Variant report

Variant	rs3746983
Chromosome Location	chr21:46711940-46711941
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	CTCF	chr21:46711545-46711961	K562	blood:	n/a	n/a
2	POLR2A	chr21:46711880-46711958	MCF-7	breast:	n/a	n/a
3	CTCF	chr21:46711940-46712090	GM12878	blood:	n/a	n/a
4	ELF1	chr21:46711840-46712854	MCF-7	breast:	n/a	chr21:46712446-46712459
5	POLR2A	chr21:46711008-46713419	HepG2	liver:	n/a	n/a
6	POLR2A	chr21:46711574-46712104	PANC-1	pancreas:	n/a	n/a
7	MAZ	chr21:46711859-46716395	IMR90	lung:	n/a	chr21:46712242-46712251 chr21:46713452-46713461 chr21:46713786-46713795 chr21:46712241-46712251 chr21:46712243-46712250 chr21:46713453-46713460 chr21:46713784-46713792 chr21:46712241-46712252 chr21:46712242-46712251
8	POLR2A	chr21:46711829-46715303	MCF10A-Er-Src	breast:	n/a	n/a
9	POLR2A	chr21:46707503-46717614	IMR90	lung:	n/a	n/a
10	POLR2A	chr21:46711624-46712839	SK-N-MC	brain:	n/a	n/a
11	CTCF	chr21:46711447-46713112	SK-N-SH	brain:	n/a	chr21:46712746-46712759 chr21:46712551-46712572 chr21:46712549-46712567 chr21:46712917-46712926 chr21:46712552-46712565 chr21:46712259-46712272
12	POLR2A	chr21:46711708-46713222	Hela-S3	cervix:	n/a	n/a
13	POLR2A	chr21:46711759-46712137	MCF-7	breast:	n/a	n/a
14	SMC3	chr21:46711915-46713122	SK-N-SH	brain:	n/a	chr21:46712262-46712272 chr21:46712551-46712565 chr21:46712258-46712272
15	POLR2A	chr21:46711325-46712192	MCF-7	breast:	n/a	n/a
16	POLR2A	chr21:46711705-46712719	MCF10A-Er-Src	breast:	n/a	n/a
17	POLR2A	chr21:46710733-46712159	K562	blood:	n/a	n/a
18	POLR2A	chr21:46709026-46713498	K562	blood:	n/a	n/a
19	POLR2A	chr21:46711758-46712849	HUVEC	blood vessel:	n/a	n/a
20	POLR2A	chr21:46711764-46713002	SK-N-SH	brain:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr21:46709668..46712311-chr21:46829490..46833095,3	MCF-7	breast:
2	chr21:46710906..46714348-chr21:46821217..46828800,8	MCF-7	breast:
3	chr21:46711273..46715306-chr21:46820522..46825546,4	MCF-7	breast:
4	chr21:46710943..46713565-chr21:46960523..46963682,3	K562	blood:
5	chr21:46711169..46713506-chr21:46798030..46799980,2	MCF-7	breast:
6	chr21:46704364..46706493-chr21:46711035..46712601,2	K562	blood:
7	chr21:46710943..46713565-chr21:46960523..46962462,2	K562	blood:
8	chr21:46711496..46712142-chr21:46775912..46776862,2	K562	blood:
9	chr21:46711457..46713560-chr21:46924492..46926024,2	K562	blood:
10	chr21:46706857..46709577-chr21:46709955..46714044,8	K562	blood:
11	chr21:46707421..46709618-chr21:46710328..46714044,7	K562	blood:
12	chr21:46710891..46712493-chr21:46728925..46730569,2	K562	blood:
13	chr21:46560176..46562017-chr21:46709945..46712448,2	MCF-7	breast:
14	chr21:46709020..46713873-chr21:46844930..46849148,6	MCF-7	breast:

No.	lncRNA name	Chromosome Location	lncRNA alias
1	lnc-ADARB1-3	chr21:46710386-46713437	XLOC_013981
2	lnc-ADARB1-3	chr21:46710386-46713437	XLOC_013981
3	lnc-ADARB1-3	chr21:46710386-46713437	XLOC_013981
4	lnc-ADARB1-3	chr21:46710386-46717269	NONHSAT082933
5	lnc-ADARB1-3	chr21:46710386-46717268	XLOC_013981

Variant related genes	Relation type
LINC00205	TF binding region
POFUT2	TF binding region
ENSG00000228355	Chromatin interaction
ENSG00000173638	Chromatin interaction
ENSG00000182871	Chromatin interaction
ENSG00000186866	Chromatin interaction
ENSG00000215447	Chromatin interaction
ENSG00000183535	Chromatin interaction
ENSG00000224574	Chromatin interaction

Extended variants
information (count: 37 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:1)

rs_ID	r²[population]
rs4819053	0.88[AFR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:36 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv531546	chr21:46504151-47411772	Weak transcription Flanking Bivalent TSS/Enh Enhancers Bivalent Enhancer Active TSS Flanking Active TSS Genic enhancers Bivalent/Poised TSS Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	93 gene(s)	inside rSNPs	diseases
2	nsv1059771	chr21:46561482-46830602	Enhancers Flanking Active TSS Weak transcription Bivalent Enhancer Flanking Bivalent TSS/Enh Strong transcription Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent/Poised TSS Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
