Variant report

Variant	rs10840098
Chromosome Location	chr11:8666976-8666977
allele	C/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr11:8666699..8668669-chr11:8675245..8676830,2	K562	blood:
2	chr11:8653441..8656999-chr11:8666272..8669350,3	K562	blood:
3	chr11:8665915..8667503-chr11:8668333..8670297,2	K562	blood:

Variant related genes	Relation type
ENSG00000166436	Chromatin interaction

Extended variants
information (count: 7 )
Associated
traits (count: 6 )

rSNPs within LD-proxies of this variant (count:5)

rs_ID	r²[population]
rs10769917	0.84[AMR][1000 genomes]
rs10840101	1.00[AFR][1000 genomes];0.99[AMR][1000 genomes];0.96[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs10840103	0.96[ASN][1000 genomes]
rs11042032	1.00[ASN][1000 genomes]
rs11605978	0.97[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv2751035	chr11:8431654-8685451	Strong transcription Weak transcription Enhancers ZNF genes & repeats Genic enhancers Flanking Active TSS Bivalent/Poised TSS Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
2	nsv896983	chr11:8526643-8682465	ZNF genes & repeats Strong transcription Weak transcription Bivalent Enhancer Flanking Active TSS Enhancers Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases

mRNA abundance (count:6)

SNP	Gene	Cis/trans	Tissue	Source
rs10840098	LOC256273	Cis_1M	lymphoblastoid	RTeQTL
rs10840098	TRIM66	cis	lung	GTEx
rs10840098	TRIM66	cis	Muscle Skeletal	GTEx
rs10840098	TRIM66	cis	Whole Blood	GTEx
rs10840098	TRIM66	cis	Heart Left Ventricle	GTEx
rs10840098	TRIM66	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:121 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:8637000-8703200	Weak transcription	Small Intestine	intestine
2	chr11:8644800-8667000	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
3	chr11:8646200-8671000	Weak transcription	HUVEC	blood vessel
4	chr11:8650800-8676200	Strong transcription	Monocytes-CD14+_RO01746	blood
5	chr11:8652200-8675000	Strong transcription	Primary monocytes fromperipheralblood	blood
6	chr11:8653400-8667000	Weak transcription	Rectal Smooth Muscle	rectum
7	chr11:8654000-8673800	Strong transcription	Primary B cells from peripheral blood	blood
8	chr11:8654200-8673800	Strong transcription	Primary T helper cells fromperipheralblood	blood
9	chr11:8654200-8675600	Strong transcription	Stomach Smooth Muscle	stomach
10	chr11:8654400-8672400	Strong transcription	Brain Anterior Caudate	brain
11	chr11:8655000-8670200	Strong transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
12	chr11:8655000-8676400	Strong transcription	Primary T cells from cord blood	blood
13	chr11:8655200-8672600	Strong transcription	Primary mononuclear cells fromperipheralblood	Blood
14	chr11:8655400-8673400	Strong transcription	Dnd41	blood
15	chr11:8655600-8670600	Strong transcription	Adipose Nuclei	Adipose
16	chr11:8656000-8670600	Strong transcription	Fetal Muscle Leg	muscle
17	chr11:8656000-8672600	Strong transcription	Skeletal Muscle Female	skeletal muscle
18	chr11:8656000-8672800	Strong transcription	Placenta	Placenta
19	chr11:8656600-8671600	Strong transcription	Brain Cingulate Gyrus	brain
20	chr11:8657200-8673800	Strong transcription	Primary neutrophils fromperipheralblood	blood
21	chr11:8657400-8672600	Strong transcription	Primary T regulatory cells fromperipheralblood	blood
22	chr11:8658000-8675200	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
23	chr11:8658200-8672400	Strong transcription	Primary hematopoietic stem cells short term culture	blood
24	chr11:8658200-8673800	Strong transcription	Primary T helper naive cells fromperipheralblood	blood
25	chr11:8658400-8671200	Strong transcription	Primary T helper cells PMA-I stimulated	--
26	chr11:8658400-8671600	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
27	chr11:8658600-8673000	Strong transcription	Fetal Adrenal Gland	Adrenal Gland
28	chr11:8658600-8674200	Strong transcription	Primary T cells fromperipheralblood	blood
29	chr11:8658600-8675000	Strong transcription	Liver	Liver
30	chr11:8659200-8670400	Strong transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
31	chr11:8659200-8673600	Weak transcription	Colon Smooth Muscle	Colon
32	chr11:8659400-8669000	Weak transcription	Primary T helper naive cells from peripheral blood	blood
33	chr11:8660000-8667200	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
34	chr11:8660000-8667400	Weak transcription	HSMMtube	muscle
35	chr11:8660000-8669200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
36	chr11:8660200-8671000	Weak transcription	NHDF-Ad	bronchial
37	chr11:8660400-8667200	Weak transcription	NH-A	brain
38	chr11:8660400-8669200	Weak transcription	Colonic Mucosa	Colon
39	chr11:8660400-8670200	Strong transcription	Foreskin Fibroblast Primary Cells skin02	Skin
40	chr11:8660800-8670800	Strong transcription	IMR90 fetal lung fibroblasts Cell Line	lung
41	chr11:8661200-8667600	Strong transcription	Esophagus	oesophagus
42	chr11:8661800-8673600	Weak transcription	Pancreatic Islets	Pancreatic Islet
43	chr11:8662400-8667200	Weak transcription	Gastric	stomach
44	chr11:8662400-8669800	Strong transcription	Foreskin Fibroblast Primary Cells skin01	Skin
45	chr11:8662400-8670200	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
46	chr11:8662600-8667000	Weak transcription	Spleen	Spleen
47	chr11:8662600-8667200	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
48	chr11:8662600-8669000	Weak transcription	Right Ventricle	heart
49	chr11:8662600-8680200	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
50	chr11:8662600-8692000	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived

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