Variant report

Variant	rs74112209
Chromosome Location	chr10:6278021-6278022
allele	G/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:6269695..6272460-chr10:6277246..6279145,2	K562	blood:
2	chr10:6269994..6271689-chr10:6275585..6278194,2	K562	blood:
3	chr10:6275845..6278473-chr10:6279754..6281558,4	MCF-7	breast:
4	chr10:6276012..6279059-chr10:6319124..6321849,3	MCF-7	breast:
5	chr10:6273635..6276470-chr10:6276931..6279264,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000215244	Chromatin interaction

Extended variants
information (count: 18 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:11)

rs_ID	r²[population]
rs17152229	0.82[ASN][1000 genomes]
rs17152396	0.84[AMR][1000 genomes];0.89[ASN][1000 genomes]
rs17152400	0.97[AFR][1000 genomes];0.94[AMR][1000 genomes];0.86[ASN][1000 genomes]
rs35929982	0.86[ASN][1000 genomes]
rs56046905	0.93[AFR][1000 genomes]
rs59400494	0.86[AFR][1000 genomes]
rs7074366	0.86[ASN][1000 genomes]
rs7088179	0.86[ASN][1000 genomes]
rs74112210	0.82[AFR][1000 genomes];0.94[AMR][1000 genomes];1.00[ASN][1000 genomes]
rs74112211	0.82[AFR][1000 genomes];0.94[AMR][1000 genomes];1.00[ASN][1000 genomes]
rs74112213	0.82[AFR][1000 genomes];0.94[AMR][1000 genomes];0.89[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:7 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1042286	chr10:5795129-6578445	Enhancers Weak transcription Genic enhancers Active TSS Flanking Active TSS Strong transcription Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	76 gene(s)	inside rSNPs	diseases
2	nsv1040721	chr10:6155144-6322566	Weak transcription Enhancers Flanking Active TSS Bivalent Enhancer Active TSS Strong transcription Flanking Bivalent TSS/Enh Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	31 gene(s)	inside rSNPs	diseases
3	nsv540476	chr10:6155144-6322566	Genic enhancers Flanking Active TSS Enhancers Weak transcription Flanking Bivalent TSS/Enh Active TSS Strong transcription Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	31 gene(s)	inside rSNPs	diseases
4	nsv1054044	chr10:6155144-6487217	Weak transcription Enhancers Strong transcription Flanking Active TSS Active TSS Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	40 gene(s)	inside rSNPs	diseases
5	nsv1041039	chr10:6217724-6354858	Flanking Active TSS Enhancers Weak transcription Genic enhancers Strong transcription Active TSS Bivalent Enhancer Bivalent/Poised TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	28 gene(s)	inside rSNPs	diseases
6	nsv894836	chr10:6246678-6435374	Flanking Active TSS Strong transcription Weak transcription Enhancers Bivalent Enhancer Genic enhancers ZNF genes & repeats Active TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	19 gene(s)	inside rSNPs	diseases
7	nsv525622	chr10:6251252-6281215	Weak transcription Enhancers Strong transcription Genic enhancers Flanking Active TSS Transcr. at gene 5' and 3' ZNF genes & repeats Active TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	4 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:121 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:6247000-6280600	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
2	chr10:6247200-6281000	Weak transcription	Primary T killer memory cells from peripheral blood	blood
3	chr10:6253200-6278800	Strong transcription	Monocytes-CD14+_RO01746	blood
4	chr10:6253400-6278400	Strong transcription	Primary T helper cells PMA-I stimulated	--
5	chr10:6253800-6281000	Weak transcription	Stomach Mucosa	stomach
6	chr10:6254400-6279200	Strong transcription	Dnd41	blood
7	chr10:6254600-6279200	Strong transcription	Cortex derived primary cultured neurospheres	brain
8	chr10:6254600-6280000	Strong transcription	Primary neutrophils fromperipheralblood	blood
9	chr10:6255000-6279200	Strong transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
10	chr10:6255000-6279200	Strong transcription	Fetal Stomach	stomach
11	chr10:6255200-6279200	Strong transcription	Primary T cells from cord blood	blood
12	chr10:6255200-6279200	Strong transcription	Primary hematopoietic stem cells short term culture	blood
13	chr10:6255200-6279400	Strong transcription	Primary T helper 17 cells PMA-I stimulated	--
14	chr10:6255400-6278400	Strong transcription	Liver	Liver
15	chr10:6255400-6278600	Strong transcription	Primary monocytes fromperipheralblood	blood
16	chr10:6255400-6278800	Strong transcription	HUES64 Cell Line	embryonic stem cell
17	chr10:6255400-6279000	Strong transcription	Fetal Adrenal Gland	Adrenal Gland
18	chr10:6255400-6279400	Strong transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
19	chr10:6255800-6278800	Strong transcription	Fetal Brain Female	brain
20	chr10:6256200-6279000	Strong transcription	H9 Derived Neuron Cultured Cells	ES cell derived
21	chr10:6256200-6279200	Strong transcription	Adipose Nuclei	Adipose
22	chr10:6256400-6279200	Strong transcription	Skeletal Muscle Male	skeletal muscle
23	chr10:6257000-6278800	Strong transcription	Brain Substantia Nigra	brain
24	chr10:6260200-6279400	Strong transcription	Lung	lung
25	chr10:6260600-6279400	Strong transcription	Brain Germinal Matrix	brain
26	chr10:6261000-6279400	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
27	chr10:6261600-6278200	Strong transcription	Placenta	Placenta
28	chr10:6261600-6278800	Strong transcription	Skeletal Muscle Female	skeletal muscle
29	chr10:6261800-6281000	Weak transcription	NHDF-Ad	bronchial
30	chr10:6264800-6279200	Strong transcription	Stomach Smooth Muscle	stomach
31	chr10:6265000-6279000	Strong transcription	IMR90 fetal lung fibroblasts Cell Line	lung
32	chr10:6265200-6278800	Strong transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
33	chr10:6266400-6279400	Strong transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
34	chr10:6270000-6279800	Strong transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
35	chr10:6270400-6279000	Strong transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
36	chr10:6270600-6288600	Weak transcription	Fetal Kidney	kidney
37	chr10:6270800-6279200	Strong transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
38	chr10:6271000-6278600	Strong transcription	Primary T cells fromperipheralblood	blood
39	chr10:6271200-6278400	Strong transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
40	chr10:6271400-6278600	Strong transcription	Primary B cells from peripheral blood	blood
41	chr10:6272600-6281000	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
42	chr10:6272600-6281000	Weak transcription	K562	blood
43	chr10:6272800-6279200	Strong transcription	Primary T helper naive cells fromperipheralblood	blood
44	chr10:6273600-6281000	Weak transcription	Hela-S3	cervix
45	chr10:6273600-6287800	Weak transcription	ES-I3 Cell Line	embryonic stem cell
46	chr10:6274000-6279800	Weak transcription	Fetal Intestine Large	intestine
47	chr10:6274800-6279400	Strong transcription	Rectal Smooth Muscle	rectum
48	chr10:6274800-6280800	Weak transcription	HUVEC	blood vessel
49	chr10:6275400-6278800	Strong transcription	Brain Hippocampus Middle	brain
50	chr10:6275400-6279200	Strong transcription	Brain Anterior Caudate	brain

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links