Variant report

Variant	rs58358810
Chromosome Location	chr14:105558176-105558177
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	MAX	chr14:105556409-105559034	MCF-7	breast:	n/a	chr14:105558119-105558129 chr14:105558711-105558721 chr14:105558880-105558895 chr14:105558887-105558897
2	BCL3	chr14:105557664-105559598	A549	lung:	n/a	chr14:105558706-105558719 chr14:105559120-105559133
3	TCF12	chr14:105556669-105559848	ECC-1	luminal epithelium:	n/a	chr14:105558705-105558715 chr14:105556711-105556721 chr14:105558506-105558516 chr14:105558328-105558335 chr14:105556879-105556889 chr14:105556900-105556910 chr14:105558295-105558305 chr14:105557507-105557514
4	MYC	chr14:105556712-105559367	A549	lung:	n/a	chr14:105558119-105558129 chr14:105558711-105558721 chr14:105558880-105558895 chr14:105559297-105559307 chr14:105558887-105558897
5	STAT3	chr14:105557912-105558276	MCF10A-Er-Src	breast:	n/a	chr14:105558027-105558039 chr14:105558032-105558044
6	USF1	chr14:105557767-105558687	ECC-1	luminal epithelium:	n/a	chr14:105558561-105558577
7	GATA3	chr14:105557859-105558260	T-47D	breast:	n/a	chr14:105558243-105558250
8	GTF2F1	chr14:105557851-105558347	Hela-S3	cervix:	n/a	n/a
9	ESR1	chr14:105557737-105558500	ECC-1	luminal epithelium:	n/a	n/a
10	POLR2A	chr14:105558110-105558380	ProgFib	skin:	n/a	n/a
11	POLR2A	chr14:105557226-105561146	A549	lung:	n/a	n/a
12	BCL3	chr14:105556352-105559650	A549	lung:	n/a	chr14:105559601-105559614 chr14:105558706-105558719 chr14:105559120-105559133
13	FOXM1	chr14:105556756-105558866	ECC-1	luminal epithelium:	n/a	n/a
14	FOXM1	chr14:105557620-105558401	MCF-7	breast:	n/a	n/a
15	SMC3	chr14:105557808-105558305	Hela-S3	cervix:	n/a	chr14:105558088-105558098 chr14:105558217-105558227 chr14:105557823-105557830
16	BRCA1	chr14:105557840-105558255	Hela-S3	cervix:	n/a	n/a
17	RAD21	chr14:105557668-105558707	ECC-1	luminal epithelium:	n/a	chr14:105558217-105558227 chr14:105558452-105558464 chr14:105558088-105558098 chr14:105558320-105558333
18	MYC	chr14:105557906-105558354	MCF10A-Er-Src	breast:	n/a	chr14:105558119-105558129
19	MXI1	chr14:105557834-105558452	Hela-S3	cervix:	n/a	n/a
20	RCOR1	chr14:105557749-105558363	Hela-S3	cervix:	n/a	n/a
21	NR3C1	chr14:105557775-105558289	A549	lung:	n/a	n/a
22	MAX	chr14:105558101-105558270	HepG2	liver:	n/a	chr14:105558119-105558129
23	MAX	chr14:105556809-105559855	ECC-1	luminal epithelium:	n/a	chr14:105558119-105558129 chr14:105558711-105558721 chr14:105558880-105558895 chr14:105559297-105559307 chr14:105559437-105559447 chr14:105558887-105558897
24	EP300	chr14:105557837-105558246	T-47D	breast:	n/a	n/a
25	TCF12	chr14:105552661-105561002	A549	lung:	n/a	chr14:105555506-105555515 chr14:105554733-105554741 chr14:105554099-105554109 chr14:105560562-105560572 chr14:105558705-105558715 chr14:105556711-105556721 chr14:105560974-105560982 chr14:105558506-105558516 chr14:105555994-105556004 chr14:105558328-105558335 chr14:105556609-105556616 chr14:105556879-105556889 chr14:105556900-105556910 chr14:105558295-105558305 chr14:105557507-105557514
26	RFX5	chr14:105557836-105558420	Hela-S3	cervix:	n/a	n/a
27	EP300	chr14:105557476-105558527	MCF-7	breast:	n/a	chr14:105557498-105557514 chr14:105558269-105558285
28	EBF1	chr14:105558113-105558494	GM12878	blood:	n/a	n/a
29	NR3C1	chr14:105557662-105559108	A549	lung:	n/a	chr14:105557679-105557692
30	TEAD4	chr14:105557715-105558718	A549	lung:	n/a	n/a
31	SIN3AK20	chr14:105557504-105558485	MCF-7	breast:	n/a	n/a
32	TEAD4	chr14:105557686-105558483	HCT-116	colon:	n/a	n/a
33	MAX	chr14:105557805-105558645	Hela-S3	cervix:	n/a	chr14:105558119-105558129
34	TEAD4	chr14:105557762-105558393	MCF-7	breast:	n/a	n/a
35	ESR1	chr14:105557759-105558451	ECC-1	luminal epithelium:	n/a	n/a
36	ZBTB33	chr14:105557829-105558255	HCT-116	colon:	n/a	n/a
37	JUND	chr14:105557771-105558409	A549	lung:	n/a	n/a
