Variant report

Variant	nsv544375
Chromosome Location	chr21:15777995-15882121
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:786)
CpG islands
(count:0)
Chromatin interactive
region (count:59)
LncRNA
region (count:3)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:786 , 50 per page) page: 1 2 3 4 5 6 7 ... 16

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ARID3A	chr21:15864283-15864314	K562	blood:	n/a	n/a
2	ARID3A	chr21:15879542-15879724	K562	blood:	n/a	n/a
3	ARID3A	chr21:15860343-15860727	K562	blood:	n/a	n/a
4	ARID3A	chr21:15824048-15825001	K562	blood:	n/a	n/a
5	ARID3A	chr21:15867403-15867905	K562	blood:	n/a	n/a
6	ARID3A	chr21:15826124-15827759	K562	blood:	n/a	chr21:15826133-15826149
7	ARID3A	chr21:15863823-15864036	K562	blood:	n/a	n/a
8	ATF1	chr21:15824148-15824786	K562	blood:	n/a	n/a
9	ATF1	chr21:15826468-15827188	K562	blood:	n/a	n/a
10	ATF2	chr21:15854334-15854968	GM12878	blood:	n/a	n/a
11	ATF2	chr21:15825022-15827615	GM12878	blood:	n/a	n/a
12	ATF2	chr21:15824774-15826281	GM12878	blood:	n/a	n/a
13	ATF2	chr21:15854378-15854908	GM12878	blood:	n/a	n/a
14	ATF2	chr21:15853089-15853541	GM12878	blood:	n/a	n/a
15	ATF2	chr21:15826640-15827476	GM12878	blood:	n/a	n/a
16	BACH1	chr21:15860270-15860682	K562	blood:	n/a	n/a
17	BACH1	chr21:15832752-15832934	K562	blood:	n/a	n/a
18	BATF	chr21:15787301-15787516	GM12878	blood:	n/a	n/a
19	BATF	chr21:15825702-15826017	GM12878	blood:	n/a	n/a
20	BATF	chr21:15826934-15827451	GM12878	blood:	n/a	n/a
21	BATF	chr21:15860387-15860678	GM12878	blood:	n/a	chr21:15860538-15860549
22	BATF	chr21:15859846-15860127	GM12878	blood:	n/a	chr21:15859990-15860001
23	BATF	chr21:15859850-15860070	GM12878	blood:	n/a	chr21:15859990-15860001
24	BCL11A	chr21:15825629-15826075	GM12878	blood:	n/a	n/a
25	BCL11A	chr21:15825724-15826047	GM12878	blood:	n/a	n/a
26	BCL3	chr21:15859110-15859550	K562	blood:	n/a	n/a
27	BCL3	chr21:15826774-15827451	GM12878	blood:	n/a	n/a
28	BCL3	chr21:15855694-15855965	K562	blood:	n/a	n/a
29	BCL3	chr21:15854468-15854908	GM12878	blood:	n/a	chr21:15854491-15854500
30	BCL3	chr21:15858528-15858784	K562	blood:	n/a	n/a
31	BCL3	chr21:15856102-15857552	K562	blood:	n/a	n/a
32	BCL3	chr21:15825598-15826117	GM12878	blood:	n/a	n/a
33	BCL3	chr21:15824794-15826225	GM12878	blood:	n/a	n/a
34	BCL3	chr21:15856280-15857370	K562	blood:	n/a	n/a
35	BCL3	chr21:15853078-15853572	GM12878	blood:	n/a	n/a
36	BCL3	chr21:15855353-15855613	K562	blood:	n/a	n/a
37	BCLAF1	chr21:15825660-15826120	GM12878	blood:	n/a	n/a
38	BCLAF1	chr21:15826562-15827587	GM12878	blood:	n/a	chr21:15826771-15826780
39	BCLAF1	chr21:15825539-15826489	GM12878	blood:	n/a	n/a
40	BHLHE40	chr21:15826715-15827378	GM12878	blood:	n/a	n/a
41	BHLHE40	chr21:15827674-15827676	K562	blood:	n/a	n/a
42	BHLHE40	chr21:15852791-15852937	K562	blood:	n/a	n/a
43	BHLHE40	chr21:15826614-15827444	K562	blood:	n/a	n/a
44	BHLHE40	chr21:15854472-15854941	GM12878	blood:	n/a	n/a
45	BHLHE40	chr21:15824053-15824178	GM12878	blood:	n/a	n/a
46	BHLHE40	chr21:15824894-15826142	GM12878	blood:	n/a	n/a
47	CBX3	chr21:15791230-15791584	K562	blood:	n/a	n/a
48	CBX3	chr21:15791238-15791580	K562	blood:	n/a	n/a
49	CCNT2	chr21:15824519-15824882	K562	blood:	n/a	chr21:15824677-15824697
50	CCNT2	chr21:15863617-15863976	K562	blood:	n/a	n/a

