Variant report

Variant	rs2766581
Chromosome Location	chr6:35750299-35750300
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	NR3C1	chr6:35750253-35750449	A549	lung:	n/a	n/a
2	ESR1	chr6:35750108-35750638	T-47D	breast:	n/a	n/a
3	GATA3	chr6:35750071-35750684	MCF-7	breast:	n/a	chr6:35750653-35750663
4	NR2F2	chr6:35750074-35750617	MCF-7	breast:	n/a	n/a
5	FOS	chr6:35750290-35750491	MCF10A-Er-Src	breast:	n/a	n/a
6	ESR1	chr6:35750180-35750592	T-47D	breast:	n/a	n/a
7	STAT3	chr6:35750265-35750574	MCF10A-Er-Src	breast:	n/a	n/a
8	NR3C1	chr6:35750226-35750617	A549	lung:	n/a	n/a
9	SIN3AK20	chr6:35749961-35750706	MCF-7	breast:	n/a	n/a
10	ESR1	chr6:35750071-35750638	T-47D	breast:	n/a	n/a
11	TFAP2C	chr6:35750228-35750593	Hela-S3	cervix:	n/a	chr6:35750420-35750435
12	TCF12	chr6:35750162-35750719	MCF-7	breast:	n/a	n/a
13	HDAC2	chr6:35750095-35750635	MCF-7	breast:	n/a	n/a
14	MYC	chr6:35750255-35750507	MCF10A-Er-Src	breast:	n/a	n/a
15	ESR1	chr6:35750096-35750610	T-47D	breast:	n/a	n/a
16	FOS	chr6:35750283-35750501	MCF10A-Er-Src	breast:	n/a	n/a
17	TCF12	chr6:35749857-35750738	MCF-7	breast:	n/a	n/a
18	ESR1	chr6:35750168-35750532	T-47D	breast:	n/a	n/a
19	NR3C1	chr6:35750236-35750489	A549	lung:	n/a	n/a
20	STAT3	chr6:35750188-35750534	MCF10A-Er-Src	breast:	n/a	n/a
21	STAT3	chr6:35750259-35750459	MCF10A-Er-Src	breast:	n/a	n/a
22	ESR1	chr6:35750097-35750605	T-47D	breast:	n/a	n/a
23	EP300	chr6:35750209-35750581	T-47D	breast:	n/a	n/a
24	FOXA1	chr6:35750247-35750516	T-47D	breast:	n/a	n/a
25	FOS	chr6:35750280-35750482	MCF10A-Er-Src	breast:	n/a	n/a
26	NR3C1	chr6:35750244-35750478	ECC-1	luminal epithelium:	n/a	n/a
27	ELF1	chr6:35750069-35750560	MCF-7	breast:	n/a	n/a
28	STAT3	chr6:35750248-35750495	MCF10A-Er-Src	breast:	n/a	n/a
29	ELF1	chr6:35750122-35750650	MCF-7	breast:	n/a	n/a

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr6:35748849..35751627-chr6:35754286..35755906,2	K562	blood:
2	chr6:35748849..35750883-chr6:35754286..35755862,2	K562	blood:

Variant related genes	Relation type
CLPSL1	TF binding region
ENSG00000204140	Chromatin interaction

Extended variants
information (count: 25 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:6)

