Variant report

Variant	nsv455678
Chromosome Location	chr12:85698817-85785109
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ARID3A	chr12:85704287-85704562	HepG2	liver:	n/a	n/a
2	BRCA1	chr12:85725088-85725176	Hela-S3	cervix:	n/a	n/a
3	BRCA1	chr12:85763290-85763939	Hela-S3	cervix:	n/a	n/a
4	CEBPB	chr12:85722482-85722750	H1-hESC	embryonic stem cell:	n/a	chr12:85722609-85722620 chr12:85722608-85722621 chr12:85722608-85722619 chr12:85722610-85722619
5	CEBPB	chr12:85718358-85718597	HepG2	liver:	n/a	n/a
6	CEBPB	chr12:85766849-85767176	IMR90	lung:	n/a	n/a
7	CEBPB	chr12:85766861-85767198	HepG2	liver:	n/a	n/a
8	CEBPB	chr12:85722468-85722799	HepG2	liver:	n/a	chr12:85722609-85722620 chr12:85722608-85722621 chr12:85722608-85722619 chr12:85722735-85722752 chr12:85722610-85722619
9	CEBPB	chr12:85722457-85722786	A549	lung:	n/a	chr12:85722609-85722620 chr12:85722608-85722621 chr12:85722608-85722619 chr12:85722735-85722752 chr12:85722610-85722619
10	CEBPB	chr12:85722452-85722751	K562	blood:	n/a	chr12:85722609-85722620 chr12:85722608-85722621 chr12:85722608-85722619 chr12:85722610-85722619
11	CEBPB	chr12:85722443-85722800	IMR90	lung:	n/a	chr12:85722609-85722620 chr12:85722608-85722621 chr12:85722608-85722619 chr12:85722735-85722752 chr12:85722610-85722619
12	CEBPB	chr12:85776529-85776577	A549	lung:	n/a	n/a
13	CEBPB	chr12:85766898-85767160	Hela-S3	cervix:	n/a	n/a
14	CEBPB	chr12:85766923-85767123	H1-hESC	embryonic stem cell:	n/a	n/a
15	CEBPB	chr12:85766874-85767185	A549	lung:	n/a	n/a
16	CHD2	chr12:85759437-85759734	K562	blood:	n/a	n/a
17	CTCF	chr12:85704434-85704538	GM13977	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
18	CTCF	chr12:85704420-85704570	BJ	skin:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
19	CTCF	chr12:85704416-85704420	K562	blood:	n/a	n/a
20	CTCF	chr12:85704360-85704510	GM12865	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
21	CTCF	chr12:85704420-85704570	GM12873	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
22	CTCF	chr12:85704540-85704690	MCF-7	breast:	n/a	n/a
23	CTCF	chr12:85716585-85716726	Lung_OC	lung:	n/a	chr12:85716616-85716637
24	CTCF	chr12:85704720-85704870	BJ	skin:	n/a	n/a
25	CTCF	chr12:85704399-85704571	GM12878	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
26	CTCF	chr12:85703180-85703330	HPF	lung:	n/a	n/a
27	CTCF	chr12:85763000-85763150	HRE	kidney:	n/a	n/a
28	CTCF	chr12:85703880-85704030	HCM	heart:	n/a	n/a
29	CTCF	chr12:85704340-85704490	GM12874	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
30	CTCF	chr12:85704800-85704950	HRPEpiC	eye:	n/a	n/a
31	CTCF	chr12:85704480-85704630	RPTEC	kidney:	n/a	n/a
32	CTCF	chr12:85704320-85704470	A549	lung:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
33	CTCF	chr12:85704400-85704550	HPF	lung:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
34	CTCF	chr12:85704520-85704670	HCPEpiC	choroid plexus:	n/a	n/a
35	CTCF	chr12:85704520-85704670	HFF-Myc	foreskin:	n/a	n/a
36	CTCF	chr12:85704560-85704710	GM12866	blood:	n/a	n/a
37	CTCF	chr12:85716616-85716669	GM10248	blood:	n/a	chr12:85716616-85716637
38	CTCF	chr12:85704440-85704590	Caco-2	colon:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
39	CTCF	chr12:85704680-85704830	Caco-2	colon:	n/a	n/a
40	CTCF	chr12:85704360-85704510	HVMF	connective:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
41	CTCF	chr12:85704420-85704570	HCFaa	heart:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
42	CTCF	chr12:85704300-85704450	NHEK	skin:	n/a	n/a
43	CTCF	chr12:85704413-85704568	Hela-S3	cervix:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
44	CTCF	chr12:85704200-85704350	Caco-2	colon:	n/a	n/a
45	CTCF	chr12:85704360-85704510	HCPEpiC	choroid plexus:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
46	CTCF	chr12:85704423-85704543	GM10266	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
47	CTCF	chr12:85703980-85704130	HRPEpiC	eye:	n/a	n/a
48	CTCF	chr12:85704360-85704510	GM12878	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
49	CTCF	chr12:85704362-85704561	A549	lung:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464
50	CTCF	chr12:85704340-85704490	GM12871	blood:	n/a	chr12:85704441-85704459 chr12:85704444-85704457 chr12:85704442-85704458 chr12:85704443-85704464

