Variant report

Variant	rs17881354
Chromosome Location	chr7:100494202-100494203
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	ATF3	chr7:100494168-100494495	K562	blood:	n/a	n/a
2	ETS1	chr7:100494102-100495052	K562	blood:	n/a	n/a
3	BHLHE40	chr7:100493664-100494277	K562	blood:	n/a	n/a
4	CEBPB	chr7:100494141-100494478	K562	blood:	n/a	n/a
5	TBP	chr7:100494164-100494523	K562	blood:	n/a	n/a
6	JUN	chr7:100493191-100496118	K562	blood:	n/a	chr7:100494328-100494341 chr7:100493521-100493530
7	TEAD4	chr7:100493666-100494337	K562	blood:	n/a	n/a
8	MAX	chr7:100493689-100494367	H1-hESC	embryonic stem cell:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
9	CTCF	chr7:100493591-100495920	SK-N-SH	brain:	n/a	chr7:100494903-100494919 chr7:100494902-100494920 chr7:100494902-100494915 chr7:100494142-100494151 chr7:100494905-100494918 chr7:100494905-100494918 chr7:100494904-100494925
10	CTCF	chr7:100494200-100494350	GM12867	blood:	n/a	n/a
11	MAX	chr7:100493550-100494585	ECC-1	luminal epithelium:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
12	CEBPB	chr7:100494149-100494482	HepG2	liver:	n/a	n/a
13	GABPA	chr7:100493590-100494380	K562	blood:	n/a	n/a
14	NR2F2	chr7:100493577-100494443	K562	blood:	n/a	n/a
15	RCOR1	chr7:100493759-100494365	K562	blood:	n/a	n/a
16	MYC	chr7:100493631-100495749	K562	blood:	n/a	chr7:100493756-100493765 chr7:100494831-100494840 chr7:100493755-100493766
17	GTF2F1	chr7:100494055-100494502	K562	blood:	n/a	n/a
18	CTCF	chr7:100494160-100494310	SAEC	small airway:	n/a	n/a
19	MTA3	chr7:100493734-100494322	GM12878	blood:	n/a	n/a
20	CEBPB	chr7:100494120-100494419	K562	blood:	n/a	n/a
21	HMGN3	chr7:100492415-100495041	K562	blood:	n/a	n/a
22	ZBTB7A	chr7:100492182-100495231	K562	blood:	n/a	n/a
23	POLR2A	chr7:100493562-100495029	H1-neurons	neurons:	n/a	n/a
24	MAX	chr7:100493658-100494577	H1-hESC	embryonic stem cell:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
25	MAX	chr7:100493587-100495235	K562	blood:	n/a	chr7:100493756-100493765 chr7:100494831-100494840 chr7:100493755-100493766
26	E2F6	chr7:100493618-100495225	K562	blood:	n/a	n/a
27	BACH1	chr7:100493709-100495065	H1-hESC	embryonic stem cell:	n/a	n/a
28	MAX	chr7:100493602-100494613	H1-hESC	embryonic stem cell:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
29	HDAC2	chr7:100493594-100494566	K562	blood:	n/a	n/a
30	POLR2A	chr7:100494036-100494618	K562	blood:	n/a	n/a
31	ZBTB7A	chr7:100493557-100494629	K562	blood:	n/a	n/a
32	MAX	chr7:100493443-100494663	MCF-7	breast:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
33	ATF2	chr7:100494017-100494492	H1-hESC	embryonic stem cell:	n/a	n/a
34	MAX	chr7:100493568-100496026	K562	blood:	n/a	chr7:100493756-100493765 chr7:100494831-100494840 chr7:100493755-100493766
35	HDAC2	chr7:100492345-100495320	MCF-7	breast:	n/a	n/a
36	REST	chr7:100494119-100495027	H1-neurons	neurons:	n/a	n/a
37	CTCF	chr7:100494140-100494290	AG09319	gingival:	n/a	chr7:100494142-100494151
38	EP300	chr7:100494170-100494352	K562	blood:	n/a	n/a
39	CTBP2	chr7:100493682-100494302	H1-hESC	embryonic stem cell:	n/a	n/a
40	POLR2A	chr7:100493578-100495127	H1-neurons	neurons:	n/a	n/a
41	NR2F2	chr7:100493578-100494530	K562	blood:	n/a	n/a
42	CCNT2	chr7:100492094-100495029	K562	blood:	n/a	chr7:100492742-100492751
43	JUN	chr7:100494199-100494356	HepG2	liver:	n/a	chr7:100494328-100494341
44	E2F6	chr7:100494135-100494557	H1-hESC	embryonic stem cell:	n/a	n/a
45	MAX	chr7:100493569-100494574	K562	blood:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
46	MAX	chr7:100493572-100494630	A549	lung:	n/a	chr7:100493756-100493765 chr7:100493755-100493766
47	HDAC2	chr7:100493544-100494646	K562	blood:	n/a	n/a
48	MYC	chr7:100493573-100495803	K562	blood:	n/a	chr7:100493756-100493765 chr7:100494831-100494840 chr7:100493755-100493766
49	MAX	chr7:100493572-100495417	A549	lung:	n/a	chr7:100493756-100493765 chr7:100494831-100494840 chr7:100493755-100493766
50	SETDB1	chr7:100493784-100494517	K562	blood:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr7:100494043..100496246-chr7:100550371..100552219,2	K562	blood:
2	chr7:100491420..100497264-chr7:100607951..100612175,9	K562	blood:
3	chr7:100493649..100495175-chr7:100549463..100550982,2	MCF-7	breast:
4	chr7:100491799..100497264-chr7:100607837..100612175,9	K562	blood:
