Variant report

Variant	esv3434490
Chromosome Location	chr10:89673470-89673933
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:89620299..89623441-chr10:89672450..89675807,5	MCF-7	breast:
2	chr10:89671146..89673722-chr10:89679466..89681540,2	MCF-7	breast:
3	chr10:89673644..89678140-chr10:89679296..89683460,5	K562	blood:

Variant related genes	Relation type
ENSG00000227268	chromatin interactions
ENSG00000171862	chromatin interactions

Extended variants
information (count: 19 )
Associated
traits (count: 120 )

Variant overlapped rSNPs/rCNVs (count:19 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs535469783	chr10:89673491-89673492	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
2	rs557395396	chr10:89673512-89673513	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
3	rs74562518	chr10:89673554-89673555	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
4	rs1234225	chr10:89673569-89673570	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
5	rs192081057	chr10:89673576-89673577	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
6	rs78938505	chr10:89673612-89673613	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
7	rs540494700	chr10:89673665-89673666	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
8	rs552099621	chr10:89673675-89673676	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
9	rs368181306	chr10:89673691-89673692	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
10	rs548475618	chr10:89673712-89673713	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
11	rs372411529	chr10:89673717-89673718	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
12	rs568687556	chr10:89673739-89673740	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
13	rs562537471	chr10:89673753-89673754	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
14	rs78068525	chr10:89673786-89673787	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
15	rs551499434	chr10:89673789-89673790	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
16	rs570281946	chr10:89673795-89673796	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
17	rs570908886	chr10:89673858-89673859	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
18	rs534028204	chr10:89673871-89673872	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a
19	rs537749318	chr10:89673921-89673922	Weak transcription ZNF genes & repeats Strong transcription Genic enhancers	Chromatin interactive region	2 gene(s)	Overlapped CNVs	n/a

Variant related diseases (count:120)

Disease	PMID	Source
Gastric cancer	17908304	CNVD
Chordoma	21602918	CNVD
Ewing''s sarcoma	21437220	CNVD
Glioblastoma multiforme	21080181	CNVD
Medulloblastoma	21979893	CNVD
Melanoma	18172304	CNVD
Pleomorphic xanthoastrocytoma	20730472	CNVD
Ewing''s sarcoma	17952124	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Thoracic aortic aneurysm	21092924	CNVD
Hodgkin''s lymphoma	17606441	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Acute lymphoblastic leukemia	20724749	CNVD
Autism	22495311	CNVD
Prostate cancer	18632612	CNVD
Cockayne syndrome	18421352	CNVD
Glioblastoma	16823260	CNVD
Medulloblastoma	16968546	CNVD
Neuroblastoma	17533364	CNVD
Squamous cell cancer	21044232	CNVD
Glioma	21971842	CNVD
Cancer	21637783	CNVD
Non-small cell lung cancer	21044232	CNVD
Non-syndromic sensorineural hearing loss	18471307	CNVD
Colorectal cancer	20709793	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	21264507	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Liposarcoma	21253554	CNVD
Oligodendroglial tumors	17285580	CNVD
Lung cancer	18438408	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
Usher syndrome	20538994	CNVD
Medulloblastoma	16783165	CNVD
Breast cancer	21785460	CNVD
Acute myeloid leukemia	20729466	CNVD
Prostate cancer	16573809	CNVD
Paraganglioma	17535989	CNVD
Submicroscopic aberration syndrome	21292638	CNVD
Gastrointestinal stromal cancer	17535989	CNVD
Pancreatic endocrine tumor	17639061	CNVD
Pulmonary chondroma	17535989	CNVD
Acute lymphoblastic leukemia	22237106	CNVD
Colorectal cancer	18645599	CNVD
Polyposis syndrome	18645599	CNVD
Prostate cancer	17245344	CNVD
Glioblastoma multiforme	17369134	CNVD
Glioblastoma multiforme	21750150	CNVD
Breast cancer	22032731	CNVD
Ovarian cancer	20844748	CNVD
Glioblastoma multiforme	17002787	CNVD
Astrocytoma	17387387	CNVD
Breast cancer	17603634	CNVD
Glioblastoma multiforme	17387387	CNVD
low-grade B-cell lymphoma tumor	18367492	CNVD
Breast cancer	21364760	CNVD
T-cell acute lymphoblastic leukemia	19406988	CNVD
High-grade prostatic intraepithelial neoplasia	16573809	CNVD
Acute lymphoblastic leukemia	21339820	CNVD
Wilms tumour	21544195	CNVD
Glioblastoma multiforme	21569311	CNVD
Cancer	20164919	CNVD
Melanoma	17363583	CNVD
small cell lung cancer	20016488	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Urothelial carcinoma	21177765	CNVD
Cancer	20164920	CNVD
Esophageal adenocarcinoma	18519675	CNVD
Colorectal cancer	19359472	CNVD
Neurocytoma	17123091	CNVD
Prostate cancer	16461572	CNVD
Basal-like breast cancer	18066063	CNVD
Effusion lymphoma	18079361	CNVD
Glioblastoma multiforme	19115005	CNVD
Prostate cancer	21147910	CNVD
Lung cancer	21911935	CNVD
Myelofibrosis	22110671	CNVD
Prostate cancer	21088497	CNVD
Breast cancer	22048815	CNVD
Cutaneous T-cell lymphoma	21881587	CNVD
Glioblastoma multiforme	22291905	CNVD
Glioblastoma multiforme	19435819	CNVD
Glioblastoma multiforme	22286061	CNVD
Intracranial ependymoma	16609018	CNVD
Breast cancer	16397240	CNVD
Chronic lymphocytic leukemia	21049055	CNVD
Cervical cancer	21062161	CNVD
Non-small cell lung cancer	21829676	CNVD
Melanoma	24453001	CNVD
Breast cancer	16608533	CNVD
Melanoma	20877625	CNVD
Non-syndromic sensorineural hearing loss	20020426	CNVD
Ovarian cancer	22174824	CNVD
Breast cancer	22065749	CNVD
Cancer	22000013	CNVD
Colon cancer	22065749	CNVD
Endometrial cancer	22065749	CNVD
Lung cancer	20668451	CNVD
Breast cancer	17634833	CNVD
Cancer	20215515	CNVD
Glioblastoma multiforme	21727940	CNVD
Prostate cancer	19363497	CNVD
Prostate cancer	17700571	CNVD
Breast cancer	20668451	CNVD
Cancer	20668451	CNVD
Ovarian cancer	20668451	CNVD
Pancreas cancer	20668451	CNVD
Prostate cancer	20668451	CNVD
Cutaneous malignant melanoma	18794153	CNVD
Ovarian cancer	21781307	CNVD
T-cell lymphomas	22341440	CNVD
Breast cancer	22522925	CNVD
Pancreatic cancer	17952125	CNVD
Autism	20964600	CNVD
Endometrial cancer	19261849	CNVD
Central neurocytomas	17123091	CNVD
Malignant melanoma	17260012	CNVD
Congenital anomalies of the kidney and urinary tract	18852474	CNVD
Acute lymphoblastic leukemia	19100363	CNVD
Lung adenocarcinoma	17982442	CNVD

