Variant report

Variant	rs149085963
Chromosome Location	chr14:65170616-65170617
allele	A/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	TCF12	chr14:65170555-65172728	A549	lung:	n/a	chr14:65172656-65172666 chr14:65171088-65171096
2	CHD1	chr14:65170208-65171187	H1-hESC	embryonic stem cell:	n/a	n/a
3	ZBTB7A	chr14:65170572-65172154	ECC-1	luminal epithelium:	n/a	n/a
4	MYC	chr14:65170454-65170796	MCF10A-Er-Src	breast:	n/a	n/a
5	MXI1	chr14:65170555-65171559	H1-hESC	embryonic stem cell:	n/a	n/a
6	HA-E2F1	chr14:65169675-65172166	MCF-7	breast:	n/a	chr14:65171866-65171881 chr14:65170968-65170978 chr14:65172102-65172109 chr14:65169782-65169791
7	SIN3AK20	chr14:65169607-65171579	HCT-116	colon:	n/a	n/a
8	FOXM1	chr14:65169581-65171381	ECC-1	luminal epithelium:	n/a	n/a
9	NR2F2	chr14:65170570-65171844	MCF-7	breast:	n/a	n/a
10	MAX	chr14:65170439-65173969	A549	lung:	n/a	chr14:65173325-65173341 chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
11	MAX	chr14:65170495-65172967	A549	lung:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
12	MAX	chr14:65170580-65172620	ECC-1	luminal epithelium:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
13	MYC	chr14:65170015-65171235	MCF10A-Er-Src	breast:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
14	GATA3	chr14:65170555-65171637	A549	lung:	n/a	chr14:65171452-65171462 chr14:65171453-65171462 chr14:65171453-65171460 chr14:65171453-65171460 chr14:65171453-65171460 chr14:65171446-65171467 chr14:65170574-65170585
15	POLR2A	chr14:65170612-65170621	H1-hESC	embryonic stem cell:	n/a	n/a
16	TAF1	chr14:65170521-65171315	H1-hESC	embryonic stem cell:	n/a	n/a
17	MAX	chr14:65170560-65170937	H1-hESC	embryonic stem cell:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
18	E2F6	chr14:65170546-65171462	H1-hESC	embryonic stem cell:	n/a	chr14:65170968-65170978
19	STAT3	chr14:65170412-65170665	MCF10A-Er-Src	breast:	n/a	n/a
20	POLR2A	chr14:65170456-65171992	H1-neurons	neurons:	n/a	n/a
21	MAX	chr14:65170539-65171616	H1-hESC	embryonic stem cell:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
22	GATA3	chr14:65170544-65171122	T-47D	breast:	n/a	chr14:65170574-65170585
23	MYC	chr14:65170431-65171637	A549	lung:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
24	KAP1	chr14:65170604-65171015	HEK293	kidney:	n/a	n/a
25	SIN3A	chr14:65169247-65172845	H1-hESC	embryonic stem cell:	n/a	chr14:65170757-65170768 chr14:65171026-65171039 chr14:65171772-65171781
26	MAX	chr14:65170463-65171579	HCT-116	colon:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
27	POLR2A	chr14:65170346-65171617	H1-hESC	embryonic stem cell:	n/a	n/a
28	E2F6	chr14:65170589-65172869	A549	lung:	n/a	chr14:65171866-65171881 chr14:65170968-65170978 chr14:65172102-65172109
29	MAX	chr14:65170373-65172927	HCT-116	colon:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
30	HDAC2	chr14:65170555-65172570	MCF-7	breast:	n/a	chr14:65171648-65171662 chr14:65171652-65171666
31	TAF1	chr14:65170493-65172096	ECC-1	luminal epithelium:	n/a	n/a
32	MAX	chr14:65170468-65172596	ECC-1	luminal epithelium:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
33	MAX	chr14:65170610-65171416	SK-N-SH	brain:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