5	chr7:100493490..100497118-chr7:100701265..100703603,3	K562	blood:
6	chr7:100026330..100028591-chr7:100493941..100496922,3	K562	blood:
7	chr7:100270007..100272523-chr7:100492882..100494851,2	K562	blood:
8	chr7:100492344..100495062-chr7:100726871..100729209,3	MCF-7	breast:
9	chr7:100026330..100028332-chr7:100493941..100495752,2	K562	blood:
10	chr7:100491373..100494455-chr7:100609680..100612292,3	MCF-7	breast:
11	chr7:100491924..100495059-chr7:100886100..100889819,5	MCF-7	breast:
12	chr7:100492733..100496183-chr7:100699112..100703676,5	MCF-7	breast:
13	chr7:100491458..100494589-chr7:100859109..100862606,4	MCF-7	breast:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-ACHE-2	chr7:100494174-100494594	NONHSAT122422

Variant related genes	Relation type
ACHE	TF binding region
ENSG00000222636	Chromatin interaction
ENSG00000169871	Chromatin interaction
ENSG00000106397	Chromatin interaction
ENSG00000172354	Chromatin interaction
ENSG00000078487	Chromatin interaction
ENSG00000146834	Chromatin interaction
ENSG00000106400	Chromatin interaction
ENSG00000214253	Chromatin interaction
ENSG00000169894	Chromatin interaction
ENSG00000225946	Chromatin interaction

Extended variants
information (count: 33 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:6)

rs_ID	r²[population]
rs11973842	1.00[AMR][1000 genomes]
rs11974682	1.00[AMR][1000 genomes]
rs17228609	1.00[AMR][1000 genomes]
rs17881553	1.00[AMR][1000 genomes]
rs2405977	1.00[ASW][hapmap]
rs61746950	1.00[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:27 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1020837	chr7:100313122-100508635	Genic enhancers Weak transcription Active TSS Strong transcription Enhancers Bivalent Enhancer Flanking Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	92 gene(s)	inside rSNPs	diseases
2	esv1832517	chr7:100355490-100749246	Strong transcription Active TSS Flanking Active TSS Genic enhancers Bivalent Enhancer Enhancers Weak transcription Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	96 gene(s)	inside rSNPs	diseases
3	esv2758125	chr7:100355490-100749246	Genic enhancers Weak transcription Transcr. at gene 5' and 3' Bivalent Enhancer Active TSS ZNF genes & repeats Enhancers Strong transcription Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	96 gene(s)	inside rSNPs	diseases
4	esv2759547	chr7:100355490-100749246	Active TSS Weak transcription Genic enhancers Flanking Bivalent TSS/Enh Flanking Active TSS Strong transcription Enhancers Transcr. at gene 5' and 3' Bivalent Enhancer ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	96 gene(s)	inside rSNPs	diseases
5	nsv464647	chr7:100374087-100497131	Flanking Active TSS Strong transcription Bivalent/Poised TSS Genic enhancers Enhancers Weak transcription Bivalent Enhancer Active TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	90 gene(s)	inside rSNPs	diseases
6	nsv607965	chr7:100374087-100497131	Bivalent Enhancer Transcr. at gene 5' and 3' Bivalent/Poised TSS Genic enhancers Active TSS Flanking Active TSS Weak transcription Strong transcription Enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	90 gene(s)	inside rSNPs	diseases
7	nsv1032673	chr7:100382250-100606794	Enhancers Weak transcription Genic enhancers Flanking Active TSS Transcr. at gene 5' and 3' Strong transcription Active TSS Bivalent Enhancer ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	92 gene(s)	inside rSNPs	diseases
8	nsv888799	chr7:100406144-100497131	Enhancers Bivalent Enhancer Active TSS Weak transcription Genic enhancers Strong transcription Flanking Active TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	89 gene(s)	inside rSNPs	diseases
9	nsv888801	chr7:100416250-100497131	Active TSS Enhancers Genic enhancers Weak transcription Transcr. at gene 5' and 3' Strong transcription Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	89 gene(s)	inside rSNPs	diseases
10	nsv464648	chr7:100422156-100518458	Enhancers Strong transcription Genic enhancers Bivalent/Poised TSS Weak transcription Flanking Active TSS Transcr. at gene 5' and 3' Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	90 gene(s)	inside rSNPs	diseases
11	nsv607966	chr7:100422156-100518458	Enhancers Active TSS Weak transcription Genic enhancers Flanking Active TSS Strong transcription Bivalent/Poised TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	90 gene(s)	inside rSNPs	diseases