No data

(count:59 , 50 per page) page: 1 2

No.	Distal block	Cell Line	Cell type
1	chr21:15814489..15816453-chr21:15820620..15823655,3	K562	blood:
2	chr21:15833864..15836238-chr21:15845488..15848019,2	K562	blood:
3	chr21:15825624..15828360-chr21:15829254..15832008,4	K562	blood:
4	chr21:15827441..15829490-chr21:15833516..15835972,2	K562	blood:
5	chr21:15865993..15867759-chr21:15875544..15877082,2	K562	blood:
6	chr21:15848084..15850910-chr21:15854606..15856566,4	K562	blood:
7	chr21:15816301..15819436-chr21:15830607..15833716,3	K562	blood:
8	chr21:15857773..15859999-chr21:15862087..15863944,2	K562	blood:
9	chr21:15865993..15867759-chr21:15875544..15877082,2	K562	blood:
10	chr21:15830326..15832443-chr21:16163338..16165072,2	K562	blood:
11	chr21:15848084..15850910-chr21:15854606..15856566,4	K562	blood:
12	chr21:15881208..15883540-chr21:15886975..15889188,2	K562	blood:
13	chr21:15818489..15820512-chr21:15822543..15824167,2	K562	blood:
14	chr21:15844220..15846274-chr21:15867274..15869149,2	K562	blood:
15	chr21:15862079..15863579-chr6:26301955..26303620,2	K562	blood:
16	chr21:15863117..15865240-chr21:15875551..15877419,2	K562	blood:
17	chr21:15852608..15854130-chr21:15861560..15864028,2	K562	blood:
18	chr21:15842218..15844807-chr21:15848260..15850081,2	K562	blood:
19	chr21:15800225..15803025-chr21:15808190..15810823,2	K562	blood:
20	chr21:15857773..15859999-chr21:15862087..15863944,2	K562	blood:
21	chr21:15834401..15837014-chr21:15837761..15840673,3	K562	blood:
22	chr21:15818489..15820512-chr21:15822543..15824167,2	K562	blood:
23	chr21:15852608..15854130-chr21:15861560..15864028,2	K562	blood:
24	chr21:15863459..15867536-chr21:15871353..15874494,5	K562	blood:
25	chr21:15787706..15790405-chr21:16436901..16438934,2	MCF-7	breast:
26	chr21:15848828..15851671-chr21:15855558..15857437,2	MCF-7	breast:
27	chr21:15844220..15846274-chr21:15867274..15869149,2	K562	blood:
28	chr21:15860428..15863237-chr21:15863342..15865579,2	K562	blood:
29	chr21:15856459..15858933-chr21:16107429..16109946,2	K562	blood:
30	chr21:15867966..15869641-chr21:15871722..15874223,2	K562	blood:
31	chr21:15811840..15813659-chr21:15816381..15818147,3	K562	blood:
32	chr21:15800225..15803025-chr21:15808190..15810823,2	K562	blood:
33	chr21:15858969..15860796-chr21:15865823..15868637,2	MCF-7	breast:
34	chr21:15759229..15762199-chr21:15825176..15826732,2	K562	blood:
35	chr21:15814489..15816453-chr21:15820620..15823655,3	K562	blood:
36	chr21:15825624..15828360-chr21:15829254..15832008,4	K562	blood:
37	chr21:15833864..15836238-chr21:15845488..15848019,2	K562	blood:
38	chr21:15834401..15837014-chr21:15837761..15840673,3	K562	blood:
39	chr21:15852372..15854683-chr21:15916871..15919423,2	K562	blood:
40	chr21:15804069..15806738-chr21:15809728..15811411,2	K562	blood:
41	chr21:15875519..15877306-chr21:15885573..15888247,2	K562	blood:
42	chr21:15878918..15881751-chr21:15882365..15886915,4	K562	blood:
43	chr21:15876554..15878638-chr21:15883430..15885143,2	K562	blood:
44	chr21:15839769..15841961-chr21:15842594..15844538,2	K562	blood:
45	chr21:15863117..15865240-chr21:15875551..15877419,2	K562	blood:
46	chr21:15858969..15860796-chr21:15865823..15868637,2	MCF-7	breast:
47	chr21:15811840..15813659-chr21:15816381..15818147,3	K562	blood:
48	chr21:15804069..15806738-chr21:15809728..15811411,2	K562	blood:
49	chr21:15839769..15841961-chr21:15842594..15844538,2	K562	blood:
50	chr21:15816301..15819436-chr21:15830607..15833716,3	K562	blood:

