Variant report

Variant	nsv576424
Chromosome Location	chr18:7740473-7761056
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ARID3A	chr18:7754639-7755251	HepG2	liver:	n/a	n/a
2	ARID3A	chr18:7755669-7756066	HepG2	liver:	n/a	n/a
3	ARID3A	chr18:7749782-7750123	HepG2	liver:	n/a	n/a
4	BHLHE40	chr18:7753528-7753535	GM12878	blood:	n/a	n/a
5	CEBPB	chr18:7755769-7756053	Hela-S3	cervix:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
6	CEBPB	chr18:7754658-7755189	HepG2	liver:	n/a	n/a
7	CEBPB	chr18:7757346-7757484	HepG2	liver:	n/a	chr18:7757399-7757410
8	CEBPB	chr18:7755768-7756016	MCF-7	breast:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
9	CEBPB	chr18:7743361-7743507	H1-hESC	embryonic stem cell:	n/a	chr18:7743467-7743478 chr18:7743455-7743466 chr18:7743456-7743467
10	CEBPB	chr18:7755658-7756217	A549	lung:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
11	CEBPB	chr18:7757245-7757538	IMR90	lung:	n/a	chr18:7757399-7757410
12	CEBPB	chr18:7755844-7756009	HepG2	liver:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
13	CEBPB	chr18:7755740-7756370	HepG2	liver:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
14	CEBPB	chr18:7743291-7743630	HepG2	liver:	n/a	chr18:7743467-7743478 chr18:7743455-7743466 chr18:7743456-7743467
15	CEBPB	chr18:7755730-7756076	HepG2	liver:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
16	CEBPB	chr18:7755770-7756057	K562	blood:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
17	CEBPB	chr18:7749687-7750078	HepG2	liver:	n/a	n/a
18	CEBPB	chr18:7755791-7756068	A549	lung:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
19	CEBPB	chr18:7754719-7755107	HepG2	liver:	n/a	n/a
20	CEBPB	chr18:7743284-7743614	IMR90	lung:	n/a	chr18:7743467-7743478 chr18:7743455-7743466 chr18:7743456-7743467
21	CEBPB	chr18:7751013-7751174	HepG2	liver:	n/a	n/a
22	CEBPB	chr18:7757249-7757585	A549	lung:	n/a	chr18:7757399-7757410
23	CEBPB	chr18:7757160-7757659	A549	lung:	n/a	chr18:7757399-7757410
24	CEBPB	chr18:7755734-7756078	A549	lung:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
25	CEBPB	chr18:7743286-7743615	A549	lung:	n/a	chr18:7743467-7743478 chr18:7743455-7743466 chr18:7743456-7743467
26	CEBPB	chr18:7755866-7756067	H1-hESC	embryonic stem cell:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
27	CEBPB	chr18:7755758-7756128	MCF-7	breast:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
28	CEBPB	chr18:7743291-7743549	Hela-S3	cervix:	n/a	chr18:7743467-7743478 chr18:7743455-7743466 chr18:7743456-7743467
29	CEBPB	chr18:7755754-7756077	HepG2	liver:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
30	CEBPB	chr18:7755757-7756106	IMR90	lung:	n/a	chr18:7755923-7755932 chr18:7755921-7755934 chr18:7755923-7755934 chr18:7755921-7755932
31	CEBPB	chr18:7750692-7751262	HepG2	liver:	n/a	chr18:7750816-7750833
32	CEBPD	chr18:7754686-7755097	HepG2	liver:	n/a	n/a
33	CREB1	chr18:7754719-7755043	A549	lung:	n/a	n/a
34	CTCF	chr18:7755820-7755970	HMEC	breast:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
35	CTCF	chr18:7754940-7755090	Caco-2	colon:	n/a	chr18:7755005-7755018
36	CTCF	chr18:7755860-7756010	NHDF-neo	bronchial:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
37	CTCF	chr18:7755840-7755990	HPAF	blood vessel:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
38	CTCF	chr18:7755753-7756067	HepG2	liver:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
39	CTCF	chr18:7748401-7748455	Fibrobl	skin:	n/a	n/a
40	CTCF	chr18:7755780-7755930	HBMEC	blood vessel:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
41	CTCF	chr18:7755860-7756010	HPF	lung:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
42	CTCF	chr18:7755860-7756010	HEEpiC	esophagus:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
43	CTCF	chr18:7755811-7756011	HUVEC	blood vessel:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
44	CTCF	chr18:7755800-7755950	HA-sp	spinal cord:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
45	CTCF	chr18:7755780-7755930	MCF-7	breast:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
46	CTCF	chr18:7755860-7756010	HCFaa	heart:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
47	CTCF	chr18:7755820-7755970	RPTEC	kidney:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
48	CTCF	chr18:7755786-7755994	HepG2	liver:	n/a	chr18:7755889-7755905 chr18:7755883-7755904 chr18:7755893-7755901
49	CTCF	chr18:7755660-7755810	HAc	cerebellar:	n/a	n/a
50	CTCF	chr18:7755865-7755897	NHEK	skin:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr18:7755817..7756409-chr5:151977437..151978212,2	MCF-7	breast:
2	chr18:7745866..7749831-chr18:7752461..7755443,3	MCF-7	breast:
3	chr18:7749744..7751445-chr18:7751627..7754409,2	MCF-7	breast:
4	chr18:7749744..7751445-chr18:7751627..7754409,2	MCF-7	breast:
5	chr18:7747994..7750042-chr18:7751326..7753624,2	K562	blood:
6	chr18:7745866..7749831-chr18:7752461..7755443,3	MCF-7	breast:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-LAMA1-5	chr18:7751018-7751503	ENSG00000266767.1
2	lnc-LAMA1-5	chr18:7749057-7749441	ENSG00000266767.1
3	lnc-LAMA1-5	chr18:7740621-7741979	NONHSAT057159
4	lnc-LAMA1-5	chr18:7741308-7741979	ENSG00000266767.1
5	lnc-LAMA1-5	chr18:7749057-7749441	NONHSAT057159
6	lnc-LAMA1-5	chr18:7747531-7747656	ENSG00000266767.1
7	lnc-LAMA1-5	chr18:7754762-7754829	ENSG00000266767.1
8	lnc-LAMA1-5	chr18:7749057-7749197	ENSG00000266767.1

