Variant report

Variant	rs436015
Chromosome Location	chr15:93208746-93208747
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr15:93207992..93209553-chr15:93211342..93213959,2	K562	blood:
2	chr15:93208505..93210593-chr15:93213536..93216229,2	K562	blood:

Extended variants
information (count: 14 )
Associated
traits (count: 2 )

rSNPs within LD-proxies of this variant (count:9)

rs_ID	r²[population]
rs11074093	0.81[ASN][1000 genomes]
rs11074094	0.87[EUR][1000 genomes];0.84[ASN][1000 genomes]
rs11852714	1.00[AMR][1000 genomes];0.97[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs11855078	1.00[AMR][1000 genomes];0.97[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs12440553	0.85[AMR][1000 genomes];0.88[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs12909879	0.98[AMR][1000 genomes];0.97[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs1532430	0.93[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs35156457	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs405737	0.92[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:5 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1037972	chr15:92804908-93270761	Flanking Bivalent TSS/Enh Enhancers Weak transcription Strong transcription Flanking Active TSS Bivalent Enhancer Active TSS ZNF genes & repeats Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
2	nsv904499	chr15:92914795-93472582	Bivalent Enhancer Flanking Active TSS Genic enhancers Strong transcription Active TSS Transcr. at gene 5' and 3' Weak transcription Enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	163 gene(s)	inside rSNPs	diseases
3	nsv948738	chr15:93070742-93728147	Strong transcription Weak transcription Flanking Active TSS Enhancers Genic enhancers Active TSS Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	169 gene(s)	inside rSNPs	diseases
4	nsv1049490	chr15:93134405-93591660	Enhancers Genic enhancers Weak transcription Strong transcription Active TSS ZNF genes & repeats Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	151 gene(s)	inside rSNPs	diseases
5	nsv1040501	chr15:93177153-93286393	Weak transcription Flanking Active TSS Enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Active TSS Bivalent/Poised TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	15 gene(s)	inside rSNPs	diseases

mRNA abundance (count:2)

SNP	Gene	Cis/trans	Tissue	Source
rs436015	FAM174B	cis	Esophagus Muscularis	GTEx
rs436015	LOC400451	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:71 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:93199600-93210000	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
2	chr15:93204000-93210600	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
3	chr15:93207200-93210200	Enhancers	Foreskin Melanocyte Primary Cells skin01	Skin
4	chr15:93207200-93211800	Enhancers	Fetal Muscle Trunk	muscle
5	chr15:93207200-93213000	Enhancers	Foreskin Melanocyte Primary Cells skin03	Skin
6	chr15:93207400-93210000	Enhancers	A549	lung
7	chr15:93207600-93208800	Enhancers	HUES64 Cell Line	embryonic stem cell
8	chr15:93207600-93209200	Enhancers	Brain Angular Gyrus	brain
9	chr15:93207600-93210200	Enhancers	iPS-18 Cell Line	embryonic stem cell
10	chr15:93207600-93211200	Enhancers	Pancreas	Pancrea
11	chr15:93207600-93211800	Enhancers	Fetal Muscle Leg	muscle
12	chr15:93207800-93208800	Enhancers	ES-I3 Cell Line	embryonic stem cell
13	chr15:93207800-93209400	Enhancers	Fetal Brain Male	brain
14	chr15:93207800-93210000	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
15	chr15:93207800-93211800	Enhancers	Liver	Liver
16	chr15:93207800-93211800	Enhancers	Fetal Stomach	stomach
17	chr15:93208000-93208800	Enhancers	Placenta	Placenta
18	chr15:93208000-93210200	Enhancers	iPS-20b Cell Line	embryonic stem cell
19	chr15:93208200-93208800	Enhancers	Brain Substantia Nigra	brain
20	chr15:93208200-93208800	Flanking Active TSS	Skeletal Muscle Male	skeletal muscle
21	chr15:93208200-93209000	Enhancers	HUES6 Cell Line	embryonic stem cell
22	chr15:93208200-93209000	Enhancers	iPS-15b Cell Line	embryonic stem cell
23	chr15:93208200-93209000	Enhancers	Breast Myoepithelial Primary Cells	Breast
24	chr15:93208200-93209000	Enhancers	HSMMtube	muscle
25	chr15:93208200-93209000	Bivalent Enhancer	K562	blood
26	chr15:93208200-93209600	Enhancers	Stomach Mucosa	stomach
27	chr15:93208200-93211800	Enhancers	Fetal Heart	heart
28	chr15:93208200-93212000	Enhancers	Fetal Intestine Small	intestine
29	chr15:93208400-93208800	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
30	chr15:93208400-93208800	Enhancers	H9 Derived Neuron Cultured Cells	ES cell derived
31	chr15:93208400-93208800	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
32	chr15:93208400-93208800	Enhancers	Primary hematopoietic stem cells	blood
33	chr15:93208400-93208800	Flanking Active TSS	Adipose Nuclei	Adipose
34	chr15:93208400-93208800	Active TSS	Colon Smooth Muscle	Colon
35	chr15:93208400-93208800	Active TSS	Pancreatic Islets	Pancreatic Islet
36	chr15:93208400-93208800	Active TSS	Fetal Lung	lung
37	chr15:93208400-93208800	Flanking Active TSS	Rectal Smooth Muscle	rectum
38	chr15:93208400-93208800	Active TSS	Right Atrium	heart
39	chr15:93208400-93208800	Active TSS	Skeletal Muscle Female	skeletal muscle
40	chr15:93208400-93209000	Flanking Active TSS	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
41	chr15:93208400-93209000	Flanking Active TSS	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
42	chr15:93208400-93209000	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
43	chr15:93208400-93209000	Enhancers	Muscle Satellite Cultured Cells	--
44	chr15:93208400-93209000	Enhancers	Brain Cingulate Gyrus	brain
45	chr15:93208400-93209000	Enhancers	Brain Hippocampus Middle	brain
46	chr15:93208400-93209000	Flanking Active TSS	GM12878-XiMat	blood
47	chr15:93208400-93209200	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
48	chr15:93208400-93209400	Weak transcription	Fetal Intestine Large	intestine
49	chr15:93208400-93209400	Weak transcription	Left Ventricle	heart
50	chr15:93208400-93209400	Weak transcription	Ovary	ovary

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links