3	nsv544481	chr21:46561482-46830602	Weak transcription Strong transcription Flanking Active TSS Enhancers Active TSS Bivalent Enhancer ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
4	nsv1063943	chr21:46571988-46819424	Flanking Active TSS Strong transcription Active TSS Enhancers Weak transcription Bivalent Enhancer ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent/Poised TSS Genic enhancers Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	47 gene(s)	inside rSNPs	diseases
5	nsv544482	chr21:46571988-46819424	Strong transcription Enhancers Weak transcription ZNF genes & repeats Genic enhancers Bivalent Enhancer Flanking Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	47 gene(s)	inside rSNPs	diseases
6	nsv1064859	chr21:46571988-46830602	Weak transcription Enhancers Strong transcription Active TSS Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent Enhancer Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
7	nsv544483	chr21:46571988-46830602	ZNF genes & repeats Enhancers Weak transcription Strong transcription Active TSS Flanking Active TSS Bivalent Enhancer Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
8	nsv1061691	chr21:46572641-46831862	Enhancers Active TSS Weak transcription Flanking Bivalent TSS/Enh Strong transcription Bivalent Enhancer Flanking Active TSS ZNF genes & repeats Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
9	nsv544484	chr21:46572641-46831862	Transcr. at gene 5' and 3' ZNF genes & repeats Flanking Active TSS Weak transcription Enhancers Flanking Bivalent TSS/Enh Active TSS Bivalent Enhancer Strong transcription Bivalent/Poised TSS Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
10	nsv587839	chr21:46580370-46837709	Weak transcription Genic enhancers Enhancers Flanking Active TSS Active TSS Strong transcription ZNF genes & repeats Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
11	nsv587840	chr21:46580370-46839904	Bivalent Enhancer Active TSS Enhancers Strong transcription Flanking Active TSS Weak transcription Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	53 gene(s)	inside rSNPs	diseases
12	nsv916959	chr21:46585681-46831845	Bivalent Enhancer Weak transcription Enhancers Active TSS Flanking Active TSS Strong transcription Genic enhancers Bivalent/Poised TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
13	nsv1063721	chr21:46610599-46907894	Active TSS Enhancers Bivalent Enhancer Strong transcription Weak transcription Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	58 gene(s)	inside rSNPs	diseases
14	nsv1059779	chr21:46611859-46891352	Enhancers Weak transcription Flanking Active TSS Bivalent Enhancer Active TSS Strong transcription Bivalent/Poised TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
15	nsv544485	chr21:46611859-46891352	Enhancers Weak transcription Flanking Active TSS Genic enhancers Bivalent Enhancer Strong transcription Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
16	nsv1059805	chr21:46618210-46736943	Weak transcription Genic enhancers Strong transcription Enhancers Flanking Active TSS ZNF genes & repeats Bivalent Enhancer Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	27 gene(s)	inside rSNPs	diseases
17	nsv913999	chr21:46636844-46765251	Bivalent Enhancer Weak transcription Enhancers Genic enhancers Flanking Active TSS Active TSS Strong transcription ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	43 gene(s)	inside rSNPs	diseases
18	nsv914000	chr21:46647078-46765251	Enhancers Weak transcription Strong transcription Flanking Active TSS Genic enhancers Active TSS Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	42 gene(s)	inside rSNPs	diseases
19	nsv914001	chr21:46647078-46944113	Flanking Bivalent TSS/Enh Weak transcription Bivalent Enhancer Enhancers Flanking Active TSS ZNF genes & repeats Genic enhancers Strong transcription Active TSS Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	57 gene(s)	inside rSNPs	diseases
