Variant report

Variant	nsv909405
Chromosome Location	chr18:12727224-12750499
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:882)
CpG islands
(count:0)
Chromatin interactive
region (count:31)
LncRNA
region (count:10)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:882 , 50 per page) page: 1 2 3 4 5 6 7 ... 18

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ARID3A	chr18:12744313-12744513	K562	blood:	n/a	n/a
2	ARID3A	chr18:12741358-12741657	K562	blood:	n/a	n/a
3	ARID3A	chr18:12741272-12741742	HepG2	liver:	n/a	n/a
4	ARID3A	chr18:12744199-12744583	HepG2	liver:	n/a	n/a
5	ARID3A	chr18:12727057-12727341	HepG2	liver:	n/a	n/a
6	ARID3A	chr18:12742618-12742679	HepG2	liver:	n/a	n/a
7	ARID3A	chr18:12727087-12727397	K562	blood:	n/a	n/a
8	ARID3A	chr18:12729995-12730742	HepG2	liver:	n/a	n/a
9	BACH1	chr18:12744209-12744299	K562	blood:	n/a	n/a
10	BCL3	chr18:12741258-12741792	A549	lung:	n/a	n/a
11	BCL3	chr18:12742534-12742768	GM12878	blood:	n/a	n/a
12	BCL3	chr18:12730168-12730563	A549	lung:	n/a	n/a
13	BCL3	chr18:12741291-12741799	A549	lung:	n/a	n/a
14	BHLHE40	chr18:12727057-12727412	HepG2	liver:	n/a	n/a
15	BHLHE40	chr18:12727121-12727504	GM12878	blood:	n/a	n/a
16	BHLHE40	chr18:12727082-12727313	K562	blood:	n/a	n/a
17	BHLHE40	chr18:12730265-12730520	HepG2	liver:	n/a	n/a
18	BHLHE40	chr18:12741439-12741588	K562	blood:	n/a	n/a
19	BRCA1	chr18:12741310-12741757	Hela-S3	cervix:	n/a	n/a
20	BRCA1	chr18:12727020-12727405	Hela-S3	cervix:	n/a	n/a
21	BRCA1	chr18:12727189-12727257	GM12878	blood:	n/a	n/a
22	CBX3	chr18:12730109-12730463	K562	blood:	n/a	n/a
23	CBX3	chr18:12730210-12730467	HCT-116	colon:	n/a	n/a
24	CEBPB	chr18:12742451-12742842	IMR90	lung:	n/a	n/a
25	CEBPB	chr18:12734395-12734523	HepG2	liver:	n/a	chr18:12734425-12734436
26	CEBPB	chr18:12748762-12749053	Hela-S3	cervix:	n/a	n/a
27	CEBPB	chr18:12748802-12749022	IMR90	lung:	n/a	n/a
28	CEBPB	chr18:12727020-12727468	MCF-7	breast:	n/a	n/a
29	CEBPB	chr18:12741378-12741809	A549	lung:	n/a	n/a
30	CEBPB	chr18:12727059-12727450	Hela-S3	cervix:	n/a	n/a
31	CEBPB	chr18:12741344-12741785	MCF-7	breast:	n/a	n/a
32	CEBPB	chr18:12727100-12727410	H1-hESC	embryonic stem cell:	n/a	n/a
33	CEBPB	chr18:12734314-12734525	IMR90	lung:	n/a	chr18:12734425-12734436
34	CEBPB	chr18:12741303-12741829	A549	lung:	n/a	n/a
35	CEBPB	chr18:12741538-12741667	K562	blood:	n/a	n/a
36	CEBPB	chr18:12736181-12736342	HepG2	liver:	n/a	n/a
37	CEBPB	chr18:12742525-12742831	A549	lung:	n/a	n/a
38	CEBPB	chr18:12734396-12734478	K562	blood:	n/a	chr18:12734425-12734436
39	CEBPB	chr18:12734284-12734515	Hela-S3	cervix:	n/a	chr18:12734425-12734436
40	CEBPB	chr18:12727100-12727463	A549	lung:	n/a	n/a
41	CEBPB	chr18:12741362-12741712	HepG2	liver:	n/a	n/a
42	CEBPB	chr18:12741252-12741991	Hela-S3	cervix:	n/a	n/a
43	CEBPB	chr18:12742440-12742852	Hela-S3	cervix:	n/a	n/a
44	CEBPB	chr18:12742530-12742801	A549	lung:	n/a	n/a
45	CEBPB	chr18:12741369-12741877	MCF-7	breast:	n/a	n/a
46	CEBPB	chr18:12727105-12727469	K562	blood:	n/a	n/a
47	CEBPB	chr18:12741354-12741832	A549	lung:	n/a	n/a
48	CEBPB	chr18:12730154-12730528	Hela-S3	cervix:	n/a	n/a
49	CEBPB	chr18:12727050-12727470	A549	lung:	n/a	n/a
50	CEBPB	chr18:12742391-12742920	A549	lung:	n/a	n/a

