Variant report

Variant	rs2741727
Chromosome Location	chr14:21455438-21455439
allele	A/C
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	JUND	chr14:21455034-21455466	A549	lung:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
2	GATA3	chr14:21454930-21455532	MCF-7	breast:	n/a	chr14:21455229-21455238 chr14:21455151-21455158
3	JUND	chr14:21454803-21455572	SK-N-SH	brain:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
4	JUND	chr14:21454958-21455441	Hela-S3	cervix:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
5	FOSL2	chr14:21454925-21455526	MCF-7	breast:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
6	FOSL1	chr14:21454949-21455503	HCT-116	colon:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
7	JUND	chr14:21454876-21455535	HCT-116	colon:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
8	FOS	chr14:21454971-21455456	MCF10A-Er-Src	breast:	n/a	chr14:21455208-21455219 chr14:21455226-21455237 chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
9	FOSL2	chr14:21454873-21455469	A549	lung:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
10	JUND	chr14:21454955-21455453	SK-N-SH	brain:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
11	FOSL1	chr14:21454845-21455545	HCT-116	colon:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
12	FOS	chr14:21454924-21455524	MCF10A-Er-Src	breast:	n/a	chr14:21455208-21455219 chr14:21455226-21455237 chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
13	JUN	chr14:21454618-21455553	K562	blood:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
14	FOSL2	chr14:21454959-21455492	SK-N-SH	brain:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
15	FOS	chr14:21454926-21455475	MCF10A-Er-Src	breast:	n/a	chr14:21455208-21455219 chr14:21455226-21455237 chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
16	JUND	chr14:21454881-21455547	HCT-116	colon:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
17	JUND	chr14:21454919-21455600	MCF-7	breast:	n/a	chr14:21455231-21455238 chr14:21455226-21455237 chr14:21455226-21455238 chr14:21455208-21455219 chr14:21455228-21455236 chr14:21455229-21455240
18	FOSL2	chr14:21454934-21455499	MCF-7	breast:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
19	FOSL2	chr14:21454864-21455476	SK-N-SH	brain:	n/a	chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240
20	FOS	chr14:21454964-21455650	HUVEC	blood vessel:	n/a	chr14:21455208-21455219 chr14:21455226-21455237 chr14:21455231-21455238 chr14:21455226-21455238 chr14:21455228-21455236 chr14:21455229-21455240

No.	Distal block	Cell Line	Cell type
1	chr14:20920787..20923218-chr14:21454532..21456112,2	MCF-7	breast:
2	chr14:21454547..21456911-chr14:21472680..21474390,2	MCF-7	breast:
3	chr14:21345187..21348103-chr14:21455224..21457829,2	K562	blood:
4	chr14:21454398..21456867-chr14:21465877..21467429,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000258599	TF binding region
METTL17	TF binding region
ENSG00000258471	Chromatin interaction
ENSG00000092094	Chromatin interaction
ENSG00000165794	Chromatin interaction

Extended variants
information (count: 21 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:9)

