Variant report

Variant	nsv982942
Chromosome Location	chr11:48510979-48901578
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:2750)
CpG islands
(count:61)
Chromatin interactive
region (count:4)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:2750 , 50 per page) page: 1 2 3 4 5 6 7 ... 55

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ARID3A	chr11:48892892-48893269	HepG2	liver:	n/a	n/a
2	ARID3A	chr11:48600198-48600306	K562	blood:	n/a	n/a
3	ARID3A	chr11:48880376-48880748	HepG2	liver:	n/a	n/a
4	ARID3A	chr11:48895975-48896341	HepG2	liver:	n/a	n/a
5	ATF1	chr11:48859189-48859770	K562	blood:	n/a	n/a
6	ATF1	chr11:48849264-48849333	K562	blood:	n/a	n/a
7	ATF1	chr11:48883351-48883720	K562	blood:	n/a	n/a
8	ATF1	chr11:48880374-48880748	K562	blood:	n/a	n/a
9	ATF1	chr11:48796111-48796444	K562	blood:	n/a	n/a
10	ATF1	chr11:48896850-48897050	K562	blood:	n/a	n/a
11	ATF1	chr11:48845364-48845733	K562	blood:	n/a	n/a
12	ATF1	chr11:48867583-48867993	K562	blood:	n/a	n/a
13	ATF1	chr11:48892890-48893270	K562	blood:	n/a	n/a
14	ATF1	chr11:48895825-48896343	K562	blood:	n/a	n/a
15	ATF3	chr11:48845439-48845653	H1-hESC	embryonic stem cell:	n/a	n/a
16	ATF3	chr11:48892858-48893151	H1-hESC	embryonic stem cell:	n/a	n/a
17	BACH1	chr11:48881669-48882080	K562	blood:	n/a	n/a
18	BACH1	chr11:48814467-48814498	K562	blood:	n/a	n/a
19	BATF	chr11:48775372-48775512	GM12878	blood:	n/a	n/a
20	BATF	chr11:48892880-48893156	GM12878	blood:	n/a	n/a
21	BATF	chr11:48831050-48831447	GM12878	blood:	n/a	n/a
22	BATF	chr11:48861796-48862105	GM12878	blood:	n/a	n/a
23	BATF	chr11:48867136-48868238	GM12878	blood:	n/a	n/a
24	BATF	chr11:48817733-48818014	GM12878	blood:	n/a	n/a
25	BATF	chr11:48866749-48866988	GM12878	blood:	n/a	n/a
26	BATF	chr11:48834403-48834545	GM12878	blood:	n/a	n/a
27	BATF	chr11:48887996-48888565	GM12878	blood:	n/a	n/a
28	BATF	chr11:48844664-48844887	GM12878	blood:	n/a	n/a
29	BATF	chr11:48834286-48834608	GM12878	blood:	n/a	n/a
30	BATF	chr11:48856700-48857102	GM12878	blood:	n/a	n/a
31	BATF	chr11:48883213-48883919	GM12878	blood:	n/a	n/a
32	BATF	chr11:48894524-48895290	GM12878	blood:	n/a	n/a
33	BATF	chr11:48888085-48888631	GM12878	blood:	n/a	n/a
34	BATF	chr11:48810469-48810756	GM12878	blood:	n/a	n/a
35	BATF	chr11:48877440-48877803	GM12878	blood:	n/a	n/a
36	BATF	chr11:48844232-48844479	GM12878	blood:	n/a	n/a
37	BATF	chr11:48776572-48776725	GM12878	blood:	n/a	n/a
38	BATF	chr11:48828245-48828584	GM12878	blood:	n/a	n/a
39	BATF	chr11:48776576-48776723	GM12878	blood:	n/a	n/a
40	BATF	chr11:48854637-48855193	GM12878	blood:	n/a	n/a
41	BATF	chr11:48842846-48843034	GM12878	blood:	n/a	n/a
42	BATF	chr11:48895948-48896327	GM12878	blood:	n/a	n/a
43	BATF	chr11:48856704-48856991	GM12878	blood:	n/a	n/a
44	BATF	chr11:48894608-48895288	GM12878	blood:	n/a	n/a
45	BATF	chr11:48895950-48896265	GM12878	blood:	n/a	n/a
46	BATF	chr11:48877878-48878291	GM12878	blood:	n/a	n/a
47	BATF	chr11:48828245-48828541	GM12878	blood:	n/a	n/a
48	BATF	chr11:48886811-48887099	GM12878	blood:	n/a	n/a
49	BATF	chr11:48805015-48805320	GM12878	blood:	n/a	n/a
50	BATF	chr11:48859171-48859730	GM12878	blood:	n/a	n/a

