Variant report

Variant	rs7461756
Chromosome Location	chr8:126138197-126138198
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr8:126138185..126141108-chr8:126441359..126446173,6	MCF-7	breast:
2	chr8:126126335..126143313-chr8:126439680..126445836,35	MCF-7	breast:
3	chr8:126136833..126139565-chr8:126560076..126562610,2	MCF-7	breast:
4	chr8:126137562..126138829-chr8:126443663..126444827,4	MCF-7	breast:

Variant related genes	Relation type
ENSG00000173334	Chromatin interaction

Extended variants
information (count: 42 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:38)

rs_ID	r²[population]
rs10094316	0.83[CHB][hapmap];0.81[CHD][hapmap]
rs10100556	0.83[CHB][hapmap]
rs10112218	0.80[CHB][hapmap]
rs10481077	1.00[MEX][hapmap]
rs10481078	1.00[MEX][hapmap]
rs10956233	0.80[GIH][hapmap]
rs13249982	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.86[AFR][1000 genomes];0.80[AMR][1000 genomes];0.95[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs13253942	0.90[CEU][hapmap]
rs13254947	0.90[CEU][hapmap]
rs13259062	0.90[CEU][hapmap]
rs13266794	0.94[AFR][1000 genomes];0.93[AMR][1000 genomes];0.98[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs13277490	0.90[CEU][hapmap]
rs16900457	1.00[MEX][hapmap]
rs16900461	1.00[MEX][hapmap]
rs17310558	0.90[CEU][hapmap]
rs17401283	0.90[CEU][hapmap]
rs2384882	0.89[CEU][hapmap]
rs2891630	0.84[CHD][hapmap]
rs35114839	0.89[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs35779726	0.95[AFR][1000 genomes];0.83[AMR][1000 genomes];0.94[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs3923300	0.90[CEU][hapmap]
rs4360308	0.90[CEU][hapmap]
rs4601329	0.90[CEU][hapmap]
rs4870935	0.83[CHB][hapmap]
rs5007394	0.83[CHB][hapmap]
rs56326134	0.80[AFR][1000 genomes]
rs58805022	0.82[AFR][1000 genomes];0.86[AMR][1000 genomes]
rs6470338	0.83[CHB][hapmap];0.84[CHD][hapmap]
rs6470339	0.83[CHB][hapmap];0.84[CHD][hapmap]
rs6470341	0.86[AFR][1000 genomes];0.83[AMR][1000 genomes];0.95[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs6992545	1.00[MEX][hapmap]
rs6995096	0.83[CHB][hapmap]
rs7002224	0.92[YRI][hapmap]
rs7014707	0.85[LWK][hapmap];0.87[MKK][hapmap];0.92[YRI][hapmap]
rs7813225	0.83[CHB][hapmap]
rs7827336	0.84[LWK][hapmap];1.00[MEX][hapmap];0.87[MKK][hapmap];0.92[YRI][hapmap]
rs7837996	1.00[MEX][hapmap]
rs868227	0.81[CEU][hapmap]

Variant overlapped rSNPs/rCNVs (count:4 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv891434	chr8:125630655-126324432	Strong transcription Enhancers Weak transcription Active TSS Genic enhancers Flanking Active TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	80 gene(s)	inside rSNPs	diseases
2	nsv949614	chr8:126063646-126376699	Weak transcription Enhancers Strong transcription Flanking Active TSS ZNF genes & repeats Active TSS Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases
3	nsv917158	chr8:126101990-126255266	Enhancers Weak transcription Flanking Active TSS Strong transcription Active TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region	19 gene(s)	inside rSNPs	diseases
4	nsv1022954	chr8:126117811-126180331	Enhancers Weak transcription Strong transcription ZNF genes & repeats Active TSS Flanking Active TSS Genic enhancers	TF binding region CpG island Chromatin interactive region	6 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs7461756	TNFSF11	trans	lymphoblastoid	seeQTL