38	SIX5	chr14:105557722-105558216	A549	lung:	n/a	n/a
39	GATA3	chr14:105557530-105558593	MCF-7	breast:	n/a	chr14:105558243-105558250
40	E2F6	chr14:105557679-105559822	A549	lung:	n/a	chr14:105559639-105559648 chr14:105559574-105559583 chr14:105559645-105559654 chr14:105559790-105559797 chr14:105559118-105559128
41	SRF	chr14:105557669-105558704	ECC-1	luminal epithelium:	n/a	n/a
42	TEAD4	chr14:105556774-105558874	ECC-1	luminal epithelium:	n/a	n/a
43	POLR2A	chr14:105557763-105560968	A549	lung:	n/a	n/a
44	TEAD4	chr14:105557779-105558356	MCF-7	breast:	n/a	n/a
45	STAT3	chr14:105557944-105558304	MCF10A-Er-Src	breast:	n/a	chr14:105558027-105558039 chr14:105558032-105558044
46	FOXA1	chr14:105557970-105558238	T-47D	breast:	n/a	n/a
47	POLR2A	chr14:105557708-105560589	HCT-116	colon:	n/a	n/a
48	FOXA2	chr14:105557776-105558388	A549	lung:	n/a	n/a
49	POLR2A	chr14:105558033-105558482	MCF10A-Er-Src	breast:	n/a	n/a
50	NR3C1	chr14:105557718-105558872	A549	lung:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr14:105541940..105543448-chr14:105558104..105559608,2	K562	blood:
2	chr14:105478025..105480499-chr14:105557134..105559367,2	MCF-7	breast:
3	chr14:105557263..105559202-chr14:105649515..105651192,2	MCF-7	breast:
4	chr14:105556660..105559437-chr14:105588253..105590015,2	MCF-7	breast:
5	chr14:105555328..105560254-chr14:105631379..105635555,5	MCF-7	breast:
6	chr14:105556861..105558363-chr14:105628903..105631842,2	K562	blood:
7	chr14:105433754..105435630-chr14:105557991..105559597,2	MCF-7	breast:
8	chr14:105556047..105558699-chr14:105620485..105622825,2	K562	blood:
9	chr14:105556860..105558487-chr14:105603973..105605818,2	K562	blood:
10	chr12:76420081..76420943-chr14:105558157..105558711,2	HCT-116	colon:
11	chr14:105444294..105445839-chr14:105557247..105559531,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000257556	TF binding region
ENSG00000184916	Chromatin interaction
ENSG00000185567	Chromatin interaction

Extended variants
information (count: 32 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:13)

rs_ID	r²[population]
rs10130160	0.94[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs10132667	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs10149404	0.96[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs28407946	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs28535454	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs28634831	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs59176538	0.87[AMR][1000 genomes]
rs59819555	0.87[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs60165074	0.83[AFR][1000 genomes];0.85[AMR][1000 genomes];1.00[EUR][1000 genomes]
rs61043267	0.87[AMR][1000 genomes]
rs61556877	0.87[AMR][1000 genomes]
rs74092711	1.00[EUR][1000 genomes]
rs74092712	1.00[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:19 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv1828345	chr14:105100787-105803170	Weak transcription Enhancers Strong transcription Genic enhancers Flanking Active TSS Bivalent Enhancer Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	165 gene(s)	inside rSNPs	diseases
2	nsv542225	chr14:105133688-105803170	Enhancers Bivalent/Poised TSS Flanking Active TSS Bivalent Enhancer Weak transcription Active TSS Strong transcription Flanking Bivalent TSS/Enh ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	165 gene(s)	inside rSNPs	diseases
3	nsv542227	chr14:105157572-105803170	Enhancers Flanking Active TSS Genic enhancers Weak transcription Active TSS Strong transcription Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	147 gene(s)	inside rSNPs	diseases
4	nsv917106	chr14:105339195-105803170	Enhancers Flanking Active TSS Weak transcription Active TSS Bivalent Enhancer Bivalent/Poised TSS Strong transcription Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	94 gene(s)	inside rSNPs	diseases
