Variant report

Variant	rs28525390
Chromosome Location	chr8:108513825-108513826
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	CEBPB	chr8:108513528-108513941	IMR90	lung:	n/a	n/a
2	FOS	chr8:108513542-108513929	MCF10A-Er-Src	breast:	n/a	chr8:108513725-108513736
3	FOS	chr8:108513572-108513915	MCF10A-Er-Src	breast:	n/a	chr8:108513725-108513736
4	FOS	chr8:108513586-108513906	MCF10A-Er-Src	breast:	n/a	chr8:108513725-108513736
5	MAFK	chr8:108513479-108513924	IMR90	lung:	n/a	n/a
6	FOS	chr8:108513539-108513991	HUVEC	blood vessel:	n/a	chr8:108513725-108513736
7	STAT3	chr8:108513701-108513896	MCF10A-Er-Src	breast:	n/a	n/a

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr8:108507981..108510207-chr8:108513209..108515922,2	K562	blood:
2	chr8:108510326..108512343-chr8:108512433..108514232,2	K562	blood:

Variant related genes	Relation type
ANGPT1	TF binding region

Extended variants
information (count: 15 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:12)

rs_ID	r²[population]
rs10099510	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs10101315	0.88[AFR][1000 genomes]
rs10102033	1.00[AMR][1000 genomes]
rs10216781	1.00[AMR][1000 genomes]
rs10441491	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs10441492	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs16876344	1.00[AMR][1000 genomes]
rs28477973	1.00[AMR][1000 genomes]
rs28521936	0.91[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs28752126	0.88[AFR][1000 genomes]
rs7814715	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs7839020	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	esv1845767	chr8:108504907-108515373	Enhancers Flanking Active TSS Weak transcription Active TSS Bivalent/Poised TSS Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region	1 gene(s)	inside rSNPs	diseases
2	esv1849422	chr8:108504907-108515373	Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Active TSS Weak transcription Bivalent/Poised TSS Bivalent Enhancer	TF binding region CpG island Chromatin interactive region	1 gene(s)	inside rSNPs	diseases
3	esv1825455	chr8:108504907-108518274	Bivalent/Poised TSS Flanking Active TSS Weak transcription Active TSS Enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region	1 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:25 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr8:108510400-108514000	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
2	chr8:108510400-108515000	Weak transcription	Left Ventricle	heart
3	chr8:108510400-108515200	Weak transcription	Ovary	ovary
4	chr8:108510600-108514200	Enhancers	Osteobl	bone
5	chr8:108511400-108514000	Enhancers	Primary hematopoietic stem cells short term culture	blood
6	chr8:108511800-108518600	Weak transcription	Fetal Kidney	kidney
7	chr8:108512000-108514000	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
8	chr8:108512200-108516000	Weak transcription	Aorta	Aorta
9	chr8:108512200-108517400	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
10	chr8:108512200-108518600	Weak transcription	Colon Smooth Muscle	Colon
11	chr8:108512200-108520200	Weak transcription	Psoas Muscle	Psoas
12	chr8:108512400-108515800	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
13	chr8:108512400-108516200	Weak transcription	Primary hematopoietic stem cells	blood
14	chr8:108512400-108521200	Weak transcription	Skeletal Muscle Male	skeletal muscle
15	chr8:108513000-108514200	Enhancers	Muscle Satellite Cultured Cells	--
16	chr8:108513200-108514200	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
17	chr8:108513400-108514000	Enhancers	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
18	chr8:108513400-108514000	Enhancers	NH-A	brain
19	chr8:108513600-108514000	Enhancers	Primary monocytes fromperipheralblood	blood
20	chr8:108513600-108514000	Enhancers	NHDF-Ad	bronchial
21	chr8:108513600-108514400	Enhancers	Monocytes-CD14+_RO01746	blood
22	chr8:108513600-108517400	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
23	chr8:108513800-108515400	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
24	chr8:108513800-108516400	Weak transcription	HSMM	muscle
25	chr8:108513800-108516600	Weak transcription	HUVEC	blood vessel

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