(count:3 , 50 per page) page: 1

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-AF165138.7.1-5	chr21:15869460-15869600	l_2170_chr21:15869459-15921459_brain
2	lnc-HSPA13-1	chr21:15788122-15789088	NONHSAT081162
3	lnc-HSPA13-1	chr21:15789906-15790314	NONHSAT081162

No data

Variant related genes	Relation type
SAMSN1	TF binding region
ENSG00000225502	chromatin interactions
ENSG00000155307	chromatin interactions
ENSG00000180530	chromatin interactions

Extended variants
information (count: 2526 )
Associated
traits (count: 63 )

Variant overlapped rSNPs/rCNVs (count:2526 , 50 per page) page: 1 2 3 4 5 6 7 ... 51

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs556024454	chr21:15778003-15778004	Enhancers	n/a	n/a	Overlapped CNVs	n/a
2	rs113905762	chr21:15778012-15778013	Enhancers	n/a	n/a	Overlapped CNVs	n/a
3	rs188109063	chr21:15778016-15778017	Enhancers	n/a	n/a	Overlapped CNVs	n/a
4	rs111651022	chr21:15778025-15778026	Enhancers	n/a	n/a	Overlapped CNVs	n/a
5	rs4339028	chr21:15778109-15778110	Enhancers	n/a	n/a	Overlapped CNVs	n/a
6	rs143314809	chr21:15778110-15778111	Enhancers	n/a	n/a	Overlapped CNVs	n/a
7	rs148191590	chr21:15778130-15778131	Enhancers	n/a	n/a	Overlapped CNVs	n/a
8	rs377537408	chr21:15778136-15778137	Enhancers	n/a	n/a	Overlapped CNVs	n/a
9	rs370196413	chr21:15778155-15778156	Enhancers	n/a	n/a	Overlapped CNVs	n/a
10	rs575768689	chr21:15778206-15778207	Enhancers	n/a	n/a	Overlapped CNVs	n/a
11	rs147511397	chr21:15778275-15778276	Enhancers	n/a	n/a	Overlapped CNVs	n/a
12	rs115141687	chr21:15778292-15778293	Enhancers	n/a	n/a	Overlapped CNVs	n/a
13	rs140042782	chr21:15778397-15778398	Enhancers	n/a	n/a	Overlapped CNVs	n/a
14	rs3958171	chr21:15778399-15778400	Enhancers	n/a	n/a	Overlapped CNVs	n/a
15	rs192739459	chr21:15778400-15778401	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
16	rs552787674	chr21:15778434-15778435	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
17	rs185182916	chr21:15778447-15778448	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
18	rs142122454	chr21:15778454-15778455	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
19	rs541576010	chr21:15778470-15778471	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
20	rs113681687	chr21:15778479-15778480	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
21	rs542323010	chr21:15778482-15778483	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
22	rs139082562	chr21:15778492-15778493	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
23	rs149888095	chr21:15778495-15778496	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
24	rs575993729	chr21:15778504-15778505	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
25	rs533497486	chr21:15778508-15778509	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
26	rs547312920	chr21:15778545-15778546	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
27	rs9305311	chr21:15778557-15778558	Enhancers ZNF genes & repeats	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
28	rs200680086	chr21:15778591-15778592	Enhancers ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
29	rs529520820	chr21:15778605-15778606	Enhancers	n/a	n/a	Overlapped CNVs	n/a
30	rs562460743	chr21:15778606-15778607	Enhancers	n/a	n/a	Overlapped CNVs	n/a
31	rs549566002	chr21:15778651-15778652	Enhancers	n/a	n/a	Overlapped CNVs	n/a
32	rs146420875	chr21:15778781-15778782	Enhancers	n/a	n/a	Overlapped CNVs	n/a
33	rs9982971	chr21:15778793-15778794	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
34	rs531332954	chr21:15778794-15778795	Enhancers	n/a	n/a	Overlapped CNVs	n/a
35	rs571605438	chr21:15778800-15778801	Enhancers	n/a	n/a	Overlapped CNVs	n/a
36	rs539396594	chr21:15778801-15778802	Enhancers	n/a	n/a	Overlapped CNVs	n/a
37	rs552848940	chr21:15778883-15778884	Enhancers	n/a	n/a	Overlapped CNVs	n/a
38	rs572758702	chr21:15778892-15778893	Enhancers	n/a	n/a	Overlapped CNVs	n/a
39	rs377309380	chr21:15778909-15778910	Enhancers	n/a	n/a	Overlapped CNVs	n/a
40	rs551438956	chr21:15778933-15778934	Enhancers	n/a	n/a	Overlapped CNVs	n/a
41	rs9983469	chr21:15778950-15778951	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
42	rs374349158	chr21:15778952-15778953	Enhancers	n/a	n/a	Overlapped CNVs	n/a
43	rs190110433	chr21:15778954-15778955	Enhancers	n/a	n/a	Overlapped CNVs	n/a
44	rs141115019	chr21:15778971-15778972	Enhancers	n/a	n/a	Overlapped CNVs	n/a
45	rs73167399	chr21:15778991-15778992	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
46	rs563974693	chr21:15778992-15778993	Enhancers	n/a	n/a	Overlapped CNVs	n/a
47	rs192435398	chr21:15779014-15779015	Enhancers	n/a	n/a	Overlapped CNVs	n/a
48	rs184849461	chr21:15779038-15779039	Enhancers	n/a	n/a	Overlapped CNVs	n/a
49	rs560782818	chr21:15779050-15779051	Enhancers	n/a	n/a	Overlapped CNVs	n/a
50	rs529584864	chr21:15779059-15779060	Enhancers	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:63)