5	nsv902421	chr14:105410183-105574843	Weak transcription Enhancers Genic enhancers Active TSS Flanking Active TSS Strong transcription Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	73 gene(s)	inside rSNPs	diseases
6	nsv902422	chr14:105420215-105803170	Enhancers Flanking Bivalent TSS/Enh Flanking Active TSS Weak transcription Active TSS Genic enhancers ZNF genes & repeats Strong transcription Bivalent Enhancer Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	88 gene(s)	inside rSNPs	diseases
7	nsv1052190	chr14:105423761-105722653	Weak transcription Enhancers Strong transcription Flanking Active TSS ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Genic enhancers Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	81 gene(s)	inside rSNPs	diseases
8	nsv902423	chr14:105430890-105803170	Enhancers Bivalent Enhancer Flanking Active TSS Weak transcription Strong transcription Genic enhancers Active TSS ZNF genes & repeats Bivalent/Poised TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	88 gene(s)	inside rSNPs	diseases
9	nsv1042303	chr14:105435649-105633544	Bivalent Enhancer Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Weak transcription Active TSS ZNF genes & repeats Strong transcription Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	73 gene(s)	inside rSNPs	diseases
10	nsv456458	chr14:105435649-105690092	Flanking Active TSS Weak transcription Enhancers Bivalent Enhancer Strong transcription Active TSS Bivalent/Poised TSS Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	77 gene(s)	inside rSNPs	diseases
11	nsv566150	chr14:105435649-105690092	Weak transcription Enhancers Bivalent Enhancer Flanking Active TSS Bivalent/Poised TSS ZNF genes & repeats Active TSS Genic enhancers Flanking Bivalent TSS/Enh Strong transcription Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	77 gene(s)	inside rSNPs	diseases
12	nsv902424	chr14:105436222-105803170	Genic enhancers Weak transcription Enhancers Bivalent Enhancer Strong transcription Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	86 gene(s)	inside rSNPs	diseases
13	nsv456459	chr14:105459140-105617891	Weak transcription Flanking Active TSS Enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Genic enhancers Active TSS Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
14	nsv566152	chr14:105459140-105617891	Weak transcription Bivalent Enhancer Genic enhancers Strong transcription Enhancers Active TSS ZNF genes & repeats Flanking Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
15	nsv902425	chr14:105463936-105690092	Active TSS Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Enhancers Weak transcription ZNF genes & repeats Bivalent/Poised TSS Genic enhancers Strong transcription Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	60 gene(s)	inside rSNPs	diseases
16	nsv9175	chr14:105496509-105688941	Enhancers Strong transcription Bivalent/Poised TSS Active TSS Weak transcription Bivalent Enhancer ZNF genes & repeats Genic enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	35 gene(s)	inside rSNPs	diseases
17	nsv902427	chr14:105508577-105585347	Enhancers Flanking Active TSS Bivalent/Poised TSS Active TSS Weak transcription Bivalent Enhancer Flanking Bivalent TSS/Enh ZNF genes & repeats Strong transcription Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	25 gene(s)	inside rSNPs	diseases
18	esv2758369	chr14:105513346-105803170	Transcr. at gene 5' and 3' Bivalent Enhancer Flanking Active TSS Enhancers Weak transcription Active TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Genic enhancers Strong transcription Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	42 gene(s)	inside rSNPs	diseases