34	EP300	chr14:65169537-65172188	ECC-1	luminal epithelium:	n/a	chr14:65170968-65170977 chr14:65171022-65171031
35	CTBP2	chr14:65170588-65172889	H1-hESC	embryonic stem cell:	n/a	n/a
36	CREB1	chr14:65170592-65171724	HepG2	liver:	n/a	n/a
37	MAX	chr14:65170576-65171726	H1-hESC	embryonic stem cell:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
38	POLR2A	chr14:65169213-65172105	ECC-1	luminal epithelium:	n/a	n/a
39	POLR2A	chr14:65170484-65171721	H1-neurons	neurons:	n/a	n/a
40	MAX	chr14:65170509-65172661	HepG2	liver:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
41	SIN3AK20	chr14:65170514-65171640	H1-hESC	embryonic stem cell:	n/a	n/a
42	TEAD4	chr14:65170565-65171354	H1-hESC	embryonic stem cell:	n/a	n/a
43	MAX	chr14:65169786-65172685	MCF-7	breast:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882
44	TCF12	chr14:65170552-65171532	ECC-1	luminal epithelium:	n/a	chr14:65171088-65171096
45	REST	chr14:65170225-65172797	H1-neurons	neurons:	n/a	chr14:65171938-65171948
46	SP1	chr14:65170552-65171385	A549	lung:	n/a	chr14:65170759-65170773
47	ELF1	chr14:65170534-65173200	MCF-7	breast:	n/a	chr14:65170695-65170707 chr14:65171838-65171847 chr14:65170967-65170976 chr14:65170969-65170981 chr14:65170773-65170785 chr14:65171019-65171031 chr14:65171480-65171492
48	POLR2A	chr14:65169627-65171518	ECC-1	luminal epithelium:	n/a	n/a
49	MXI1	chr14:65170022-65172720	SK-N-SH	brain:	n/a	n/a
50	MAX	chr14:65170512-65172711	MCF-7	breast:	n/a	chr14:65170873-65170883 chr14:65170874-65170881 chr14:65170869-65170884 chr14:65170873-65170882

No.	Chromosome Location	Cell Line	Cell type	Cell Stage
1	chr14:65170569-65170619	HPAEpiC	pulmonary alveolar:	n/a
2	chr14:65170569-65170619	U87	brain:	n/a
3	chr14:65170569-65170619	HepG2	liver:	n/a
4	chr14:65170569-65170619	HEEpiC	esophagus:	n/a
5	chr14:65170569-65170619	AG10803	skin:	n/a
6	chr14:65170569-65170619	GM06990	blood:	n/a
7	chr14:65170569-65170619	NHBE	bronchial:	n/a
8	chr14:65170569-65170619	PrEC	prostate:	n/a
9	chr14:65170569-65170619	NH-A	brain:	n/a
10	chr14:65170569-65170619	NT2-D1	testis:	n/a
11	chr14:65170569-65170619	AoSMC	blood vessel:	n/a
12	chr14:65170569-65170619	MCF10A-Er-Src	breast:	n/a
13	chr14:65170569-65170619	SK-N-MC	brain:	n/a
14	chr14:65170569-65170619	HRPEpiC	eye:	n/a
15	chr14:65170569-65170619	SKMC	muscle:	n/a
16	chr14:65170569-65170619	ovcar-3	ovarian:	n/a
17	chr14:65170569-65170619	AG09309	skin:	n/a
18	chr14:65170569-65170619	HIPEpiC	eye:	n/a
19	chr14:65170569-65170619	GM19239	blood:	n/a
20	chr14:65170569-65170619	AG04449	skin:	fetal
21	chr14:65170569-65170619	T-47D	breast:	n/a
22	chr14:65170569-65170619	HL-60	blood:	n/a
23	chr14:65170569-65170619	HCM	heart:	n/a
24	chr14:65170569-65170619	MCF-7	breast:	n/a
25	chr14:65170569-65170619	HCF	heart:	n/a
26	chr14:65170569-65170619	Hela-S3	cervix:	n/a
27	chr14:65170569-65170619	GM12878	blood:	n/a
28	chr14:65170569-65170619	PANC-1	pancreas:	n/a
29	chr14:65170569-65170619	SK-N-SH	brain:	n/a
30	chr14:65170569-65170619	SAEC	small airway:	n/a
31	chr14:65170569-65170619	HCT-116	colon:	n/a
32	chr14:65170569-65170619	HAEpiC	amniotic membrane:	n/a
33	chr14:65170569-65170619	LNCaP	prostate:	n/a
34	chr14:65170569-65170619	ECC-1	luminal epithelium:	n/a
35	chr14:65170569-65170619	K562	blood:	n/a
36	chr14:65170569-65170619	Caco-2	colon:	n/a