Disease	PMID	Source
Ovarian cancer	21720365	CNVD
Wilms tumour	21544195	CNVD
Esophageal cancer	21851588	CNVD
Glioblastoma multiforme	21080181	CNVD
Cancer	16751803	CNVD
Medulloblastoma	21979893	CNVD
Pleomorphic xanthoastrocytoma	20730472	CNVD
Down syndrome	17412756	CNVD
Down syndrome	17576883	CNVD
Acute promyelocytic leukemia	19109227	CNVD
T-cell prolymphocytic leukemia	17713554	CNVD
Autism	22495311	CNVD
Lung cancer	18438408	CNVD
Acute lymphoblastic leukemia	17690704	CNVD
Sudden cardiac death	19188705	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Acute myeloid leukemia	20729466	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
T-cell lymphomas	19863542	CNVD
Non-small cell lung cancer	21044232	CNVD
Non-syndromic sensorineural hearing loss	18471307	CNVD
Astrocytoma	17387387	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	21264507	CNVD
Glioblastoma multiforme	17387387	CNVD
Renal cell carcinoma	19461508	CNVD
Seminomas	18059402	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Acute lymphoblastic leukemia	21980252	CNVD
Metanephric adenoma	20802469	CNVD
Neuroblastoma	18923191	CNVD
Prostate cancer	19156837	CNVD
Basal cell lymphoma	17170743	CNVD
Follicular lymphoma	17170743	CNVD
Primary mediastinal b-cell lymphoma	17728785	CNVD
Cancer	20164919	CNVD
small cell lung cancer	20016488	CNVD
Acute lymphoblastic leukemia	21339820	CNVD
Breast cancer	20409316	CNVD
Autism	18414403	CNVD
Basal cell lymphoma	16317097	CNVD
Diffuse large b-cell lymphoma	16317097	CNVD
lymphocytic leukemia	21291569	CNVD
Hodgkin''s lymphoma	18641027	CNVD
Acute myeloid leukemia	21251322	CNVD
abnormal development	18461090	CNVD
Breast cancer	21785460	CNVD
Breast cancer	21364760	CNVD
Multiple myeloma	17550852	CNVD
Myelofibrosis	22110671	CNVD
Alzheimer''s disease	18923514	CNVD
Alzheimer''s disease	20877625	CNVD
Follicular lymphoma	20505157	CNVD
Alzheimer''s disease	21956041	CNVD
Cancer	21183584	CNVD
Non-syndromic sensorineural hearing loss	15273396	CNVD
Invasive pancreatic ductal carcinoma	16982739	CNVD
Melanoma	18172304	CNVD
Autism	22958593	CNVD
Schizophrenia	22958593	CNVD
Breast cancer	22522925	CNVD
Non-syndromic sensorineural hearing loss	22037309	CNVD
Non-syndromic sensorineural hearing loss	17122850	CNVD

