Variant report

Variant	esv1825920
Chromosome Location	chr16:70236877-70280052
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:1147)
CpG islands
(count:61)
Chromatin interactive
region (count:4)
LncRNA
region (count:1)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:1147 , 50 per page) page: 1 2 3 4 5 6 7 ... 23

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	BATF	chr16:70275352-70275629	GM12878	blood:	n/a	n/a
2	BATF	chr16:70269207-70269408	GM12878	blood:	n/a	n/a
3	BATF	chr16:70274531-70275234	GM12878	blood:	n/a	n/a
4	BATF	chr16:70275330-70275612	GM12878	blood:	n/a	n/a
5	BATF	chr16:70259711-70260057	GM12878	blood:	n/a	n/a
6	BATF	chr16:70266179-70266523	GM12878	blood:	n/a	n/a
7	BATF	chr16:70269196-70269455	GM12878	blood:	n/a	n/a
8	BATF	chr16:70252521-70252845	GM12878	blood:	n/a	chr16:70252736-70252746
9	BATF	chr16:70277954-70278184	GM12878	blood:	n/a	n/a
10	BATF	chr16:70272645-70272986	GM12878	blood:	n/a	n/a
11	BATF	chr16:70274761-70275229	GM12878	blood:	n/a	n/a
12	BATF	chr16:70266143-70266490	GM12878	blood:	n/a	n/a
13	BATF	chr16:70249268-70249471	GM12878	blood:	n/a	n/a
14	BATF	chr16:70272693-70272978	GM12878	blood:	n/a	n/a
15	BATF	chr16:70242991-70243230	GM12878	blood:	n/a	n/a
16	BATF	chr16:70251089-70251362	GM12878	blood:	n/a	n/a
17	BATF	chr16:70243288-70243494	GM12878	blood:	n/a	n/a
18	BATF	chr16:70265769-70265977	GM12878	blood:	n/a	n/a
19	BATF	chr16:70270340-70270551	GM12878	blood:	n/a	n/a
20	BATF	chr16:70251010-70251261	GM12878	blood:	n/a	n/a
21	BCL11A	chr16:70274544-70275641	GM12878	blood:	n/a	n/a
22	BCL11A	chr16:70256979-70257253	GM12878	blood:	n/a	n/a
23	BCL11A	chr16:70252607-70252876	GM12878	blood:	n/a	n/a
24	BCL11A	chr16:70249059-70249253	GM12878	blood:	n/a	n/a
25	BCL11A	chr16:70256901-70257158	GM12878	blood:	n/a	n/a
26	BCL11A	chr16:70256507-70256821	GM12878	blood:	n/a	n/a
27	BCL11A	chr16:70260079-70260328	GM12878	blood:	n/a	n/a
28	BCL11A	chr16:70266128-70266474	GM12878	blood:	n/a	n/a
29	BCL11A	chr16:70242982-70243227	GM12878	blood:	n/a	n/a
30	BCL11A	chr16:70265235-70265407	GM12878	blood:	n/a	n/a
31	BCL11A	chr16:70264796-70265164	GM12878	blood:	n/a	n/a
32	BCL11A	chr16:70247717-70247954	GM12878	blood:	n/a	n/a
33	BCL11A	chr16:70252674-70252910	GM12878	blood:	n/a	n/a
34	BCL11A	chr16:70267253-70267439	GM12878	blood:	n/a	n/a
35	BCL11A	chr16:70274796-70275305	GM12878	blood:	n/a	n/a
36	BCL11A	chr16:70272703-70272967	GM12878	blood:	n/a	n/a
37	BCL11A	chr16:70274569-70274791	GM12878	blood:	n/a	n/a
38	BCL11A	chr16:70275340-70275579	GM12878	blood:	n/a	n/a
39	BCL11A	chr16:70253466-70253640	GM12878	blood:	n/a	n/a
40	BCL11A	chr16:70272603-70273149	GM12878	blood:	n/a	n/a
41	BCL11A	chr16:70273183-70273430	GM12878	blood:	n/a	n/a
42	BCL11A	chr16:70266040-70266508	GM12878	blood:	n/a	n/a
43	BHLHE40	chr16:70260045-70260625	HepG2	liver:	n/a	n/a
44	BHLHE40	chr16:70277485-70277753	HepG2	liver:	n/a	n/a
45	BHLHE40	chr16:70254937-70255237	HepG2	liver:	n/a	n/a
46	BHLHE40	chr16:70249020-70249505	HepG2	liver:	n/a	n/a
47	BHLHE40	chr16:70254336-70254859	HepG2	liver:	n/a	n/a
48	BHLHE40	chr16:70242942-70243167	HepG2	liver:	n/a	n/a
49	BHLHE40	chr16:70247348-70248139	HepG2	liver:	n/a	n/a
50	BHLHE40	chr16:70264795-70265113	HepG2	liver:	n/a	n/a