20	nsv914002	chr21:46655638-46945024	Enhancers Strong transcription Weak transcription Active TSS Bivalent Enhancer Flanking Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	57 gene(s)	inside rSNPs	diseases
21	nsv1057807	chr21:46656346-47077374	Weak transcription Enhancers Active TSS Flanking Active TSS Transcr. at gene 5' and 3' Bivalent Enhancer Strong transcription ZNF genes & repeats Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA	70 gene(s)	inside rSNPs	diseases
22	nsv914004	chr21:46670874-46736694	Enhancers Strong transcription Active TSS Weak transcription Bivalent/Poised TSS Flanking Active TSS Genic enhancers ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	25 gene(s)	inside rSNPs	diseases
23	nsv914005	chr21:46670874-46756700	Weak transcription Strong transcription Flanking Active TSS Enhancers Transcr. at gene 5' and 3' Genic enhancers Bivalent Enhancer Active TSS ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	40 gene(s)	inside rSNPs	diseases
24	nsv914006	chr21:46670874-46788299	ZNF genes & repeats Weak transcription Strong transcription Enhancers Flanking Active TSS Bivalent Enhancer Genic enhancers Active TSS Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	42 gene(s)	inside rSNPs	diseases
25	esv2762114	chr21:46680202-47067744	Enhancers Weak transcription Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Active TSS Strong transcription Transcr. at gene 5' and 3' Bivalent Enhancer Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	68 gene(s)	inside rSNPs	diseases
26	nsv914007	chr21:46684517-46780249	Weak transcription Enhancers Bivalent Enhancer ZNF genes & repeats Strong transcription Transcr. at gene 5' and 3' Flanking Active TSS Genic enhancers Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	41 gene(s)	inside rSNPs	diseases
27	nsv914008	chr21:46684517-46792424	Flanking Active TSS Enhancers Strong transcription Weak transcription Genic enhancers Flanking Bivalent TSS/Enh Active TSS ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	43 gene(s)	inside rSNPs	diseases
28	nsv914009	chr21:46684517-46908355	Enhancers Strong transcription Genic enhancers Bivalent Enhancer Weak transcription Flanking Active TSS Transcr. at gene 5' and 3' Active TSS ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA	55 gene(s)	inside rSNPs	diseases
29	nsv1057661	chr21:46687476-46961041	Enhancers Flanking Active TSS Bivalent Enhancer Weak transcription Active TSS Genic enhancers Flanking Bivalent TSS/Enh Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	56 gene(s)	inside rSNPs	diseases
30	nsv914010	chr21:46695039-46775018	Weak transcription Flanking Active TSS Enhancers Transcr. at gene 5' and 3' Active TSS Bivalent Enhancer Genic enhancers Strong transcription ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	41 gene(s)	inside rSNPs	diseases
31	nsv914011	chr21:46695039-46788299	Weak transcription Flanking Active TSS Genic enhancers Enhancers ZNF genes & repeats Bivalent Enhancer Strong transcription Transcr. at gene 5' and 3' Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	41 gene(s)	inside rSNPs	diseases
32	nsv914012	chr21:46695039-47015661	Weak transcription Flanking Active TSS Enhancers Strong transcription Active TSS ZNF genes & repeats Bivalent Enhancer Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	66 gene(s)	inside rSNPs	diseases
33	nsv531547	chr21:46698078-46850908	Weak transcription Enhancers Genic enhancers Flanking Active TSS Bivalent Enhancer Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS Strong transcription ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	51 gene(s)	inside rSNPs	diseases
34	nsv914013	chr21:46702506-46765251	Enhancers Flanking Active TSS Weak transcription Active TSS Strong transcription Genic enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
35	nsv914014	chr21:46702506-46780249	Weak transcription Enhancers Strong transcription Flanking Active TSS Active TSS Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	40 gene(s)	inside rSNPs	diseases
