Variant report

Variant	rs10745270
Chromosome Location	chr10:49554608-49554609
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

Extended variants
information (count: 61 )
Associated
traits (count: 2 )

rSNPs within LD-proxies of this variant (count:56)

rs_ID	r²[population]
rs10218874	0.95[AFR][1000 genomes];0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs10437448	0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs10508903	0.96[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs1051507	0.91[EUR][1000 genomes]
rs1051508	0.91[EUR][1000 genomes]
rs1051509	0.88[EUR][1000 genomes]
rs10745266	0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs10745269	0.90[AFR][1000 genomes];0.94[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs10776595	0.88[AMR][1000 genomes];0.97[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs10776596	0.88[AMR][1000 genomes];0.97[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs10776598	0.94[AFR][1000 genomes];0.99[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs10776600	0.82[EUR][1000 genomes]
rs10857560	0.81[AFR][1000 genomes];0.85[AMR][1000 genomes];0.97[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs10857562	0.80[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs10857566	0.95[EUR][1000 genomes]
rs11101290	0.84[AMR][1000 genomes];0.92[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs11101298	0.87[AFR][1000 genomes];0.91[AMR][1000 genomes];0.88[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs11101306	0.90[AFR][1000 genomes];0.87[AMR][1000 genomes];0.95[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11101317	0.93[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs11101318	0.93[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs11101320	0.93[EUR][1000 genomes]
rs11598434	0.88[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs1345103	0.97[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs1919708	0.88[AMR][1000 genomes];0.97[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs1919712	0.92[ASN][1000 genomes]
rs1919713	0.81[ASN][1000 genomes]
rs2263102	0.96[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs2289805	0.82[ASN][1000 genomes]
rs2463960	0.81[AMR][1000 genomes];0.95[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs2590381	0.83[AMR][1000 genomes];0.96[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs2698761	0.95[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs2698766	0.96[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs2698767	0.92[ASN][1000 genomes]
rs2921271	0.83[ASN][1000 genomes]
rs3789320	0.89[EUR][1000 genomes]
rs3827680	0.93[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs3827681	0.80[EUR][1000 genomes]
rs3950310	0.86[ASN][1000 genomes]
rs4838590	0.96[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs61840543	0.85[ASN][1000 genomes]
rs6537560	0.88[AFR][1000 genomes];0.94[AMR][1000 genomes];0.99[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs6537561	0.88[AMR][1000 genomes];0.97[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs7072515	0.89[AFR][1000 genomes];0.94[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs7075976	0.83[AMR][1000 genomes];0.96[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs7076214	0.81[ASN][1000 genomes]
rs7086070	0.95[AFR][1000 genomes];0.94[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs7086275	0.93[EUR][1000 genomes]
rs7101060	0.89[AFR][1000 genomes];0.92[AMR][1000 genomes];0.98[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs734371	0.83[AMR][1000 genomes];0.96[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7904142	0.93[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs7912697	0.83[ASN][1000 genomes]
rs7924070	0.95[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs8428	0.93[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs867631	0.89[AMR][1000 genomes];0.96[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs883604	0.96[AFR][1000 genomes];0.94[AMR][1000 genomes];0.99[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs9888128	0.93[EUR][1000 genomes];0.86[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:5 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv895366	chr10:49299274-49576454	Enhancers Active TSS Weak transcription Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Strong transcription Bivalent Enhancer Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
2	nsv467190	chr10:49402084-49576878	Flanking Active TSS Enhancers Weak transcription Active TSS Bivalent Enhancer Strong transcription ZNF genes & repeats Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	10 gene(s)	inside rSNPs	diseases
3	nsv550811	chr10:49402084-49576878	Weak transcription Enhancers Active TSS Flanking Active TSS Bivalent/Poised TSS Bivalent Enhancer Genic enhancers Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	10 gene(s)	inside rSNPs	diseases
4	nsv895371	chr10:49492075-50232180	Weak transcription Active TSS Bivalent Enhancer Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	35 gene(s)	inside rSNPs	diseases
5	nsv6587	chr10:49526329-49571804	Weak transcription Genic enhancers Enhancers ZNF genes & repeats Flanking Active TSS Active TSS Strong transcription	Chromatin interactive region lncRNA	3 gene(s)	inside rSNPs	diseases

mRNA abundance (count:2)

SNP	Gene	Cis/trans	Tissue	Source
rs10745270	MAPK8	Cis_1M	lymphoblastoid	RTeQTL
rs10745270	MAPK8	cis	Thyroid	GTEx

Chromatin state (count:20 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:49516400-49559600	Weak transcription	Rectal Smooth Muscle	rectum
2	chr10:49539200-49555000	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
3	chr10:49541200-49559400	Weak transcription	Fetal Lung	lung
4	chr10:49542800-49568000	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
5	chr10:49543000-49576200	Weak transcription	Right Atrium	heart
6	chr10:49543200-49554800	Weak transcription	Breast Myoepithelial Primary Cells	Breast
7	chr10:49543200-49554800	Weak transcription	Primary hematopoietic stem cells short term culture	blood
8	chr10:49545800-49555800	Weak transcription	Primary T cells from cord blood	blood
9	chr10:49549000-49557000	Weak transcription	HSMMtube	muscle
10	chr10:49549200-49555200	Weak transcription	Dnd41	blood
11	chr10:49550400-49560800	Weak transcription	Psoas Muscle	Psoas
12	chr10:49552200-49555400	Weak transcription	Pancreatic Islets	Pancreatic Islet
13	chr10:49552400-49555200	Weak transcription	iPS-20b Cell Line	embryonic stem cell
14	chr10:49552600-49554800	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
15	chr10:49552600-49556600	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
16	chr10:49552600-49558200	Weak transcription	Skeletal Muscle Female	skeletal muscle
17	chr10:49552600-49568800	Weak transcription	NHDF-Ad	bronchial
18	chr10:49553800-49555800	ZNF genes & repeats	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
19	chr10:49554000-49555200	Enhancers	Left Ventricle	heart
20	chr10:49554600-49554800	ZNF genes & repeats	Primary hematopoietic stem cells G-CSF-mobilized Male	--

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