(count:61 , 50 per page) page: 1 2

No.	Chromosome Location	Cell Line	Cell type	Cell Stage
1	chr11:48880009-48880059	SKMC	muscle:	n/a
2	chr11:48880009-48880059	HPAEpiC	pulmonary alveolar:	n/a
3	chr11:48880009-48880059	NHDF-neo	bronchial:	n/a
4	chr11:48880009-48880059	ProgFib	skin:	n/a
5	chr11:48880009-48880059	CMK	blood:	n/a
6	chr11:48880009-48880059	Jurkat	blood:	n/a
7	chr11:48880009-48880059	H1-hESC	embryonic stem cell:	embryo
8	chr11:48880009-48880059	BE2_C	brain:	n/a
9	chr11:48880009-48880059	BJ	skin:	n/a
10	chr11:48880009-48880059	MCF10A-Er-Src	breast:	n/a
11	chr11:48880009-48880059	GM12892	blood:	n/a
12	chr11:48880009-48880059	A549	lung:	n/a
13	chr11:48880009-48880059	ECC-1	luminal epithelium:	n/a
14	chr11:48880009-48880059	SK-N-MC	brain:	n/a
15	chr11:48880009-48880059	GM06990	blood:	n/a
16	chr11:48880009-48880059	HUVEC	blood vessel:	n/a
17	chr11:48880009-48880059	GM12878	blood:	n/a
18	chr11:48880009-48880059	SAEC	small airway:	n/a
19	chr11:48880009-48880059	AG10803	skin:	n/a
20	chr11:48880009-48880059	PANC-1	pancreas:	n/a
21	chr11:48880009-48880059	ovcar-3	ovarian:	n/a
22	chr11:48880009-48880059	SK-N-SH	brain:	n/a
23	chr11:48880009-48880059	HAEpiC	amniotic membrane:	n/a
24	chr11:48880009-48880059	GM19239	blood:	n/a
25	chr11:48880009-48880059	IMR90	lung:	fetal
26	chr11:48880009-48880059	PrEC	prostate:	n/a
27	chr11:48880009-48880059	HCT-116	colon:	n/a
28	chr11:48880009-48880059	HCPEpiC	choroid plexus:	n/a
29	chr11:48880009-48880059	HRCEpiC	kidney:	n/a
30	chr11:48880009-48880059	GM12891	blood:	n/a
31	chr11:48880009-48880059	NH-A	brain:	n/a
32	chr11:48880009-48880059	T-47D	breast:	n/a
33	chr11:48880009-48880059	U87	brain:	n/a
34	chr11:48880009-48880059	HNPCEpiC	eye:	n/a
35	chr11:48880009-48880059	NB4	blood:	n/a
36	chr11:48880009-48880059	AG04450	lung:	fetal
37	chr11:48880009-48880059	AG09309	skin:	n/a
38	chr11:48880009-48880059	AG09319	gingival:	n/a
39	chr11:48880009-48880059	SK-N-SH_RA	brain:	n/a
40	chr11:48880009-48880059	HEEpiC	esophagus:	n/a
41	chr11:48880009-48880059	Hepatocyte	liver:	n/a
42	chr11:48880009-48880059	HCM	heart:	n/a
43	chr11:48880009-48880059	HIPEpiC	eye:	n/a
44	chr11:48880009-48880059	LNCaP	prostate:	n/a
45	chr11:48880009-48880059	HepG2	liver:	n/a
46	chr11:48880009-48880059	K562	blood:	n/a
47	chr11:48880009-48880059	HMEC	breast:	n/a
48	chr11:48880009-48880059	AoSMC	blood vessel:	n/a
49	chr11:48880009-48880059	HCF	heart:	n/a
50	chr11:48880009-48880059	HRE	kidney:	n/a

(count:4 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr11:48811378..48811898-chr8:46850618..46851141,2	MCF-7	breast:
2	chr1:121484040..121484766-chr11:48865024..48865526,2	MCF-7	breast:
3	chr1:121484496..121485051-chr11:48865024..48865528,2	K562	blood:
4	chr11:48862246..48863766-chr12:38036979..38038502,2	MCF-7	breast:

No data

Variant related genes	Relation type
OR4A41P	TF binding region
OR4A40P	TF binding region
OR4A46P	TF binding region
OR4A44P	TF binding region
ENSG00000255551	TF binding region
OR4A45P	TF binding region
OR4A48P	TF binding region
OR4R1P	TF binding region
OR4A42P	TF binding region
OR4A43P	TF binding region
OR4A41P	CpG island
OR4A40P	CpG island
OR4A46P	CpG island
OR4A44P	CpG island
ENSG00000255551	CpG island
OR4A45P	CpG island
OR4A48P	CpG island
OR4R1P	CpG island
OR4A42P	CpG island
OR4A43P	CpG island

Extended variants
information (count: 16094 )
Associated
traits (count: 69 )

Variant overlapped rSNPs/rCNVs (count:16094 , 50 per page) page: 1 2 3 4 5 6 7 ... 322

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs181848663	chr11:48512057-48512058	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
2	rs370397302	chr11:48512118-48512119	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
3	rs7108553	chr11:48512125-48512126	Inactive region	TF binding region	2 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
4	rs368280719	chr11:48512147-48512148	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
5	rs561241986	chr11:48512168-48512169	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
6	rs372024458	chr11:48512171-48512172	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
7	rs186202997	chr11:48512192-48512193	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
8	rs7124853	chr11:48512208-48512209	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
9	rs144680071	chr11:48512235-48512236	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
10	rs538778609	chr11:48512251-48512252	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
11	rs539589777	chr11:48512258-48512259	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
12	rs191053030	chr11:48512265-48512266	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
13	rs538224003	chr11:48512278-48512279	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
14	rs557341174	chr11:48512285-48512286	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
15	rs573991745	chr11:48512291-48512292	Inactive region	TF binding region	2 gene(s)	Overlapped CNVs	n/a
16	rs562441769	chr11:48513920-48513921	Inactive region	TF binding region	1 gene(s)	Overlapped CNVs	n/a
17	rs11039773	chr11:48513931-48513932	Inactive region	TF binding region	1 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
18	rs11039774	chr11:48513959-48513960	Inactive region	TF binding region	1 gene(s)	LD-proxies of rSNP Overlapped rCNV	n/a
19	rs577834227	chr11:48513965-48513966	Inactive region	TF binding region	1 gene(s)	Overlapped CNVs	n/a
20	rs142964506	chr11:48514815-48514816	Inactive region	TF binding region	1 gene(s)	Overlapped CNVs	n/a
21	rs565268660	chr11:48514825-48514826	Inactive region	TF binding region	1 gene(s)	Overlapped CNVs	n/a
22	rs570525856	chr11:48514851-48514852	Inactive region	TF binding region	1 gene(s)	Overlapped CNVs	n/a
23	rs568802959	chr11:48514856-48514857	Inactive region	TF binding region	1 gene(s)	Overlapped CNVs	n/a
24	rs572252690	chr11:48515608-48515609	Enhancers	n/a	n/a	Overlapped CNVs	n/a
25	rs541290971	chr11:48515610-48515611	Enhancers	n/a	n/a	Overlapped CNVs	n/a
26	rs4882089	chr11:48515612-48515613	Enhancers	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
27	rs138144389	chr11:48515632-48515633	Enhancers	n/a	n/a	Overlapped CNVs	n/a
28	rs149569343	chr11:48515638-48515639	Enhancers	n/a	n/a	Overlapped CNVs	n/a
29	rs563370304	chr11:48515647-48515648	Enhancers	n/a	n/a	Overlapped CNVs	n/a
30	rs137904212	chr11:48515665-48515666	Enhancers	n/a	n/a	Overlapped CNVs	n/a
31	rs192673787	chr11:48515697-48515698	Enhancers	n/a	n/a	Overlapped CNVs	n/a
32	rs548713877	chr11:48515712-48515713	Enhancers	n/a	n/a	Overlapped CNVs	n/a
33	rs573793788	chr11:48515769-48515770	Enhancers	n/a	n/a	Overlapped CNVs	n/a
34	rs565626334	chr11:48515782-48515783	Enhancers	n/a	n/a	Overlapped CNVs	n/a
35	rs72902615	chr11:48515818-48515819	Enhancers	n/a	n/a	Overlapped CNVs	n/a
36	rs182737447	chr11:48515820-48515821	Enhancers	n/a	n/a	Overlapped CNVs	n/a
37	rs571773185	chr11:48515830-48515831	Enhancers	n/a	n/a	Overlapped CNVs	n/a
38	rs537242699	chr11:48515927-48515928	Enhancers	n/a	n/a	Overlapped CNVs	n/a
39	rs117105194	chr11:48515978-48515979	Enhancers	n/a	n/a	Overlapped CNVs	n/a
40	rs376994231	chr11:48515980-48515981	Enhancers	n/a	n/a	Overlapped CNVs	n/a
41	rs188257997	chr11:48515982-48515983	Enhancers	n/a	n/a	Overlapped CNVs	n/a
42	rs192716351	chr11:48516005-48516006	Enhancers	n/a	n/a	Overlapped CNVs	n/a
43	rs377295984	chr11:48516024-48516025	Enhancers	n/a	n/a	Overlapped CNVs	n/a
44	rs534644686	chr11:48516048-48516049	Enhancers	n/a	n/a	Overlapped CNVs	n/a
45	rs528503024	chr11:48516052-48516053	Enhancers	n/a	n/a	Overlapped CNVs	n/a
46	rs558010030	chr11:48516056-48516057	Enhancers	n/a	n/a	Overlapped CNVs	n/a
47	rs577959345	chr11:48516065-48516066	Enhancers	n/a	n/a	Overlapped CNVs	n/a
48	rs543633511	chr11:48516103-48516104	Enhancers	n/a	n/a	Overlapped CNVs	n/a
49	rs184201919	chr11:48516112-48516113	Enhancers	n/a	n/a	Overlapped CNVs	n/a
50	rs573784206	chr11:48516122-48516123	Enhancers	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:69)

