Variant report

Variant	esv2761835
Chromosome Location	chr14:46145141-46231045
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	CBX3	chr14:46213002-46213438	HCT-116	colon:	n/a	n/a
2	CEBPB	chr14:46170313-46170577	HepG2	liver:	n/a	chr14:46170421-46170432
3	CEBPB	chr14:46195157-46195161	H1-hESC	embryonic stem cell:	n/a	n/a
4	CTCF	chr14:46185800-46185950	HFF-Myc	foreskin:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
5	CTCF	chr14:46185762-46186067	GM12878	blood:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
6	CTCF	chr14:46185800-46185950	SK-N-SH_RA	brain:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
7	CTCF	chr14:46185800-46185950	GM12875	blood:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
8	CTCF	chr14:46185820-46185970	Hela-S3	cervix:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
9	CTCF	chr14:46185600-46185750	BJ	skin:	n/a	n/a
10	CTCF	chr14:46147346-46147671	MCF-7	breast:	n/a	chr14:46147550-46147568
11	CTCF	chr14:46185780-46185930	HFF	foreskin:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
12	CTCF	chr14:46185780-46185930	HepG2	liver:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
13	CTCF	chr14:46185728-46186084	T-47D	breast:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
14	CTCF	chr14:46185841-46186048	MCF-7	breast:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
15	CTCF	chr14:46147488-46147654	HUVEC	blood vessel:	n/a	chr14:46147550-46147568
16	CTCF	chr14:46185641-46186214	MCF-7	breast:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
17	CTCF	chr14:46185800-46185950	SAEC	small airway:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
18	CTCF	chr14:46185840-46185990	NHEK	skin:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
19	CTCF	chr14:46185760-46185910	GM12873	blood:	n/a	n/a
20	CTCF	chr14:46147380-46147530	HFF	foreskin:	n/a	n/a
21	CTCF	chr14:46185800-46185950	RPTEC	kidney:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
22	CTCF	chr14:46147460-46147610	HA-sp	spinal cord:	n/a	chr14:46147550-46147568
23	CTCF	chr14:46147400-46147550	MCF-7	breast:	n/a	n/a
24	CTCF	chr14:46185800-46185950	MCF-7	breast:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
25	CTCF	chr14:46188014-46188095	LNCaP	prostate:	n/a	n/a
26	CTCF	chr14:46210422-46210429	K562	blood:	n/a	n/a
27	CTCF	chr14:46147440-46147590	AG09309	skin:	n/a	chr14:46147550-46147568
28	CTCF	chr14:46188001-46188103	NHEK	skin:	n/a	n/a
29	CTCF	chr14:46185851-46186031	ProgFib	skin:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
30	CTCF	chr14:46185809-46186012	LNCaP	prostate:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
31	CTCF	chr14:46188020-46188170	HCPEpiC	choroid plexus:	n/a	n/a
32	CTCF	chr14:46147580-46147730	HFF	foreskin:	n/a	n/a
33	CTCF	chr14:46187940-46188090	MCF-7	breast:	n/a	n/a
34	CTCF	chr14:46147414-46147682	IMR90	lung:	n/a	chr14:46147550-46147568
35	CTCF	chr14:46188100-46188250	HFF	foreskin:	n/a	n/a
36	CTCF	chr14:46188020-46188170	RPTEC	kidney:	n/a	n/a
37	CTCF	chr14:46185800-46185950	GM12865	blood:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
38	CTCF	chr14:46185860-46186010	HMF	breast:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
39	CTCF	chr14:46185820-46185970	WERI-Rb-1	eye:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
40	CTCF	chr14:46185800-46185950	NB4	blood:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
41	CTCF	chr14:46185800-46185950	GM12864	blood:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
42	CTCF	chr14:46187980-46188130	NHEK	skin:	n/a	n/a
43	CTCF	chr14:46195760-46195910	HepG2	liver:	n/a	n/a
44	CTCF	chr14:46185800-46185950	BE2_C	brain:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
45	CTCF	chr14:46185760-46185910	GM12878	blood:	n/a	n/a
46	CTCF	chr14:46147280-46147430	HBMEC	blood vessel:	n/a	n/a
47	CTCF	chr14:46185840-46185990	HCPEpiC	choroid plexus:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
48	CTCF	chr14:46185846-46186017	Kidney_OC	kidney:	n/a	chr14:46185903-46185921 chr14:46185906-46185915
49	CTCF	chr14:46187860-46188010	NHEK	skin:	n/a	n/a
50	CTCF	chr14:46185718-46186173	MCF-7	breast:	n/a	chr14:46185903-46185921 chr14:46185906-46185915

