Variant report

Variant	rs878373
Chromosome Location	chr4:120237484-120237485
allele	A/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr4:120234842..120237819-chr4:120239424..120241485,2	K562	blood:

Extended variants
information (count: 207 )
Associated
traits (count: 11 )

rSNPs within LD-proxies of this variant (count:202)

rs_ID	r²[population]
rs10003567	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10005237	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10005973	0.82[ASN][1000 genomes]
rs10006877	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs10008386	0.86[AMR][1000 genomes]
rs10008392	0.86[AMR][1000 genomes]
rs10010696	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs10012456	0.87[AMR][1000 genomes];0.86[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs10014719	0.84[AMR][1000 genomes]
rs10016944	0.83[AMR][1000 genomes]
rs10017271	0.86[AMR][1000 genomes]
rs10017371	0.89[AMR][1000 genomes];0.83[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs10017543	0.84[AMR][1000 genomes]
rs10020034	0.86[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs10020141	0.80[AMR][1000 genomes]
rs1002152	0.87[AMR][1000 genomes];0.86[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs10022262	0.84[AMR][1000 genomes];0.82[EUR][1000 genomes]
rs10023569	0.80[AMR][1000 genomes]
rs10024844	0.86[AMR][1000 genomes]
rs10024933	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs10025054	0.86[AMR][1000 genomes]
rs10026436	0.89[AMR][1000 genomes];0.82[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs10028423	0.80[AMR][1000 genomes]
rs10028669	0.87[AMR][1000 genomes];0.83[ASN][1000 genomes]
rs10029750	0.86[AMR][1000 genomes];0.85[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs10031718	0.82[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs1011054	0.87[AMR][1000 genomes];0.88[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs10212714	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs10212719	0.89[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs10212775	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10213158	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs10213267	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10213342	0.82[AMR][1000 genomes];0.84[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs1022145	0.99[AFR][1000 genomes];1.00[AMR][1000 genomes];0.98[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs10518300	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs10518331	0.80[AMR][1000 genomes]
rs10857068	0.83[AMR][1000 genomes]
rs11098496	0.86[AMR][1000 genomes];0.85[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs11098499	0.85[AFR][1000 genomes];0.90[AMR][1000 genomes];0.87[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs11098501	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs11098502	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs11098513	0.86[AMR][1000 genomes]
rs11098514	0.86[AMR][1000 genomes]
rs11722183	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs11722872	0.92[AFR][1000 genomes];0.99[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs11723581	0.84[AMR][1000 genomes]
rs11724409	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs11724758	0.83[ASN][1000 genomes]
rs11726229	0.83[AFR][1000 genomes];0.90[AMR][1000 genomes];0.88[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs11728730	0.80[AMR][1000 genomes];0.86[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs11729897	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs11729991	0.89[AMR][1000 genomes];0.83[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs11732087	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs11732686	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs11734519	0.84[AMR][1000 genomes];0.84[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs11931312	0.86[AMR][1000 genomes];0.80[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs11944880	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs12498994	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12499598	0.83[AFR][1000 genomes];0.90[AMR][1000 genomes];0.84[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs12501610	0.86[AMR][1000 genomes];0.84[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs12504149	0.87[AMR][1000 genomes]
rs12505469	0.95[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs12506148	0.84[AMR][1000 genomes]
rs12506395	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs12506610	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs12507565	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12508173	0.87[AMR][1000 genomes]
rs12509621	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12510269	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs12511640	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12512118	0.86[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs12512154	0.84[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs12512517	0.87[AMR][1000 genomes];0.84[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs12513083	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12711071	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs13104396	0.89[AMR][1000 genomes];0.82[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs13108589	0.84[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs13113112	0.87[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs13114751	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs13116504	0.89[AMR][1000 genomes];0.88[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs13126596	0.82[AMR][1000 genomes]
rs13129661	0.84[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs13133044	0.89[AMR][1000 genomes];0.88[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs13133522	0.80[AMR][1000 genomes]
rs13151285	0.86[AMR][1000 genomes]
rs13435802	0.86[AMR][1000 genomes];0.86[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs1397608	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs1511015	0.86[AMR][1000 genomes];0.85[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs1511017	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs1511018	0.87[AMR][1000 genomes];0.82[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs1511019	0.87[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs1511025	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs1546502	0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];0.98[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs1546503	0.89[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs1546504	0.98[AFR][1000 genomes];0.97[AMR][1000 genomes];0.98[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs1546505	0.98[AFR][1000 genomes];0.99[AMR][1000 genomes];0.98[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs1546506	0.89[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs1551	0.86[AMR][1000 genomes];0.80[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs17049949	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs17595608	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs1980024	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs1980025	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs1980026	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs1980027	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs2002047	0.83[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs2002049	0.85[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs2017057	0.91[AFR][1000 genomes];0.97[AMR][1000 genomes];0.97[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs2036856	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs2036857	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs2036860	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs2389802	0.80[AMR][1000 genomes]