36	nsv914015	chr21:46702506-46790203	Weak transcription Enhancers Active TSS Flanking Active TSS Genic enhancers Bivalent Enhancer Strong transcription Flanking Bivalent TSS/Enh ZNF genes & repeats Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	40 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:123 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr21:46708200-46712200	Weak transcription	Primary T helper naive cells from peripheral blood	blood
2	chr21:46708200-46712600	Weak transcription	Primary T killer memory cells from peripheral blood	blood
3	chr21:46708400-46714800	Weak transcription	Fetal Kidney	kidney
4	chr21:46708600-46712200	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
5	chr21:46708600-46712600	Weak transcription	Primary T cells from cord blood	blood
6	chr21:46708600-46713600	Weak transcription	Aorta	Aorta
7	chr21:46708800-46712000	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
8	chr21:46708800-46712000	Weak transcription	Primary monocytes fromperipheralblood	blood
9	chr21:46708800-46712000	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
10	chr21:46708800-46712000	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
11	chr21:46708800-46712000	Weak transcription	Liver	Liver
12	chr21:46708800-46712000	Weak transcription	Colonic Mucosa	Colon
13	chr21:46708800-46712000	Weak transcription	Gastric	stomach
14	chr21:46708800-46712000	Weak transcription	Ovary	ovary
15	chr21:46708800-46712000	Weak transcription	Placenta Amnion	Placenta Amnion
16	chr21:46708800-46712200	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
17	chr21:46708800-46712200	Weak transcription	Brain Angular Gyrus	brain
18	chr21:46708800-46712200	Weak transcription	Brain Substantia Nigra	brain
19	chr21:46708800-46712200	Weak transcription	Left Ventricle	heart
20	chr21:46708800-46712200	Weak transcription	Right Atrium	heart
21	chr21:46708800-46712200	Weak transcription	Sigmoid Colon	Sigmoid Colon
22	chr21:46708800-46712200	Weak transcription	GM12878-XiMat	blood
23	chr21:46708800-46712400	Weak transcription	Primary neutrophils fromperipheralblood	blood
24	chr21:46708800-46712400	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
25	chr21:46708800-46712400	Weak transcription	Lung	lung
26	chr21:46708800-46712400	Weak transcription	Rectal Mucosa Donor 31	rectum
27	chr21:46708800-46712600	Weak transcription	Esophagus	oesophagus
28	chr21:46708800-46712800	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
29	chr21:46708800-46713000	Weak transcription	Psoas Muscle	Psoas
30	chr21:46708800-46713200	Weak transcription	Hela-S3	cervix
31	chr21:46708800-46715000	Weak transcription	H9 Cell Line	embryonic stem cell
32	chr21:46709000-46712000	Weak transcription	H1 Cell Line	embryonic stem cell
33	chr21:46709000-46712000	Weak transcription	Duodenum Mucosa	Duodenum
34	chr21:46709000-46712000	Weak transcription	Fetal Lung	lung
35	chr21:46709000-46712000	Weak transcription	Rectal Smooth Muscle	rectum
36	chr21:46709000-46712000	Weak transcription	Skeletal Muscle Male	skeletal muscle
37	chr21:46709000-46712000	Weak transcription	Monocytes-CD14+_RO01746	blood
38	chr21:46709000-46712200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
39	chr21:46709000-46712200	Weak transcription	HUES48 Cell Line	embryonic stem cell
40	chr21:46709000-46712200	Weak transcription	HUES6 Cell Line	embryonic stem cell
41	chr21:46709000-46712200	Weak transcription	Primary B cells from cord blood	blood
42	chr21:46709000-46712200	Weak transcription	Primary B cells from peripheral blood	blood
43	chr21:46709000-46712200	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
44	chr21:46709000-46712200	Weak transcription	Brain Cingulate Gyrus	brain
45	chr21:46709000-46712200	Weak transcription	Rectal Mucosa Donor 29	rectum
46	chr21:46709000-46712200	Weak transcription	Right Ventricle	heart
47	chr21:46709000-46712400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
48	chr21:46709000-46712600	Weak transcription	iPS-18 Cell Line	embryonic stem cell
49	chr21:46709000-46712600	Weak transcription	Fetal Brain Male	brain
50	chr21:46709000-46713400	Weak transcription	HUES64 Cell Line	embryonic stem cell

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