Disease	PMID	Source
Parathyroid adenoma	22454399	CNVD
Medulloblastoma	21979893	CNVD
Chordoma	21602918	CNVD
Breast cancer	21949216	CNVD
Cancer	21637783	CNVD
Non-syndromic sensorineural hearing loss	19222835	CNVD
T-cell acute lymphoblastic leukemia	20065082	CNVD
Ewing''s sarcoma	21437220	CNVD
Glioblastoma multiforme	21080181	CNVD
Endometrial cancer	22040021	CNVD
Astrocytoma	17387387	CNVD
Breast cancer	21264507	CNVD
Beckwith-Wiedemann syndrome	21518781	CNVD
Wilms tumour	21518781	CNVD
Hepatoblastoma	21518781	CNVD
Acute lymphoblastic leukemia	20067559	CNVD
Gastrointestinal stromal cancer	17535989	CNVD
Paraganglioma	17535989	CNVD
Pulmonary chondroma	17535989	CNVD
Wilms tumour	21544195	CNVD
Gastric cancer	17908304	CNVD
Multiple myeloma	20724749	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
Autism	22495311	CNVD
Chronic lymphocytic leukemia	21546498	CNVD
Non-small cell lung cancer	21385341	CNVD
Intellectual disability	22102821	CNVD
Renal cell carcinoma	18194544	CNVD
Breast cancer	17603634	CNVD
Chordoma	18071362	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Potocki-Shaffer syndrome	19222835	CNVD
WAGR syndrome	19222835	CNVD
Lung cancer	18438408	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Myelofibrosis	22110671	CNVD
Melanoma	18172304	CNVD
Intracranial ependymoma	16609018	CNVD
Myxofibrosarcoma	16751306	CNVD
Potocki-Shaffer syndrome	22470819	CNVD
Neurodevelopmental disorder	22521361	CNVD
Breast cancer	16608533	CNVD
Hirschsprung''s Disease	21712996	CNVD
Follicular lymphoma	20505157	CNVD
Colorectal cancer	21128281	CNVD
Breast cancer	20409316	CNVD
Neurocytoma	17123091	CNVD
Central neurocytomas	17123091	CNVD
Multiple myeloma	16616336	CNVD
Cancer	17160897	CNVD
Mantle cell lymphoma	19029149	CNVD
Glioblastoma multiforme	21138945	CNVD
Breast cancer	21364760	CNVD
Prostate cancer	18632612	CNVD
lymphocytic leukemia	21291569	CNVD
Acute lymphoblastic leukemia	22581003	CNVD
Breast cancer	21990379	CNVD
Acute myeloid leukemia	20729466	CNVD
Non-syndromic sensorineural hearing loss	17122850	CNVD
Schizophrenia	20967226	CNVD
small cell lung cancer	20016488	CNVD
Non-syndromic sensorineural hearing loss	21293372	CNVD
Glioma	20126413	CNVD
Breast cancer	22522925	CNVD
Ovarian clear cell carcinoma	21343371	CNVD
Medulloblastoma	21163964	CNVD
Non-syndromic sensorineural hearing loss	19587683	CNVD
early-passage human iPS cells	21368824	CNVD
Intellectual disability	22045946	CNVD

