Variant report

Variant	esv2762193
Chromosome Location	chr1:153673674-153693248
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ARID3A	chr1:153681205-153681214	K562	blood:	n/a	n/a
2	ATF1	chr1:153681171-153681275	K562	blood:	n/a	n/a
3	ATF3	chr1:153688756-153688956	K562	blood:	n/a	n/a
4	BACH1	chr1:153681860-153681933	K562	blood:	n/a	n/a
5	BATF	chr1:153689840-153690071	GM12878	blood:	n/a	chr1:153689961-153689972
6	BATF	chr1:153689854-153690094	GM12878	blood:	n/a	chr1:153689961-153689972
7	BRCA1	chr1:153680550-153681789	Hela-S3	cervix:	n/a	n/a
8	CEBPB	chr1:153681144-153681400	MCF-7	breast:	n/a	n/a
9	CEBPB	chr1:153673509-153673790	MCF-7	breast:	n/a	chr1:153673657-153673668 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673667
10	CEBPB	chr1:153680514-153682077	Hela-S3	cervix:	n/a	chr1:153681117-153681128
11	CEBPB	chr1:153692978-153693071	K562	blood:	n/a	n/a
12	CEBPB	chr1:153681120-153681425	A549	lung:	n/a	n/a
13	CEBPB	chr1:153692919-153693149	H1-hESC	embryonic stem cell:	n/a	n/a
14	CEBPB	chr1:153681117-153681359	IMR90	lung:	n/a	chr1:153681117-153681128
15	CEBPB	chr1:153681144-153681315	HepG2	liver:	n/a	n/a
16	CEBPB	chr1:153681111-153681312	K562	blood:	n/a	chr1:153681117-153681128
17	CEBPB	chr1:153673593-153673741	IMR90	lung:	n/a	chr1:153673657-153673668 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673667
18	CEBPB	chr1:153673656-153673846	HepG2	liver:	n/a	chr1:153673657-153673668 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673667
19	CEBPB	chr1:153681092-153681520	A549	lung:	n/a	chr1:153681117-153681128
20	CEBPB	chr1:153681783-153682028	A549	lung:	n/a	n/a
21	CEBPB	chr1:153673650-153673839	K562	blood:	n/a	chr1:153673657-153673668 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673669 chr1:153673656-153673667
22	CEBPB	chr1:153678102-153678322	K562	blood:	n/a	n/a
23	CEBPB	chr1:153678046-153678200	HepG2	liver:	n/a	n/a
24	CEBPB	chr1:153681177-153681352	K562	blood:	n/a	n/a
25	CHD2	chr1:153681038-153681352	Hela-S3	cervix:	n/a	n/a
26	CHD2	chr1:153680625-153680639	Hela-S3	cervix:	n/a	n/a
27	CREB1	chr1:153681011-153681297	A549	lung:	n/a	n/a
28	CTCF	chr1:153675482-153675525	GM13976	blood:	n/a	n/a
29	CTCF	chr1:153690120-153690270	MCF-7	breast:	n/a	n/a
30	CTCF	chr1:153683786-153683875	GM13976	blood:	n/a	n/a
31	CTCF	chr1:153680720-153680870	MCF-7	breast:	n/a	n/a
32	CTCF	chr1:153691062-153691140	MCF-7	breast:	n/a	n/a
33	CTCF	chr1:153691035-153691141	MCF-7	breast:	n/a	n/a
34	CUX1	chr1:153682413-153682580	K562	blood:	n/a	n/a
35	EBF1	chr1:153678880-153679087	GM12878	blood:	n/a	n/a
36	EP300	chr1:153680520-153681426	Hela-S3	cervix:	n/a	n/a
37	FOS	chr1:153678052-153678309	MCF10A-Er-Src	breast:	n/a	n/a
38	FOS	chr1:153681077-153681426	MCF10A-Er-Src	breast:	n/a	n/a
39	FOS	chr1:153678068-153678329	MCF10A-Er-Src	breast:	n/a	n/a
40	FOS	chr1:153688869-153688924	MCF10A-Er-Src	breast:	n/a	n/a
41	FOS	chr1:153681062-153681430	MCF10A-Er-Src	breast:	n/a	n/a
42	FOS	chr1:153678113-153678312	MCF10A-Er-Src	breast:	n/a	n/a
43	FOS	chr1:153681080-153681424	MCF10A-Er-Src	breast:	n/a	n/a
44	FOS	chr1:153688743-153688940	MCF10A-Er-Src	breast:	n/a	n/a
45	FOS	chr1:153681061-153681426	MCF10A-Er-Src	breast:	n/a	n/a
46	FOS	chr1:153688869-153688954	MCF10A-Er-Src	breast:	n/a	n/a
47	FOS	chr1:153691790-153691852	MCF10A-Er-Src	breast:	n/a	n/a
48	FOS	chr1:153691754-153691870	MCF10A-Er-Src	breast:	n/a	n/a
49	FOSL2	chr1:153680961-153681446	A549	lung:	n/a	n/a
50	FOSL2	chr1:153680966-153681425	MCF-7	breast:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr1:153668994..153671784-chr1:153687110..153689814,2	K562	blood:
2	chr1:153679930..153682838-chr1:153699485..153702427,4	MCF-7	breast:
3	chr1:153642439..153645279-chr1:153680616..153682934,3	MCF-7	breast:
4	chr1:153677967..153682113-chr1:153686591..153688988,3	MCF-7	breast:
5	chr1:153669943..153671545-chr1:153672210..153674806,2	K562	blood:
6	chr1:153677967..153682113-chr1:153686591..153688988,3	MCF-7	breast:
7	chr1:153669864..153672115-chr1:153679120..153682442,3	MCF-7	breast:
8	chr1:153672193..153673896-chr1:153690766..153693363,2	MCF-7	breast:
9	chr1:153676052..153678273-chr1:153679043..153680683,2	MCF-7	breast:
10	chr1:153679139..153682305-chr1:153689935..153694453,5	MCF-7	breast:
11	chr1:153679572..153681343-chr1:153699326..153701642,2	MCF-7	breast:
12	chr1:153681393..153682324-chr16:2264390..2265358,2	Hela-S3	cervix:
13	chr1:153679721..153682255-chr1:153699545..153702126,2	K562	blood:
14	chr1:153679034..153681144-chr1:153743976..153746673,2	MCF-7	breast:
15	chr1:153685180..153687511-chr1:153746756..153749223,2	MCF-7	breast:
16	chr1:153683195..153686007-chr1:153700603..153703489,3	MCF-7	breast:
17	chr1:153690798..153692537-chr1:153698848..153701656,2	K562	blood:
18	chr1:153650435..153653664-chr1:153678187..153682235,3	MCF-7	breast:
19	chr1:153680755..153683313-chr1:153700229..153702126,2	K562	blood:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-ILF2-1	chr1:153689779-153690298	NONHSAT006541
2	lnc-ILF2-1	chr1:153690592-153690823	NONHSAT006541
3	lnc-NPR1-1	chr1:153676564-153676859	NONHSAT006540

Variant related genes	Relation type
ENSG00000235015	TF binding region
RN7SL372P	TF binding region
ENSG00000235015	chromatin interactions
ENSG00000242565	chromatin interactions
ENSG00000169418	chromatin interactions
ENSG00000143621	chromatin interactions
ENSG00000143624	chromatin interactions
ENSG00000143554	chromatin interactions
ENSG00000184207	chromatin interactions

Extended variants
information (count: 732 )
Associated
traits (count: 115 )

Variant overlapped rSNPs/rCNVs (count:732 , 50 per page) page: 1 2 3 4 5 6 7 ... 15

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs564604837	chr1:153673675-153673676	Weak transcription Enhancers	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
2	rs193186733	chr1:153673687-153673688	Weak transcription Enhancers	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
3	rs73011738	chr1:153673701-153673702	Weak transcription Enhancers	TF binding region Chromatin interactive region	2 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
4	rs555653629	chr1:153673735-153673736	Weak transcription Enhancers	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
5	rs112591695	chr1:153673739-153673740	Weak transcription Enhancers	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
6	rs184725966	chr1:153673765-153673766	Weak transcription Enhancers	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
7	rs545758782	chr1:153673828-153673829	Weak transcription	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
8	rs71626781	chr1:153673833-153673834	Weak transcription	TF binding region Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
9	rs113542668	chr1:153673866-153673867	Weak transcription	Chromatin interactive region	1 gene(s)	Overlapped CNVs	n/a
10	rs557781416	chr1:153673925-153673926	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
11	rs576132014	chr1:153673940-153673941	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
12	rs112865942	chr1:153673988-153673989	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
13	rs113265790	chr1:153674017-153674018	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
