Variant report

Variant	rs10008186
Chromosome Location	chr4:8464389-8464390
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr4:8448752..8450520-chr4:8461645..8464586,2	MCF-7	breast:
2	chr4:8455487..8458009-chr4:8461888..8464804,2	MCF-7	breast:
3	chr4:8457452..8459896-chr4:8461830..8464579,3	K562	blood:
4	chr4:8463804..8466196-chr4:8524199..8526548,2	MCF-7	breast:
5	chr4:8461947..8464709-chr4:8593943..8596548,3	MCF-7	breast:

Variant related genes	Relation type
ENSG00000109625	Chromatin interaction
ENSG00000251186	Chromatin interaction
ENSG00000155275	Chromatin interaction

Extended variants
information (count: 20 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:16)

rs_ID	r²[population]
rs10009833	0.85[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs10012186	0.81[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs10015429	0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs10029016	0.86[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs10031818	0.86[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs10938715	0.84[AFR][1000 genomes];0.90[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11736150	0.86[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs11737745	0.89[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs11934642	0.84[AMR][1000 genomes];0.96[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs13105919	0.85[EUR][1000 genomes]
rs28536709	0.85[EUR][1000 genomes]
rs28544429	0.85[EUR][1000 genomes]
rs28739492	0.83[EUR][1000 genomes]
rs2972	0.85[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs3796741	0.85[ASN][1000 genomes]
rs71603931	0.85[EUR][1000 genomes];0.89[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:4 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1002794	chr4:8110083-8490934	Weak transcription Bivalent Enhancer Enhancers Flanking Active TSS Strong transcription Flanking Bivalent TSS/Enh Bivalent/Poised TSS Genic enhancers Active TSS ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	30 gene(s)	inside rSNPs	diseases
2	nsv878604	chr4:8315938-8618916	Enhancers Flanking Active TSS Strong transcription Weak transcription Active TSS Bivalent/Poised TSS Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	19 gene(s)	inside rSNPs	diseases
3	nsv1002680	chr4:8357163-8721214	Active TSS Flanking Active TSS Strong transcription Weak transcription Enhancers Bivalent Enhancer Bivalent/Poised TSS Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	18 gene(s)	inside rSNPs	diseases
4	nsv829854	chr4:8402921-8506407	Strong transcription Bivalent Enhancer Flanking Bivalent TSS/Enh Enhancers Weak transcription Flanking Active TSS ZNF genes & repeats Active TSS Transcr. at gene 5' and 3' Genic enhancers Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:124 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr4:8446400-8473800	Strong transcription	Fetal Stomach	stomach
2	chr4:8446600-8464600	Strong transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
3	chr4:8446600-8473400	Strong transcription	Dnd41	blood
4	chr4:8446600-8474000	Strong transcription	Fetal Muscle Leg	muscle
5	chr4:8447000-8474400	Strong transcription	Fetal Brain Female	brain
6	chr4:8447000-8475200	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
7	chr4:8447000-8480200	Strong transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
8	chr4:8447200-8473000	Strong transcription	Breast Myoepithelial Primary Cells	Breast
9	chr4:8447200-8480200	Strong transcription	Primary mononuclear cells fromperipheralblood	Blood
10	chr4:8447400-8474000	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
11	chr4:8447400-8482200	Strong transcription	Primary T cells from cord blood	blood
12	chr4:8447600-8472200	Strong transcription	Primary Natural Killer cells fromperipheralblood	blood
13	chr4:8447600-8473400	Strong transcription	Monocytes-CD14+_RO01746	blood
14	chr4:8447800-8472800	Strong transcription	Primary T helper cells fromperipheralblood	blood
15	chr4:8448200-8467400	Strong transcription	Adipose Nuclei	Adipose
16	chr4:8451200-8473600	Strong transcription	H9 Derived Neuron Cultured Cells	ES cell derived
17	chr4:8456000-8469800	Weak transcription	Stomach Mucosa	stomach
18	chr4:8456200-8467200	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
19	chr4:8456400-8467000	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
20	chr4:8456800-8468600	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
21	chr4:8457000-8466200	Weak transcription	Pancreatic Islets	Pancreatic Islet
22	chr4:8457200-8464800	Weak transcription	iPS-15b Cell Line	embryonic stem cell
23	chr4:8457200-8470600	Strong transcription	Fetal Muscle Trunk	muscle
24	chr4:8457800-8470800	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
25	chr4:8458200-8465200	Weak transcription	NH-A	brain
26	chr4:8458200-8465200	Weak transcription	Osteobl	bone
27	chr4:8458200-8465800	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
28	chr4:8458200-8472000	Weak transcription	Fetal Heart	heart
29	chr4:8458600-8467000	Weak transcription	Muscle Satellite Cultured Cells	--
30	chr4:8459400-8474000	Strong transcription	Fetal Intestine Small	intestine
31	chr4:8459600-8470000	Weak transcription	Fetal Brain Male	brain
32	chr4:8459800-8466800	Weak transcription	NHLF	lung
33	chr4:8459800-8478800	Weak transcription	Primary T helper naive cells from peripheral blood	blood
34	chr4:8460000-8465400	Weak transcription	Rectal Smooth Muscle	rectum
35	chr4:8460000-8466200	Weak transcription	Primary neutrophils fromperipheralblood	blood
36	chr4:8460000-8466200	Weak transcription	Colonic Mucosa	Colon
37	chr4:8460000-8466600	Weak transcription	Primary T killer memory cells from peripheral blood	blood
38	chr4:8460000-8470000	Weak transcription	K562	blood
39	chr4:8460200-8466000	Weak transcription	iPS-18 Cell Line	embryonic stem cell
40	chr4:8460200-8466800	Weak transcription	HUVEC	blood vessel
41	chr4:8460200-8467000	Weak transcription	HMEC	breast
42	chr4:8460200-8469000	Weak transcription	Small Intestine	intestine
43	chr4:8460200-8470800	Weak transcription	ES-I3 Cell Line	embryonic stem cell
44	chr4:8461000-8466800	Weak transcription	H9 Cell Line	embryonic stem cell
45	chr4:8461200-8465400	Weak transcription	Gastric	stomach
46	chr4:8461400-8464800	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
47	chr4:8461400-8465400	Weak transcription	HUES64 Cell Line	embryonic stem cell
48	chr4:8461400-8466000	Weak transcription	Fetal Thymus	thymus
49	chr4:8461600-8465200	Weak transcription	Aorta	Aorta
50	chr4:8461600-8466800	Weak transcription	H1 Cell Line	embryonic stem cell

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