Variant report

Variant	esv1839810
Chromosome Location	chr10:28656826-28665006
allele	n/a
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:28663936..28666501-chr10:28668438..28671380,2	MCF-7	breast:
2	chr10:28591813..28593697-chr10:28661899..28664079,2	MCF-7	breast:
3	chr10:28592071..28593938-chr10:28656842..28659307,2	MCF-7	breast:
4	chr10:28591043..28593687-chr10:28664623..28666439,2	MCF-7	breast:
5	chr10:28591610..28593155-chr10:28664575..28666519,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000150054	chromatin interactions

Extended variants
information (count: 356 )
Associated
traits (count: 41 )

Variant overlapped rSNPs/rCNVs (count:356 , 50 per page) page: 1 2 3 4 5 6 7 8

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	rs12783789	chr10:28656826-28656827	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	mRNA abundance
2	rs376351823	chr10:28656828-28656829	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
3	rs574965640	chr10:28656843-28656844	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
4	rs554827745	chr10:28656851-28656852	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
5	rs576357914	chr10:28656863-28656864	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
6	rs543969571	chr10:28656865-28656866	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
7	rs116570629	chr10:28656878-28656879	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
8	rs4749321	chr10:28656906-28656907	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
9	rs577629158	chr10:28656986-28656987	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
10	rs544782343	chr10:28656987-28656988	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
11	rs560339457	chr10:28657001-28657002	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
12	rs572052980	chr10:28657021-28657022	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
13	rs542669827	chr10:28657171-28657172	Enhancers Weak transcription Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
14	rs561136242	chr10:28657270-28657271	Weak transcription Enhancers Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
15	rs529021174	chr10:28657271-28657272	Weak transcription Enhancers Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
16	rs549906000	chr10:28657281-28657282	Weak transcription Enhancers Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
17	rs564934796	chr10:28657316-28657317	Weak transcription Enhancers Bivalent Enhancer Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
18	rs117964163	chr10:28657409-28657410	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
19	rs183174542	chr10:28657471-28657472	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
20	rs147391729	chr10:28657473-28657474	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
21	rs536225035	chr10:28657510-28657511	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
22	rs548200851	chr10:28657546-28657547	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
23	rs187586108	chr10:28657551-28657552	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
24	rs536215204	chr10:28657567-28657568	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
25	rs537355846	chr10:28657602-28657603	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
26	rs559063794	chr10:28657603-28657604	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
27	rs577365310	chr10:28657609-28657610	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
28	rs535264636	chr10:28657610-28657611	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
29	rs553878886	chr10:28657617-28657618	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
30	rs572190400	chr10:28657624-28657625	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
31	rs192197018	chr10:28657633-28657634	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
32	rs185107158	chr10:28657655-28657656	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
33	rs189626975	chr10:28657663-28657664	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
34	rs543347971	chr10:28657670-28657671	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
35	rs565224244	chr10:28657692-28657693	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
36	rs1249266	chr10:28657705-28657706	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	LD-proxies of rSNP Overlapped rCNV	n/a
37	rs547218508	chr10:28657717-28657718	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
38	rs559394101	chr10:28657718-28657719	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
39	rs530151530	chr10:28657719-28657720	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
40	rs192897007	chr10:28657748-28657749	Weak transcription Enhancers Flanking Active TSS	n/a	n/a	Overlapped CNVs	n/a
41	rs184542972	chr10:28657825-28657826	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
42	rs188201375	chr10:28657863-28657864	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
43	rs552588715	chr10:28657872-28657873	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
44	rs57369828	chr10:28657922-28657923	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
45	rs397826714	chr10:28657927-28657928	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
46	rs182033427	chr10:28657971-28657972	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
47	rs370998360	chr10:28657975-28657976	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
48	rs71391031	chr10:28657995-28657996	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
49	rs79252147	chr10:28657996-28657997	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a
50	rs535200209	chr10:28658001-28658002	Weak transcription Enhancers	n/a	n/a	Overlapped CNVs	n/a

Variant related diseases (count:41)

