Variant report

Variant	rs274315
Chromosome Location	chr10:25241080-25241081
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	IRF1	chr10:25240388-25241107	K562	blood:	n/a	chr10:25240555-25240569 chr10:25241037-25241049
2	YY1	chr10:25240418-25241154	H1-hESC	embryonic stem cell:	n/a	n/a
3	POLR2A	chr10:25240578-25242391	MCF-7	breast:	n/a	n/a
4	MAX	chr10:25240852-25242106	GM12878	blood:	n/a	n/a
5	TAF1	chr10:25240585-25241128	K562	blood:	n/a	n/a
6	POLR2A	chr10:25241076-25242194	A549	lung:	n/a	n/a
7	POLR2A	chr10:25240388-25241196	K562	blood:	n/a	n/a
8	E2F6	chr10:25240834-25242460	A549	lung:	n/a	chr10:25241284-25241296 chr10:25241518-25241529 chr10:25241751-25241760 chr10:25241720-25241729 chr10:25241517-25241529 chr10:25241842-25241851 chr10:25241284-25241293 chr10:25241831-25241841 chr10:25241535-25241547 chr10:25241803-25241813 chr10:25241536-25241547
9	POLR2A	chr10:25240181-25244662	K562	blood:	n/a	n/a
10	BHLHE40	chr10:25240622-25242272	GM12878	blood:	n/a	chr10:25241832-25241848 chr10:25241803-25241819 chr10:25241723-25241739 chr10:25241792-25241808
11	MAX	chr10:25240740-25241287	K562	blood:	n/a	n/a
12	YY1	chr10:25240727-25241125	K562	blood:	n/a	n/a
13	UBTF	chr10:25240562-25242561	K562	blood:	n/a	n/a
14	CHD1	chr10:25241037-25241874	GM12878	blood:	n/a	chr10:25241723-25241733 chr10:25241285-25241295
15	E2F6	chr10:25240562-25242230	H1-hESC	embryonic stem cell:	n/a	chr10:25241284-25241296 chr10:25241518-25241529 chr10:25241751-25241760 chr10:25241720-25241729 chr10:25241517-25241529 chr10:25241842-25241851 chr10:25241284-25241293 chr10:25241831-25241841 chr10:25241535-25241547 chr10:25241803-25241813 chr10:25241536-25241547
16	MAX	chr10:25240488-25242348	H1-hESC	embryonic stem cell:	n/a	n/a
17	MYC	chr10:25240350-25242595	K562	blood:	n/a	n/a
18	POLR2A	chr10:25240548-25242157	Gliobla	brain:	n/a	n/a
19	CHD2	chr10:25241080-25242215	Hela-S3	cervix:	n/a	chr10:25241723-25241733 chr10:25241285-25241295
20	TAF7	chr10:25240518-25241172	H1-hESC	embryonic stem cell:	n/a	n/a
21	ZNF143	chr10:25240297-25242230	H1-hESC	embryonic stem cell:	n/a	chr10:25240833-25240851 chr10:25241686-25241696
22	HMGN3	chr10:25240572-25242067	K562	blood:	n/a	n/a
23	POLR2A	chr10:25240291-25242512	K562	blood:	n/a	n/a
24	EP300	chr10:25240384-25241120	K562	blood:	n/a	n/a
25	SIN3A	chr10:25240309-25242360	H1-hESC	embryonic stem cell:	n/a	chr10:25241794-25241807 chr10:25242209-25242218
26	UBTF	chr10:25240600-25242563	K562	blood:	n/a	n/a