(count:61 , 50 per page) page: 1 2

No.	Chromosome Location	Cell Line	Cell type	Cell Stage
1	chr16:70259186-70259236	HCPEpiC	choroid plexus:	n/a
2	chr16:70259186-70259236	PFSK-1	brain:	n/a
3	chr16:70259186-70259236	HCM	heart:	n/a
4	chr16:70259186-70259236	LNCaP	prostate:	n/a
5	chr16:70259186-70259236	SAEC	small airway:	n/a
6	chr16:70259186-70259236	GM06990	blood:	n/a
7	chr16:70259186-70259236	GM12891	blood:	n/a
8	chr16:70259186-70259236	HIPEpiC	eye:	n/a
9	chr16:70259186-70259236	CMK	blood:	n/a
10	chr16:70259186-70259236	H1-hESC	embryonic stem cell:	embryo
11	chr16:70259186-70259236	HCF	heart:	n/a
12	chr16:70259186-70259236	NHBE	bronchial:	n/a
13	chr16:70259186-70259236	HRPEpiC	eye:	n/a
14	chr16:70259186-70259236	ovcar-3	ovarian:	n/a
15	chr16:70259186-70259236	NHDF-neo	bronchial:	n/a
16	chr16:70259186-70259236	HCT-116	colon:	n/a
17	chr16:70259186-70259236	SK-N-MC	brain:	n/a
18	chr16:70259186-70259236	Hepatocyte	liver:	n/a
19	chr16:70259186-70259236	GM12878	blood:	n/a
20	chr16:70259186-70259236	HPAEpiC	pulmonary alveolar:	n/a
21	chr16:70259186-70259236	HRCEpiC	kidney:	n/a
22	chr16:70259186-70259236	GM19239	blood:	n/a
23	chr16:70259186-70259236	HUVEC	blood vessel:	n/a
24	chr16:70259186-70259236	NB4	blood:	n/a
25	chr16:70259186-70259236	AG10803	skin:	n/a
26	chr16:70259186-70259236	BE2_C	brain:	n/a
27	chr16:70259186-70259236	SKMC	muscle:	n/a
28	chr16:70259186-70259236	A549	lung:	n/a
29	chr16:70259186-70259236	Jurkat	blood:	n/a
30	chr16:70259186-70259236	HEK293	kidney:	embryo
31	chr16:70259186-70259236	HL-60	blood:	n/a
32	chr16:70259186-70259236	HMEC	breast:	n/a
33	chr16:70259186-70259236	NH-A	brain:	n/a
34	chr16:70259186-70259236	RPTEC	kidney:	n/a
35	chr16:70259186-70259236	AG04449	skin:	fetal
36	chr16:70259186-70259236	AG09319	gingival:	n/a
37	chr16:70259186-70259236	HAEpiC	amniotic membrane:	n/a
38	chr16:70259186-70259236	PANC-1	pancreas:	n/a
39	chr16:70259186-70259236	T-47D	breast:	n/a
40	chr16:70259186-70259236	PrEC	prostate:	n/a
41	chr16:70259186-70259236	SK-N-SH_RA	brain:	n/a
42	chr16:70259186-70259236	ProgFib	skin:	n/a
43	chr16:70259186-70259236	HNPCEpiC	eye:	n/a
44	chr16:70259186-70259236	AG09309	skin:	n/a
45	chr16:70259186-70259236	NT2-D1	testis:	n/a
46	chr16:70259186-70259236	MCF-7	breast:	n/a
47	chr16:70259186-70259236	AoSMC	blood vessel:	n/a
48	chr16:70259186-70259236	ECC-1	luminal epithelium:	n/a
49	chr16:70259186-70259236	Caco-2	colon:	n/a
50	chr16:70259186-70259236	K562	blood:	n/a

(count:4 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr16:70279273..70282169-chr16:70284255..70286204,3	K562	blood:
2	chr16:70279244..70282169-chr16:70284255..70286230,4	K562	blood:
3	chr16:70245449..70247912-chr16:70284379..70285973,2	MCF-7	breast:
4	chr16:70278247..70283453-chr16:70284015..70287841,6	MCF-7	breast:

(count:1 , 50 per page) page: 1

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-DDX19B-2	chr16:70273803-70273904	NONHSAT143414

No data

Variant related genes	Relation type
ENSG00000238734	TF binding region
ENSG00000269866	TF binding region
ENSG00000269746	TF binding region
ENSG00000261556	TF binding region
ENSG00000238734	CpG island
ENSG00000269866	CpG island
ENSG00000269746	CpG island
ENSG00000261556	CpG island
ENSG00000223496	chromatin interactions

Extended variants
information (count: 1696 )
Associated
traits (count: 71 )