14	rs28576254	chr1:153674022-153674023	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
15	rs561729571	chr1:153674037-153674038	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
16	rs573675232	chr1:153674054-153674055	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
17	rs578223956	chr1:153674062-153674063	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
18	rs545449678	chr1:153674067-153674068	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
19	rs533245905	chr1:153674070-153674071	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
20	rs143622268	chr1:153674077-153674078	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
21	rs562505555	chr1:153674122-153674123	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
22	rs563327704	chr1:153674188-153674189	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
23	rs368794939	chr1:153674207-153674208	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
24	rs9660002	chr1:153674211-153674212	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
25	rs188458849	chr1:153674252-153674253	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
26	rs567706722	chr1:153674260-153674261	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
27	rs534821006	chr1:153674274-153674275	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
28	rs536478653	chr1:153674294-153674295	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
29	rs547164591	chr1:153674314-153674315	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
30	rs571791750	chr1:153674316-153674317	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
31	rs140688170	chr1:153674317-153674318	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
32	rs539314821	chr1:153674319-153674320	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
33	rs557719967	chr1:153674350-153674351	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
34	rs138908762	chr1:153674391-153674392	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
35	rs76813726	chr1:153674457-153674458	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
36	rs537014526	chr1:153674463-153674464	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
37	rs372722126	chr1:153674464-153674465	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
38	rs142927186	chr1:153674481-153674482	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
39	rs7518794	chr1:153674505-153674506	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
40	rs7547783	chr1:153674546-153674547	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
41	rs7547790	chr1:153674563-153674564	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
42	rs192724317	chr1:153674577-153674578	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
43	rs60232551	chr1:153674582-153674583	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
44	rs548295623	chr1:153674595-153674596	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
45	rs149363979	chr1:153674602-153674603	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
46	rs4845565	chr1:153674622-153674623	Weak transcription Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
47	rs12239019	chr1:153674623-153674624	Weak transcription Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
48	rs34607389	chr1:153674655-153674656	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
49	rs530719507	chr1:153674662-153674663	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
50	rs548927759	chr1:153674663-153674664	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:115)

Disease	PMID	Source
Breast cancer	17603634	CNVD