37	chr14:65170569-65170619	BE2_C	brain:	n/a
38	chr14:65170569-65170619	GM12891	blood:	n/a
39	chr14:65170569-65170619	HEK293	kidney:	embryo
40	chr14:65170569-65170619	H1-hESC	embryonic stem cell:	embryo
41	chr14:65170569-65170619	HNPCEpiC	eye:	n/a
42	chr14:65170569-65170619	CMK	blood:	n/a
43	chr14:65170569-65170619	HUVEC	blood vessel:	n/a
44	chr14:65170569-65170619	ProgFib	skin:	n/a
45	chr14:65170569-65170619	Hepatocyte	liver:	n/a
46	chr14:65170569-65170619	RPTEC	kidney:	n/a
47	chr14:65170569-65170619	AG09319	gingival:	n/a
48	chr14:65170569-65170619	AG04450	lung:	fetal
49	chr14:65170569-65170619	SK-N-SH_RA	brain:	n/a
50	chr14:65170569-65170619	HCPEpiC	choroid plexus:	n/a

No.	Distal block	Cell Line	Cell type
1	chr14:64968210..64972351-chr14:65168934..65172584,5	MCF-7	breast:
2	chr14:65168373..65176902-chr14:65220182..65231670,21	MCF-7	breast:
3	chr10:75910632..75911387-chr14:65170334..65171284,2	HCT-116	colon:
4	chr14:65168529..65178400-chr14:65179583..65195815,52	MCF-7	breast:
5	chr14:65170433..65175465-chr14:65207632..65214317,8	MCF-7	breast:
6	chr14:65168335..65178043-chr14:65220677..65234710,31	MCF-7	breast:
7	chr14:64968319..64971699-chr14:65168654..65172546,5	MCF-7	breast:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-SPTB-1	chr14:65170511-65170621	XLOC_011052

Variant related genes	Relation type
PLEKHG3	TF binding region
PLEKHG3	CpG island
ENSG00000126804	Chromatin interaction
ENSG00000185009	Chromatin interaction
ENSG00000126822	Chromatin interaction
ENSG00000089775	Chromatin interaction
ENSG00000156110	Chromatin interaction
ENSG00000070182	Chromatin interaction

Extended variants
information (count: 2 )
Associated
traits (count: 0)

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1049097	chr14:65027753-65202018	Weak transcription Strong transcription Enhancers Genic enhancers Transcr. at gene 5' and 3' Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh ZNF genes & repeats Active TSS Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	21 gene(s)	inside rSNPs	diseases
2	esv3437023	chr14:65170024-65173072	Enhancers Flanking Active TSS Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Weak transcription Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	9 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:123 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:65169000-65170800	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
2	chr14:65169200-65171200	Flanking Active TSS	Foreskin Keratinocyte Primary Cells skin02	Skin
3	chr14:65169200-65172600	Active TSS	ES-WA7 Cell Line	embryonic stem cell
4	chr14:65169400-65170800	Flanking Active TSS	Primary neutrophils fromperipheralblood	blood
5	chr14:65169400-65170800	Enhancers	Lung	lung
6	chr14:65169400-65171000	Flanking Active TSS	Duodenum Mucosa	Duodenum
7	chr14:65169400-65171000	Flanking Active TSS	HMEC	breast
8	chr14:65169400-65172600	Active TSS	H9 Cell Line	embryonic stem cell
9	chr14:65169600-65170800	Active TSS	iPS DF 19.11 Cell Line	embryonic stem cell
10	chr14:65169600-65170800	Flanking Active TSS	Primary T helper memory cells from peripheral blood 2	blood
11	chr14:65169600-65170800	Flanking Active TSS	Primary T helper memory cells from peripheral blood 1	blood