Variant overlapped rSNPs/rCNVs (count:1696 , 50 per page) page: 1 2 3 4 5 6 7 ... 34

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs149822159	chr16:70236887-70236888	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
2	rs547300027	chr16:70236888-70236889	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
3	rs371285900	chr16:70236899-70236900	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
4	rs571870663	chr16:70236900-70236901	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
5	rs184915892	chr16:70236904-70236905	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
6	rs62049375	chr16:70236911-70236912	Weak transcription	n/a	n/a	Overlapped CNVs	mRNA abundance
7	rs569329506	chr16:70236945-70236946	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
8	rs536793137	chr16:70236946-70236947	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
9	rs554991187	chr16:70236982-70236983	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
10	rs573221672	chr16:70237003-70237004	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
11	rs186626123	chr16:70237008-70237009	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
12	rs553202511	chr16:70237011-70237012	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
13	rs577874411	chr16:70237102-70237103	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
14	rs147119756	chr16:70237111-70237112	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
15	rs367559936	chr16:70237134-70237135	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
16	rs563146035	chr16:70237148-70237149	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
17	rs530518505	chr16:70237193-70237194	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
18	rs74496105	chr16:70237225-70237226	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
19	rs398100270	chr16:70237234-70237235	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
20	rs542348640	chr16:70237236-70237237	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
21	rs560699293	chr16:70237249-70237250	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
22	rs528060528	chr16:70237342-70237343	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
23	rs555700747	chr16:70237371-70237372	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
24	rs191287774	chr16:70237402-70237403	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
25	rs571868077	chr16:70237455-70237456	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
26	rs532695515	chr16:70237478-70237479	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
27	rs551189812	chr16:70237511-70237512	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
28	rs9673623	chr16:70237550-70237551	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
29	rs536730970	chr16:70237554-70237555	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
30	rs555130647	chr16:70237568-70237569	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
31	rs566876708	chr16:70237571-70237572	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
32	rs371363415	chr16:70237579-70237580	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
33	rs575396517	chr16:70237594-70237595	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
34	rs534164589	chr16:70237614-70237615	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
35	rs370622841	chr16:70237634-70237635	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
36	rs538152520	chr16:70237641-70237642	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
37	rs112299064	chr16:70237647-70237648	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
38	rs199584701	chr16:70237648-70237649	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
39	rs8062930	chr16:70237653-70237654	Weak transcription	n/a	n/a	Overlapped CNVs	mRNA abundance
40	rs8062651	chr16:70237659-70237660	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
41	rs141688643	chr16:70237665-70237666	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
42	rs560661742	chr16:70237671-70237672	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
43	rs8063042	chr16:70237677-70237678	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
44	rs375089800	chr16:70237683-70237684	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
45	rs543073208	chr16:70237689-70237690	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
46	rs561873682	chr16:70237695-70237696	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
47	rs369597122	chr16:70237701-70237702	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
48	rs550937890	chr16:70237706-70237707	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
49	rs564362021	chr16:70237707-70237708	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
50	rs532976123	chr16:70237712-70237713	Weak transcription	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:71)

Disease	PMID	Source
Esophageal squamous carcinoma	21637470	CNVD
Glioblastoma multiforme	21080181	CNVD
Acute lymphoblastic leukemia	17690704	CNVD
Autism	19415332	CNVD
Medulloblastoma	21979893	CNVD
Non-syndromic sensorineural hearing loss	22037309	CNVD
Schizophrenia	22958593	CNVD
Breast cancer	20668451	CNVD
Cancer	20668451	CNVD
Lung cancer	20668451	CNVD
Ovarian cancer	20668451	CNVD
Pancreas cancer	20668451	CNVD
Prostate cancer	20668451	CNVD
Hodgkin''s lymphoma	17606441	CNVD
Autism	22495311	CNVD
Wilms tumour	21544195	CNVD
Prostate cancer	18632612	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Breast cancer	17850661	CNVD
Breast cancer	16702952	CNVD
Medulloblastoma	16968546	CNVD
Prostate cancer	19242612	CNVD
Cancer	22429812	CNVD
Ewing''s sarcoma	21437220	CNVD
Ewing''s sarcoma	22429812	CNVD
Melanoma	18172304	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	20837533	CNVD
Breast cancer	21264507	CNVD
Glioblastoma multiforme	19960244	CNVD
Hepatocellular carcinoma	22174799	CNVD
Multiple myeloma	21628407	CNVD
Ovarian cancer	22174824	CNVD
Breast cancer	21858162	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Ewing''s sarcoma	17952124	CNVD
Breast cancer	17001317	CNVD
Breast cancer	17133270	CNVD
Acute lymphoblastic leukemia	22237106	CNVD
Acute lymphoblastic leukemia	20067559	CNVD
Breast cancer	17603634	CNVD
Prostate cancer	16573809	CNVD
Chordoma	18071362	CNVD
Prostate cancer	17245344	CNVD
Basal cell lymphoma	16317097	CNVD
Diffuse large b-cell lymphoma	16317097	CNVD
Malignant peripheral nerve sheath tumor	18522746	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
High-grade prostatic intraepithelial neoplasia	16573809	CNVD
T-cell prolymphocytic leukemia	17713554	CNVD
Acute myeloid leukemia	16864856	CNVD
Infiltrating lobular breast cancer	19191266	CNVD
T-cell lymphomas	19863542	CNVD
small cell lung cancer	20016488	CNVD
T-cell acute lymphoblastic leukemia	18185524	CNVD
Basal cell lymphoma	19029149	CNVD
Diffuse large b-cell lymphoma	19029149	CNVD
Hepatocellular carcinoma	16750200	CNVD
Medulloblastoma	16783165	CNVD
Neuroblastoma	21899760	CNVD
Bladder cancer	21909424	CNVD
Lung cancer	18438408	CNVD
Breast cancer	21364760	CNVD
Myelofibrosis	22110671	CNVD
Glioblastoma multiforme	18628472	CNVD
Breast cancer	21806811	CNVD
Pancreatic ductal adenocarcinoma	19077451	CNVD
Autism	20841430	CNVD
Ependymoma	20639864	CNVD
Pancreatic cancer	17952125	CNVD
Breast cancer	22522925	CNVD