No.	Distal block	Cell Line	Cell type
1	chr14:46147083..46148164-chr14:46409225..46410271,4	MCF-7	breast:
2	chr14:46147376..46147982-chr14:46279500..46280082,2	MCF-7	breast:
3	chr14:46185495..46186349-chr14:46307923..46308469,2	MCF-7	breast:
4	chr14:46182590..46185086-chr14:46185381..46187428,2	MCF-7	breast:
5	chr14:46185447..46186022-chr14:46279860..46280372,3	MCF-7	breast:
6	chr10:29154738..29155346-chr14:46193775..46194564,2	MCF-7	breast:
7	chr14:46185365..46185918-chr14:46409681..46410218,2	MCF-7	breast:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-MIS18BP1-1	chr14:46175461-46175705	ENSG00000258616
2	lnc-FANCM-5	chr14:46217809-46217893	NONHSAT036668
3	lnc-FANCM-5	chr14:46179124-46179145	NONHSAT036668
4	lnc-MIS18BP1-1	chr14:46184553-46185084	NONHSAT036669
5	lnc-MIS18BP1-1	chr14:46175495-46175705	XLOC_011012
6	lnc-MIS18BP1-1	chr14:46183487-46183623	ENSG00000258616
7	lnc-MIS18BP1-1	chr14:46175453-46175705	ENSG00000258616
8	lnc-MIS18BP1-1	chr14:46181102-46181156	ENSG00000258616
9	lnc-FANCM-5	chr14:46213235-46213370	NONHSAT036668
10	lnc-MIS18BP1-1	chr14:46183487-46183656	ENSG00000258616
11	lnc-FANCM-5	chr14:46213166-46213370	NONHSAT036671
12	lnc-MIS18BP1-1	chr14:46177039-46177101	ENSG00000258616
13	lnc-MIS18BP1-1	chr14:46175463-46175705	ENSG00000258616
14	lnc-MIS18BP1-1	chr14:46175461-46175705	ENSG00000258616
15	lnc-FANCM-5	chr14:46217809-46217840	NONHSAT036670
16	lnc-FANCM-5	chr14:46213235-46213370	NONHSAT036670
17	lnc-FANCM-5	chr14:46213325-46213370	XLOC_010816
18	lnc-FANCM-5	chr14:46195358-46195474	NONHSAT036670
19	lnc-FANCM-5	chr14:46217809-46217860	XLOC_010816
20	lnc-MIS18BP1-1	chr14:46181102-46181226	XLOC_011012
21	lnc-MIS18BP1-1	chr14:46184553-46185155	ENSG00000258616
22	lnc-MIS18BP1-1	chr14:46183487-46183634	ENSG00000258616
23	lnc-FANCM-5	chr14:46217539-46217865	NONHSAT036671
24	lnc-MIS18BP1-1	chr14:46184553-46185114	NONHSAT036666
25	lnc-MIS18BP1-1	chr14:46184553-46184690	ENSG00000258616
26	lnc-MIS18BP1-1	chr14:46177058-46177101	NONHSAT036666
27	lnc-MIS18BP1-1	chr14:46181102-46181156	ENSG00000258616
28	lnc-MIS18BP1-1	chr14:46184553-46184894	ENSG00000258616
29	lnc-MIS18BP1-1	chr14:46183506-46183653	NONHSAT036669
30	lnc-MIS18BP1-1	chr14:46175475-46175705	ENSG00000258616

Variant related genes	Relation type
ENSG00000258616	TF binding region
ENSG00000258700	chromatin interactions
ENSG00000258616	chromatin interactions
CNOT6L	miRNA target sites
IGF2BP3	miRNA target sites

Extended variants
information (count: 1555 )
Associated
traits (count: 56 )

Variant overlapped rSNPs/rCNVs (count:1555 , 50 per page) page: 1 2 3 4 5 6 7 ... 32