19	esv2760014	chr14:105513346-105803170	Weak transcription Flanking Bivalent TSS/Enh Bivalent Enhancer Enhancers Flanking Active TSS Active TSS Bivalent/Poised TSS Genic enhancers Strong transcription Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	42 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:97 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:105551600-105559000	Enhancers	Placenta	Placenta
2	chr14:105554000-105559000	Enhancers	Gastric	stomach
3	chr14:105554200-105559000	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
4	chr14:105554200-105559000	Enhancers	Pancreas	Pancrea
5	chr14:105554600-105558400	Enhancers	Breast Myoepithelial Primary Cells	Breast
6	chr14:105554600-105558600	Enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
7	chr14:105554600-105558800	Weak transcription	K562	blood
8	chr14:105554600-105559200	Bivalent Enhancer	Fetal Muscle Trunk	muscle
9	chr14:105554800-105559200	Weak transcription	Primary hematopoietic stem cells	blood
10	chr14:105555400-105559200	Weak transcription	Ovary	ovary
11	chr14:105555600-105558400	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
12	chr14:105555600-105559000	Enhancers	Fetal Muscle Leg	muscle
13	chr14:105555800-105558600	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
14	chr14:105555800-105559000	Weak transcription	H9 Cell Line	embryonic stem cell
15	chr14:105556000-105559000	Enhancers	Placenta Amnion	Placenta Amnion
16	chr14:105556400-105558200	Enhancers	Muscle Satellite Cultured Cells	--
17	chr14:105556400-105558400	Enhancers	Fetal Intestine Large	intestine
18	chr14:105556400-105559200	Enhancers	Sigmoid Colon	Sigmoid Colon
19	chr14:105556400-105559600	Flanking Active TSS	Foreskin Fibroblast Primary Cells skin01	Skin
20	chr14:105556400-105559800	Enhancers	Spleen	Spleen
21	chr14:105556600-105558200	Bivalent Enhancer	Skeletal Muscle Male	skeletal muscle
22	chr14:105556600-105558600	Enhancers	ES-I3 Cell Line	embryonic stem cell
23	chr14:105556600-105559000	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
24	chr14:105556600-105559000	Enhancers	Adipose Nuclei	Adipose
25	chr14:105556600-105559000	Enhancers	Esophagus	oesophagus
26	chr14:105556600-105559000	Enhancers	Fetal Lung	lung
27	chr14:105556600-105559000	Enhancers	Left Ventricle	heart
28	chr14:105556600-105559000	Enhancers	Skeletal Muscle Female	skeletal muscle
29	chr14:105556600-105559200	Enhancers	Right Ventricle	heart
30	chr14:105556600-105559800	Enhancers	Fetal Heart	heart
31	chr14:105556800-105558400	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
32	chr14:105556800-105558400	Enhancers	Duodenum Smooth Muscle	Duodenum
33	chr14:105556800-105558400	Enhancers	Rectal Smooth Muscle	rectum
34	chr14:105556800-105558400	Enhancers	Osteobl	bone
35	chr14:105556800-105558600	Enhancers	Stomach Mucosa	stomach
36	chr14:105556800-105558800	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
37	chr14:105556800-105558800	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
38	chr14:105556800-105559000	Weak transcription	Primary B cells from cord blood	blood
39	chr14:105556800-105559000	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
40	chr14:105556800-105559200	Enhancers	HUES6 Cell Line	embryonic stem cell
41	chr14:105556800-105559200	Enhancers	Primary T helper naive cells fromperipheralblood	blood
42	chr14:105556800-105559200	Enhancers	HSMM	muscle
43	chr14:105556800-105560000	Enhancers	Liver	Liver
44	chr14:105557000-105558600	Enhancers	Lung	lung
45	chr14:105557000-105558800	Enhancers	Fetal Thymus	thymus
46	chr14:105557000-105559400	Enhancers	Brain Anterior Caudate	brain
47	chr14:105557000-105559600	Flanking Active TSS	Stomach Smooth Muscle	stomach
48	chr14:105557200-105558800	Weak transcription	Primary T helper cells PMA-I stimulated	--
49	chr14:105557200-105558800	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
50	chr14:105557200-105559000	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links