Chromatin state (count:548 , 50 per page) page: 1 2 3 4 5 6 7 ... 11

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr16:70226600-70252600	Weak transcription	Adipose Nuclei	Adipose
2	chr16:70231200-70252000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
3	chr16:70231400-70258600	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
4	chr16:70232400-70284800	Weak transcription	Spleen	Spleen
5	chr16:70232600-70241400	Weak transcription	Primary hematopoietic stem cells short term culture	blood
6	chr16:70233200-70246600	Weak transcription	Fetal Stomach	stomach
7	chr16:70233200-70253600	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
8	chr16:70233200-70283400	Weak transcription	Primary hematopoietic stem cells	blood
9	chr16:70233200-70283600	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
10	chr16:70233600-70246600	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
11	chr16:70233600-70253600	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
12	chr16:70233800-70238600	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
13	chr16:70233800-70252200	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
14	chr16:70234800-70260800	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
15	chr16:70235600-70241000	Weak transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
16	chr16:70235600-70247400	Weak transcription	Fetal Intestine Small	intestine
17	chr16:70235600-70258600	Weak transcription	Pancreas	Pancrea
18	chr16:70235600-70284200	Weak transcription	Brain Cingulate Gyrus	brain
19	chr16:70236200-70258600	Weak transcription	Thymus	Thymus
20	chr16:70237000-70237200	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
21	chr16:70237000-70237200	Enhancers	Sigmoid Colon	Sigmoid Colon
22	chr16:70237000-70258600	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
23	chr16:70237000-70258800	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
24	chr16:70237200-70247000	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
25	chr16:70237200-70267200	Weak transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
26	chr16:70237200-70284800	Weak transcription	Sigmoid Colon	Sigmoid Colon
27	chr16:70238200-70240000	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
28	chr16:70238400-70240000	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
29	chr16:70238400-70246200	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
30	chr16:70238400-70253400	Weak transcription	Duodenum Mucosa	Duodenum
31	chr16:70238400-70274600	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
32	chr16:70238600-70247200	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
33	chr16:70238600-70252200	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
34	chr16:70238600-70284800	Weak transcription	Esophagus	oesophagus
35	chr16:70238800-70252200	Weak transcription	Primary B cells from peripheral blood	blood
36	chr16:70238800-70253400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
37	chr16:70238800-70260400	Weak transcription	Fetal Brain Female	brain
38	chr16:70238800-70283400	Weak transcription	NHEK	skin
39	chr16:70238800-70283600	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
40	chr16:70239000-70260600	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
41	chr16:70239000-70266800	Weak transcription	Aorta	Aorta
42	chr16:70239200-70256800	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
43	chr16:70239200-70260600	Weak transcription	H1 Cell Line	embryonic stem cell
44	chr16:70239600-70240000	Weak transcription	Primary monocytes fromperipheralblood	blood
45	chr16:70239600-70246200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
46	chr16:70239600-70246600	Weak transcription	Primary T cells fromperipheralblood	blood
47	chr16:70239600-70247600	Weak transcription	Fetal Intestine Large	intestine
48	chr16:70239600-70283400	Weak transcription	Brain Angular Gyrus	brain
49	chr16:70239800-70247200	Weak transcription	Dnd41	blood
50	chr16:70239800-70252200	Weak transcription	Primary T helper naive cells fromperipheralblood	blood

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links