Variant report

Variant	rs11072449
Chromosome Location	chr15:74234484-74234485
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	MYC	chr15:74234457-74234542	MCF-7	breast:	n/a	n/a
2	POLR2A	chr15:74232236-74234567	U87	brain:	n/a	n/a
3	MAZ	chr15:74232601-74235292	IMR90	lung:	n/a	n/a
4	POLR2A	chr15:74234395-74234512	MCF-7	breast:	n/a	n/a
5	MAFK	chr15:74234427-74234820	IMR90	lung:	n/a	chr15:74234722-74234736 chr15:74234724-74234735 chr15:74234723-74234734 chr15:74234455-74234470
6	POLR2A	chr15:74217872-74240199	U87	brain:	n/a	n/a
7	POLR2A	chr15:74215819-74242527	U87	brain:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr15:74214579..74216855-chr15:74233095..74234703,2	K562	blood:
2	chr15:74231331..74232913-chr15:74233031..74235989,2	K562	blood:
3	chr15:74233799..74236609-chr15:74239283..74241933,2	K562	blood:
4	chr15:74234337..74237104-chr15:74240874..74243639,2	MCF-7	breast:

Variant related genes	Relation type
LOXL1	TF binding region
ENSG00000129038	Chromatin interaction

Extended variants
information (count: 7 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:2)

rs_ID	r²[population]
rs10851865	0.97[AFR][1000 genomes]
rs7173840	0.99[AFR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:5 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1043335	chr15:74078689-74241186	Weak transcription Flanking Active TSS Strong transcription Enhancers Bivalent Enhancer Genic enhancers Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	17 gene(s)	inside rSNPs	diseases
2	nsv1603	chr15:74191222-74235733	Enhancers Flanking Active TSS Bivalent/Poised TSS Bivalent Enhancer Active TSS Weak transcription Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Strong transcription Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	15 gene(s)	inside rSNPs	diseases
3	esv2758387	chr15:74215114-74464916	Enhancers Flanking Active TSS Bivalent/Poised TSS Weak transcription Strong transcription Active TSS Flanking Bivalent TSS/Enh Genic enhancers Bivalent Enhancer Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	32 gene(s)	inside rSNPs	diseases
4	esv2760040	chr15:74215114-74464916	Weak transcription Enhancers Strong transcription Flanking Bivalent TSS/Enh Active TSS Flanking Active TSS Bivalent Enhancer Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	32 gene(s)	inside rSNPs	diseases
5	nsv428308	chr15:74215114-74464916	Transcr. at gene 5' and 3' Enhancers Weak transcription Bivalent Enhancer Bivalent/Poised TSS Strong transcription Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	32 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:88 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:74222600-74243200	Weak transcription	Duodenum Smooth Muscle	Duodenum
2	chr15:74227600-74236600	Weak transcription	Thymus	Thymus
3	chr15:74228400-74239600	Weak transcription	Pancreas	Pancrea
4	chr15:74228800-74243200	Weak transcription	Brain Inferior Temporal Lobe	brain
5	chr15:74229000-74236600	Weak transcription	Brain Substantia Nigra	brain
6	chr15:74229000-74243000	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
7	chr15:74229200-74236400	Weak transcription	Breast Myoepithelial Primary Cells	Breast
8	chr15:74229200-74236800	Weak transcription	Esophagus	oesophagus
9	chr15:74229200-74241000	Weak transcription	Pancreatic Islets	Pancreatic Islet
10	chr15:74229600-74237000	Genic enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
11	chr15:74230000-74236400	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
12	chr15:74230000-74236600	Weak transcription	Primary hematopoietic stem cells short term culture	blood
13	chr15:74230000-74239200	Weak transcription	H9 Derived Neuron Cultured Cells	ES cell derived
14	chr15:74230200-74236400	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
15	chr15:74231400-74234600	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
16	chr15:74231400-74234600	Genic enhancers	Fetal Stomach	stomach
17	chr15:74231400-74235000	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
18	chr15:74231400-74235000	Enhancers	Fetal Muscle Trunk	muscle
19	chr15:74231400-74235400	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
20	chr15:74231400-74235400	Enhancers	Placenta Amnion	Placenta Amnion
21	chr15:74231400-74235600	Enhancers	Aorta	Aorta
22	chr15:74231400-74238000	Enhancers	Placenta	Placenta
23	chr15:74231600-74234800	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
24	chr15:74231600-74235200	Enhancers	Right Ventricle	heart
25	chr15:74231600-74235200	Enhancers	Skeletal Muscle Male	skeletal muscle
26	chr15:74231800-74235200	Enhancers	Fetal Heart	heart
27	chr15:74231800-74242800	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
28	chr15:74232200-74234800	Enhancers	Fetal Adrenal Gland	Adrenal Gland
29	chr15:74232200-74235600	Enhancers	Spleen	Spleen
30	chr15:74232400-74236600	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
31	chr15:74232600-74239400	Weak transcription	Brain Anterior Caudate	brain
32	chr15:74232600-74243000	Weak transcription	Brain Hippocampus Middle	brain
33	chr15:74232800-74234800	Enhancers	Fetal Muscle Leg	muscle
34	chr15:74232800-74235200	Enhancers	Skeletal Muscle Female	skeletal muscle
35	chr15:74232800-74235400	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
36	chr15:74232800-74235400	Enhancers	Adipose Nuclei	Adipose
37	chr15:74232800-74244000	Weak transcription	H9 Cell Line	embryonic stem cell
38	chr15:74233000-74234800	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
39	chr15:74233000-74236000	Enhancers	Primary T helper memory cells from peripheral blood 2	blood
40	chr15:74233000-74237200	Weak transcription	Fetal Kidney	kidney
41	chr15:74233000-74237600	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
42	chr15:74233200-74234600	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
43	chr15:74233200-74234800	Enhancers	HMEC	breast
44	chr15:74233200-74234800	Enhancers	NHEK	skin
45	chr15:74233200-74235000	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
46	chr15:74233200-74235000	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
47	chr15:74233200-74235000	Enhancers	HSMMtube	muscle
48	chr15:74233200-74235200	Enhancers	NHDF-Ad	bronchial
49	chr15:74233400-74234600	Enhancers	ES-I3 Cell Line	embryonic stem cell
50	chr15:74233400-74234800	Enhancers	NHLF	lung

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links