rs28363929	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs28373117	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs28374891	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs28403131	0.83[AMR][1000 genomes];0.81[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs28419773	0.85[AFR][1000 genomes];0.90[AMR][1000 genomes];0.88[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs28491261	0.80[AMR][1000 genomes]
rs28502463	0.86[EUR][1000 genomes];0.80[ASN][1000 genomes]
rs28555550	0.85[AFR][1000 genomes];0.90[AMR][1000 genomes];0.88[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs28572238	0.86[AMR][1000 genomes]
rs28633994	0.83[AMR][1000 genomes];0.83[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs28643450	0.89[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs28652763	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs28713555	0.89[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs28714195	0.86[AMR][1000 genomes]
rs28857482	0.80[AMR][1000 genomes]
rs2964	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs34425882	0.89[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs34585914	0.90[AMR][1000 genomes];0.87[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs34616304	0.86[AMR][1000 genomes];0.85[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs34630083	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs34685788	0.85[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs34818745	0.81[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs34913743	0.80[AMR][1000 genomes]
rs35197422	0.86[AMR][1000 genomes];0.85[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs35271032	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs35434465	0.87[AMR][1000 genomes];0.85[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs35643470	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs35916640	0.86[AMR][1000 genomes];0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs3749591	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs3864141	0.84[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs4079144	0.80[AMR][1000 genomes]
rs4107728	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs4145951	0.86[AMR][1000 genomes];0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs4309825	0.86[AMR][1000 genomes]
rs4345162	0.86[AMR][1000 genomes]
rs4443261	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs4472123	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs4604043	0.86[AMR][1000 genomes]
rs56386062	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs59394118	0.87[AMR][1000 genomes];0.83[ASN][1000 genomes]
rs59866101	0.81[AMR][1000 genomes]
rs66900435	0.81[AMR][1000 genomes];0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs67073020	0.84[AMR][1000 genomes]
rs68128210	0.82[AMR][1000 genomes]
rs6814412	0.87[AMR][1000 genomes];0.84[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs6815725	0.86[AMR][1000 genomes];0.82[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs6837898	0.87[AMR][1000 genomes];0.86[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs6838236	0.87[AMR][1000 genomes];0.89[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs6838617	0.86[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs6845714	0.80[AMR][1000 genomes]
rs6846442	0.80[AMR][1000 genomes]
rs6847075	0.87[AMR][1000 genomes];0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs6847248	0.86[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs6848580	0.89[AMR][1000 genomes];0.81[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs6849889	0.89[AMR][1000 genomes];0.87[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs6857105	0.96[AMR][1000 genomes];0.98[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs714899	0.81[AMR][1000 genomes];0.89[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs72676045	0.88[AFR][1000 genomes];0.96[AMR][1000 genomes];0.97[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs72676046	0.87[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7437420	0.86[AMR][1000 genomes]
rs7659194	0.85[AFR][1000 genomes];0.90[AMR][1000 genomes];0.88[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs7665192	0.86[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs7671978	0.84[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs7672129	0.87[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs7672372	0.87[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7672493	0.95[AFR][1000 genomes];0.97[AMR][1000 genomes];0.95[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7672594	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7672778	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7673476	0.83[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7684942	0.83[AMR][1000 genomes];0.80[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs7685268	0.85[AMR][1000 genomes];0.82[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs7689729	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7695996	0.84[AMR][1000 genomes]
rs7696465	0.84[AMR][1000 genomes]
rs7696649	0.84[AMR][1000 genomes]
rs7696857	0.83[AMR][1000 genomes]
rs7696875	0.82[AMR][1000 genomes]
rs878372	0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs878376	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs907204	0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs907205	0.90[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs938056	0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs9991166	0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs9991959	0.90[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs9993347	0.89[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs9995045	0.80[AMR][1000 genomes]
rs9995234	0.82[AMR][1000 genomes]
rs9996494	0.87[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs9996644	0.87[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs9998953	0.82[ASN][1000 genomes]
rs9999724	0.81[AMR][1000 genomes];0.90[EUR][1000 genomes];0.97[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:5 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv916641	chr4:119780023-120777320	Strong transcription Weak transcription Enhancers Active TSS Flanking Active TSS Bivalent/Poised TSS Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	72 gene(s)	inside rSNPs	diseases
2	nsv1012868	chr4:120014630-120464880	Enhancers Flanking Active TSS Active TSS Weak transcription Genic enhancers ZNF genes & repeats Strong transcription Bivalent/Poised TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	58 gene(s)	inside rSNPs	diseases
3	nsv537232	chr4:120014630-120464880	Weak transcription Enhancers Strong transcription ZNF genes & repeats Genic enhancers Active TSS Flanking Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	58 gene(s)	inside rSNPs	diseases
4	nsv428769	chr4:120205572-120363323	Strong transcription Enhancers Flanking Active TSS Weak transcription Active TSS Genic enhancers Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	15 gene(s)	inside rSNPs	diseases
5	nsv879840	chr4:120227419-120257417	Weak transcription Enhancers Active TSS Flanking Active TSS Strong transcription ZNF genes & repeats Genic enhancers	TF binding region CpG island Chromatin interactive region	6 gene(s)	inside rSNPs	diseases

