Variant report

Variant	rs59686861
Chromosome Location	chr15:73074122-73074123
allele	A/C
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:9)
CpG islands
(count:0)
Chromatin interactive
region (count:5)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:9 , 50 per page) page: 1

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr15:73072441-73074185	GM12878	blood:	n/a	n/a
2	POLR2A	chr15:73073828-73077169	K562	blood:	n/a	n/a
3	POLR2A	chr15:73073416-73074788	GM12878	blood:	n/a	n/a
4	POLR2A	chr15:73073353-73074475	A549	lung:	n/a	n/a
5	POLR2A	chr15:73073835-73074372	MCF10A-Er-Src	breast:	n/a	n/a
6	POLR2A	chr15:73073506-73074212	HepG2	liver:	n/a	n/a
7	WRNIP1	chr15:73073323-73074740	GM12878	blood:	n/a	n/a
8	JUN	chr15:73073554-73077337	K562	blood:	n/a	n/a
9	TBL1XR1	chr15:73073979-73074155	K562	blood:	n/a	n/a

No data

(count:5 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr15:73023517..73026830-chr15:73073635..73076108,3	MCF-7	breast:
2	chr15:73049186..73051770-chr15:73072949..73076067,3	K562	blood:
3	chr15:72976932..72978751-chr15:73073825..73076141,2	MCF-7	breast:
4	chr15:73073926..73075951-chr2:64751420..64752931,2	MCF-7	breast:
5	chr15:73072574..73074689-chr15:73091514..73094026,2	K562	blood:

No data

Variant related genes	Relation type
ADPGK-AS1	TF binding region
ENSG00000175202	Chromatin interaction
ENSG00000119844	Chromatin interaction
ENSG00000159322	Chromatin interaction
ENSG00000140463	Chromatin interaction

Extended variants
information (count: 15 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:11)

rs_ID	r²[population]
rs10467946	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11858132	1.00[ASN][1000 genomes]
rs13379630	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs2277597	0.86[AFR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs35731345	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs3816151	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs57287802	1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs57551071	0.93[ASN][1000 genomes]
rs57769940	1.00[EUR][1000 genomes]
rs58429461	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs60154507	1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:4 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv2758386	chr15:72819785-73120560	Strong transcription ZNF genes & repeats Weak transcription Enhancers Active TSS Flanking Active TSS Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
2	esv2760039	chr15:72819785-73120560	Weak transcription Strong transcription Enhancers Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Transcr. at gene 5' and 3' Genic enhancers Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
3	nsv428307	chr15:72819785-73120560	Strong transcription Flanking Active TSS Active TSS Weak transcription ZNF genes & repeats Enhancers Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	55 gene(s)	inside rSNPs	diseases
4	nsv482512	chr15:73023099-73175952	Flanking Active TSS Strong transcription Weak transcription Enhancers ZNF genes & repeats Active TSS Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	25 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:127 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:73045000-73074200	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
2	chr15:73045200-73074200	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
3	chr15:73048600-73075200	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
4	chr15:73060000-73075000	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
5	chr15:73060200-73075200	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
6	chr15:73061400-73075000	Weak transcription	Fetal Kidney	kidney
7	chr15:73065000-73074200	Weak transcription	Rectal Smooth Muscle	rectum
8	chr15:73065400-73074200	Weak transcription	Brain Germinal Matrix	brain
9	chr15:73066800-73074200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
10	chr15:73067000-73074200	Weak transcription	Rectal Mucosa Donor 31	rectum
11	chr15:73067000-73075000	Weak transcription	Esophagus	oesophagus
12	chr15:73067400-73074200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
13	chr15:73067400-73074200	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
14	chr15:73067400-73074200	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
15	chr15:73067400-73074200	Weak transcription	Fetal Brain Male	brain
16	chr15:73067400-73074200	Weak transcription	Left Ventricle	heart
17	chr15:73067400-73074200	Weak transcription	Lung	lung
18	chr15:73067400-73074200	Weak transcription	Psoas Muscle	Psoas
19	chr15:73067400-73074200	Weak transcription	Right Ventricle	heart
20	chr15:73067400-73074400	Weak transcription	NH-A	brain
21	chr15:73067400-73074600	Weak transcription	Placenta	Placenta
22	chr15:73067400-73074800	Weak transcription	Fetal Brain Female	brain
23	chr15:73067400-73074800	Weak transcription	HUVEC	blood vessel
24	chr15:73067400-73075000	Weak transcription	ES-I3 Cell Line	embryonic stem cell
25	chr15:73067400-73075000	Weak transcription	Aorta	Aorta
26	chr15:73067400-73075000	Weak transcription	Ovary	ovary
27	chr15:73067600-73074200	Weak transcription	Fetal Stomach	stomach
28	chr15:73067600-73074400	Weak transcription	HSMMtube	muscle
29	chr15:73067600-73074600	Weak transcription	Fetal Muscle Trunk	muscle
30	chr15:73067800-73074400	Weak transcription	Colonic Mucosa	Colon
31	chr15:73069000-73075000	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
32	chr15:73071800-73074200	Strong transcription	Fetal Muscle Leg	muscle
33	chr15:73072000-73074200	Genic enhancers	Primary T helper 17 cells PMA-I stimulated	--
34	chr15:73072000-73074400	Strong transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
35	chr15:73072000-73075000	Enhancers	Primary T helper memory cells from peripheral blood 2	blood
36	chr15:73072400-73074800	Weak transcription	HSMM	muscle
37	chr15:73072400-73075000	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
38	chr15:73072600-73074200	Genic enhancers	Primary monocytes fromperipheralblood	blood
39	chr15:73072600-73074200	Genic enhancers	Primary T cells fromperipheralblood	blood
40	chr15:73072800-73074200	Enhancers	Pancreas	Pancrea
41	chr15:73073000-73074200	Genic enhancers	Primary B cells from cord blood	blood
42	chr15:73073000-73074200	Transcr. at gene 5' and 3'	GM12878-XiMat	blood
43	chr15:73073000-73074200	Enhancers	HepG2	liver
44	chr15:73073000-73074600	Transcr. at gene 5' and 3'	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
45	chr15:73073000-73074800	Genic enhancers	Primary B cells from peripheral blood	blood
46	chr15:73073000-73074800	Enhancers	Primary T helper naive cells from peripheral blood	blood
47	chr15:73073200-73074200	Weak transcription	Fetal Intestine Small	intestine
48	chr15:73073200-73074400	Enhancers	Primary neutrophils fromperipheralblood	blood
49	chr15:73073200-73074400	Enhancers	Colon Smooth Muscle	Colon
50	chr15:73073200-73074400	Enhancers	Gastric	stomach

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