Variant report

Variant	rs10085346
Chromosome Location	chr6:142619086-142619087
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:62)
CpG islands
(count:0)
Chromatin interactive
region (count:7)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:62 , 50 per page) page: 1 2

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	FOXA1	chr6:142619005-142619754	HepG2	liver:	n/a	n/a
2	JUN	chr6:142619086-142619898	HepG2	liver:	n/a	n/a
3	EP300	chr6:142618931-142619644	A549	lung:	n/a	n/a
4	HDAC2	chr6:142618966-142619723	HepG2	liver:	n/a	n/a
5	POLR2A	chr6:142619008-142619208	MCF10A-Er-Src	breast:	n/a	n/a
6	TCF12	chr6:142618996-142620165	SK-N-SH	brain:	n/a	n/a
7	TCF12	chr6:142618933-142619792	A549	lung:	n/a	n/a
8	SP1	chr6:142619052-142619603	A549	lung:	n/a	n/a
9	TCF7L2	chr6:142617505-142619445	HepG2	liver:	n/a	n/a
10	PBX3	chr6:142619043-142619967	SK-N-SH	brain:	n/a	n/a
11	TEAD4	chr6:142619046-142619563	A549	lung:	n/a	n/a
12	MBD4	chr6:142618054-142619679	HepG2	liver:	n/a	n/a
13	EP300	chr6:142618965-142619733	A549	lung:	n/a	n/a
14	NFIC	chr6:142619007-142619712	HepG2	liver:	n/a	n/a
15	MXI1	chr6:142619021-142619979	IMR90	lung:	n/a	n/a
16	HDAC2	chr6:142618979-142619603	HepG2	liver:	n/a	n/a
17	SP1	chr6:142619001-142619656	A549	lung:	n/a	n/a
18	SP1	chr6:142618987-142619634	HepG2	liver:	n/a	n/a
19	MXI1	chr6:142619028-142619703	HepG2	liver:	n/a	n/a
20	RCOR1	chr6:142619080-142619564	HepG2	liver:	n/a	n/a
21	HNF4A	chr6:142618981-142619509	HepG2	liver:	n/a	n/a
22	FOXA1	chr6:142619034-142619517	A549	lung:	n/a	n/a
23	HNF4G	chr6:142619072-142619521	HepG2	liver:	n/a	n/a
24	PBX3	chr6:142619060-142620115	SK-N-SH	brain:	n/a	n/a
25	NFIC	chr6:142618942-142619705	HepG2	liver:	n/a	n/a
26	FOXA1	chr6:142617792-142620068	HepG2	liver:	n/a	n/a
27	GATA3	chr6:142619060-142620052	SK-N-SH	brain:	n/a	chr6:142619390-142619400
28	CREB1	chr6:142619008-142619684	HepG2	liver:	n/a	n/a
29	FOS	chr6:142619048-142619963	MCF10A-Er-Src	breast:	n/a	n/a
30	GATA3	chr6:142618951-142619937	A549	lung:	n/a	chr6:142619390-142619400
31	MBD4	chr6:142618937-142619710	HepG2	liver:	n/a	n/a
32	MAX	chr6:142619066-142619748	HepG2	liver:	n/a	n/a
33	CEBPB	chr6:142618988-142619633	A549	lung:	n/a	n/a
34	FOXA2	chr6:142618997-142619473	A549	lung:	n/a	n/a
35	POLR2A	chr6:142619053-142619735	PANC-1	pancreas:	n/a	n/a
36	MYBL2	chr6:142617477-142619825	HepG2	liver:	n/a	n/a
37	EP300	chr6:142618990-142619706	HepG2	liver:	n/a	n/a
38	TEAD4	chr6:142617606-142620027	HepG2	liver:	n/a	n/a
39	MAX	chr6:142619022-142619736	A549	lung:	n/a	n/a
40	FOXA2	chr6:142617672-142619842	HepG2	liver:	n/a	n/a
41	FOXA1	chr6:142618900-142619631	HepG2	liver:	n/a	n/a
42	HNF4A	chr6:142618995-142619431	HepG2	liver:	n/a	n/a
43	TEAD4	chr6:142619004-142619551	A549	lung:	n/a	n/a
44	EP300	chr6:142618924-142620139	SK-N-SH	brain:	n/a	n/a
45	FOS	chr6:142619084-142619925	MCF10A-Er-Src	breast:	n/a	n/a
46	JUND	chr6:142619080-142619929	HepG2	liver:	n/a	n/a
47	FOXA1	chr6:142618945-142619691	HepG2	liver:	n/a	n/a
48	CEBPB	chr6:142619063-142619528	HepG2	liver:	n/a	n/a
49	POLR2A	chr6:142619066-142619252	HepG2	liver:	n/a	n/a
50	FOXA1	chr6:142619049-142619392	T-47D	breast:	n/a	n/a

