Variant report

Variant	rs7581184
Chromosome Location	chr2:11489531-11489532
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	MYBL2	chr2:11488228-11489642	HepG2	liver:	n/a	n/a
2	POLR2A	chr2:11488324-11490899	HepG2	liver:	n/a	n/a
3	POLR2A	chr2:11489531-11490196	HepG2	liver:	n/a	n/a
4	POLR2A	chr2:11489032-11489535	HepG2	liver:	n/a	n/a
5	POLR2A	chr2:11488265-11490650	HepG2	liver:	n/a	n/a

Variant related genes	Relation type
ROCK2	TF binding region
ENSG00000226961	TF binding region

Extended variants
information (count: 16 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:13)

rs_ID	r²[population]
rs10167277	0.84[CEU][hapmap]
rs10202323	0.81[JPT][hapmap]
rs10208872	1.00[CEU][hapmap];0.87[CHB][hapmap];0.93[GIH][hapmap];0.93[MEX][hapmap];0.91[TSI][hapmap];0.93[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs10929728	0.85[CEU][hapmap]
rs12692438	0.86[JPT][hapmap]
rs12692440	0.85[JPT][hapmap]
rs12692441	0.81[JPT][hapmap]
rs12993210	0.86[JPT][hapmap]
rs4668722	0.81[JPT][hapmap]
rs6432187	0.87[CHB][hapmap];0.91[GIH][hapmap];0.84[MEX][hapmap]
rs6716724	0.86[JPT][hapmap]
rs6739422	0.87[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs7595700	0.86[JPT][hapmap]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv526038	chr2:11369078-11489531	Weak transcription ZNF genes & repeats Enhancers Flanking Active TSS Strong transcription Active TSS Genic enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	19 gene(s)	inside rSNPs	diseases
2	nsv1010506	chr2:11430965-12057286	Enhancers Strong transcription Weak transcription Bivalent Enhancer Flanking Active TSS Active TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	88 gene(s)	inside rSNPs	diseases
3	nsv535585	chr2:11430965-12057286	Enhancers Flanking Active TSS Bivalent/Poised TSS Weak transcription ZNF genes & repeats Active TSS Strong transcription Transcr. at gene 5' and 3' Bivalent Enhancer Genic enhancers Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	88 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs7581184	ROCK2	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:20 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr2:11485800-11497400	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
2	chr2:11485800-11497400	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
3	chr2:11486200-11493800	Weak transcription	Stomach Mucosa	stomach
4	chr2:11486400-11489800	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
5	chr2:11486400-11490400	Enhancers	HepG2	liver
6	chr2:11486600-11489600	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
7	chr2:11486600-11493000	Weak transcription	Lung	lung
8	chr2:11488400-11490000	Enhancers	Ganglion Eminence derived primary cultured neurospheres	brain
9	chr2:11488400-11490200	Enhancers	Cortex derived primary cultured neurospheres	brain
10	chr2:11488600-11490200	Enhancers	Breast Myoepithelial Primary Cells	Breast
11	chr2:11488800-11494000	Weak transcription	iPS-18 Cell Line	embryonic stem cell
12	chr2:11489000-11492600	Weak transcription	Fetal Intestine Large	intestine
13	chr2:11489000-11492600	Weak transcription	Placenta	Placenta
14	chr2:11489000-11495600	Weak transcription	Skeletal Muscle Female	skeletal muscle
15	chr2:11489200-11492600	Weak transcription	Liver	Liver
16	chr2:11489400-11489800	Weak transcription	Brain Substantia Nigra	brain
17	chr2:11489400-11492800	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
18	chr2:11489400-11493400	Weak transcription	Gastric	stomach
19	chr2:11489400-11494600	Weak transcription	Fetal Intestine Small	intestine
20	chr2:11489400-11496800	Weak transcription	Adipose Nuclei	Adipose

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