Variant report

Variant	rs11776589
Chromosome Location	chr8:124431432-124431433
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr8:124429815..124432313-chr8:124778028..124780178,2	K562	blood:
2	chr8:124429705..124433349-chr8:124436919..124438611,3	K562	blood:
3	chr8:124406056..124410111-chr8:124427174..124433258,8	MCF-7	breast:
4	chr8:124287117..124289356-chr8:124428879..124431490,3	MCF-7	breast:
5	chr8:124430051..124432680-chr8:124438774..124442383,3	K562	blood:
6	chr8:124405499..124410730-chr8:124426606..124431705,19	K562	blood:
7	chr8:124428532..124430498-chr8:124430799..124434472,3	MCF-7	breast:

Variant related genes	Relation type
ENSG00000165156	Chromatin interaction
ENSG00000156795	Chromatin interaction
ENSG00000156802	Chromatin interaction

Extended variants
information (count: 37 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:35)

rs_ID	r²[population]
rs10111271	0.98[AFR][1000 genomes];0.97[AMR][1000 genomes];0.95[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs10956126	0.98[AFR][1000 genomes];0.99[AMR][1000 genomes];0.95[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs11774702	0.90[AFR][1000 genomes];0.85[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs11783637	0.98[AFR][1000 genomes];0.99[AMR][1000 genomes];0.97[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs11787093	0.94[AFR][1000 genomes];0.92[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs12543979	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs12707901	0.90[AFR][1000 genomes];0.85[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs3779985	0.92[EUR][1000 genomes]
rs3779989	0.85[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs3779991	0.88[EUR][1000 genomes]
rs3857957	0.87[AFR][1000 genomes];0.83[AMR][1000 genomes];0.88[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs4006576	0.83[EUR][1000 genomes]
rs4870851	0.88[EUR][1000 genomes]
rs4871366	0.93[AFR][1000 genomes];0.93[AMR][1000 genomes];0.95[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4871367	0.92[AFR][1000 genomes];0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4871368	0.92[AFR][1000 genomes];0.91[AMR][1000 genomes];0.95[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4871370	0.98[AFR][1000 genomes];0.99[AMR][1000 genomes];0.95[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs4871371	0.98[AFR][1000 genomes];0.99[AMR][1000 genomes];0.95[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs4871373	0.98[AFR][1000 genomes];0.97[AMR][1000 genomes];0.95[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs4871377	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs62519216	0.91[EUR][1000 genomes]
rs6470146	0.87[EUR][1000 genomes]
rs6981304	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs6986525	0.91[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs6986901	0.86[EUR][1000 genomes]
rs6987599	0.84[EUR][1000 genomes]
rs7012343	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs72724211	0.88[ASN][1000 genomes]
rs72724214	0.88[ASN][1000 genomes]
rs7817573	0.84[EUR][1000 genomes]
rs7833321	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs7836626	0.93[AFR][1000 genomes];0.92[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7836880	0.83[AMR][1000 genomes];0.92[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7840703	0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs7844004	0.86[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv831449	chr8:124276685-124471740	Weak transcription Active TSS Genic enhancers Enhancers Flanking Active TSS Strong transcription Bivalent/Poised TSS Bivalent Enhancer Transcr. at gene 5' and 3' ZNF genes & repeats Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	42 gene(s)	inside rSNPs	diseases
2	esv3415547	chr8:124420820-124444289	Flanking Active TSS Strong transcription Enhancers Weak transcription Active TSS Bivalent/Poised TSS ZNF genes & repeats Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region	10 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs11776589	WDYHV1	cis	Heart Left Ventricle	GTEx

Chromatin state (count:115 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr8:124429800-124440800	Weak transcription	Aorta	Aorta
2	chr8:124430000-124431800	Enhancers	Brain Cingulate Gyrus	brain
3	chr8:124430000-124440400	Weak transcription	Fetal Stomach	stomach
4	chr8:124430000-124440600	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
5	chr8:124430000-124440600	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
6	chr8:124430000-124440800	Weak transcription	Primary monocytes fromperipheralblood	blood
7	chr8:124430000-124440800	Weak transcription	Left Ventricle	heart
8	chr8:124430000-124441000	Weak transcription	Lung	lung
9	chr8:124430000-124441400	Weak transcription	Primary B cells from cord blood	blood
10	chr8:124430000-124441600	Weak transcription	Thymus	Thymus
11	chr8:124430000-124443600	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
12	chr8:124430000-124443800	Weak transcription	Esophagus	oesophagus
13	chr8:124430000-124443800	Weak transcription	Right Ventricle	heart
14	chr8:124430000-124449200	Weak transcription	Small Intestine	intestine
15	chr8:124430000-124450200	Weak transcription	Brain Germinal Matrix	brain
16	chr8:124430200-124432400	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
17	chr8:124430200-124437000	Weak transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
18	chr8:124430200-124440600	Weak transcription	Primary B cells from peripheral blood	blood
19	chr8:124430200-124440600	Weak transcription	Adipose Nuclei	Adipose
20	chr8:124430200-124440800	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
21	chr8:124430200-124441000	Weak transcription	HUES64 Cell Line	embryonic stem cell
22	chr8:124430200-124441000	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
23	chr8:124430200-124441000	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
24	chr8:124430200-124441000	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
25	chr8:124430200-124441000	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
26	chr8:124430200-124441200	Weak transcription	HUES48 Cell Line	embryonic stem cell
27	chr8:124430200-124441200	Weak transcription	Rectal Mucosa Donor 29	rectum
28	chr8:124430200-124441400	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
29	chr8:124430200-124441400	Weak transcription	Fetal Muscle Leg	muscle
30	chr8:124430200-124441400	Weak transcription	Placenta	Placenta
31	chr8:124430200-124441400	Weak transcription	Rectal Mucosa Donor 31	rectum
32	chr8:124430200-124441400	Weak transcription	Monocytes-CD14+_RO01746	blood
33	chr8:124430200-124441600	Weak transcription	Fetal Brain Female	brain
34	chr8:124430200-124442200	Weak transcription	Rectal Smooth Muscle	rectum
35	chr8:124430200-124442200	Weak transcription	Stomach Smooth Muscle	stomach
36	chr8:124430200-124442600	Weak transcription	Gastric	stomach
37	chr8:124430200-124443600	Weak transcription	Ovary	ovary
38	chr8:124430200-124443600	Weak transcription	NH-A	brain
39	chr8:124430200-124443800	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
40	chr8:124430200-124443800	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
41	chr8:124430200-124443800	Weak transcription	Primary T cells from cord blood	blood
42	chr8:124430200-124443800	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
43	chr8:124430200-124443800	Weak transcription	Pancreas	Pancrea
44	chr8:124430200-124443800	Weak transcription	Spleen	Spleen
45	chr8:124430200-124443800	Weak transcription	HSMM	muscle
46	chr8:124430200-124447000	Weak transcription	iPS-15b Cell Line	embryonic stem cell
47	chr8:124430200-124448600	Weak transcription	NHEK	skin
48	chr8:124430200-124448600	Weak transcription	NHLF	lung
49	chr8:124430200-124448800	Weak transcription	NHDF-Ad	bronchial
50	chr8:124430200-124449000	Weak transcription	Osteobl	bone

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links