Variant related genes	Relation type
ENSG00000266767	TF binding region
PTPRM	TF binding region
ENSG00000221631	TF binding region
ENSG00000173482	chromatin interactions
ENSG00000266767	chromatin interactions

Extended variants
information (count: 693 )
Associated
traits (count: 57 )

Variant overlapped rSNPs/rCNVs (count:693 , 50 per page) page: 1 2 3 4 5 6 7 ... 14

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs664592	chr18:7740473-7740474	Weak transcription Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
2	rs537979374	chr18:7740475-7740476	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
3	rs75731663	chr18:7740490-7740491	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
4	rs568133215	chr18:7740556-7740557	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
5	rs533902561	chr18:7740562-7740563	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
6	rs568477170	chr18:7740569-7740570	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
7	rs554131562	chr18:7740571-7740572	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
8	rs147494807	chr18:7740579-7740580	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
9	rs546060988	chr18:7740615-7740616	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
10	rs377263582	chr18:7740687-7740688	Weak transcription Enhancers	lncRNA	n/a	Overlapped CNVs	n/a
11	rs536026970	chr18:7740696-7740697	Weak transcription Enhancers	lncRNA	n/a	Overlapped CNVs	n/a
12	rs180726162	chr18:7740737-7740738	Weak transcription Enhancers	lncRNA	n/a	Overlapped CNVs	n/a
13	rs183748622	chr18:7740744-7740745	Weak transcription Enhancers	lncRNA	n/a	Overlapped CNVs	n/a
14	rs190553592	chr18:7740789-7740790	Weak transcription Enhancers	lncRNA	n/a	Overlapped CNVs	n/a
15	rs567679786	chr18:7740815-7740816	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
16	rs182327732	chr18:7740823-7740824	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
17	rs536621417	chr18:7740830-7740831	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
18	rs370007412	chr18:7740846-7740847	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
19	rs540717734	chr18:7740917-7740918	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
20	rs13380901	chr18:7740925-7740926	Enhancers Weak transcription Flanking Active TSS	TF binding region lncRNA	1 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
21	rs139305927	chr18:7740936-7740937	Enhancers Weak transcription Flanking Active TSS	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
22	rs536523745	chr18:7740959-7740960	Enhancers Weak transcription Flanking Active TSS	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
23	rs369241324	chr18:7741020-7741021	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
24	rs562767647	chr18:7741030-7741031	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
25	rs531758290	chr18:7741034-7741035	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
26	rs34464041	chr18:7741041-7741042	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
27	rs149622531	chr18:7741042-7741043	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
28	rs371465635	chr18:7741045-7741046	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
29	rs144330402	chr18:7741069-7741070	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
30	rs534289216	chr18:7741096-7741097	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
31	rs186930674	chr18:7741107-7741108	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
32	rs13381592	chr18:7741131-7741132	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
33	rs539766104	chr18:7741172-7741173	Enhancers Weak transcription	lncRNA	n/a	Overlapped CNVs	n/a
