Variant report
| Variant | rs7110046 |
|---|---|
| Chromosome Location | chr11:94129344-94129345 |
| allele | C/T |
| Outlinks | Ensembl UCSC |
- TF binding region (count:0)
- CpG islands (count:0)
- Chromatin interactive region (count:0)
- LncRNA region (count:0)
- Mature miRNA region (count: 0)
- miRNA target sites (count:0)
| No data |
| No data |
| No data |
| No data |
| No data |
| No data |
| No data |
rSNPs within LD-proxies of this variant (count:18)
| rs_ID | r2[population] |
|---|---|
| rs11020767 | 0.94[AMR][1000 genomes];0.90[EUR][1000 genomes];1.00[ASN][1000 genomes] |
| rs13447646 | 0.82[AMR][1000 genomes];0.82[EUR][1000 genomes] |
| rs512150 | 0.81[AMR][1000 genomes];0.82[EUR][1000 genomes] |
| rs516381 | 0.97[AMR][1000 genomes];0.94[EUR][1000 genomes];0.97[ASN][1000 genomes] |
| rs521669 | 0.96[AMR][1000 genomes];0.91[EUR][1000 genomes] |
| rs522596 | 0.83[AMR][1000 genomes] |
| rs540514 | 0.93[AMR][1000 genomes];0.88[EUR][1000 genomes] |
| rs547289 | 0.99[AMR][1000 genomes];0.94[EUR][1000 genomes];0.99[ASN][1000 genomes] |
| rs552126 | 0.82[AMR][1000 genomes];0.82[EUR][1000 genomes] |
| rs581002 | 0.93[AMR][1000 genomes];0.93[EUR][1000 genomes] |
| rs584707 | 0.96[AMR][1000 genomes];0.88[EUR][1000 genomes] |
| rs59678918 | 0.84[AFR][1000 genomes] |
| rs598599 | 0.85[AMR][1000 genomes];0.82[EUR][1000 genomes] |
| rs603937 | 0.83[AMR][1000 genomes] |
| rs607146 | 0.81[AMR][1000 genomes] |
| rs607974 | 0.81[AMR][1000 genomes] |
| rs663530 | 0.96[AMR][1000 genomes];0.93[EUR][1000 genomes] |
| rs687109 | 0.86[AMR][1000 genomes];0.82[EUR][1000 genomes] |
Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page:
1
| No. | Variant name | Chromosome position | Chromatin state | Related regulatory elements | Target genes | Extended variants | Associated traits |
|---|---|---|---|---|---|---|---|
| 1 | nsv523083 | chr11:93962121-94150790 | Flanking Bivalent TSS/Enh Weak transcription Bivalent Enhancer Enhancers ZNF genes & repeats Strong transcription Bivalent/Poised TSS Flanking Active TSS Active TSS Genic enhancers | TF binding regionCpG islandChromatin interactive regionlncRNAmiRNA target site | 6 gene(s) | inside rSNPs | diseases |
| 2 | nsv832233 | chr11:93981434-94158471 | Enhancers Flanking Bivalent TSS/Enh Weak transcription Active TSS Bivalent Enhancer Bivalent/Poised TSS Strong transcription Flanking Active TSS ZNF genes & repeats Genic enhancers | TF binding regionCpG islandChromatin interactive regionlncRNAmiRNA target site | 5 gene(s) | inside rSNPs | diseases |
mRNA abundance (count:22)
| SNP | Gene | Cis/trans | Tissue | Source |
|---|---|---|---|---|
| rs7110046 | MRE11A | cis | Nerve Tibial | GTEx |
| rs7110046 | RP11-685N10.1 | cis | lung | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Esophagus Mucosa | GTEx |
| rs7110046 | MRE11A | cis | Esophagus Mucosa | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Heart Left Ventricle | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Artery Tibial | GTEx |
| rs7110046 | MRE11A | cis | Stomach | GTEx |
| rs7110046 | MRE11A | cis | Whole Blood | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Esophagus Muscularis | GTEx |
| rs7110046 | MRE11A | cis | lung | GTEx |
| rs7110046 | MRE11A | cis | Heart Left Ventricle | GTEx |
| rs7110046 | MRE11A | cis | Artery Tibial | GTEx |
| rs7110046 | MRE11A | Cis_1M | lymphoblastoid | RTeQTL |
| rs7110046 | RP11-685N10.1 | cis | Nerve Tibial | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Skin Sun Exposed Lower leg | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Muscle Skeletal | GTEx |
| rs7110046 | MRE11A | cis | Thyroid | GTEx |
| rs7110046 | MRE11A | cis | Esophagus Muscularis | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Adipose Subcutaneous | GTEx |
| rs7110046 | MRE11A | cis | Skin Sun Exposed Lower leg | GTEx |
| rs7110046 | RP11-685N10.1 | cis | Thyroid | GTEx |
| rs7110046 | MRE11A | cis | Adipose Subcutaneous | GTEx |
| No. | Chromosome Location | Chromatin state | Cell line | Tissue |
|---|---|---|---|---|
| 1 | chr11:94119600-94132400 | Weak transcription | H1 BMP4 Derived Mesendoderm Cultured Cells | ES cell derived |
