Variant report

Variant	rs74060177
Chromosome Location	chr14:69267169-69267170
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	JUND	chr14:69267033-69268076	Hela-S3	cervix:	n/a	n/a
2	FOS	chr14:69267092-69267407	MCF10A-Er-Src	breast:	n/a	n/a
3	JUN	chr14:69266999-69267565	Hela-S3	cervix:	n/a	n/a
4	FOS	chr14:69267115-69267403	MCF10A-Er-Src	breast:	n/a	n/a
5	CEBPB	chr14:69266933-69267521	HCT-116	colon:	n/a	chr14:69267273-69267284
6	CEBPB	chr14:69267036-69268053	Hela-S3	cervix:	n/a	chr14:69267273-69267284
7	TBP	chr14:69266959-69267960	Hela-S3	cervix:	n/a	n/a
8	RCOR1	chr14:69267057-69267413	Hela-S3	cervix:	n/a	n/a
9	MYC	chr14:69267114-69267304	MCF10A-Er-Src	breast:	n/a	n/a
10	FOS	chr14:69267083-69267408	MCF10A-Er-Src	breast:	n/a	n/a
11	CEBPB	chr14:69267103-69267419	A549	lung:	n/a	chr14:69267273-69267284
12	FOS	chr14:69267148-69267373	MCF10A-Er-Src	breast:	n/a	n/a
13	CEBPB	chr14:69266877-69267520	HCT-116	colon:	n/a	chr14:69267273-69267284
14	GATA1	chr14:69266876-69267662	PBDE	blood:	n/a	n/a
15	STAT3	chr14:69266866-69267258	MCF10A-Er-Src	breast:	n/a	n/a
16	EP300	chr14:69266968-69267994	Hela-S3	cervix:	n/a	n/a
17	CEBPB	chr14:69267095-69267424	IMR90	lung:	n/a	chr14:69267273-69267284

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr14:68657329..68659380-chr14:69264255..69267196,2	MCF-7	breast:

Variant related genes	Relation type
ZFP36L1	TF binding region

Extended variants
information (count: 12 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:9)

rs_ID	r²[population]
rs55958232	1.00[AFR][1000 genomes]
rs56392804	1.00[AFR][1000 genomes]
rs74060163	0.97[AFR][1000 genomes]
rs74060165	0.97[AFR][1000 genomes]
rs74060166	1.00[AFR][1000 genomes]
rs74060175	1.00[AFR][1000 genomes]
rs74060183	1.00[AFR][1000 genomes]
rs74060186	0.97[AFR][1000 genomes]
rs74060197	0.80[AFR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1035267	chr14:69230254-69348126	Strong transcription Flanking Active TSS Weak transcription Enhancers Active TSS Transcr. at gene 5' and 3' Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	81 gene(s)	inside rSNPs	diseases
2	nsv542123	chr14:69230254-69348126	Weak transcription Enhancers Genic enhancers Active TSS Flanking Active TSS ZNF genes & repeats Transcr. at gene 5' and 3' Strong transcription Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	81 gene(s)	inside rSNPs	diseases
3	nsv902070	chr14:69244214-69308182	Flanking Active TSS Enhancers Transcr. at gene 5' and 3' Weak transcription Genic enhancers Active TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Strong transcription Bivalent/Poised TSS Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	78 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:37 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:69263200-69273000	Weak transcription	Ovary	ovary
2	chr14:69263200-69273200	Weak transcription	HSMM	muscle
3	chr14:69263600-69273200	Weak transcription	NH-A	brain
4	chr14:69264000-69267200	Weak transcription	Primary T helper cells fromperipheralblood	blood
5	chr14:69264000-69271600	Weak transcription	Stomach Smooth Muscle	stomach
6	chr14:69264200-69267200	Weak transcription	Sigmoid Colon	Sigmoid Colon
7	chr14:69264200-69273200	Weak transcription	Right Atrium	heart
8	chr14:69264200-69273600	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
9	chr14:69264200-69277800	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
10	chr14:69264400-69267400	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
11	chr14:69264400-69272600	Weak transcription	HSMMtube	muscle
12	chr14:69264400-69281200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
13	chr14:69264600-69267200	Enhancers	iPS-15b Cell Line	embryonic stem cell
14	chr14:69264800-69272200	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
15	chr14:69264800-69273200	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
16	chr14:69265400-69267400	ZNF genes & repeats	GM12878-XiMat	blood
17	chr14:69265600-69267800	Weak transcription	Cortex derived primary cultured neurospheres	brain
18	chr14:69266200-69267400	Enhancers	Primary B cells from peripheral blood	blood
19	chr14:69266600-69267400	Enhancers	HUES48 Cell Line	embryonic stem cell
20	chr14:69266600-69269200	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
21	chr14:69266800-69267200	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
22	chr14:69266800-69267400	Enhancers	Primary T helper cells PMA-I stimulated	--
23	chr14:69266800-69267800	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
24	chr14:69266800-69268000	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
25	chr14:69266800-69268000	Enhancers	Dnd41	blood
26	chr14:69266800-69269200	Enhancers	Hela-S3	cervix
27	chr14:69267000-69267200	Enhancers	H1 Cell Line	embryonic stem cell
28	chr14:69267000-69267200	Enhancers	Primary T killer memory cells from peripheral blood	blood
29	chr14:69267000-69267400	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
30	chr14:69267000-69267400	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Male	--
31	chr14:69267000-69267400	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
32	chr14:69267000-69267400	Enhancers	A549	lung
33	chr14:69267000-69267600	Enhancers	NHEK	skin
34	chr14:69267000-69268000	Enhancers	Muscle Satellite Cultured Cells	--
35	chr14:69267000-69268000	Enhancers	Foreskin Melanocyte Primary Cells skin01	Skin
36	chr14:69267000-69268000	Enhancers	Osteobl	bone
37	chr14:69267000-69268200	Enhancers	HMEC	breast

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