Variant report

Variant	rs10898448
Chromosome Location	chr11:85947751-85947752
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr11:85946291..85947955-chr11:85950332..85952940,2	MCF-7	breast:
2	chr11:85947523..85949171-chr11:85949297..85951177,2	K562	blood:
3	chr11:85945851..85950710-chr11:85953305..85957322,5	K562	blood:
4	chr11:85946401..85949010-chr11:85954753..85956671,4	MCF-7	breast:
5	chr11:85775759..85778337-chr11:85946507..85948966,2	K562	blood:
6	chr11:85945638..85949163-chr11:85954268..85958718,6	K562	blood:

Variant related genes	Relation type
ENSG00000074266	Chromatin interaction

Extended variants
information (count: 31 )
Associated
traits (count: 2 )

rSNPs within LD-proxies of this variant (count:28)

rs_ID	r²[population]
rs10751137	0.85[ASN][1000 genomes]
rs10792841	0.84[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs10792842	0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs10792843	0.85[ASN][1000 genomes]
rs10898449	0.89[AMR][1000 genomes];0.97[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs10898452	0.84[EUR][1000 genomes]
rs10898457	0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs10898458	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11234594	0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11234596	0.83[ASN][1000 genomes]
rs12284085	0.88[AFR][1000 genomes];0.82[AMR][1000 genomes];0.83[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs1466804	0.84[EUR][1000 genomes]
rs1497725	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.83[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs1497726	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.84[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs1874694	0.81[AMR][1000 genomes];0.84[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs2270680	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.83[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs2270681	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.85[ASN][1000 genomes]
rs3758881	0.84[ASN][1000 genomes]
rs7101712	0.85[ASN][1000 genomes]
rs7120070	0.82[AMR][1000 genomes];0.83[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7120222	0.86[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7924472	0.93[ASN][1000 genomes]
rs7942971	0.84[EUR][1000 genomes]
rs7950820	0.90[AFR][1000 genomes];0.82[AMR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7951030	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7951188	0.91[AFR][1000 genomes];0.82[AMR][1000 genomes];0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs974144	0.84[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs991435	0.85[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1050948	chr11:85756325-85968665	Active TSS Genic enhancers Transcr. at gene 5' and 3' Enhancers Flanking Active TSS Weak transcription Strong transcription Bivalent/Poised TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	43 gene(s)	inside rSNPs	diseases
2	nsv541117	chr11:85756325-85968665	Enhancers Weak transcription Flanking Active TSS Active TSS Transcr. at gene 5' and 3' Strong transcription Bivalent/Poised TSS Bivalent Enhancer Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	43 gene(s)	inside rSNPs	diseases
3	nsv832223	chr11:85845315-86015957	Enhancers Weak transcription Active TSS Flanking Active TSS Strong transcription Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	36 gene(s)	inside rSNPs	diseases

mRNA abundance (count:2)

SNP	Gene	Cis/trans	Tissue	Source
rs10898448	EED	Cis_1M	lymphoblastoid	RTeQTL
rs10898448	C11orf73	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:3 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:85941600-85955000	Weak transcription	ES-I3 Cell Line	embryonic stem cell
2	chr11:85946200-85949200	Enhancers	K562	blood
3	chr11:85947400-85948800	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived

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