Variant report

Variant	rs73259074
Chromosome Location	chr6:167086409-167086410
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

Extended variants
information (count: 22 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:14)

rs_ID	r²[population]
rs1040446	0.90[EUR][1000 genomes]
rs11752332	0.84[AMR][1000 genomes]
rs11966647	0.83[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs2281144	0.82[EUR][1000 genomes]
rs4518470	0.90[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs60078955	0.93[EUR][1000 genomes]
rs62438677	0.82[EUR][1000 genomes]
rs6456100	0.88[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs66472369	0.84[AMR][1000 genomes]
rs6935306	0.88[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs718085	0.82[AMR][1000 genomes]
rs73259086	0.85[EUR][1000 genomes]
rs73259091	0.84[AMR][1000 genomes];0.85[ASN][1000 genomes]
rs7764368	0.81[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:8 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv3490076	chr6:166727901-167306743	Strong transcription Weak transcription Flanking Active TSS Genic enhancers Enhancers Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	25 gene(s)	inside rSNPs	diseases
2	esv3490077	chr6:166727901-167306743	Weak transcription Transcr. at gene 5' and 3' Bivalent Enhancer Enhancers ZNF genes & repeats Active TSS Flanking Active TSS Genic enhancers Strong transcription Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA	25 gene(s)	inside rSNPs	diseases
3	nsv605260	chr6:166984094-167455139	Enhancers Strong transcription Weak transcription Active TSS Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Active TSS Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	13 gene(s)	inside rSNPs	diseases
4	nsv432984	chr6:167018915-167181613	Bivalent Enhancer Enhancers Weak transcription Active TSS Genic enhancers Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	3 gene(s)	inside rSNPs	diseases
5	nsv1020888	chr6:167059455-167136562	Weak transcription Active TSS Enhancers Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3' Strong transcription Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA	2 gene(s)	inside rSNPs	diseases
6	nsv538540	chr6:167059455-167136562	Enhancers ZNF genes & repeats Active TSS Bivalent Enhancer Bivalent/Poised TSS Weak transcription Flanking Bivalent TSS/Enh Flanking Active TSS Transcr. at gene 5' and 3' Genic enhancers Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	2 gene(s)	inside rSNPs	diseases
7	esv2754464	chr6:167059528-167130749	Flanking Bivalent TSS/Enh Weak transcription Enhancers Flanking Active TSS Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Genic enhancers Strong transcription Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	2 gene(s)	inside rSNPs	diseases
8	nsv482478	chr6:167071366-167265821	Weak transcription Bivalent Enhancer Enhancers Flanking Bivalent TSS/Enh Active TSS ZNF genes & repeats Flanking Active TSS Bivalent/Poised TSS Strong transcription Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs73259074	RPS6KA2	cis	Whole Blood	GTEx

Chromatin state (count:44 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr6:167084800-167087200	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
2	chr6:167085000-167086600	Enhancers	HUES48 Cell Line	embryonic stem cell
3	chr6:167085000-167086800	Enhancers	H1 Cell Line	embryonic stem cell
4	chr6:167085000-167087200	Enhancers	Brain Inferior Temporal Lobe	brain
5	chr6:167085000-167088000	Enhancers	Brain Dorsolateral Prefrontal Cortex	brain
6	chr6:167085000-167088200	Bivalent Enhancer	Fetal Stomach	stomach
7	chr6:167085000-167089000	Enhancers	Spleen	Spleen
8	chr6:167085200-167086600	Enhancers	HUES64 Cell Line	embryonic stem cell
9	chr6:167085200-167086800	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
10	chr6:167085200-167086800	Enhancers	HUES6 Cell Line	embryonic stem cell
11	chr6:167085200-167086800	Bivalent Enhancer	Primary hematopoietic stem cells G-CSF-mobilized Male	--
12	chr6:167085200-167087000	Bivalent Enhancer	Primary hematopoietic stem cells short term culture	blood
13	chr6:167085200-167087000	Bivalent Enhancer	Primary hematopoietic stem cells G-CSF-mobilized Female	--
14	chr6:167085200-167087000	Bivalent Enhancer	Fetal Muscle Leg	muscle
15	chr6:167085200-167087000	Enhancers	Left Ventricle	heart
16	chr6:167085200-167087800	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
17	chr6:167085200-167087800	Weak transcription	Pancreas	Pancrea
18	chr6:167085400-167086600	Weak transcription	Gastric	stomach
19	chr6:167085400-167086800	Bivalent Enhancer	Primary hematopoietic stem cells	blood
20	chr6:167085400-167087800	Bivalent Enhancer	Adipose Nuclei	Adipose
21	chr6:167085400-167088800	Enhancers	Skeletal Muscle Female	skeletal muscle
22	chr6:167085400-167091600	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
23	chr6:167085600-167087000	Enhancers	Primary Natural Killer cells fromperipheralblood	blood
24	chr6:167085600-167087800	Weak transcription	Psoas Muscle	Psoas
25	chr6:167085600-167091400	Weak transcription	Placenta Amnion	Placenta Amnion
26	chr6:167085800-167087000	Bivalent Enhancer	Placenta	Placenta
27	chr6:167085800-167087200	Bivalent Enhancer	Fetal Thymus	thymus
28	chr6:167086000-167086800	Weak transcription	Aorta	Aorta
29	chr6:167086000-167087200	Bivalent Enhancer	Fetal Muscle Trunk	muscle
30	chr6:167086200-167086600	Flanking Active TSS	Skeletal Muscle Male	skeletal muscle
31	chr6:167086200-167086800	Enhancers	Brain Cingulate Gyrus	brain
32	chr6:167086200-167086800	Enhancers	Ovary	ovary
33	chr6:167086200-167087200	Bivalent Enhancer	Fetal Adrenal Gland	Adrenal Gland
34	chr6:167086200-167087400	Enhancers	Duodenum Smooth Muscle	Duodenum
35	chr6:167086200-167087800	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
36	chr6:167086200-167088000	Enhancers	Right Ventricle	heart
37	chr6:167086400-167086600	Bivalent Enhancer	Foreskin Melanocyte Primary Cells skin01	Skin
38	chr6:167086400-167086800	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
39	chr6:167086400-167086800	Enhancers	Esophagus	oesophagus
40	chr6:167086400-167087000	Enhancers	Right Atrium	heart
41	chr6:167086400-167087400	Weak transcription	Brain Anterior Caudate	brain
42	chr6:167086400-167087400	Weak transcription	Brain Hippocampus Middle	brain
43	chr6:167086400-167087800	Enhancers	Stomach Smooth Muscle	stomach
44	chr6:167086400-167088600	Enhancers	Lung	lung

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links