No.	Distal block	Cell Line	Cell type
1	chr12:85704213..85704892-chr12:85788326..85789139,2	MCF-7	breast:
2	chr12:85735992..85737956-chr12:85742669..85744404,2	MCF-7	breast:
3	chr12:85767120..85767969-chr12:85795392..85796211,2	MCF-7	breast:
4	chr12:85704116..85704872-chr12:85842034..85842872,2	MCF-7	breast:
5	chr12:85745803..85747917-chr12:85750722..85752952,2	MCF-7	breast:
6	chr12:85735992..85737956-chr12:85742669..85744404,2	MCF-7	breast:
7	chr12:85745803..85747917-chr12:85750722..85752952,2	MCF-7	breast:
8	chr12:85703964..85704769-chr12:85788512..85789218,4	MCF-7	breast:
9	chr12:85713980..85716222-chr12:85718443..85721765,3	MCF-7	breast:
10	chr12:85712831..85715377-chr12:85729265..85730997,2	MCF-7	breast:
11	chr12:85712831..85715377-chr12:85729265..85730997,2	MCF-7	breast:
12	chr12:85693571..85695610-chr12:85696379..85699321,2	MCF-7	breast:
13	chr12:85713980..85716222-chr12:85718443..85721765,3	MCF-7	breast:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-ALX1-2	chr12:85759621-85759721	NONHSAT029750
2	lnc-ALX1-1	chr12:85733174-85733276	NONHSAT029749
3	lnc-ALX1-1	chr12:85712733-85712757	NONHSAT029749
4	lnc-ALX1-1	chr12:85712736-85712757	ENSG00000258815
5	lnc-ALX1-1	chr12:85736216-85736970	NONHSAT029749
6	lnc-ALX1-1	chr12:85711838-85711893	ENSG00000258815
7	lnc-ALX1-1	chr12:85736250-85736690	ENSG00000258815
8	lnc-ALX1-2	chr12:85763588-85763622	NONHSAT029751
9	lnc-ALX1-2	chr12:85763589-85763622	XLOC_009820

Variant related genes	Relation type
ENSG00000258815	TF binding region
KCNK1	miRNA target sites

Extended variants
information (count: 1561 )
Associated
traits (count: 69 )

Variant overlapped rSNPs/rCNVs (count:1561 , 50 per page) page: 1 2 3 4 5 6 7 ... 32