Chromatin state (count:457 , 50 per page) page: 1 2 3 4 5 6 7 ... 10

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr21:15776400-15778400	Enhancers	Primary hematopoietic stem cells	blood
2	chr21:15777600-15778800	Enhancers	Primary hematopoietic stem cells short term culture	blood
3	chr21:15777600-15779000	Enhancers	Dnd41	blood
4	chr21:15778200-15779000	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
5	chr21:15778200-15779200	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Male	--
6	chr21:15778400-15778600	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
7	chr21:15778400-15778600	ZNF genes & repeats	Aorta	Aorta
8	chr21:15785200-15785400	Enhancers	iPS-15b Cell Line	embryonic stem cell
9	chr21:15786800-15788200	Enhancers	GM12878-XiMat	blood
10	chr21:15787000-15787600	Enhancers	iPS-15b Cell Line	embryonic stem cell
11	chr21:15787400-15787800	Enhancers	iPS-18 Cell Line	embryonic stem cell
12	chr21:15788600-15789800	ZNF genes & repeats	iPS DF 19.11 Cell Line	embryonic stem cell
13	chr21:15789800-15792200	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
14	chr21:15792200-15792400	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
15	chr21:15810000-15810600	Enhancers	Primary neutrophils fromperipheralblood	blood
16	chr21:15810600-15811000	Enhancers	Monocytes-CD14+_RO01746	blood
17	chr21:15810600-15811200	Flanking Active TSS	Primary neutrophils fromperipheralblood	blood
18	chr21:15810600-15811600	Enhancers	Primary monocytes fromperipheralblood	blood
19	chr21:15811000-15811200	Enhancers	Primary B cells from cord blood	blood
20	chr21:15811200-15811800	Enhancers	Primary neutrophils fromperipheralblood	blood
21	chr21:15816600-15819000	Enhancers	K562	blood
22	chr21:15819000-15822400	Weak transcription	K562	blood
23	chr21:15821000-15821200	Enhancers	Primary T killer memory cells from peripheral blood	blood
24	chr21:15822400-15823800	Enhancers	K562	blood
25	chr21:15823000-15825000	Enhancers	GM12878-XiMat	blood
26	chr21:15823600-15826400	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Male	--
27	chr21:15823800-15827400	Enhancers	Primary T helper 17 cells PMA-I stimulated	--
28	chr21:15823800-15828000	Flanking Active TSS	K562	blood
29	chr21:15824000-15828000	Enhancers	Primary T helper memory cells from peripheral blood 2	blood
30	chr21:15824000-15828200	Enhancers	Primary hematopoietic stem cells short term culture	blood
31	chr21:15824000-15828600	Enhancers	Primary hematopoietic stem cells	blood
32	chr21:15824200-15828200	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
33	chr21:15824400-15824800	Enhancers	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
34	chr21:15824600-15825000	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
35	chr21:15824600-15825000	Enhancers	Primary T helper cells fromperipheralblood	blood
36	chr21:15824800-15825200	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
37	chr21:15825000-15825400	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
38	chr21:15825000-15825400	Weak transcription	Primary T helper cells fromperipheralblood	blood
39	chr21:15825000-15827600	Flanking Active TSS	GM12878-XiMat	blood
40	chr21:15825200-15825400	Enhancers	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
41	chr21:15825400-15825600	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
42	chr21:15825400-15825600	Enhancers	Primary T helper cells fromperipheralblood	blood
43	chr21:15825400-15826600	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
44	chr21:15825600-15826400	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
45	chr21:15825600-15826800	Weak transcription	Primary T helper cells fromperipheralblood	blood
46	chr21:15826000-15827000	Enhancers	Pancreatic Islets	Pancreatic Islet
47	chr21:15826200-15827400	Enhancers	Fetal Intestine Large	intestine
48	chr21:15826200-15827400	Enhancers	Rectal Mucosa Donor 31	rectum
49	chr21:15826200-15827400	Enhancers	Sigmoid Colon	Sigmoid Colon
50	chr21:15826400-15826800	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived

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