Variant report

Variant	rs4886633
Chromosome Location	chr15:75178207-75178208
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr15:75176018..75178880-chr15:75197656..75199234,2	MCF-7	breast:
2	chr15:75166310..75168984-chr15:75177329..75180043,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000178761	Chromatin interaction

Extended variants
information (count: 21 )
Associated
traits (count: 3 )

rSNPs within LD-proxies of this variant (count:20)

rs_ID	r²[population]
rs12906946	0.94[AMR][1000 genomes];0.90[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs12911781	0.86[AFR][1000 genomes];0.86[AMR][1000 genomes];0.96[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs12914369	0.84[AFR][1000 genomes];0.84[AMR][1000 genomes];0.93[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs1869959	0.87[CEU][hapmap];0.83[YRI][hapmap]
rs4886615	0.83[CEU][hapmap]
rs6495124	0.83[AFR][1000 genomes];0.94[AMR][1000 genomes];0.94[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs6495126	1.00[CEU][hapmap];0.89[YRI][hapmap];0.95[AFR][1000 genomes];0.95[AMR][1000 genomes];0.97[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs6495127	1.00[CEU][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.98[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs6495131	0.86[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs67411922	1.00[AFR][1000 genomes];0.95[AMR][1000 genomes];0.98[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs7174968	0.80[AFR][1000 genomes];0.88[AMR][1000 genomes];0.98[EUR][1000 genomes]
rs7495033	0.91[EUR][1000 genomes]
rs7497201	1.00[CEU][hapmap];1.00[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs8025890	0.81[AFR][1000 genomes]
rs8031937	1.00[CEU][hapmap];1.00[YRI][hapmap];0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs8042694	0.95[CEU][hapmap];0.84[YRI][hapmap];0.80[AFR][1000 genomes];0.92[AMR][1000 genomes];0.97[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs9210	0.83[CEU][hapmap]
rs936228	0.83[CEU][hapmap]
rs936229	0.83[CEU][hapmap]
rs936230	0.87[CEU][hapmap]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv904381	chr15:75108636-75242155	Weak transcription Genic enhancers Enhancers Flanking Active TSS Active TSS Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	55 gene(s)	inside rSNPs	diseases

mRNA abundance (count:3)

SNP	Gene	Cis/trans	Tissue	Source
rs4886633	MPI	Cis_1M	lymphoblastoid	RTeQTL
rs4886633	ULK3	cis	Whole Blood	GTEx
rs4886633	MPI	cis	multi-tissue	Pritchard

Chromatin state (count:50 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:75166200-75181000	Weak transcription	Fetal Heart	heart
2	chr15:75175200-75181000	Weak transcription	Spleen	Spleen
3	chr15:75175400-75181200	Weak transcription	H9 Cell Line	embryonic stem cell
4	chr15:75175600-75179200	Enhancers	Primary monocytes fromperipheralblood	blood
5	chr15:75176400-75179000	Enhancers	Primary hematopoietic stem cells short term culture	blood
6	chr15:75176600-75178800	Weak transcription	Rectal Mucosa Donor 31	rectum
7	chr15:75176800-75178600	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
8	chr15:75176800-75178600	Enhancers	Monocytes-CD14+_RO01746	blood
9	chr15:75176800-75181200	Weak transcription	Rectal Mucosa Donor 29	rectum
10	chr15:75176800-75181400	Weak transcription	Primary hematopoietic stem cells	blood
11	chr15:75176800-75181800	Weak transcription	A549	lung
12	chr15:75177000-75181200	Weak transcription	Primary T helper cells PMA-I stimulated	--
13	chr15:75177000-75181800	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
14	chr15:75177200-75181000	Weak transcription	HUES6 Cell Line	embryonic stem cell
15	chr15:75177200-75181400	Weak transcription	Primary T cells fromperipheralblood	blood
16	chr15:75177200-75181600	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
17	chr15:75177200-75181800	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
18	chr15:75177400-75179600	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
19	chr15:75177400-75181000	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
20	chr15:75177400-75181200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
21	chr15:75177400-75181200	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
22	chr15:75177400-75181200	Weak transcription	NH-A	brain
23	chr15:75177400-75181400	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
24	chr15:75177400-75181400	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
25	chr15:75177400-75181600	Weak transcription	Primary B cells from peripheral blood	blood
26	chr15:75177600-75181000	Weak transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
27	chr15:75177600-75181000	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
28	chr15:75177600-75181000	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
29	chr15:75177600-75181000	Weak transcription	HepG2	liver
30	chr15:75177600-75181200	Weak transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
31	chr15:75177600-75181200	Weak transcription	GM12878-XiMat	blood
32	chr15:75177600-75181400	Weak transcription	Primary T helper cells fromperipheralblood	blood
33	chr15:75177600-75181400	Weak transcription	HSMMtube	muscle
34	chr15:75177600-75181400	Weak transcription	NHLF	lung
35	chr15:75177600-75181400	Weak transcription	Osteobl	bone
36	chr15:75177800-75181000	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
37	chr15:75177800-75181000	Weak transcription	Placenta	Placenta
38	chr15:75177800-75181400	Weak transcription	Muscle Satellite Cultured Cells	--
39	chr15:75177800-75181400	Weak transcription	Hela-S3	cervix
40	chr15:75177800-75181600	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
41	chr15:75178000-75178800	Enhancers	Fetal Intestine Small	intestine
42	chr15:75178000-75181000	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
43	chr15:75178000-75181000	Weak transcription	Adipose Nuclei	Adipose
44	chr15:75178000-75181200	Weak transcription	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
45	chr15:75178000-75181200	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
46	chr15:75178000-75181200	Weak transcription	NHEK	skin
47	chr15:75178000-75181400	Weak transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
48	chr15:75178000-75181400	Weak transcription	HMEC	breast
49	chr15:75178000-75181400	Weak transcription	HSMM	muscle
50	chr15:75178200-75181200	Weak transcription	NHDF-Ad	bronchial

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