Variant report

Variant	rs2456066
Chromosome Location	chr15:76587371-76587372
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:0)
CpG islands
(count:0)
Chromatin interactive
region (count:13)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

No data

(count:13 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr15:76585221..76587431-chr15:76590533..76592803,2	K562	blood:
2	chr15:76585050..76587534-chr15:76621476..76624273,2	MCF-7	breast:
3	chr15:76586392..76589038-chr15:76597420..76599518,2	K562	blood:
4	chr15:76575946..76578111-chr15:76585028..76587734,2	MCF-7	breast:
5	chr15:76586585..76588473-chr15:76607510..76609209,2	MCF-7	breast:
6	chr15:76582923..76594852-chr15:76601949..76606997,18	MCF-7	breast:
7	chr15:76586485..76588241-chr15:76606261..76609045,2	K562	blood:
8	chr15:76576792..76578437-chr15:76586446..76588190,2	MCF-7	breast:
9	chr15:76586734..76589503-chr15:76636258..76638931,2	K562	blood:
10	chr15:76570590..76572904-chr15:76586063..76587618,2	K562	blood:
11	chr15:76584744..76587703-chr15:77223601..77225703,2	K562	blood:
12	chr15:76584959..76587924-chr15:76602984..76605259,2	K562	blood:
13	chr15:76584135..76596152-chr15:76600630..76606670,15	MCF-7	breast:

No data

Variant related genes	Relation type
ENSG00000140374	Chromatin interaction
ENSG00000117906	Chromatin interaction

Extended variants
information (count: 66 )
Associated
traits (count: 2 )

rSNPs within LD-proxies of this variant (count:66)

rs_ID	r²[population]
rs11858964	0.84[EUR][1000 genomes]
rs157777	0.87[CEU][hapmap]
rs157778	0.87[CEU][hapmap]
rs1801591	0.87[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.83[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs1810348	1.00[CEU][hapmap];0.86[EUR][1000 genomes]
rs1914816	1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[ASN][1000 genomes]
rs2078437	0.87[CEU][hapmap]
rs2291449	0.87[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.83[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2456027	1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[ASN][1000 genomes]
rs2456033	0.87[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2456040	0.84[AMR][1000 genomes];0.88[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2456042	0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.88[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2456047	1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[AMR][1000 genomes];0.82[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2456054	0.85[YRI][hapmap];0.84[AMR][1000 genomes]
rs2456063	1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2456067	0.97[AFR][1000 genomes];0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs2456070	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.89[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2456072	1.00[CHB][hapmap];1.00[JPT][hapmap];0.88[YRI][hapmap];0.89[ASN][1000 genomes]
rs2456074	0.92[AFR][1000 genomes];0.95[AMR][1000 genomes];1.00[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2456075	0.89[ASN][1000 genomes]
rs2456078	0.89[ASN][1000 genomes]
rs2460146	1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[ASN][1000 genomes]
rs2460151	1.00[CHB][hapmap];1.00[JPT][hapmap];0.86[YRI][hapmap];0.89[ASN][1000 genomes]
rs2460153	1.00[CEU][hapmap];1.00[CHB][hapmap];0.80[YRI][hapmap];0.89[AMR][1000 genomes];0.84[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2460155	1.00[CHB][hapmap];0.83[YRI][hapmap]
rs2460158	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2460161	0.87[CEU][hapmap]
rs2469211	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];0.89[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2469212	1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2469214	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.99[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2469215	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[YRI][hapmap];0.99[AFR][1000 genomes];0.89[AMR][1000 genomes];0.97[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2469216	0.97[AFR][1000 genomes];0.84[AMR][1000 genomes];0.97[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2469533	0.92[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2469538	0.95[AFR][1000 genomes];0.95[AMR][1000 genomes];0.97[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2469539	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.92[AFR][1000 genomes];0.95[AMR][1000 genomes];0.97[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2469544	0.80[YRI][hapmap];0.81[ASN][1000 genomes]
rs2469552	0.96[AFR][1000 genomes];0.89[AMR][1000 genomes];0.95[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2469554	0.87[CEU][hapmap]
rs2469564	0.88[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.89[AMR][1000 genomes];0.84[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2469568	1.00[CHB][hapmap];0.95[YRI][hapmap];0.89[AMR][1000 genomes]
rs2469573	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.88[YRI][hapmap];1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs283796	0.87[CEU][hapmap]
rs284898	0.87[CEU][hapmap]
rs284902	0.87[CEU][hapmap]
rs284903	0.87[CEU][hapmap]
rs284904	0.87[CEU][hapmap]
rs284905	0.87[CEU][hapmap]
rs284907	0.87[CEU][hapmap]
rs2938691	0.89[ASN][1000 genomes]
rs2956875	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];0.89[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2957037	1.00[CHB][hapmap];1.00[JPT][hapmap];0.83[YRI][hapmap];0.89[ASN][1000 genomes]
rs2957607	0.87[CEU][hapmap]
rs2957613	0.87[CEU][hapmap]
rs2959846	0.87[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs387321	0.87[CEU][hapmap]
rs4489970	0.86[EUR][1000 genomes]
rs4886490	1.00[CEU][hapmap];0.86[EUR][1000 genomes]
rs4886491	0.87[CEU][hapmap]
rs4886492	0.87[CEU][hapmap]
rs6495200	0.97[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs7180257	0.84[EUR][1000 genomes]
rs8031378	0.87[CEU][hapmap]
rs8031672	0.82[CEU][hapmap]
rs8042255	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.97[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs874223	0.86[EUR][1000 genomes]
rs874224	1.00[CEU][hapmap];1.00[YRI][hapmap];0.87[AFR][1000 genomes];0.84[AMR][1000 genomes];0.86[EUR][1000 genomes]