mRNA abundance (count:11)

SNP	Gene	Cis/trans	Tissue	Source
rs878373	RP11-33B1.1	cis	Stomach	GTEx
rs878373	RP11-33B1.1	cis	Nerve Tibial	GTEx
rs878373	RP11-33B1.1	cis	Whole Blood	GTEx
rs878373	RP11-33B1.1	cis	lung	GTEx
rs878373	RP11-384K6.6	cis	Whole Blood	GTEx
rs878373	RP11-33B1.1	cis	Esophagus Mucosa	GTEx
rs878373	RP11-33B1.1	cis	Thyroid	GTEx
rs878373	RP11-33B1.1	cis	Heart Left Ventricle	GTEx
rs878373	RP11-33B1.4	cis	Whole Blood	GTEx
rs878373	LOC645513	Cis_1M	lymphoblastoid	RTeQTL
rs878373	FLJ14186///LOC284701///LOC441124///LOC728624	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:15 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr4:120222000-120251000	Weak transcription	Sigmoid Colon	Sigmoid Colon
2	chr4:120222200-120244600	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
3	chr4:120222400-120240800	Weak transcription	Rectal Mucosa Donor 29	rectum
4	chr4:120222800-120240800	Weak transcription	Rectal Mucosa Donor 31	rectum
5	chr4:120225000-120238800	Weak transcription	Fetal Intestine Small	intestine
6	chr4:120228200-120238600	Weak transcription	Fetal Intestine Large	intestine
7	chr4:120229200-120238400	Weak transcription	Duodenum Mucosa	Duodenum
8	chr4:120234200-120237600	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
9	chr4:120235000-120239400	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
10	chr4:120235400-120238000	Enhancers	NHDF-Ad	bronchial
11	chr4:120235600-120251000	Weak transcription	Left Ventricle	heart
12	chr4:120235800-120241800	Weak transcription	Duodenum Smooth Muscle	Duodenum
13	chr4:120237000-120237600	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
14	chr4:120237000-120238800	Weak transcription	NHLF	lung
15	chr4:120237200-120238200	Weak transcription	Osteobl	bone

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