34	rs540379660	chr18:7741199-7741200	Enhancers Weak transcription	lncRNA	n/a	Overlapped CNVs	n/a
35	rs556462913	chr18:7741245-7741246	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
36	rs576311625	chr18:7741289-7741290	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
37	rs148801815	chr18:7741295-7741296	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
38	rs555599859	chr18:7741321-7741322	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
39	rs386800909	chr18:7741339-7741340	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
40	rs146424416	chr18:7741340-7741341	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
41	rs538872967	chr18:7741355-7741356	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
42	rs563954307	chr18:7741396-7741397	Enhancers Weak transcription Flanking Active TSS	lncRNA	n/a	Overlapped CNVs	n/a
43	rs577541252	chr18:7741450-7741451	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
44	rs546106654	chr18:7741561-7741562	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
45	rs558443914	chr18:7741562-7741563	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
46	rs613706	chr18:7741580-7741581	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
47	rs562820203	chr18:7741684-7741685	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
48	rs117836892	chr18:7741739-7741740	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
49	rs117160140	chr18:7741740-7741741	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a
50	rs562290950	chr18:7741794-7741795	Enhancers Weak transcription	TF binding region lncRNA	1 gene(s)	Overlapped CNVs	n/a

Variant related diseases (count:57)

Disease	PMID	Source
Acute lymphoblastic leukemia	17690704	CNVD
Melanoma	18172304	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Intellectual disability	22102821	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Acute myeloid leukemia	16864856	CNVD
Seminomas	18059402	CNVD
Chronic lymphocytic leukemia	18922857	CNVD
Kartagener syndrome	16639409	CNVD
Basal cell lymphoma	21115979	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	21264507	CNVD
Cancer	21183584	CNVD
Esophageal squamous carcinoma	18350619	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
Basal cell lymphoma	17053054	CNVD
Colorectal cancer	19359472	CNVD
Human rectal carcinomas	16397240	CNVD
Colorectal cancer	16272173	CNVD
Colorectal cancer	19150955	CNVD
Follicular lymphoma	20505157	CNVD
Chordoma	21602918	CNVD
Ewing''s sarcoma	21437220	CNVD
Neuroblastoma	18923191	CNVD
Glioblastoma multiforme	21080181	CNVD
Cancer	21637783	CNVD
Medulloblastoma	21979893	CNVD
Splenic marginal zone lymphoma	21957467	CNVD
Trisomy 18 syndrome	17576883	CNVD
Urothelial carcinoma	21177765	CNVD
Lung cancer	18438408	CNVD
Breast cancer	21785460	CNVD
Autism	20808228	CNVD
lymphocytic leukemia	21291569	CNVD
T-cell prolymphocytic leukemia	17713554	CNVD
Barrett''s syndrome	19417022	CNVD
Hodgkin''s lymphoma	17606441	CNVD
low-grade B-cell lymphoma tumor	18367492	CNVD
Ewing''s sarcoma	17952124	CNVD
Multiple myeloma	17550852	CNVD
Developmental delay	21147756	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Thoracic aortic aneurysm	21092924	CNVD
Breast cancer	21364760	CNVD
Breast cancer	21858162	CNVD
small cell lung cancer	20016488	CNVD
abnormal development	18461090	CNVD
Breast cancer	17133270	CNVD
Heart disease	21282601	CNVD
Glioblastoma multiforme	21922591	CNVD
Basal cell lymphoma	16317097	CNVD
Diffuse large b-cell lymphoma	16317097	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Acute myeloid leukemia	17377590	CNVD
Schizophrenia	20838587	CNVD
Pancreatic cancer	17952125	CNVD
Breast cancer	22522925	CNVD