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs74753400	chr14:46146405-46146406	Enhancers	n/a	n/a	Overlapped CNVs	n/a
2	rs558307676	chr14:46146413-46146414	Enhancers	n/a	n/a	Overlapped CNVs	n/a
3	rs200837534	chr14:46146461-46146462	Enhancers	n/a	n/a	Overlapped CNVs	n/a
4	rs557102422	chr14:46146472-46146473	Enhancers	n/a	n/a	Overlapped CNVs	n/a
5	rs569255369	chr14:46146575-46146576	Enhancers	n/a	n/a	Overlapped CNVs	n/a
6	rs536313093	chr14:46146590-46146591	Enhancers	n/a	n/a	Overlapped CNVs	n/a
7	rs112578904	chr14:46146621-46146622	Enhancers	n/a	n/a	Overlapped CNVs	n/a
8	rs17116326	chr14:46146672-46146673	Enhancers	n/a	n/a	Overlapped CNVs	mRNA abundance
9	rs540084858	chr14:46146718-46146719	Enhancers	n/a	n/a	Overlapped CNVs	n/a
10	rs140761452	chr14:46146808-46146809	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
11	rs144699237	chr14:46146809-46146810	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
12	rs112348025	chr14:46146843-46146844	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
13	rs371948622	chr14:46146849-46146850	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
14	rs78994707	chr14:46146850-46146851	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
15	rs369744340	chr14:46146853-46146854	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
16	rs117416751	chr14:46146888-46146889	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
17	rs555172753	chr14:46146971-46146972	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
18	rs138519553	chr14:46146996-46146997	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
19	rs529710689	chr14:46147020-46147021	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
20	rs145893593	chr14:46147028-46147029	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
21	rs560200324	chr14:46147074-46147075	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
22	rs187617526	chr14:46147087-46147088	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
23	rs547246846	chr14:46147113-46147114	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
24	rs571946711	chr14:46147146-46147147	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
25	rs575857840	chr14:46147154-46147155	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
26	rs373529683	chr14:46147184-46147185	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
27	rs551270468	chr14:46147188-46147189	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
28	rs569115912	chr14:46147240-46147241	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
29	rs138453751	chr14:46147307-46147308	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
30	rs554763325	chr14:46147356-46147357	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
31	rs566665202	chr14:46147368-46147369	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
32	rs533723612	chr14:46147373-46147374	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
33	rs367544380	chr14:46147396-46147397	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
34	rs149644684	chr14:46147437-46147438	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
35	rs7160658	chr14:46147441-46147442	Weak transcription	Chromatin interactive region	1 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
36	rs537714259	chr14:46147515-46147516	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
37	rs556433276	chr14:46147540-46147541	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
38	rs144323431	chr14:46147559-46147560	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
39	rs541859639	chr14:46147578-46147579	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
40	rs559974528	chr14:46147596-46147597	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
41	rs115308022	chr14:46147610-46147611	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
42	rs555980354	chr14:46147681-46147682	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
43	rs565443410	chr14:46147694-46147695	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
44	rs532761140	chr14:46147716-46147717	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
45	rs148778404	chr14:46147728-46147729	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
46	rs190840568	chr14:46147738-46147739	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
47	rs141460805	chr14:46147743-46147744	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
48	rs147494582	chr14:46147771-46147772	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
49	rs566605921	chr14:46147896-46147897	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
50	rs534002363	chr14:46147927-46147928	Weak transcription Enhancers	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a

Variant related diseases (count:56)

Disease	PMID	Source
Esophageal cancer	21851588	CNVD
Ewing''s sarcoma	21437220	CNVD
Glioblastoma multiforme	21080181	CNVD
Retinoblastoma	21504564	CNVD
High-proliferative meningiomas	17937814	CNVD
Thoracic aortic aneurysm	21092924	CNVD
Autism	22495311	CNVD
Non-small cell lung cancer	21044232	CNVD
Renal cell carcinoma	19461508	CNVD
Cancer	21637783	CNVD
Colorectal cancer	20709793	CNVD
Melanoma	18172304	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Medulloblastoma	21979893	CNVD
Oral cancer	21386901	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	21264507	CNVD
Hepatocellular carcinoma	22174799	CNVD
Colorectal cancer	16774939	CNVD
Neuroblastoma	19435921	CNVD
Colorectal cancer	19359472	CNVD
Breast cancer	17899364	CNVD
Gastrointestinal stromal cancer	19259404	CNVD
Gastrointestinal stromal cancer	17535989	CNVD
Monoclonal gammopathy of undetermined significance	17077331	CNVD
Paraganglioma	17535989	CNVD
Pulmonary chondroma	17535989	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
Gastrointestinal stromal cancer	16982739	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Gastrointestinal stromal cancer	20818650	CNVD
Renal cell carcinoma	21668985	CNVD
Chronic myeloid leukemia	20724749	CNVD
Hodgkin''s lymphoma	17606441	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Wilms tumour	21544195	CNVD
Lung cancer	18438408	CNVD
Urothelial carcinoma	21177765	CNVD
Multiple myeloma	17550852	CNVD
Breast cancer	21785460	CNVD
Colorectal cancer	16272173	CNVD
Prostate cancer	18632612	CNVD
small cell lung cancer	20016488	CNVD
Metanephric adenoma	20802469	CNVD
Breast cancer	21858162	CNVD
Hirschsprung''s Disease	21712996	CNVD
Cancer	21183584	CNVD
Oral squamous cell carcinoma	17134496	CNVD
Renal cell carcinoma	18194544	CNVD
Invasive pancreatic ductal carcinoma	16982739	CNVD
Myelofibrosis	22110671	CNVD
Breast cancer	21364760	CNVD
Acute lymphoblastic leukemia	21098271	CNVD
Glioblastoma multiforme	21390271	CNVD
Pancreatic cancer	17952125	CNVD
Breast cancer	22522925	CNVD