12	nsv831073	chr7:100425659-100544888	Bivalent Enhancer Enhancers Flanking Active TSS Transcr. at gene 5' and 3' Weak transcription Strong transcription Active TSS Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	88 gene(s)	inside rSNPs	diseases
13	nsv888802	chr7:100484917-100495530	Bivalent/Poised TSS Flanking Active TSS Bivalent Enhancer Enhancers Genic enhancers Flanking Bivalent TSS/Enh Active TSS Transcr. at gene 5' and 3' Strong transcription Weak transcription	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	39 gene(s)	inside rSNPs	diseases
14	nsv888803	chr7:100486656-100497131	Flanking Bivalent TSS/Enh Active TSS Flanking Active TSS Bivalent Enhancer Weak transcription Bivalent/Poised TSS Transcr. at gene 5' and 3' Enhancers Genic enhancers Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
15	nsv888804	chr7:100486754-100494202	Active TSS Transcr. at gene 5' and 3' Bivalent Enhancer Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Weak transcription Genic enhancers Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
16	nsv888805	chr7:100486754-100498057	Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Weak transcription Enhancers Active TSS Transcr. at gene 5' and 3' Bivalent Enhancer Genic enhancers Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
17	nsv888806	chr7:100488407-100495530	Bivalent Enhancer Flanking Bivalent TSS/Enh Enhancers Active TSS Genic enhancers Bivalent/Poised TSS Weak transcription Flanking Active TSS Transcr. at gene 5' and 3' Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	27 gene(s)	inside rSNPs	diseases
18	nsv888807	chr7:100490077-100498057	Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Flanking Active TSS Enhancers Genic enhancers Active TSS Weak transcription Transcr. at gene 5' and 3' Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	15 gene(s)	inside rSNPs	diseases
19	nsv888808	chr7:100490981-100498057	Bivalent Enhancer Enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Active TSS Weak transcription Flanking Active TSS Transcr. at gene 5' and 3' Genic enhancers Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	13 gene(s)	inside rSNPs	diseases
20	nsv888809	chr7:100491451-100495530	Flanking Active TSS Bivalent Enhancer Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Weak transcription Enhancers Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
21	nsv888810	chr7:100492127-100495530	Weak transcription Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Enhancers Bivalent Enhancer Flanking Active TSS Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
22	nsv888811	chr7:100492127-100497131	Bivalent/Poised TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Active TSS Genic enhancers Enhancers Weak transcription Flanking Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
23	nsv888812	chr7:100492127-100498057	Flanking Bivalent TSS/Enh Active TSS Flanking Active TSS Bivalent Enhancer Bivalent/Poised TSS Enhancers Weak transcription Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
24	nsv888813	chr7:100492322-100495530	Flanking Bivalent TSS/Enh Flanking Active TSS Active TSS Bivalent Enhancer Enhancers Bivalent/Poised TSS Weak transcription Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
25	nsv888814	chr7:100492357-100495530	Bivalent Enhancer Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS Enhancers Flanking Active TSS Weak transcription Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases
26	nsv888815	chr7:100492357-100497131	Flanking Bivalent TSS/Enh Active TSS Bivalent Enhancer Bivalent/Poised TSS Weak transcription Enhancers Flanking Active TSS Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases
27	nsv607970	chr7:100492493-100494949	Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Bivalent Enhancer Active TSS Enhancers Weak transcription Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:112 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr7:100491800-100495000	Bivalent/Poised TSS	HUES64 Cell Line	embryonic stem cell
2	chr7:100492200-100495000	Bivalent/Poised TSS	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
3	chr7:100492400-100494400	Active TSS	Psoas Muscle	Psoas
