Variant report

Variant	rs16869303
Chromosome Location	chr8:103252839-103252840
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	STAT3	chr8:103252728-103252974	MCF10A-Er-Src	breast:	n/a	n/a
2	FOS	chr8:103252703-103252999	MCF10A-Er-Src	breast:	n/a	chr8:103252915-103252923 chr8:103252914-103252925
3	MYC	chr8:103250944-103252930	MCF10A-Er-Src	breast:	n/a	chr8:103252521-103252530 chr8:103252519-103252532 chr8:103252520-103252531 chr8:103252519-103252532 chr8:103252520-103252530 chr8:103252519-103252532 chr8:103252520-103252531 chr8:103252520-103252530 chr8:103252520-103252531
4	FOS	chr8:103252685-103253012	MCF10A-Er-Src	breast:	n/a	chr8:103252915-103252923 chr8:103252914-103252925
5	STAT3	chr8:103252737-103252971	MCF10A-Er-Src	breast:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr8:101732898..101734475-chr8:103251086..103253067,2	K562	blood:
2	chr8:103251457..103253123-chr8:103664713..103667608,2	K562	blood:
3	chr8:103251288..103253851-chr8:103665938..103668117,3	MCF-7	breast:
4	chr8:103250357..103253420-chr8:103818570..103821747,5	MCF-7	breast:
5	chr8:102504608..102506883-chr8:103249593..103253284,4	MCF-7	breast:
6	chr8:103251275..103253446-chr8:103664809..103667608,3	K562	blood:
7	chr8:103249647..103255113-chr8:103258766..103269094,16	K562	blood:
8	chr8:103251230..103254364-chr8:103817398..103821115,5	K562	blood:
9	chr8:103250463..103253576-chr8:103253593..103260199,5	K562	blood:
10	chr8:103250631..103253167-chr8:103267124..103270074,2	K562	blood:
11	chr8:103252256..103253981-chr8:103422815..103425571,2	MCF-7	breast:

Variant related genes	Relation type
RRM2B	TF binding region
ENSG00000246263	TF binding region
ENSG00000272037	Chromatin interaction
ENSG00000083307	Chromatin interaction
ENSG00000254024	Chromatin interaction
ENSG00000155090	Chromatin interaction
ENSG00000253328	Chromatin interaction
ENSG00000253669	Chromatin interaction
ENSG00000104517	Chromatin interaction
ENSG00000246263	Chromatin interaction
ENSG00000070756	Chromatin interaction

Extended variants
information (count: 11 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:1)