mRNA abundance (count:2)

SNP	Gene	Cis/trans	Tissue	Source
rs2456066	ISL2	Cis_1M	lymphoblastoid	RTeQTL
rs2456066	ISL2	cis	Whole Blood	GTEx

Chromatin state (count:81 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:76556800-76594600	Weak transcription	Esophagus	oesophagus
2	chr15:76558000-76603000	Weak transcription	Aorta	Aorta
3	chr15:76561000-76587600	Weak transcription	H1 Cell Line	embryonic stem cell
4	chr15:76562000-76591600	Weak transcription	Small Intestine	intestine
5	chr15:76563200-76590800	Weak transcription	Pancreatic Islets	Pancreatic Islet
6	chr15:76569800-76591600	Weak transcription	Spleen	Spleen
7	chr15:76573200-76592200	Weak transcription	Fetal Kidney	kidney
8	chr15:76573200-76593200	Weak transcription	Right Ventricle	heart
9	chr15:76574800-76590600	Weak transcription	Ovary	ovary
10	chr15:76574800-76591600	Weak transcription	Gastric	stomach
11	chr15:76574800-76591600	Weak transcription	Lung	lung
12	chr15:76574800-76601400	Weak transcription	Pancreas	Pancrea
13	chr15:76574800-76602000	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
14	chr15:76576200-76602800	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
15	chr15:76579200-76591600	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
16	chr15:76579200-76602000	Weak transcription	Thymus	Thymus
17	chr15:76579400-76591000	Weak transcription	Duodenum Smooth Muscle	Duodenum
18	chr15:76579400-76592600	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
19	chr15:76579400-76592800	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
20	chr15:76579600-76592000	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
21	chr15:76579600-76592600	Weak transcription	Primary T killer memory cells from peripheral blood	blood
22	chr15:76579600-76592600	Weak transcription	Dnd41	blood
23	chr15:76579600-76602000	Weak transcription	HUES6 Cell Line	embryonic stem cell
24	chr15:76579800-76593000	Weak transcription	Primary T helper cells fromperipheralblood	blood
25	chr15:76580200-76596000	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
26	chr15:76580400-76590400	Weak transcription	HUES64 Cell Line	embryonic stem cell
27	chr15:76580400-76591400	Weak transcription	Primary neutrophils fromperipheralblood	blood
28	chr15:76580400-76591600	Weak transcription	Sigmoid Colon	Sigmoid Colon
29	chr15:76580400-76593200	Weak transcription	Skeletal Muscle Female	skeletal muscle
30	chr15:76580600-76600400	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
31	chr15:76581000-76588200	Weak transcription	Left Ventricle	heart
32	chr15:76582200-76591600	Weak transcription	GM12878-XiMat	blood
33	chr15:76582400-76594400	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
34	chr15:76583400-76590600	Weak transcription	HepG2	liver
35	chr15:76583400-76592000	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
36	chr15:76583400-76592600	Weak transcription	Primary B cells from peripheral blood	blood
37	chr15:76583600-76589600	Weak transcription	Fetal Muscle Leg	muscle
38	chr15:76583600-76590600	Weak transcription	NHEK	skin
39	chr15:76583600-76591600	Weak transcription	Duodenum Mucosa	Duodenum
40	chr15:76583600-76602000	Weak transcription	Breast Myoepithelial Primary Cells	Breast
41	chr15:76583800-76591400	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
42	chr15:76583800-76602000	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
43	chr15:76584000-76590400	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
44	chr15:76584000-76601400	Weak transcription	Placenta	Placenta
45	chr15:76584200-76590800	Weak transcription	Fetal Intestine Small	intestine
46	chr15:76584600-76589000	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
47	chr15:76584600-76590400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
48	chr15:76584600-76591600	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
49	chr15:76584600-76602400	Weak transcription	Primary B cells from cord blood	blood
50	chr15:76584800-76590600	Weak transcription	Liver	Liver

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