Chromatin state (count:747 , 50 per page) page: 1 2 3 4 5 6 7 ... 15

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:48515600-48516600	Enhancers	Pancreatic Islets	Pancreatic Islet
2	chr11:48569000-48569600	ZNF genes & repeats	HUES6 Cell Line	embryonic stem cell
3	chr11:48569200-48569600	ZNF genes & repeats	HUES64 Cell Line	embryonic stem cell
4	chr11:48576800-48577000	ZNF genes & repeats	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
5	chr11:48632800-48633200	Active TSS	Fetal Heart	heart
6	chr11:48670600-48672800	ZNF genes & repeats	HUES64 Cell Line	embryonic stem cell
7	chr11:48671600-48672200	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell
8	chr11:48671600-48674000	ZNF genes & repeats	iPS-20b Cell Line	embryonic stem cell
9	chr11:48679800-48680400	ZNF genes & repeats	Adipose Nuclei	Adipose
10	chr11:48680200-48688400	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
11	chr11:48681200-48684000	ZNF genes & repeats	Liver	Liver
12	chr11:48685000-48686400	ZNF genes & repeats	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
13	chr11:48686800-48688000	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell
14	chr11:48688200-48691800	ZNF genes & repeats	HUES64 Cell Line	embryonic stem cell
15	chr11:48694000-48695400	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell
16	chr11:48694200-48695800	ZNF genes & repeats	Adipose Nuclei	Adipose
17	chr11:48695400-48695800	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
18	chr11:48696800-48698200	ZNF genes & repeats	Liver	Liver
19	chr11:48697200-48699000	ZNF genes & repeats	Adipose Nuclei	Adipose
20	chr11:48698200-48698800	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
21	chr11:48704600-48705400	ZNF genes & repeats	Adipose Nuclei	Adipose
22	chr11:48711000-48712200	ZNF genes & repeats	Liver	Liver
23	chr11:48717600-48718400	ZNF genes & repeats	iPS-18 Cell Line	embryonic stem cell
24	chr11:48718000-48718200	ZNF genes & repeats	H9 Cell Line	embryonic stem cell
25	chr11:48718000-48718200	ZNF genes & repeats	Primary T cells effector/memory enriched fromperipheralblood	blood
26	chr11:48718000-48718200	ZNF genes & repeats	HUVEC	blood vessel
27	chr11:48718000-48718200	ZNF genes & repeats	NH-A	brain
28	chr11:48718000-48718400	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell
29	chr11:48718000-48718400	ZNF genes & repeats	Primary hematopoietic stem cells short term culture	blood
30	chr11:48718000-48718600	ZNF genes & repeats	ES-I3 Cell Line	embryonic stem cell
31	chr11:48718000-48719000	ZNF genes & repeats	Adipose Nuclei	Adipose
32	chr11:48718200-48718400	ZNF genes & repeats	Brain Inferior Temporal Lobe	brain
33	chr11:48728000-48728800	ZNF genes & repeats	Liver	Liver
34	chr11:48728400-48728800	ZNF genes & repeats	Duodenum Smooth Muscle	Duodenum
35	chr11:48731000-48732600	ZNF genes & repeats	Liver	Liver
36	chr11:48731400-48733000	ZNF genes & repeats	iPS-20b Cell Line	embryonic stem cell
37	chr11:48731400-48735600	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
38	chr11:48732600-48733400	Weak transcription	Liver	Liver
39	chr11:48733200-48734600	ZNF genes & repeats	HUES64 Cell Line	embryonic stem cell
40	chr11:48733200-48735800	ZNF genes & repeats	HUES48 Cell Line	embryonic stem cell
41	chr11:48733400-48734200	ZNF genes & repeats	Primary T helper cells PMA-I stimulated	--
42	chr11:48733400-48734200	ZNF genes & repeats	Liver	Liver
43	chr11:48733400-48734400	ZNF genes & repeats	Adipose Nuclei	Adipose
44	chr11:48733800-48734200	Active TSS	Right Atrium	heart
45	chr11:48734200-48738400	Weak transcription	Right Atrium	heart
46	chr11:48736600-48742600	ZNF genes & repeats	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
47	chr11:48738000-48739600	ZNF genes & repeats	Adipose Nuclei	Adipose
48	chr11:48738400-48739200	Active TSS	Right Atrium	heart
49	chr11:48738800-48742000	ZNF genes & repeats	Liver	Liver
50	chr11:48741200-48742400	ZNF genes & repeats	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived

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