No data

(count:31 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr18:12726635..12727970-chr18:12934143..12935576,12	K562	blood:
2	chr18:12727153..12728721-chr18:12742306..12744471,2	K562	blood:
3	chr18:12736365..12739403-chr18:12741329..12744252,3	K562	blood:
4	chr18:12726736..12727393-chr18:12846308..12846890,2	MCF-7	breast:
5	chr18:12736365..12739403-chr18:12741329..12744252,3	K562	blood:
6	chr18:12726304..12729223-chr18:12948825..12951791,2	K562	blood:
7	chr18:12726793..12727997-chr18:12893494..12894384,4	K562	blood:
8	chr18:12737122..12738632-chr18:12946141..12947768,2	K562	blood:
9	chr18:12725757..12728002-chr18:12765870..12768020,2	K562	blood:
10	chr18:12743947..12744773-chr18:12893871..12894501,3	MCF-7	breast:
11	chr18:12726771..12727633-chr18:12766775..12767717,3	MCF-7	breast:
12	chr18:12743547..12744839-chr18:12934192..12935152,4	MCF-7	breast:
13	chr18:12737134..12739403-chr18:12741329..12744252,2	K562	blood:
14	chr18:12726857..12727908-chr18:12766755..12767707,3	K562	blood:
15	chr18:12701170..12703824-chr18:12734479..12737400,3	K562	blood:
16	chr18:12725367..12727823-chr18:12887215..12889210,2	K562	blood:
17	chr18:12743899..12744821-chr18:12934195..12935067,5	MCF-7	breast:
18	chr18:12727418..12729485-chr18:12735947..12737729,2	MCF-7	breast:
19	chr18:12735991..12737957-chr18:12882533..12884666,2	MCF-7	breast:
20	chr18:12720684..12722477-chr18:12725807..12728558,2	MCF-7	breast:
21	chr18:12740652..12742323-chr18:12932968..12935148,2	MCF-7	breast:
22	chr18:12731181..12733773-chr18:12882948..12885261,2	MCF-7	breast:
23	chr18:12737957..12738483-chr18:12934210..12934922,2	MCF-7	breast:
24	chr18:12727418..12729485-chr18:12735947..12737729,2	MCF-7	breast:
25	chr18:12741288..12744269-chr18:12942770..12945438,2	MCF-7	breast:
26	chr18:12737134..12739403-chr18:12741329..12744252,2	K562	blood:
27	chr18:12740701..12743210-chr18:12882198..12885032,2	MCF-7	breast:
28	chr18:12689725..12692648-chr18:12725870..12727791,2	K562	blood:
29	chr18:12727153..12728721-chr18:12742306..12744471,2	K562	blood:
30	chr18:12726953..12727699-chr18:12934094..12935046,3	MCF-7	breast:
31	chr18:12744227..12744814-chr18:12934130..12935168,6	K562	blood:

(count:10 , 50 per page) page: 1

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-PTPN2-5	chr18:12750009-12750067	ENSG00000266961.1
2	lnc-PTPN2-2	chr18:12749293-12749484	XLOC_012776
3	lnc-PTPN2-2	chr18:12739707-12739929	NONHSAT058390
4	lnc-PTPN2-2	chr18:12749293-12749420	ENSG00000267654.1
5	lnc-PTPN2-2	chr18:12749293-12749532	NONHSAT058391
6	lnc-PTPN2-2	chr18:12739707-12739929	NONHSAT058391
7	lnc-PTPN2-2	chr18:12739489-12739929	ENSG00000267654.1
8	lnc-PTPN2-2	chr18:12739784-12739929	XLOC_012776
9	lnc-PTPN2-2	chr18:12749293-12749620	NONHSAT058390
10	lnc-PTPN2-5	chr18:12738964-12739214	ENSG00000266961.1

No data

Variant related genes	Relation type
ENSG00000267654	TF binding region
ENSG00000266961	TF binding region
ENSG00000085415	chromatin interactions
ENSG00000101624	chromatin interactions
ENSG00000175354	chromatin interactions
ENSG00000128789	chromatin interactions
FOXO3	miRNA target sites

Extended variants
information (count: 926 )
Associated
traits (count: 55 )

Variant overlapped rSNPs/rCNVs (count:926 , 50 per page) page: 1 2 3 4 5 6 7 ... 19

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs2847254	chr18:12727224-12727225	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
2	rs573041465	chr18:12727253-12727254	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
3	rs545168884	chr18:12727263-12727264	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
4	rs150963464	chr18:12727287-12727288	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
5	rs550487016	chr18:12727290-12727291	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
6	rs117153182	chr18:12727305-12727306	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
7	rs568749877	chr18:12727321-12727322	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
8	rs558840804	chr18:12727335-12727336	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
9	rs377621450	chr18:12727348-12727349	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
10	rs561470794	chr18:12727358-12727359	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
11	rs531713535	chr18:12727395-12727396	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
12	rs184219164	chr18:12727408-12727409	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
13	rs550234690	chr18:12727414-12727415	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
14	rs12966082	chr18:12727418-12727419	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
15	rs139533190	chr18:12727421-12727422	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
16	rs547231843	chr18:12727437-12727438	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
17	rs186693277	chr18:12727476-12727477	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
18	rs375367017	chr18:12727495-12727496	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
19	rs149689247	chr18:12727496-12727497	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
20	rs576287535	chr18:12727513-12727514	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
21	rs536613491	chr18:12727524-12727525	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	Overlapped CNVs	n/a
22	rs34537593	chr18:12727596-12727597	Weak transcription Strong transcription Genic enhancers Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
23	rs576483367	chr18:12727634-12727635	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
24	rs533855586	chr18:12727640-12727641	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
25	rs540736189	chr18:12727689-12727690	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
26	rs201437435	chr18:12727694-12727695	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
27	rs559220175	chr18:12727704-12727705	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
28	rs115531281	chr18:12727772-12727773	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
29	rs542879471	chr18:12727798-12727799	Weak transcription Strong transcription	n/a	n/a	Overlapped CNVs	n/a
30	rs191553071	chr18:12727831-12727832	Weak transcription Strong transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
31	rs558487572	chr18:12727861-12727862	Weak transcription Strong transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
32	rs116838754	chr18:12727928-12727929	Weak transcription Strong transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
33	rs550173255	chr18:12727946-12727947	Weak transcription Strong transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
34	rs565285567	chr18:12728067-12728068	Weak transcription ZNF genes & repeats Strong transcription	n/a	n/a	Overlapped CNVs	n/a
35	rs183842524	chr18:12728094-12728095	Weak transcription ZNF genes & repeats Strong transcription	n/a	n/a	Overlapped CNVs	n/a
36	rs547860154	chr18:12728114-12728115	Weak transcription ZNF genes & repeats Strong transcription	n/a	n/a	Overlapped CNVs	n/a
37	rs140234208	chr18:12728122-12728123	Weak transcription ZNF genes & repeats Strong transcription	n/a	n/a	Overlapped CNVs	n/a
38	rs377186298	chr18:12728183-12728184	Weak transcription ZNF genes & repeats Strong transcription	n/a	n/a	Overlapped CNVs	n/a
39	rs532903771	chr18:12728203-12728204	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
40	rs369953857	chr18:12728204-12728205	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
41	rs2847253	chr18:12728245-12728246	Weak transcription ZNF genes & repeats	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
42	rs548096759	chr18:12728300-12728301	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
43	rs569585867	chr18:12728307-12728308	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
44	rs536948938	chr18:12728327-12728328	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
45	rs558087040	chr18:12728353-12728354	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
46	rs576420765	chr18:12728365-12728366	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
47	rs534362802	chr18:12728399-12728400	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
48	rs553010222	chr18:12728425-12728426	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
49	rs188566205	chr18:12728459-12728460	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a
50	rs543172769	chr18:12728478-12728479	Weak transcription ZNF genes & repeats	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:55)