rs_ID	r²[population]
rs2256677	0.80[EUR][1000 genomes]
rs2741729	0.90[ASN][1000 genomes]
rs2741732	0.88[ASN][1000 genomes]
rs2771334	0.94[AMR][1000 genomes];0.96[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs2771335	0.94[AMR][1000 genomes];0.96[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs2771340	0.91[ASN][1000 genomes]
rs2771342	0.90[ASN][1000 genomes]
rs2771346	0.87[ASN][1000 genomes]
rs2783786	0.91[EUR][1000 genomes];0.95[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:12 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv2758349	chr14:21216108-21471614	Active TSS Flanking Active TSS Enhancers Bivalent Enhancer ZNF genes & repeats Weak transcription Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers Strong transcription Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	41 gene(s)	inside rSNPs	diseases
2	esv2759972	chr14:21216108-21471614	Weak transcription Enhancers Genic enhancers Flanking Active TSS Active TSS Strong transcription Bivalent/Poised TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	41 gene(s)	inside rSNPs	diseases
3	nsv427936	chr14:21216108-21531783	Flanking Active TSS Active TSS Weak transcription Enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS Bivalent Enhancer Strong transcription Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	50 gene(s)	inside rSNPs	diseases
4	nsv428293	chr14:21216108-21531783	Enhancers Flanking Active TSS Weak transcription Genic enhancers Flanking Bivalent TSS/Enh Active TSS Strong transcription Bivalent Enhancer Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	50 gene(s)	inside rSNPs	diseases
5	nsv832740	chr14:21332060-21545052	Enhancers Weak transcription Flanking Active TSS Strong transcription Genic enhancers Bivalent Enhancer Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	45 gene(s)	inside rSNPs	diseases
6	nsv1044554	chr14:21334087-21456092	Enhancers Flanking Active TSS Active TSS Weak transcription Bivalent/Poised TSS Bivalent Enhancer Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	20 gene(s)	inside rSNPs	diseases
7	nsv470622	chr14:21338824-21469151	Enhancers Active TSS Weak transcription Bivalent/Poised TSS Flanking Active TSS Flanking Bivalent TSS/Enh Strong transcription Transcr. at gene 5' and 3' Bivalent Enhancer Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	31 gene(s)	inside rSNPs	diseases
8	nsv563847	chr14:21338824-21469151	Strong transcription Enhancers Weak transcription Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh Genic enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	31 gene(s)	inside rSNPs	diseases
9	nsv530009	chr14:21377022-22044608	Weak transcription Flanking Active TSS Transcr. at gene 5' and 3' Strong transcription Genic enhancers Enhancers Flanking Bivalent TSS/Enh Active TSS Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	111 gene(s)	inside rSNPs	diseases
10	nsv530769	chr14:21407536-22139126	Bivalent/Poised TSS Bivalent Enhancer Strong transcription Active TSS Weak transcription Enhancers Genic enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	117 gene(s)	inside rSNPs	diseases
11	nsv901475	chr14:21426282-21465489	Flanking Bivalent TSS/Enh Weak transcription Genic enhancers Active TSS Strong transcription Enhancers Flanking Active TSS Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	22 gene(s)	inside rSNPs	diseases
12	nsv1054126	chr14:21432455-21456092	Active TSS Flanking Active TSS Enhancers Weak transcription Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	10 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:36 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:21451800-21456600	Weak transcription	Fetal Intestine Small	intestine
2	chr14:21453000-21457600	Enhancers	Primary monocytes fromperipheralblood	blood
3	chr14:21454200-21456600	Weak transcription	Primary hematopoietic stem cells short term culture	blood
4	chr14:21454200-21457400	Weak transcription	Primary neutrophils fromperipheralblood	blood
5	chr14:21454200-21457800	Enhancers	Placenta Amnion	Placenta Amnion
6	chr14:21454400-21455800	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
7	chr14:21454400-21455800	Enhancers	Muscle Satellite Cultured Cells	--
8	chr14:21454400-21456000	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
9	chr14:21454400-21456200	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
10	chr14:21454400-21456400	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
11	chr14:21454400-21456400	Enhancers	NHEK	skin
12	chr14:21454400-21456800	Enhancers	Hela-S3	cervix
13	chr14:21454400-21457200	Enhancers	NH-A	brain
14	chr14:21454400-21457400	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
15	chr14:21454400-21457400	Enhancers	HMEC	breast
16	chr14:21454600-21455600	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
17	chr14:21454600-21455800	Enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
18	chr14:21454600-21455800	Enhancers	Foreskin Fibroblast Primary Cells skin02	Skin
19	chr14:21454600-21455800	Enhancers	Fetal Adrenal Gland	Adrenal Gland
20	chr14:21454600-21456000	Enhancers	NHDF-Ad	bronchial
21	chr14:21454600-21456200	Enhancers	K562	blood
22	chr14:21454600-21456200	Enhancers	NHLF	lung
23	chr14:21454600-21457000	Enhancers	Breast Myoepithelial Primary Cells	Breast
24	chr14:21454600-21457200	Enhancers	Foreskin Fibroblast Primary Cells skin01	Skin
25	chr14:21454600-21457400	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
26	chr14:21454800-21455800	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
27	chr14:21454800-21456000	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
28	chr14:21454800-21456200	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
29	chr14:21455000-21455600	Enhancers	Osteobl	bone
30	chr14:21455000-21456400	Weak transcription	Placenta	Placenta
31	chr14:21455000-21457200	Weak transcription	Ovary	ovary
32	chr14:21455000-21457200	Weak transcription	HSMMtube	muscle
33	chr14:21455200-21456800	Enhancers	Monocytes-CD14+_RO01746	blood
34	chr14:21455400-21456400	Enhancers	A549	lung
35	chr14:21455400-21457000	Weak transcription	HUVEC	blood vessel
36	chr14:21455400-21457200	Weak transcription	HSMM	muscle

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links