Chromatin state (count:110 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr8:126105200-126156400	Weak transcription	Fetal Brain Male	brain
2	chr8:126117400-126138400	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
3	chr8:126117400-126140400	Weak transcription	Right Ventricle	heart
4	chr8:126117600-126157400	Weak transcription	Fetal Brain Female	brain
5	chr8:126117800-126160400	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
6	chr8:126118000-126191800	Weak transcription	Thymus	Thymus
7	chr8:126118400-126153600	Weak transcription	Placenta Amnion	Placenta Amnion
8	chr8:126120600-126156400	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
9	chr8:126121000-126142800	Weak transcription	Primary hematopoietic stem cells	blood
10	chr8:126131600-126142800	Weak transcription	Brain Anterior Caudate	brain
11	chr8:126133200-126140400	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
12	chr8:126133200-126140400	Weak transcription	Brain Angular Gyrus	brain
13	chr8:126133200-126140400	Weak transcription	Ovary	ovary
14	chr8:126133200-126140800	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
15	chr8:126133200-126140800	Weak transcription	Psoas Muscle	Psoas
16	chr8:126133200-126142200	Weak transcription	Sigmoid Colon	Sigmoid Colon
17	chr8:126133200-126142800	Weak transcription	Brain Inferior Temporal Lobe	brain
18	chr8:126133400-126140400	Weak transcription	Skeletal Muscle Female	skeletal muscle
19	chr8:126133400-126140600	Weak transcription	Duodenum Smooth Muscle	Duodenum
20	chr8:126133400-126143000	Weak transcription	iPS-18 Cell Line	embryonic stem cell
21	chr8:126133800-126143000	Weak transcription	HUES48 Cell Line	embryonic stem cell
22	chr8:126133800-126146200	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
23	chr8:126134000-126140600	Weak transcription	Skeletal Muscle Male	skeletal muscle
24	chr8:126134400-126140800	Weak transcription	Small Intestine	intestine
25	chr8:126136400-126138200	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
26	chr8:126136600-126138200	ZNF genes & repeats	Primary monocytes fromperipheralblood	blood
27	chr8:126136800-126138200	ZNF genes & repeats	H1 Derived Mesenchymal Stem Cells	ES cell derived
28	chr8:126136800-126138200	ZNF genes & repeats	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
29	chr8:126136800-126138200	ZNF genes & repeats	IMR90 fetal lung fibroblasts Cell Line	lung
30	chr8:126136800-126138200	ZNF genes & repeats	Primary B cells from cord blood	blood
31	chr8:126136800-126138200	ZNF genes & repeats	Primary B cells from peripheral blood	blood
32	chr8:126136800-126138200	ZNF genes & repeats	Primary T regulatory cells fromperipheralblood	blood
33	chr8:126136800-126138400	ZNF genes & repeats	Primary Natural Killer cells fromperipheralblood	blood
34	chr8:126136800-126139600	Strong transcription	Foreskin Melanocyte Primary Cells skin03	Skin
35	chr8:126137000-126138200	ZNF genes & repeats	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
36	chr8:126137000-126138200	Enhancers	Rectal Mucosa Donor 31	rectum
37	chr8:126137200-126138200	ZNF genes & repeats	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
38	chr8:126137200-126138200	ZNF genes & repeats	Fetal Muscle Leg	muscle
39	chr8:126137200-126138200	ZNF genes & repeats	GM12878-XiMat	blood
40	chr8:126137200-126138200	ZNF genes & repeats	NHDF-Ad	bronchial
41	chr8:126137200-126138200	ZNF genes & repeats	NHEK	skin
42	chr8:126137200-126138400	ZNF genes & repeats	A549	lung
43	chr8:126137200-126139600	ZNF genes & repeats	HSMMtube	muscle
44	chr8:126137400-126138200	ZNF genes & repeats	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
45	chr8:126137400-126138200	ZNF genes & repeats	Primary neutrophils fromperipheralblood	blood
46	chr8:126137400-126138200	Strong transcription	Primary T cells from cord blood	blood
47	chr8:126137400-126138200	ZNF genes & repeats	Primary hematopoietic stem cells short term culture	blood
48	chr8:126137400-126138200	ZNF genes & repeats	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
49	chr8:126137400-126138200	ZNF genes & repeats	Muscle Satellite Cultured Cells	--
50	chr8:126137400-126138200	Strong transcription	Foreskin Fibroblast Primary Cells skin02	Skin

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links