rs_ID	r²[population]
rs10505021	0.96[AFR][1000 genomes];1.00[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:10 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1020359	chr8:103109921-103318415	Weak transcription Flanking Active TSS Enhancers Strong transcription Active TSS Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	21 gene(s)	inside rSNPs	diseases
2	nsv1033829	chr8:103110057-103525696	Strong transcription Flanking Active TSS Enhancers Weak transcription ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Bivalent Enhancer Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	37 gene(s)	inside rSNPs	diseases
3	nsv1021459	chr8:103163436-103401754	Weak transcription Enhancers Flanking Active TSS Strong transcription Active TSS Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	24 gene(s)	inside rSNPs	diseases
4	nsv539701	chr8:103163436-103401754	Strong transcription Enhancers Weak transcription Flanking Active TSS ZNF genes & repeats Transcr. at gene 5' and 3' Genic enhancers Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	24 gene(s)	inside rSNPs	diseases
5	nsv1025935	chr8:103199207-103468322	Strong transcription Weak transcription Enhancers Genic enhancers Flanking Active TSS ZNF genes & repeats Transcr. at gene 5' and 3' Active TSS Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	35 gene(s)	inside rSNPs	diseases
6	nsv1018990	chr8:103207922-103357742	Genic enhancers Strong transcription Flanking Active TSS Weak transcription Enhancers Active TSS Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	19 gene(s)	inside rSNPs	diseases
7	nsv539702	chr8:103207922-103357742	Strong transcription Weak transcription Enhancers Flanking Active TSS Active TSS Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	19 gene(s)	inside rSNPs	diseases
8	nsv1028890	chr8:103207922-103401754	Weak transcription Genic enhancers Active TSS Enhancers Strong transcription ZNF genes & repeats Flanking Active TSS Transcr. at gene 5' and 3' Bivalent/Poised TSS Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	22 gene(s)	inside rSNPs	diseases
9	nsv891242	chr8:103210971-103282418	Weak transcription Strong transcription Enhancers Flanking Active TSS Active TSS Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	19 gene(s)	inside rSNPs	diseases
10	nsv891243	chr8:103219629-103292724	Weak transcription Enhancers Flanking Active TSS Strong transcription Genic enhancers ZNF genes & repeats Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	19 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:109 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr8:103249600-103253200	Active TSS	H9 Cell Line	embryonic stem cell
2	chr8:103250600-103253400	Active TSS	Rectal Mucosa Donor 29	rectum
3	chr8:103252000-103268400	Weak transcription	Small Intestine	intestine
4	chr8:103252200-103253000	Flanking Active TSS	Primary neutrophils fromperipheralblood	blood
5	chr8:103252200-103253000	Flanking Active TSS	Primary B cells from cord blood	blood
6	chr8:103252200-103253000	Flanking Active TSS	Primary hematopoietic stem cells	blood
7	chr8:103252200-103253000	Flanking Active TSS	GM12878-XiMat	blood
8	chr8:103252200-103253000	Flanking Active TSS	K562	blood
9	chr8:103252200-103253400	Flanking Active TSS	Primary hematopoietic stem cells short term culture	blood
10	chr8:103252200-103253600	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Female	--
11	chr8:103252200-103253800	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
12	chr8:103252200-103263000	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
13	chr8:103252200-103268800	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
14	chr8:103252200-103269400	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
15	chr8:103252200-103273600	Weak transcription	Esophagus	oesophagus
16	chr8:103252200-103273600	Weak transcription	Spleen	Spleen
17	chr8:103252200-103273800	Weak transcription	Lung	lung
18	chr8:103252200-103292800	Weak transcription	Gastric	stomach
19	chr8:103252200-103318800	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
20	chr8:103252400-103253000	Enhancers	NH-A	brain
21	chr8:103252400-103260200	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
22	chr8:103252400-103262400	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
23	chr8:103252400-103263000	Weak transcription	Fetal Thymus	thymus
24	chr8:103252400-103263200	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
25	chr8:103252400-103263200	Weak transcription	Placenta	Placenta
26	chr8:103252400-103263400	Weak transcription	Primary T cells fromperipheralblood	blood
27	chr8:103252400-103263400	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
28	chr8:103252400-103263800	Weak transcription	H1 Cell Line	embryonic stem cell
29	chr8:103252400-103265000	Weak transcription	Fetal Muscle Trunk	muscle
30	chr8:103252400-103265200	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
31	chr8:103252400-103266200	Weak transcription	Brain Angular Gyrus	brain
32	chr8:103252400-103266200	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
33	chr8:103252400-103266200	Weak transcription	Left Ventricle	heart
34	chr8:103252400-103266200	Weak transcription	HSMMtube	muscle
35	chr8:103252400-103268800	Weak transcription	Fetal Muscle Leg	muscle
36	chr8:103252400-103269200	Weak transcription	Placenta Amnion	Placenta Amnion
37	chr8:103252400-103271800	Weak transcription	Right Ventricle	heart
38	chr8:103252400-103272000	Weak transcription	Fetal Stomach	stomach
39	chr8:103252400-103273800	Weak transcription	Pancreas	Pancrea
40	chr8:103252400-103276000	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
41	chr8:103252400-103280200	Weak transcription	Aorta	Aorta
42	chr8:103252400-103292400	Weak transcription	Psoas Muscle	Psoas
43	chr8:103252600-103253000	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
44	chr8:103252600-103253000	Enhancers	Brain Anterior Caudate	brain
45	chr8:103252600-103253000	Enhancers	Brain Dorsolateral Prefrontal Cortex	brain
46	chr8:103252600-103253000	Enhancers	Fetal Intestine Large	intestine
47	chr8:103252600-103253000	Enhancers	HMEC	breast
48	chr8:103252600-103253200	Weak transcription	Sigmoid Colon	Sigmoid Colon
49	chr8:103252600-103253200	Enhancers	Stomach Smooth Muscle	stomach
50	chr8:103252600-103253400	Enhancers	Primary B cells from peripheral blood	blood

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links