Chromatin state (count:524 , 50 per page) page: 1 2 3 4 5 6 7 ... 11

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr18:7734200-7741000	Weak transcription	Aorta	Aorta
2	chr18:7734400-7741000	Weak transcription	Right Ventricle	heart
3	chr18:7734600-7745600	Weak transcription	Duodenum Smooth Muscle	Duodenum
4	chr18:7735200-7740800	Weak transcription	iPS-15b Cell Line	embryonic stem cell
5	chr18:7735200-7743000	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
6	chr18:7735200-7745200	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
7	chr18:7735400-7741200	Weak transcription	Psoas Muscle	Psoas
8	chr18:7735400-7745200	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
9	chr18:7735800-7740800	Weak transcription	iPS-18 Cell Line	embryonic stem cell
10	chr18:7735800-7741200	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
11	chr18:7735800-7745200	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
12	chr18:7736200-7740600	Weak transcription	Fetal Heart	heart
13	chr18:7736200-7740800	Weak transcription	HepG2	liver
14	chr18:7736200-7745000	Weak transcription	A549	lung
15	chr18:7737800-7741000	Weak transcription	Skeletal Muscle Male	skeletal muscle
16	chr18:7737800-7741200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
17	chr18:7737800-7746800	Weak transcription	Spleen	Spleen
18	chr18:7737800-7748400	Weak transcription	Gastric	stomach
19	chr18:7738000-7740800	Weak transcription	Adipose Nuclei	Adipose
20	chr18:7738000-7741200	Weak transcription	Lung	lung
21	chr18:7738000-7746600	Weak transcription	Right Atrium	heart
22	chr18:7738600-7742000	Enhancers	Fetal Thymus	thymus
23	chr18:7738800-7741400	Enhancers	Thymus	Thymus
24	chr18:7739000-7746800	Weak transcription	Pancreas	Pancrea
25	chr18:7739000-7750600	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
26	chr18:7739600-7742000	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
27	chr18:7739600-7743200	Enhancers	Fetal Muscle Leg	muscle
28	chr18:7739800-7740800	Weak transcription	ES-I3 Cell Line	embryonic stem cell
29	chr18:7739800-7740800	Weak transcription	H1 Cell Line	embryonic stem cell
30	chr18:7739800-7740800	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
31	chr18:7739800-7741200	Weak transcription	H9 Cell Line	embryonic stem cell
32	chr18:7739800-7741600	Enhancers	Fetal Kidney	kidney
33	chr18:7740000-7741400	Weak transcription	Colon Smooth Muscle	Colon
34	chr18:7740000-7742800	Enhancers	Fetal Stomach	stomach
35	chr18:7740200-7740600	Weak transcription	HUES6 Cell Line	embryonic stem cell
36	chr18:7740200-7740600	Weak transcription	HUES64 Cell Line	embryonic stem cell
37	chr18:7740200-7740800	Enhancers	Stomach Smooth Muscle	stomach
38	chr18:7740200-7741200	Weak transcription	Left Ventricle	heart
39	chr18:7740200-7742600	Weak transcription	Fetal Muscle Trunk	muscle
40	chr18:7740400-7740600	Enhancers	Small Intestine	intestine
41	chr18:7740400-7740800	Weak transcription	HUES48 Cell Line	embryonic stem cell
42	chr18:7740400-7740800	Weak transcription	iPS-20b Cell Line	embryonic stem cell
43	chr18:7740400-7741200	Enhancers	Fetal Lung	lung
44	chr18:7740600-7741400	Enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
45	chr18:7740600-7742200	Enhancers	HUES6 Cell Line	embryonic stem cell
46	chr18:7740600-7742200	Enhancers	Fetal Heart	heart
47	chr18:7740600-7742400	Enhancers	HUES64 Cell Line	embryonic stem cell
48	chr18:7740800-7741000	Flanking Active TSS	Stomach Smooth Muscle	stomach
49	chr18:7740800-7741400	Enhancers	Breast Myoepithelial Primary Cells	Breast
50	chr18:7740800-7741400	Enhancers	HepG2	liver

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