Esophageal squamous carcinoma	21637470	CNVD
HIV/AIDS	22032296	CNVD
Schizophrenia	19415332	CNVD
Thoracic aortic aneurysm	21092924	CNVD
Autism	22495311	CNVD
Ewing''s sarcoma	21437220	CNVD
Liposarcoma	21253554	CNVD
Non-small cell lung cancer	21385341	CNVD
Diffuse large b-cell lymphoma	18287131	CNVD
Hepatocellular carcinoma	16750200	CNVD
Burkitt''s lymphoma	18698080	CNVD
Melanoma	18172304	CNVD
Breast cancer	20409316	CNVD
Splenic marginal zone lymphoma	21957467	CNVD
Breast cancer	17393978	CNVD
Cervical cancer	21062161	CNVD
Glioblastoma multiforme	21080181	CNVD
Cancer	21183584	CNVD
Multiple myeloma	16461302	CNVD
Lung cancer	18438408	CNVD
Rett syndrome	21593744	CNVD
Intellectual disability	22102821	CNVD
Cancer	20164919	CNVD
Medulloblastoma	21979893	CNVD
Systemic lupus erythematosus	21956041	CNVD
Non-syndromic sensorineural hearing loss	15273396	CNVD
Acute lymphoblastic leukemia	17443227	CNVD
Wilms tumour	21544195	CNVD
Breast cancer	17133270	CNVD
Esophageal squamous carcinoma	18350619	CNVD
Non-small cell lung cancer	21829676	CNVD
Carcinoma ex pleomorphic adenoma	18828159	CNVD
Non-small cell lung cancer	21044232	CNVD
Cervical cancer	21063398	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Astrocytoma	17387387	CNVD
Breast cancer	20632083	CNVD
Endometrial cancer	22040021	CNVD
Gastrointestinal stromal cancer	20470368	CNVD
Glioblastoma multiforme	19960244	CNVD
Hepatocellular carcinoma	22174799	CNVD
Medulloblastoma	21292688	CNVD
Phyllodes tumor	17334353	CNVD
Breast cancer	21264507	CNVD
Multiple myeloma	21628407	CNVD
Cancer	16751803	CNVD
Prostate cancer	16705090	CNVD
Neuroblastoma	19435921	CNVD
Breast cancer	17850661	CNVD
Breast cancer	16461572	CNVD
Intracranial tumor	16823260	CNVD
Medulloblastoma	18056178	CNVD
Monoclonal gammopathy of undetermined significance	17077331	CNVD
Primary mediastinal b-cell lymphoma	17728785	CNVD
Colorectal cancer	16272173	CNVD
Acute lymphoblastic leukemia	21098271	CNVD
Neuroblastoma	21899760	CNVD
Breast cancer	17899364	CNVD
Bladder cancer	19088036	CNVD
Ovarian neoplasms	16753589	CNVD
Glioblastoma multiforme	17002787	CNVD
Breast cancer	21858162	CNVD
Retinoblastoma	19183342	CNVD
Invasive pancreatic ductal carcinoma	16982739	CNVD
Acute lymphoblastic leukemia	21980252	CNVD
Breast cancer	16608533	CNVD
Ewing''s sarcoma	22429812	CNVD
Acute promyelocytic leukemia	19109227	CNVD
Ewing''s sarcoma	17952124	CNVD
Osteosarcoma	17242211	CNVD
Ovarian cancer	17242211	CNVD
Ovine squamous-cell carcinoma	17599052	CNVD
Schizophrenia	18990708	CNVD
Sudden cardiac death	19188705	CNVD
Plasma-cell dyscrasia	16705089	CNVD
Myeloma	17024118	CNVD
Cancer	17060936	CNVD
Multiple myeloma	16616336	CNVD
Type 2 diabetes	19141583	CNVD
Chordoma	18071362	CNVD
Hepatocellular carcinoma	18803288	CNVD
Basal cell lymphoma	16317097	CNVD
Diffuse large b-cell lymphoma	16317097	CNVD
Breast cancer	17001317	CNVD
Urothelial carcinoma	21177765	CNVD
Burkitt''s lymphoma	19759907	CNVD
Acute myeloid leukemia	21251322	CNVD
Multiple myeloma	17550852	CNVD
Prostate cancer	18632612	CNVD
Breast cancer	21509527	CNVD
Bladder cancer	21909424	CNVD
Acute myeloid leukemia	20729466	CNVD
Hodgkin''s lymphoma	17606441	CNVD
small cell lung cancer	20016488	CNVD
Ovarian clear cell carcinoma	21343371	CNVD
Testicular germ cell tumor	18059402	CNVD
Trisomy 5 syndrome	21098271	CNVD
Ependymoma	18628472	CNVD
Leukemia	18628472	CNVD
Gastrointestinal cancer	16790693	CNVD
Esophageal adenocarcinoma	18519675	CNVD
Chronic lymphocytic leukemia	22228453	CNVD
Glioblastoma multiforme	21138945	CNVD
low-grade B-cell lymphoma tumor	18367492	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Acute lymphoblastic leukemia	18458336	CNVD