12	chr14:65169600-65170800	Flanking Active TSS	Placenta	Placenta
13	chr14:65169600-65171000	Flanking Bivalent TSS/Enh	Primary T cells from cord blood	blood
14	chr14:65169600-65171000	Flanking Bivalent TSS/Enh	Primary T regulatory cells fromperipheralblood	blood
15	chr14:65169600-65171000	Flanking Active TSS	Fetal Intestine Large	intestine
16	chr14:65169600-65171000	Flanking Active TSS	Fetal Intestine Small	intestine
17	chr14:65169600-65171000	Flanking Active TSS	NHEK	skin
18	chr14:65169600-65171200	Active TSS	ES-I3 Cell Line	embryonic stem cell
19	chr14:65169600-65171400	Bivalent Enhancer	Primary B cells from peripheral blood	blood
20	chr14:65169600-65172200	Active TSS	iPS DF 6.9 Cell Line	embryonic stem cell
21	chr14:65169800-65170800	Flanking Active TSS	Primary T helper 17 cells PMA-I stimulated	--
22	chr14:65169800-65170800	Flanking Bivalent TSS/Enh	HepG2	liver
23	chr14:65169800-65171000	Flanking Bivalent TSS/Enh	Primary T helper cells fromperipheralblood	blood
24	chr14:65169800-65171200	Flanking Bivalent TSS/Enh	Primary T cells fromperipheralblood	blood
25	chr14:65169800-65172200	Active TSS	H1 Cell Line	embryonic stem cell
26	chr14:65169800-65172200	Active TSS	HUES6 Cell Line	embryonic stem cell
27	chr14:65169800-65172400	Active TSS	HUES48 Cell Line	embryonic stem cell
28	chr14:65169800-65172600	Flanking Bivalent TSS/Enh	Monocytes-CD14+_RO01746	blood
29	chr14:65169800-65173600	Flanking Active TSS	Primary B cells from cord blood	blood
30	chr14:65170000-65170800	Flanking Active TSS	Brain Hippocampus Middle	brain
31	chr14:65170000-65170800	Flanking Active TSS	Fetal Heart	heart
32	chr14:65170000-65171000	Flanking Active TSS	Primary T cells effector/memory enriched fromperipheralblood	blood
33	chr14:65170000-65171200	Flanking Bivalent TSS/Enh	Primary T helper cells PMA-I stimulated	--
34	chr14:65170000-65172600	Active TSS	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
35	chr14:65170000-65176600	Flanking Active TSS	Primary hematopoietic stem cells short term culture	blood
36	chr14:65170200-65170800	Flanking Bivalent TSS/Enh	HUES64 Cell Line	embryonic stem cell
37	chr14:65170200-65170800	Flanking Bivalent TSS/Enh	Primary hematopoietic stem cells	blood
38	chr14:65170200-65170800	Flanking Active TSS	Placenta Amnion	Placenta Amnion
39	chr14:65170200-65170800	Flanking Active TSS	Rectal Smooth Muscle	rectum
40	chr14:65170200-65171000	Flanking Active TSS	Breast Myoepithelial Primary Cells	Breast
41	chr14:65170200-65171000	Flanking Active TSS	Primary Natural Killer cells fromperipheralblood	blood
42	chr14:65170200-65171000	Flanking Active TSS	Adipose Nuclei	Adipose
43	chr14:65170200-65171000	Flanking Active TSS	Brain Anterior Caudate	brain
44	chr14:65170200-65171000	Flanking Bivalent TSS/Enh	Fetal Adrenal Gland	Adrenal Gland
45	chr14:65170200-65171000	Flanking Active TSS	Rectal Mucosa Donor 29	rectum
46	chr14:65170200-65171000	Flanking Active TSS	Rectal Mucosa Donor 31	rectum
47	chr14:65170200-65171000	Enhancers	Sigmoid Colon	Sigmoid Colon
48	chr14:65170200-65172200	Active TSS	Small Intestine	intestine
49	chr14:65170200-65172600	Active TSS	Pancreatic Islets	Pancreatic Islet
50	chr14:65170400-65170800	Flanking Bivalent TSS/Enh	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links