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs7295242	chr12:85698817-85698818	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
2	rs558509787	chr12:85698879-85698880	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
3	rs576863856	chr12:85698903-85698904	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
4	rs541122153	chr12:85698920-85698921	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
5	rs559593479	chr12:85698968-85698969	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
6	rs189849946	chr12:85699028-85699029	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
7	rs541673181	chr12:85699035-85699036	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
8	rs180754963	chr12:85699053-85699054	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
9	rs12824401	chr12:85699058-85699059	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
10	rs552533151	chr12:85699071-85699072	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
11	rs564062134	chr12:85699113-85699114	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
12	rs528139951	chr12:85699166-85699167	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
13	rs115714968	chr12:85699291-85699292	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
14	rs568073171	chr12:85699293-85699294	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
15	rs573669427	chr12:85699306-85699307	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
16	rs61930058	chr12:85699307-85699308	Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
17	rs186229973	chr12:85699316-85699317	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
18	rs546141857	chr12:85699317-85699318	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
19	rs553588930	chr12:85699329-85699330	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
20	rs191899855	chr12:85699331-85699332	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
21	rs201743499	chr12:85699352-85699353	Weak transcription	n/a	n/a	Overlapped CNVs	n/a
22	rs373496773	chr12:85699409-85699410	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
23	rs116217206	chr12:85699417-85699418	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
24	rs553396553	chr12:85699436-85699437	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
25	rs574857485	chr12:85699447-85699448	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
26	rs182090888	chr12:85699489-85699490	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
27	rs373391985	chr12:85699534-85699535	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
28	rs556861895	chr12:85699552-85699553	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
29	rs146223566	chr12:85699703-85699704	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
30	rs367764746	chr12:85699704-85699705	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
31	rs73165961	chr12:85699732-85699733	Enhancers Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
32	rs114755095	chr12:85699743-85699744	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
33	rs7316291	chr12:85699744-85699745	Enhancers Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
34	rs563771844	chr12:85699784-85699785	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
35	rs374271587	chr12:85699788-85699789	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
36	rs368134254	chr12:85699796-85699797	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
37	rs572292073	chr12:85699837-85699838	Flanking Active TSS Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
38	rs528052945	chr12:85699972-85699973	Flanking Active TSS Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
39	rs576072426	chr12:85699997-85699998	Flanking Active TSS Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
40	rs543572677	chr12:85700023-85700024	Bivalent Enhancer Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
41	rs539865340	chr12:85700064-85700065	Bivalent Enhancer Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
42	rs561796057	chr12:85700080-85700081	Bivalent Enhancer Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
43	rs540883335	chr12:85700117-85700118	Bivalent Enhancer Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
44	rs114065042	chr12:85700217-85700218	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
45	rs186067321	chr12:85700246-85700247	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
46	rs577191979	chr12:85700300-85700301	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
47	rs531010490	chr12:85700309-85700310	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
48	rs7980904	chr12:85700320-85700321	Enhancers Weak transcription	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
49	rs570823716	chr12:85700331-85700332	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a
50	rs190480008	chr12:85700399-85700400	Enhancers Weak transcription	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:69)

Disease	PMID	Source
Wilms tumour	21544195	CNVD
Esophageal cancer	21851588	CNVD
Lung cancer	20668451	CNVD
Breast cancer	20668451	CNVD
Cancer	20668451	CNVD
Ovarian cancer	20668451	CNVD
Pancreas cancer	20668451	CNVD
Prostate cancer	20668451	CNVD
Ewing''s sarcoma	21437220	CNVD
Testicular germ cell tumor	18059402	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Medulloblastoma	21979893	CNVD
Malaria	21533027	CNVD
Chronic lymphocytic leukemia	22228453	CNVD
Basal cell lymphoma	17053054	CNVD
Chronic lymphocytic leukemia	21670202	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Hodgkin''s lymphoma	17606441	CNVD
Autism	22495311	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Breast cancer	21949216	CNVD
Carcinoma ex pleomorphic adenoma	18828159	CNVD
Acute myeloid leukemia	16864856	CNVD
Cancer	21637783	CNVD
Glioblastoma multiforme	21080181	CNVD
Renal cell carcinoma	19461508	CNVD
Burkitt''s lymphoma	18698080	CNVD
Astrocytoma	17387387	CNVD
Breast cancer	21264507	CNVD
Glioblastoma multiforme	19960244	CNVD
Gastrointestinal stromal cancer	20470368	CNVD
Adenoid cystic carcinoma	17372589	CNVD
Lung cancer	18438408	CNVD
Breast cancer	17899364	CNVD
Cancer	16751803	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
small cell lung cancer	20016488	CNVD
Melanoma	18172304	CNVD
Glioblastoma multiforme	21390271	CNVD
Cancer	20164919	CNVD
Metanephric adenoma	20802469	CNVD
Acute myeloid leukemia	21251322	CNVD
Gastrointestinal stromal cancer	20877625	CNVD
abnormal development	18461090	CNVD
Prostate cancer	18632612	CNVD
High-grade prostatic intraepithelial neoplasia	16573809	CNVD
Myeloproliferative neoplasm	20015882	CNVD
Breast cancer	22032731	CNVD
Biliary cancer	20360734	CNVD
Breast cancer	20360734	CNVD
Coronary artery disease	20360734	CNVD
Crohn''s disease	20360734	CNVD
Hypertension	20360734	CNVD
Rheumatoid arthritis	20360734	CNVD
Type 1 diabetes	20360734	CNVD
Type 2 diabetes	20360734	CNVD
Malignant peripheral nerve sheath tumor	18522746	CNVD
Ovarian cancer	21720365	CNVD
Acute myeloid leukemia	20729466	CNVD
Myelofibrosis	22110671	CNVD
Colorectal cancer	16272173	CNVD
Acute lymphoblastic leukemia	21339820	CNVD
Renal cell carcinoma	18194544	CNVD
lymphocytic leukemia	21291569	CNVD
Breast cancer	21364760	CNVD
Bipolar disorder	19114987	CNVD
Non-syndromic sensorineural hearing loss	21293372	CNVD
Non-syndromic sensorineural hearing loss	18451855	CNVD
Non-syndromic sensorineural hearing loss	22037309	CNVD

