription ZNF genes & repeats Weak transcription Enhancers Flanking Active TSS Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	3 gene(s)	inside rSNPs	diseases
28	nsv904405	chr15:76869929-77047915	Weak transcription Enhancers Strong transcription ZNF genes & repeats Genic enhancers Active TSS Flanking Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
29	nsv904406	chr15:76869929-77085283	Weak transcription Strong transcription ZNF genes & repeats Enhancers Genic enhancers Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
30	nsv904407	chr15:76869929-77121196	Weak transcription Strong transcription Active TSS ZNF genes & repeats Enhancers Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA	4 gene(s)	inside rSNPs	diseases
31	nsv1043878	chr15:76878362-76895763	ZNF genes & repeats Weak transcription Enhancers Genic enhancers Strong transcription Active TSS Flanking Active TSS	TF binding region Chromatin interactive region miRNA	1 gene(s)	inside rSNPs	diseases
32	nsv1040711	chr15:76878362-76902257	Strong transcription Weak transcription Enhancers ZNF genes & repeats Genic enhancers Active TSS Flanking Active TSS	TF binding region CpG island Chromatin interactive region miRNA	1 gene(s)	inside rSNPs	diseases
33	nsv1040450	chr15:76878362-76902458	Weak transcription ZNF genes & repeats Enhancers Flanking Active TSS Strong transcription Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region miRNA	1 gene(s)	inside rSNPs	diseases
34	nsv1053005	chr15:76878362-76903184	ZNF genes & repeats Genic enhancers Weak transcription Enhancers Strong transcription Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region miRNA	1 gene(s)	inside rSNPs	diseases
35	esv2760392	chr15:76878362-76903196	Weak transcription ZNF genes & repeats Enhancers Strong transcription Active TSS Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region miRNA	1 gene(s)	inside rSNPs	diseases
36	nsv1048948	chr15:76878362-76910031	Weak transcription ZNF genes & repeats Strong transcription Enhancers Genic enhancers Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region miRNA	1 gene(s)	inside rSNPs	diseases
37	nsv1052133	chr15:76878362-76962756	Weak transcription Enhancers ZNF genes & repeats Strong transcription Active TSS Genic enhancers Flanking Active TSS	TF binding region CpG island Chromatin interactive region miRNA	2 gene(s)	inside rSNPs	diseases
38	nsv510668	chr15:76879852-76901937	Enhancers Weak transcription ZNF genes & repeats Strong transcription Genic enhancers Active TSS Flanking Active TSS	Chromatin interactive region	1 gene(s)	inside rSNPs	diseases
39	nsv116	chr15:76880628-76914288	Weak transcription Enhancers Strong transcription Flanking Active TSS ZNF genes & repeats Genic enhancers Active TSS	TF binding region CpG island Chromatin interactive region	2 gene(s)	inside rSNPs	diseases

mRNA abundance (count:4)

SNP	Gene	Cis/trans	Tissue	Source
rs12908421	SCAPER	Cis_1M	lymphoblastoid	RTeQTL
rs12908421	SCAPER	cis	Thyroid	GTEx
rs12908421	SCAPER	cis	Artery Tibial	GTEx
rs12908421	SCAPER	cis	lung	GTEx

Chromatin state (count:41 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:76871000-76883600	Weak transcription	Ovary	ovary
2	chr15:76876000-76883600	Weak transcription	Aorta	Aorta
3	chr15:76877400-76883400	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
4	chr15:76878200-76884200	Weak transcription	Right Ventricle	heart
5	chr15:76878800-76884800	Weak transcription	Primary T cells from cord blood	blood
6	chr15:76879400-76883400	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
7	chr15:76879600-76883400	Weak transcription	Monocytes-CD14+_RO01746	blood
8	chr15:76879800-76881800	Weak transcription	Liver	Liver
9	chr15:76879800-76881800	Weak transcription	Duodenum Smooth Muscle	Duodenum
10	chr15:76879800-76885600	Weak transcription	Pancreas	Pancrea
11	chr15:76880200-76883200	Weak transcription	Primary hematopoietic stem cells short term culture	blood
12	chr15:76880400-76883200	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
13	chr15:76880400-76883200	Weak transcription	Skeletal Muscle Male	skeletal muscle
14	chr15:76880400-76883600	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
15	chr15:76880600-76883200	Weak transcription	Fetal Muscle Trunk	muscle
16	chr15:76880600-76883400	Weak transcription	Fetal Muscle Leg	muscle
17	chr15:76881200-76881800	Enhancers	Fetal Intestine Small	intestine
18	chr15:76881200-76882000	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
19	chr15:76881200-76882000	ZNF genes & repeats	Lung	lung
20	chr15:76881200-76882400	ZNF genes & repeats	Primary hematopoietic stem cells G-CSF-mobilized Male	--
21	chr15:76881200-76882400	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
22	chr15:76881200-76882400	Enhancers	Fetal Intestine Large	intestine
23	chr15:76881200-76882400	Strong transcription	Fetal Stomach	stomach
24	chr15:76881200-76882600	Strong transcription	Thymus	Thymus
25	chr15:76881400-76881800	Active TSS	Colonic Mucosa	Colon
26	chr15:76881400-76882000	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
27	chr15:76881400-76882200	Enhancers	Sigmoid Colon	Sigmoid Colon
28	chr15:76881400-76882400	Strong transcription	Stomach Smooth Muscle	stomach
29	chr15:76881400-76882400	Enhancers	NHEK	skin
30	chr15:76881600-76881800	Enhancers	Duodenum Mucosa	Duodenum
31	chr15:76881600-76882000	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
32	chr15:76881600-76882000	ZNF genes & repeats	Pancreatic Islets	Pancreatic Islet
33	chr15:76881600-76882000	Enhancers	Left Ventricle	heart
34	chr15:76881600-76882000	Flanking Active TSS	Rectal Mucosa Donor 31	rectum
35	chr15:76881600-76882000	Enhancers	HepG2	liver
36	chr15:76881600-76882200	Strong transcription	Primary mononuclear cells fromperipheralblood	Blood
37	chr15:76881600-76882400	Strong transcription	Primary B cells from cord blood	blood
38	chr15:76881600-76882400	Strong transcription	Primary B cells from peripheral blood	blood
39	chr15:76881600-76882400	Flanking Active TSS	Rectal Mucosa Donor 29	rectum
40	chr15:76881600-76882600	ZNF genes & repeats	Esophagus	oesophagus
41	chr15:76881600-76883000	Strong transcription	Breast Myoepithelial Primary Cells	Breast

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