Breast cancer	21611746	CNVD
Acute lymphoblastic leukemia	21339820	CNVD
Myelofibrosis	22110671	CNVD
Follicular lymphoma	20505157	CNVD
Liver carcinoma	19366792	CNVD
Neuroblastoma	18923191	CNVD
Schizophrenia	23813976	CNVD
Breast cancer	22522925	CNVD

Chromatin state (count:45 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr1:153671600-153678200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
2	chr1:153672000-153674800	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
3	chr1:153672000-153675200	Weak transcription	Right Atrium	heart
4	chr1:153672200-153673800	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
5	chr1:153672600-153674600	Weak transcription	K562	blood
6	chr1:153674600-153675200	Enhancers	K562	blood
7	chr1:153674800-153675000	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
8	chr1:153675000-153679400	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
9	chr1:153675200-153680600	Weak transcription	K562	blood
10	chr1:153678000-153678200	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
11	chr1:153678200-153680600	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
12	chr1:153679200-153679800	Enhancers	Hela-S3	cervix
13	chr1:153679800-153680200	Weak transcription	Hela-S3	cervix
14	chr1:153680200-153680600	Enhancers	Hela-S3	cervix
15	chr1:153680400-153681000	Enhancers	Breast Myoepithelial Primary Cells	Breast
16	chr1:153680400-153681600	Enhancers	Placenta	Placenta
17	chr1:153680600-153681000	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
18	chr1:153680600-153681000	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
19	chr1:153680600-153681000	Enhancers	Adipose Nuclei	Adipose
20	chr1:153680600-153681000	Flanking Active TSS	Hela-S3	cervix
21	chr1:153680600-153681200	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
22	chr1:153680600-153681200	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
23	chr1:153680600-153681200	Enhancers	HepG2	liver
24	chr1:153680600-153682000	Enhancers	A549	lung
25	chr1:153680600-153682000	Enhancers	K562	blood
26	chr1:153681000-153681200	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
27	chr1:153681000-153681200	Bivalent Enhancer	IMR90 fetal lung fibroblasts Cell Line	lung
28	chr1:153681000-153681800	Active TSS	Hela-S3	cervix
29	chr1:153681000-153683200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
30	chr1:153681600-153682000	Flanking Active TSS	Placenta	Placenta
31	chr1:153681800-153682000	Flanking Active TSS	Hela-S3	cervix
32	chr1:153682000-153682400	Enhancers	Hela-S3	cervix
33	chr1:153682000-153683400	Weak transcription	A549	lung
34	chr1:153682400-153683200	Weak transcription	Hela-S3	cervix
35	chr1:153683200-153683400	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
36	chr1:153683200-153683600	Enhancers	Hela-S3	cervix
37	chr1:153683400-153683800	Active TSS	Foreskin Fibroblast Primary Cells skin02	Skin
38	chr1:153683400-153683800	Flanking Active TSS	Foreskin Keratinocyte Primary Cells skin02	Skin
39	chr1:153683400-153683800	Enhancers	A549	lung
40	chr1:153683400-153683800	Active TSS	NHEK	skin
41	chr1:153687000-153687200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
42	chr1:153687200-153687400	Enhancers	ES-I3 Cell Line	embryonic stem cell
43	chr1:153687400-153699800	Weak transcription	ES-I3 Cell Line	embryonic stem cell
44	chr1:153690200-153690400	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
45	chr1:153690400-153699000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell

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