Chromatin state (count:115 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr12:85698400-85699800	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
2	chr12:85698400-85700000	Weak transcription	Hela-S3	cervix
3	chr12:85698400-85703000	Weak transcription	A549	lung
4	chr12:85699400-85699800	Enhancers	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
5	chr12:85699400-85699800	Enhancers	iPS-15b Cell Line	embryonic stem cell
6	chr12:85699400-85700200	Enhancers	iPS-18 Cell Line	embryonic stem cell
7	chr12:85699400-85700400	Enhancers	HUES48 Cell Line	embryonic stem cell
8	chr12:85699400-85700400	Enhancers	HUES64 Cell Line	embryonic stem cell
9	chr12:85699400-85700400	Enhancers	ES-UCSF4 Cell Line	embryonic stem cell
10	chr12:85699800-85700000	Flanking Active TSS	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
11	chr12:85699800-85700000	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
12	chr12:85699800-85700200	Weak transcription	iPS-15b Cell Line	embryonic stem cell
13	chr12:85700000-85700200	Bivalent Enhancer	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
14	chr12:85700000-85702400	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
15	chr12:85700200-85700400	Enhancers	iPS-15b Cell Line	embryonic stem cell
16	chr12:85700400-85703000	Weak transcription	iPS-15b Cell Line	embryonic stem cell
17	chr12:85702000-85703200	Bivalent Enhancer	Fetal Lung	lung
18	chr12:85702200-85702400	Flanking Active TSS	Fetal Kidney	kidney
19	chr12:85702400-85702800	Enhancers	Fetal Kidney	kidney
20	chr12:85702400-85703200	Enhancers	Liver	Liver
21	chr12:85702400-85705200	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
22	chr12:85702600-85704000	Bivalent Enhancer	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
23	chr12:85702800-85703000	Weak transcription	Fetal Kidney	kidney
24	chr12:85703000-85703400	Enhancers	iPS-15b Cell Line	embryonic stem cell
25	chr12:85703000-85703600	Active TSS	A549	lung
26	chr12:85703000-85703800	Active TSS	Fetal Kidney	kidney
27	chr12:85703200-85704200	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
28	chr12:85705200-85716200	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
29	chr12:85711400-85711800	Enhancers	H1 Cell Line	embryonic stem cell
30	chr12:85711400-85712400	Active TSS	H9 Cell Line	embryonic stem cell
31	chr12:85711400-85712400	Active TSS	Placenta	Placenta
32	chr12:85711400-85712800	Active TSS	ES-I3 Cell Line	embryonic stem cell
33	chr12:85711800-85712200	Active TSS	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
34	chr12:85711800-85712200	Active TSS	HUES64 Cell Line	embryonic stem cell
35	chr12:85711800-85712200	Active TSS	iPS-15b Cell Line	embryonic stem cell
36	chr12:85711800-85712200	Active TSS	iPS DF 19.11 Cell Line	embryonic stem cell
37	chr12:85711800-85712400	Active TSS	H1 Cell Line	embryonic stem cell
38	chr12:85711800-85712400	Active TSS	iPS DF 6.9 Cell Line	embryonic stem cell
39	chr12:85711800-85712600	Active TSS	HUES48 Cell Line	embryonic stem cell
40	chr12:85711800-85713000	Active TSS	HUES6 Cell Line	embryonic stem cell
41	chr12:85712000-85712600	Active TSS	ES-WA7 Cell Line	embryonic stem cell
42	chr12:85712000-85712600	Active TSS	ES-UCSF4 Cell Line	embryonic stem cell
43	chr12:85712000-85712800	Active TSS	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
44	chr12:85712200-85712800	Flanking Active TSS	HUES64 Cell Line	embryonic stem cell
45	chr12:85712200-85712800	Flanking Active TSS	iPS-15b Cell Line	embryonic stem cell
46	chr12:85712600-85713000	Enhancers	H9 Cell Line	embryonic stem cell
47	chr12:85712800-85713000	Enhancers	iPS-15b Cell Line	embryonic stem cell
48	chr12:85712800-85719200	Weak transcription	HUES64 Cell Line	embryonic stem cell
49	chr12:85713000-85718200	Weak transcription	HUES6 Cell Line	embryonic stem cell
50	chr12:85716200-85716600	Enhancers	Fetal Lung	lung

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