rs_ID	r²[population]
rs2478468	0.87[AFR][1000 genomes];0.99[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs2766577	0.82[EUR][1000 genomes]
rs2766578	0.82[EUR][1000 genomes]
rs2766579	0.93[AFR][1000 genomes];0.90[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs2766580	0.96[AFR][1000 genomes];0.87[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs9394318	0.83[EUR][1000 genomes];0.91[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:19 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv2758048	chr6:35463741-35806504	Genic enhancers Weak transcription Active TSS Bivalent Enhancer Enhancers Strong transcription Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	52 gene(s)	inside rSNPs	diseases
2	esv2759420	chr6:35463741-35806504	Flanking Bivalent TSS/Enh Weak transcription Flanking Active TSS Enhancers Active TSS Bivalent Enhancer Genic enhancers Strong transcription Transcr. at gene 5' and 3' Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	52 gene(s)	inside rSNPs	diseases
3	nsv602924	chr6:35505311-35750299	Weak transcription Flanking Active TSS Strong transcription Enhancers Active TSS Genic enhancers Transcr. at gene 5' and 3' Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
4	esv3430300	chr6:35549151-35959004	Flanking Active TSS Strong transcription Enhancers Active TSS Weak transcription ZNF genes & repeats Flanking Bivalent TSS/Enh Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	52 gene(s)	inside rSNPs	diseases
5	nsv821646	chr6:35604428-35802594	Enhancers Weak transcription Active TSS Strong transcription Bivalent Enhancer Genic enhancers Flanking Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
6	nsv885802	chr6:35621781-35787417	Active TSS Enhancers Flanking Active TSS Weak transcription Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Strong transcription Bivalent Enhancer ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
7	nsv885803	chr6:35621781-35805133	Enhancers Flanking Active TSS Active TSS Bivalent Enhancer Weak transcription Bivalent/Poised TSS Strong transcription Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
8	nsv885804	chr6:35621781-35809776	Active TSS Enhancers Bivalent Enhancer Weak transcription Flanking Active TSS Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
9	nsv428143	chr6:35637083-35806504	Enhancers Flanking Bivalent TSS/Enh Weak transcription Bivalent Enhancer Active TSS Strong transcription Flanking Active TSS Transcr. at gene 5' and 3' Genic enhancers Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	32 gene(s)	inside rSNPs	diseases
10	nsv885805	chr6:35685955-35779879	Enhancers Weak transcription Flanking Active TSS Bivalent/Poised TSS Active TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3' ZNF genes & repeats Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases
11	nsv525686	chr6:35734051-35750299	Enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Weak transcription Flanking Active TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	5 gene(s)	inside rSNPs	diseases
12	nsv7891	chr6:35744190-35772539	Weak transcription Flanking Bivalent TSS/Enh Bivalent/Poised TSS Flanking Active TSS Transcr. at gene 5' and 3' Bivalent Enhancer Active TSS Enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
13	esv1798998	chr6:35744609-35765951	Active TSS Weak transcription Bivalent Enhancer Enhancers Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
14	esv33535	chr6:35747703-35771315	Weak transcription Bivalent Enhancer Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region	7 gene(s)	inside rSNPs	diseases
15	nsv819076	chr6:35748900-35766425	Bivalent Enhancer Weak transcription Enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS Active TSS Flanking Active TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region	7 gene(s)	inside rSNPs	diseases
16	esv1793061	chr6:35749079-35765951	Flanking Bivalent TSS/Enh Bivalent Enhancer Flanking Active TSS ZNF genes & repeats Weak transcription Enhancers Transcr. at gene 5' and 3' Active TSS Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region	7 gene(s)	inside rSNPs	diseases
17	esv1806871	chr6:35749079-35771286	Enhancers Bivalent/Poised TSS Bivalent Enhancer Flanking Active TSS Weak transcription Flanking Bivalent TSS/Enh Active TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region	7 gene(s)	inside rSNPs	diseases
18	esv1816210	chr6:35749079-35771286	Weak transcription Bivalent Enhancer Enhancers Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Active TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region	7 gene(s)	inside rSNPs	diseases
19	esv1845214	chr6:35749079-35771286	Bivalent Enhancer Enhancers Weak transcription ZNF genes & repeats Flanking Active TSS Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region	7 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:7 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr6:35746400-35755400	Weak transcription	Pancreas	Pancrea
2	chr6:35750000-35750600	Enhancers	Breast Myoepithelial Primary Cells	Breast
3	chr6:35750000-35750600	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
4	chr6:35750000-35750600	Enhancers	HMEC	breast
5	chr6:35750000-35750800	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
6	chr6:35750200-35750400	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
7	chr6:35750200-35750600	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin

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