4	chr7:100492600-100495000	Flanking Bivalent TSS/Enh	Primary hematopoietic stem cells G-CSF-mobilized Male	--
5	chr7:100493000-100494600	Bivalent/Poised TSS	HUES48 Cell Line	embryonic stem cell
6	chr7:100493200-100494400	Bivalent Enhancer	Primary hematopoietic stem cells short term culture	blood
7	chr7:100493400-100494800	Bivalent Enhancer	Placenta Amnion	Placenta Amnion
8	chr7:100493400-100494800	Bivalent Enhancer	HMEC	breast
9	chr7:100493400-100495200	Bivalent Enhancer	Primary T helper memory cells from peripheral blood 1	blood
10	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Primary neutrophils fromperipheralblood	blood
11	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Primary T helper naive cells fromperipheralblood	blood
12	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Primary T helper cells PMA-I stimulated	--
13	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Primary T helper cells fromperipheralblood	blood
14	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Duodenum Mucosa	Duodenum
15	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Fetal Brain Female	brain
16	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Fetal Intestine Large	intestine
17	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Fetal Stomach	stomach
18	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Rectal Mucosa Donor 31	rectum
19	chr7:100493600-100494400	Flanking Bivalent TSS/Enh	Skeletal Muscle Male	skeletal muscle
20	chr7:100493600-100494400	Flanking Active TSS	K562	blood
21	chr7:100493600-100494400	Bivalent Enhancer	NHDF-Ad	bronchial
22	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	iPS DF 19.11 Cell Line	embryonic stem cell
23	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Breast Myoepithelial Primary Cells	Breast
24	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Primary B cells from cord blood	blood
25	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Primary T regulatory cells fromperipheralblood	blood
26	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Adipose Nuclei	Adipose
27	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Colonic Mucosa	Colon
28	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Fetal Intestine Small	intestine
29	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Rectal Mucosa Donor 29	rectum
30	chr7:100493600-100494600	Flanking Bivalent TSS/Enh	Stomach Smooth Muscle	stomach
31	chr7:100493600-100495200	Bivalent/Poised TSS	HSMM	muscle
32	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	ES-I3 Cell Line	embryonic stem cell
33	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	HUES6 Cell Line	embryonic stem cell
34	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	iPS-18 Cell Line	embryonic stem cell
35	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	Primary T cells from cord blood	blood
36	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	Primary T helper memory cells from peripheral blood 2	blood
37	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	Primary T helper 17 cells PMA-I stimulated	--
38	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	Primary T cells effector/memory enriched fromperipheralblood	blood
39	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	Brain Cingulate Gyrus	brain
40	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	Duodenum Smooth Muscle	Duodenum
41	chr7:100493800-100494400	Enhancers	Ovary	ovary
42	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	A549	lung
43	chr7:100493800-100494400	Flanking Bivalent TSS/Enh	HepG2	liver
44	chr7:100493800-100494600	Bivalent Enhancer	IMR90 fetal lung fibroblasts Cell Line	lung
45	chr7:100493800-100494600	Flanking Bivalent TSS/Enh	Foreskin Fibroblast Primary Cells skin02	Skin
46	chr7:100493800-100494600	Flanking Bivalent TSS/Enh	Foreskin Keratinocyte Primary Cells skin02	Skin
47	chr7:100493800-100494600	Flanking Bivalent TSS/Enh	Foreskin Melanocyte Primary Cells skin01	Skin
48	chr7:100493800-100494600	Flanking Bivalent TSS/Enh	Monocytes-CD14+_RO01746	blood
49	chr7:100493800-100495000	Flanking Bivalent TSS/Enh	Primary hematopoietic stem cells	blood
50	chr7:100493800-100495200	Bivalent Enhancer	Placenta	Placenta

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