Disease	PMID	Source
Chronic lymphocytic leukemia	21546498	CNVD
Intellectual disability	22102821	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Acute myeloid leukemia	16864856	CNVD
Seminomas	18059402	CNVD
Chronic lymphocytic leukemia	18922857	CNVD
Kartagener syndrome	16639409	CNVD
Basal cell lymphoma	21115979	CNVD
Endometrial cancer	22040021	CNVD
Breast cancer	21264507	CNVD
Cancer	21183584	CNVD
Esophageal squamous carcinoma	18350619	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
Basal cell lymphoma	17053054	CNVD
Colorectal cancer	19359472	CNVD
Human rectal carcinomas	16397240	CNVD
Melanoma	18172304	CNVD
Colorectal cancer	16272173	CNVD
Colorectal cancer	19150955	CNVD
Follicular lymphoma	20505157	CNVD
Chordoma	21602918	CNVD
Ewing''s sarcoma	21437220	CNVD
Neuroblastoma	18923191	CNVD
Glioblastoma multiforme	21080181	CNVD
Cancer	21637783	CNVD
Medulloblastoma	21979893	CNVD
Splenic marginal zone lymphoma	21957467	CNVD
Trisomy 18 syndrome	17576883	CNVD
Autism	20808228	CNVD
lymphocytic leukemia	21291569	CNVD
Barrett''s syndrome	19417022	CNVD
Hodgkin''s lymphoma	17606441	CNVD
Ewing''s sarcoma	17952124	CNVD
Multiple myeloma	17550852	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Thoracic aortic aneurysm	21092924	CNVD
Breast cancer	21364760	CNVD
small cell lung cancer	20016488	CNVD
Heart disease	21282601	CNVD
Glioblastoma multiforme	21922591	CNVD
Basal cell lymphoma	16317097	CNVD
Diffuse large b-cell lymphoma	16317097	CNVD
low-grade B-cell lymphoma tumor	18367492	CNVD
Acute myeloid leukemia	17377590	CNVD
Acute lymphoblastic leukemia	17690704	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Acute lymphoblastic leukemia	21339820	CNVD
Developmental delay	21147756	CNVD
Lung cancer	18438408	CNVD
Breast cancer	16620391	CNVD
Myelofibrosis	22110671	CNVD
Retinoblastoma	21504564	CNVD
Glioma	17123091	CNVD
Neurodevelopmental disorder	22521361	CNVD
Non-syndromic sensorineural hearing loss	21293372	CNVD