Chromatin state (count:127 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:89633400-89675800	Weak transcription	Small Intestine	intestine
2	chr10:89647000-89711200	Weak transcription	Stomach Smooth Muscle	stomach
3	chr10:89647200-89675400	Weak transcription	Muscle Satellite Cultured Cells	--
4	chr10:89648000-89683000	Weak transcription	Rectal Smooth Muscle	rectum
5	chr10:89648200-89674400	Weak transcription	Right Ventricle	heart
6	chr10:89653200-89675200	Weak transcription	NHLF	lung
7	chr10:89656000-89675000	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
8	chr10:89656600-89675800	Weak transcription	Osteobl	bone
9	chr10:89658400-89676400	Weak transcription	Placenta Amnion	Placenta Amnion
10	chr10:89663400-89675200	Weak transcription	iPS-18 Cell Line	embryonic stem cell
11	chr10:89663400-89675200	Weak transcription	Gastric	stomach
12	chr10:89663600-89675200	Weak transcription	Pancreas	Pancrea
13	chr10:89663600-89686400	Weak transcription	H9 Cell Line	embryonic stem cell
14	chr10:89663600-89687400	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
15	chr10:89663800-89675200	Weak transcription	Skeletal Muscle Female	skeletal muscle
16	chr10:89663800-89725400	Weak transcription	Colonic Mucosa	Colon
17	chr10:89664000-89674200	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
18	chr10:89664000-89674800	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
19	chr10:89664000-89675000	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
20	chr10:89664000-89675200	Strong transcription	Fetal Thymus	thymus
21	chr10:89664000-89675200	Weak transcription	Left Ventricle	heart
22	chr10:89664000-89675200	Weak transcription	Lung	lung
23	chr10:89664000-89681800	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
24	chr10:89664200-89674200	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
25	chr10:89664200-89674400	Weak transcription	iPS-20b Cell Line	embryonic stem cell
26	chr10:89664200-89675200	Weak transcription	HUES48 Cell Line	embryonic stem cell
27	chr10:89664600-89675200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
28	chr10:89664800-89675000	Weak transcription	H1 Cell Line	embryonic stem cell
29	chr10:89664800-89675000	Weak transcription	Sigmoid Colon	Sigmoid Colon
30	chr10:89664800-89675200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
31	chr10:89664800-89675200	Weak transcription	HUES6 Cell Line	embryonic stem cell
32	chr10:89664800-89676400	Weak transcription	iPS-15b Cell Line	embryonic stem cell
33	chr10:89665200-89675200	Weak transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
34	chr10:89665200-89675400	Weak transcription	NH-A	brain
35	chr10:89665600-89675200	Weak transcription	Esophagus	oesophagus
36	chr10:89666000-89712400	Weak transcription	Fetal Brain Male	brain
37	chr10:89666600-89675600	ZNF genes & repeats	GM12878-XiMat	blood
38	chr10:89666600-89682800	Weak transcription	Placenta	Placenta
39	chr10:89667000-89675400	Weak transcription	Fetal Heart	heart
40	chr10:89668000-89675200	Weak transcription	HMEC	breast
41	chr10:89668400-89675200	Weak transcription	Psoas Muscle	Psoas
42	chr10:89670000-89674000	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
43	chr10:89670000-89674600	ZNF genes & repeats	Primary hematopoietic stem cells G-CSF-mobilized Male	--
44	chr10:89670200-89674600	ZNF genes & repeats	Primary hematopoietic stem cells	blood
45	chr10:89670400-89674800	ZNF genes & repeats	Primary B cells from peripheral blood	blood
46	chr10:89670400-89675000	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
47	chr10:89670800-89674200	ZNF genes & repeats	Primary T cells from cord blood	blood
48	chr10:89671200-89674600	ZNF genes & repeats	Pancreatic Islets	Pancreatic Islet
49	chr10:89671400-89673600	ZNF genes & repeats	Adipose Nuclei	Adipose
50	chr10:89671400-89674000	ZNF genes & repeats	Primary T helper cells fromperipheralblood	blood

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links