Chromatin state (count:136 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:46146400-46146800	Enhancers	Breast Myoepithelial Primary Cells	Breast
2	chr14:46146800-46147000	Enhancers	NHEK	skin
3	chr14:46146800-46149800	Weak transcription	Breast Myoepithelial Primary Cells	Breast
4	chr14:46147200-46148200	Weak transcription	NHEK	skin
5	chr14:46147600-46151200	Enhancers	Muscle Satellite Cultured Cells	--
6	chr14:46148000-46148600	Enhancers	Foreskin Melanocyte Primary Cells skin01	Skin
7	chr14:46148000-46150600	Enhancers	HSMM	muscle
8	chr14:46148200-46148400	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
9	chr14:46148200-46148400	Enhancers	HSMMtube	muscle
10	chr14:46148200-46149000	Enhancers	NHEK	skin
11	chr14:46148200-46149600	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
12	chr14:46148200-46150400	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
13	chr14:46148200-46150600	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
14	chr14:46148200-46150800	Enhancers	HUVEC	blood vessel
15	chr14:46148200-46152200	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
16	chr14:46148600-46148800	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
17	chr14:46148600-46148800	Enhancers	NHLF	lung
18	chr14:46148600-46149000	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
19	chr14:46148600-46149200	Enhancers	HMEC	breast
20	chr14:46148600-46149400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
21	chr14:46148600-46150400	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
22	chr14:46148800-46149400	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
23	chr14:46148800-46149400	Enhancers	Rectal Smooth Muscle	rectum
24	chr14:46148800-46149600	Enhancers	Colon Smooth Muscle	Colon
25	chr14:46148800-46149800	Weak transcription	NHLF	lung
26	chr14:46148800-46150400	Enhancers	NH-A	brain
27	chr14:46148800-46150600	Enhancers	Osteobl	bone
28	chr14:46149000-46149200	Flanking Active TSS	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
29	chr14:46149000-46149200	Flanking Active TSS	NHEK	skin
30	chr14:46149000-46149400	Enhancers	ES-I3 Cell Line	embryonic stem cell
31	chr14:46149000-46149400	Enhancers	Fetal Adrenal Gland	Adrenal Gland
32	chr14:46149000-46150000	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
33	chr14:46149000-46150600	Enhancers	Foreskin Fibroblast Primary Cells skin02	Skin
34	chr14:46149200-46149400	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
35	chr14:46149200-46149400	Enhancers	NHEK	skin
36	chr14:46149200-46150200	Weak transcription	HMEC	breast
37	chr14:46149400-46149600	Flanking Active TSS	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
38	chr14:46149400-46149600	Flanking Active TSS	NHEK	skin
39	chr14:46149400-46149800	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
40	chr14:46149400-46149800	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
41	chr14:46149400-46150200	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
42	chr14:46149400-46150400	Weak transcription	Rectal Smooth Muscle	rectum
43	chr14:46149600-46150600	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
44	chr14:46149600-46150600	Enhancers	NHEK	skin
45	chr14:46149800-46150000	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
46	chr14:46149800-46150400	Enhancers	Breast Myoepithelial Primary Cells	Breast
47	chr14:46149800-46150400	Enhancers	Fetal Adrenal Gland	Adrenal Gland
48	chr14:46149800-46150600	Enhancers	NHLF	lung
49	chr14:46150000-46150400	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
50	chr14:46150000-46150400	Enhancers	HSMMtube	muscle

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