No data

(count:7 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr6:142616393..142621187-chr6:142621251..142624872,10	MCF-7	breast:
2	chr6:142617568..142620556-chr6:142699575..142701431,2	MCF-7	breast:
3	chr6:142604317..142606541-chr6:142618207..142619973,2	MCF-7	breast:
4	chr6:142546061..142548979-chr6:142618829..142620603,2	MCF-7	breast:
5	chr6:142617299..142619130-chr6:142622644..142624388,2	K562	blood:
6	chr6:142614542..142616316-chr6:142618256..142620564,2	K562	blood:
7	chr6:142617630..142619317-chr6:142622644..142625547,2	K562	blood:

No data

Variant related genes	Relation type
GPR126	TF binding region
ENSG00000112414	Chromatin interaction

Extended variants
information (count: 5 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:2)

rs_ID	r²[population]
rs10085197	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs6914490	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv949088	chr6:142561402-143128849	Weak transcription Enhancers Strong transcription Genic enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats Active TSS Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	16 gene(s)	inside rSNPs	diseases
2	nsv830825	chr6:142585242-142752575	Enhancers Weak transcription Active TSS Genic enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS Strong transcription Flanking Bivalent TSS/Enh Flanking Active TSS ZNF genes & repeats Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	10 gene(s)	inside rSNPs	diseases
3	nsv1029666	chr6:142594099-142643084	Enhancers Weak transcription Active TSS Flanking Active TSS Transcr. at gene 5' and 3' Bivalent/Poised TSS Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Strong transcription ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	5 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:38 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr6:142616400-142621800	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
2	chr6:142616600-142619200	Weak transcription	Primary monocytes fromperipheralblood	blood
3	chr6:142617800-142620000	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
4	chr6:142618000-142620400	Flanking Active TSS	HepG2	liver
5	chr6:142618200-142619200	Enhancers	ES-WA7 Cell Line	embryonic stem cell
6	chr6:142618200-142619200	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
7	chr6:142618200-142619200	Enhancers	A549	lung
8	chr6:142618200-142619800	Enhancers	HUES48 Cell Line	embryonic stem cell
9	chr6:142618200-142620000	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
10	chr6:142618200-142621800	Enhancers	HMEC	breast
11	chr6:142618400-142619400	Enhancers	Foreskin Melanocyte Primary Cells skin01	Skin
12	chr6:142618400-142619400	Enhancers	Monocytes-CD14+_RO01746	blood
13	chr6:142618400-142620400	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
14	chr6:142618400-142620400	Enhancers	NHLF	lung
15	chr6:142618400-142620600	Enhancers	H9 Derived Neuron Cultured Cells	ES cell derived
16	chr6:142618400-142621600	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
17	chr6:142618400-142621600	Enhancers	NHEK	skin
18	chr6:142618600-142619400	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
19	chr6:142618600-142619600	Enhancers	H1 Cell Line	embryonic stem cell
20	chr6:142618600-142619600	Enhancers	iPS-20b Cell Line	embryonic stem cell
21	chr6:142618600-142619800	Enhancers	Foreskin Fibroblast Primary Cells skin01	Skin
22	chr6:142618600-142620400	Enhancers	HUVEC	blood vessel
23	chr6:142618600-142620600	Enhancers	HSMM	muscle
24	chr6:142618600-142621800	Weak transcription	Stomach Mucosa	stomach
25	chr6:142618800-142619400	Weak transcription	Placenta	Placenta
26	chr6:142618800-142620000	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
27	chr6:142618800-142621800	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
28	chr6:142618800-142622000	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
29	chr6:142619000-142619200	Enhancers	ES-UCSF4 Cell Line	embryonic stem cell
30	chr6:142619000-142619600	Enhancers	H9 Cell Line	embryonic stem cell
31	chr6:142619000-142619600	Enhancers	HUES64 Cell Line	embryonic stem cell
32	chr6:142619000-142619600	Enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
33	chr6:142619000-142619600	Enhancers	NHDF-Ad	bronchial
34	chr6:142619000-142619800	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
35	chr6:142619000-142619800	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
36	chr6:142619000-142619800	Flanking Active TSS	Muscle Satellite Cultured Cells	--
37	chr6:142619000-142619800	Enhancers	HSMMtube	muscle
38	chr6:142619000-142620000	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow

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