27	ZMIZ1	chr10:25240569-25242628	K562	blood:	n/a	n/a
28	YY1	chr10:25240644-25242186	K562	blood:	n/a	chr10:25241842-25241851 chr10:25241803-25241817 chr10:25241837-25241851 chr10:25241805-25241814 chr10:25241284-25241293 chr10:25241797-25241811 chr10:25241834-25241848 chr10:25241714-25241723 chr10:25241802-25241811
29	POLR2A	chr10:25240583-25242147	GM19099	blood:	n/a	n/a
30	MYC	chr10:25240599-25242486	K562	blood:	n/a	n/a
31	PML	chr10:25240449-25241152	GM12878	blood:	n/a	n/a
32	POLR2A	chr10:25240175-25242598	H1-hESC	embryonic stem cell:	n/a	n/a
33	POLR2A	chr10:25240867-25241232	ProgFib	skin:	n/a	n/a
34	TAF1	chr10:25240656-25241207	K562	blood:	n/a	n/a
35	IRF1	chr10:25240541-25241156	K562	blood:	n/a	chr10:25240555-25240569 chr10:25241037-25241049
36	HEY1	chr10:25240615-25241127	K562	blood:	n/a	n/a
37	SMC3	chr10:25240491-25242275	Hela-S3	cervix:	n/a	chr10:25241807-25241821 chr10:25241807-25241817
38	CHD2	chr10:25240555-25242218	K562	blood:	n/a	chr10:25241723-25241733 chr10:25241285-25241295
39	IRF1	chr10:25240518-25241096	K562	blood:	n/a	chr10:25240555-25240569 chr10:25241037-25241049
40	POLR2A	chr10:25239865-25243383	GM12878	blood:	n/a	n/a
41	TCF12	chr10:25240710-25242361	A549	lung:	n/a	n/a
42	POLR2A	chr10:25240611-25241573	Hela-S3	cervix:	n/a	n/a
43	MAX	chr10:25240386-25242322	H1-hESC	embryonic stem cell:	n/a	n/a
44	CHD2	chr10:25240570-25242731	GM12878	blood:	n/a	chr10:25241723-25241733 chr10:25241285-25241295
45	MAX	chr10:25240502-25242429	A549	lung:	n/a	n/a
46	E2F4	chr10:25240662-25242177	K562	blood:	n/a	chr10:25241284-25241296 chr10:25241751-25241760 chr10:25241720-25241729 chr10:25241517-25241529 chr10:25241518-25241529 chr10:25241842-25241851 chr10:25241284-25241293 chr10:25241831-25241841 chr10:25241535-25241547 chr10:25241536-25241547 chr10:25241803-25241813
47	ZBTB7A	chr10:25240978-25241282	K562	blood:	n/a	n/a
48	HCFC1	chr10:25240564-25241974	K562	blood:	n/a	n/a
49	MAZ	chr10:25240241-25242685	K562	blood:	n/a	n/a
50	POLR2A	chr10:25240500-25242273	Hela-S3	cervix:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr10:25010748..25013945-chr10:25238648..25242767,8	MCF-7	breast:
2	chr10:25010212..25016288-chr10:25239162..25243925,7	K562	blood:
3	chr10:25009845..25014059-chr10:25240930..25243462,5	MCF-7	breast:
4	chr10:25009082..25014020-chr10:25238727..25242865,5	K562	blood:
5	chr10:25239754..25241501-chr10:25279969..25281607,2	K562	blood:
6	chr10:25239628..25245194-chr10:25304841..25307327,7	K562	blood:

Variant related genes	Relation type
ENSG00000273107	TF binding region
ENSG00000151023	Chromatin interaction
ENSG00000107863	Chromatin interaction
ENSG00000185875	Chromatin interaction

Extended variants
information (count: 2 )
Associated
traits (count: 0)

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1053278	chr10:25140776-25269093	Flanking Active TSS Enhancers Weak transcription Active TSS ZNF genes & repeats Strong transcription Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	7 gene(s)	inside rSNPs	diseases
2	esv3433843	chr10:25240746-25242744	Flanking Active TSS Enhancers Active TSS Transcr. at gene 5' and 3' Weak transcription Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	6 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:120 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:25237400-25241400	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
2	chr10:25237800-25241200	Weak transcription	Foreskin Melanocyte Primary Cells skin01	Skin
3	chr10:25240000-25241200	Flanking Active TSS	Ganglion Eminence derived primary cultured neurospheres	brain
4	chr10:25240000-25241200	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
5	chr10:25240000-25241200	Flanking Active TSS	Brain Germinal Matrix	brain
6	chr10:25240000-25241200	Enhancers	Spleen	Spleen
7	chr10:25240000-25241400	Enhancers	Fetal Heart	heart
8	chr10:25240200-25243000	Flanking Active TSS	Foreskin Fibroblast Primary Cells skin01	Skin
9	chr10:25240400-25242600	Active TSS	H9 Cell Line	embryonic stem cell
10	chr10:25240400-25242600	Flanking Active TSS	Dnd41	blood
11	chr10:25240600-25241200	Enhancers	Primary B cells from peripheral blood	blood
12	chr10:25240600-25241200	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
13	chr10:25240600-25241200	Enhancers	Primary T killer memory cells from peripheral blood	blood
14	chr10:25240600-25241200	Flanking Active TSS	Fetal Adrenal Gland	Adrenal Gland
15	chr10:25240600-25241200	Flanking Active TSS	Fetal Muscle Leg	muscle
16	chr10:25240600-25241200	Flanking Active TSS	Stomach Mucosa	stomach
17	chr10:25240600-25241200	Flanking Active TSS	NHLF	lung
18	chr10:25240600-25241400	Flanking Active TSS	IMR90 fetal lung fibroblasts Cell Line	lung
19	chr10:25240600-25241400	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Female	--
20	chr10:25240600-25241400	Flanking Active TSS	Muscle Satellite Cultured Cells	--
21	chr10:25240600-25241400	Flanking Active TSS	Foreskin Keratinocyte Primary Cells skin02	Skin
22	chr10:25240600-25241400	Flanking Active TSS	Foreskin Keratinocyte Primary Cells skin03	Skin
23	chr10:25240600-25241400	Flanking Active TSS	Adipose Nuclei	Adipose
24	chr10:25240600-25241400	Flanking Active TSS	Stomach Smooth Muscle	stomach
25	chr10:25240600-25241400	Flanking Active TSS	GM12878-XiMat	blood
26	chr10:25240600-25241400	Flanking Active TSS	Osteobl	bone
27	chr10:25240600-25241600	Flanking Active TSS	iPS DF 19.11 Cell Line	embryonic stem cell
28	chr10:25240600-25241600	Flanking Active TSS	Foreskin Fibroblast Primary Cells skin02	Skin
29	chr10:25240600-25242400	Active TSS	ES-UCSF4 Cell Line	embryonic stem cell
30	chr10:25240600-25242400	Active TSS	Rectal Mucosa Donor 29	rectum
31	chr10:25240600-25242400	Active TSS	Rectal Smooth Muscle	rectum
32	chr10:25240600-25242600	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
33	chr10:25240600-25242600	Flanking Active TSS	Cortex derived primary cultured neurospheres	brain
34	chr10:25240600-25242600	Active TSS	Pancreatic Islets	Pancreatic Islet
35	chr10:25240800-25241200	Flanking Active TSS	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
36	chr10:25240800-25241200	Flanking Active TSS	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
37	chr10:25240800-25241200	Flanking Active TSS	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
38	chr10:25240800-25241200	Flanking Active TSS	Breast Myoepithelial Primary Cells	Breast
39	chr10:25240800-25241200	Flanking Active TSS	Primary T helper memory cells from peripheral blood 2	blood
40	chr10:25240800-25241200	Flanking Active TSS	Fetal Thymus	thymus
41	chr10:25240800-25241200	Enhancers	HMEC	breast
42	chr10:25240800-25241200	Flanking Active TSS	NH-A	brain
43	chr10:25240800-25241400	Flanking Active TSS	Primary T cells fromperipheralblood	blood
44	chr10:25240800-25241400	Flanking Active TSS	Primary T helper cells fromperipheralblood	blood
45	chr10:25240800-25241400	Flanking Active TSS	Colonic Mucosa	Colon
46	chr10:25240800-25241400	Flanking Active TSS	Fetal Muscle Trunk	muscle
47	chr10:25240800-25241600	Flanking Bivalent TSS/Enh	Monocytes-CD14+_RO01746	blood
48	chr10:25240800-25241800	Active TSS	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
49	chr10:25240800-25241800	Active TSS	H9 Derived Neuron Cultured Cells	ES cell derived
50	chr10:25240800-25241800	Active TSS	Rectal Mucosa Donor 31	rectum

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links