Chromatin state (count:332 , 50 per page) page: 1 2 3 4 5 6 7

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr18:12704800-12727800	Strong transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
2	chr18:12705000-12728600	Weak transcription	Stomach Mucosa	stomach
3	chr18:12714600-12728800	Weak transcription	Esophagus	oesophagus
4	chr18:12719000-12727800	Strong transcription	Sigmoid Colon	Sigmoid Colon
5	chr18:12720600-12727800	Strong transcription	HUVEC	blood vessel
6	chr18:12721800-12728200	Strong transcription	HSMM	muscle
7	chr18:12723000-12728600	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
8	chr18:12723000-12748400	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
9	chr18:12723200-12728600	Weak transcription	Aorta	Aorta
10	chr18:12723400-12728200	Weak transcription	Small Intestine	intestine
11	chr18:12723400-12728600	Weak transcription	Colon Smooth Muscle	Colon
12	chr18:12723600-12728400	Weak transcription	Rectal Smooth Muscle	rectum
13	chr18:12724200-12730000	Weak transcription	K562	blood
14	chr18:12724600-12728200	Weak transcription	Fetal Kidney	kidney
15	chr18:12724600-12728400	Weak transcription	Psoas Muscle	Psoas
16	chr18:12724600-12728600	Weak transcription	Ovary	ovary
17	chr18:12724600-12729600	Weak transcription	Fetal Brain Female	brain
18	chr18:12724600-12729800	Weak transcription	HSMMtube	muscle
19	chr18:12724800-12728000	Weak transcription	NHLF	lung
20	chr18:12725000-12727800	Weak transcription	Skeletal Muscle Male	skeletal muscle
21	chr18:12725000-12728600	Weak transcription	Primary T killer memory cells from peripheral blood	blood
22	chr18:12725200-12729600	Weak transcription	Brain Cingulate Gyrus	brain
23	chr18:12725200-12730200	Weak transcription	A549	lung
24	chr18:12725400-12728200	Weak transcription	Colonic Mucosa	Colon
25	chr18:12725400-12729000	Weak transcription	Primary hematopoietic stem cells	blood
26	chr18:12725600-12728000	Weak transcription	NHDF-Ad	bronchial
27	chr18:12725600-12728600	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
28	chr18:12725600-12729400	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
29	chr18:12725600-12729400	Weak transcription	HepG2	liver
30	chr18:12725800-12727400	Strong transcription	IMR90 fetal lung fibroblasts Cell Line	lung
31	chr18:12725800-12727600	Strong transcription	Fetal Stomach	stomach
32	chr18:12725800-12728000	Strong transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
33	chr18:12725800-12729800	Weak transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
34	chr18:12725800-12729800	Weak transcription	Hela-S3	cervix
35	chr18:12726000-12727400	Genic enhancers	Primary hematopoietic stem cells short term culture	blood
36	chr18:12726000-12728000	Weak transcription	Cortex derived primary cultured neurospheres	brain
37	chr18:12726000-12728800	Weak transcription	NH-A	brain
38	chr18:12726200-12728400	Weak transcription	Pancreas	Pancrea
39	chr18:12726200-12729400	Weak transcription	HUES48 Cell Line	embryonic stem cell
40	chr18:12726200-12740400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
41	chr18:12726400-12727400	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
42	chr18:12726600-12728200	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
43	chr18:12726600-12728200	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
44	chr18:12726600-12728200	Weak transcription	Liver	Liver
45	chr18:12726600-12735600	Weak transcription	Right Atrium	heart
46	chr18:12726800-12728400	Weak transcription	Fetal Intestine Large	intestine
47	chr18:12726800-12730200	Weak transcription	HMEC	breast
48	chr18:12727000-12727400	Genic enhancers	Dnd41	blood
49	chr18:12727000-12727400	Enhancers	Osteobl	bone
50	chr18:12727000-12728600	Weak transcription	Duodenum Smooth Muscle	Duodenum

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links