Disease	PMID	Source
Breast cancer	17133270	CNVD
Endometrioid adenocarcinoma	16974079	CNVD
Breast cancer	17603634	CNVD
Endometrial cancer	22040021	CNVD
Glioblastoma multiforme	21080181	CNVD
Breast cancer	21264507	CNVD
Esophageal squamous carcinoma	21637470	CNVD
Phyllodes tumor	17334353	CNVD
Acute lymphoblastic leukemia	17690704	CNVD
Pancreatic endocrine tumor	17639061	CNVD
Gastric cancer	17908304	CNVD
Chordoma	21602918	CNVD
Ewing''s sarcoma	21437220	CNVD
Medulloblastoma	21979893	CNVD
Melanoma	18172304	CNVD
Pleomorphic xanthoastrocytoma	20730472	CNVD
Lung cancer	18438408	CNVD
Thoracic aortic aneurysm	21092924	CNVD
Ewing''s sarcoma	17952124	CNVD
Oral cancer	21386901	CNVD
Acute lymphoblastic leukemia	20435627	CNVD
T-cell prolymphocytic leukemia	19278963	CNVD
Hodgkin''s lymphoma	17606441	CNVD
Breast cancer	21858162	CNVD
Acute lymphoblastic leukemia	20724749	CNVD
Autism	22495311	CNVD
T-cell lymphomas	19863542	CNVD
Esophageal cancer	21851588	CNVD
Behavioral abnormalities	21522184	CNVD
Dysmorphic features	21522184	CNVD
low-grade B-cell lymphoma tumor	18367492	CNVD
Ovine squamous-cell carcinoma	17599052	CNVD
T-cell acute lymphoblastic leukemia	18185524	CNVD
Oral squamous cell carcinoma	17134496	CNVD
Breast cancer	21364760	CNVD
abnormal development	18461090	CNVD
T-cell prolymphocytic leukemia	17713554	CNVD
small cell lung cancer	20016488	CNVD
Breast cancer	22048815	CNVD
Myelofibrosis	22110671	CNVD
Chronic lymphocytic leukemia	21546498	CNVD

Chromatin state (count:140 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:28644400-28665000	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
2	chr10:28653600-28658400	Enhancers	Fetal Intestine Large	intestine
3	chr10:28654000-28657600	Enhancers	Fetal Intestine Small	intestine
4	chr10:28654000-28658800	Enhancers	Primary B cells from peripheral blood	blood
5	chr10:28654200-28660400	Enhancers	Primary monocytes fromperipheralblood	blood
6	chr10:28654600-28657200	Enhancers	Primary mononuclear cells fromperipheralblood	Blood
7	chr10:28654600-28657400	Enhancers	Stomach Mucosa	stomach
8	chr10:28654800-28657200	Enhancers	Thymus	Thymus
9	chr10:28655000-28659600	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
10	chr10:28655200-28657600	Enhancers	Primary hematopoietic stem cells	blood
11	chr10:28655400-28657000	Enhancers	Rectal Mucosa Donor 31	rectum
12	chr10:28655400-28657600	Enhancers	Sigmoid Colon	Sigmoid Colon
13	chr10:28655400-28657800	Enhancers	Fetal Thymus	thymus
14	chr10:28655400-28658000	Enhancers	HepG2	liver
15	chr10:28655400-28658800	Enhancers	Primary Natural Killer cells fromperipheralblood	blood
16	chr10:28655800-28657400	Enhancers	Fetal Muscle Leg	muscle
17	chr10:28655800-28658000	Enhancers	Primary hematopoietic stem cells short term culture	blood
18	chr10:28656000-28657000	Enhancers	Lung	lung
19	chr10:28656000-28657200	Flanking Active TSS	Monocytes-CD14+_RO01746	blood
20	chr10:28656000-28657400	Enhancers	Small Intestine	intestine
21	chr10:28656200-28657000	Bivalent Enhancer	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
22	chr10:28656200-28657200	Enhancers	ES-I3 Cell Line	embryonic stem cell
23	chr10:28656200-28657200	Flanking Active TSS	Primary T helper naive cells from peripheral blood	blood
24	chr10:28656200-28657200	Enhancers	Placenta	Placenta
25	chr10:28656200-28657800	Flanking Active TSS	Primary neutrophils fromperipheralblood	blood
26	chr10:28656200-28661800	Weak transcription	Colonic Mucosa	Colon
27	chr10:28656400-28657200	Flanking Active TSS	Primary T helper memory cells from peripheral blood 2	blood
28	chr10:28656400-28657200	Enhancers	Liver	Liver
29	chr10:28656400-28657200	Enhancers	GM12878-XiMat	blood
30	chr10:28656600-28657400	Flanking Active TSS	Primary T helper cells PMA-I stimulated	--
31	chr10:28656600-28657600	Flanking Active TSS	Primary T helper cells fromperipheralblood	blood
32	chr10:28656600-28657800	Enhancers	Fetal Muscle Trunk	muscle
33	chr10:28656800-28657000	Flanking Active TSS	Primary T helper 17 cells PMA-I stimulated	--
34	chr10:28656800-28657000	Flanking Active TSS	Primary T regulatory cells fromperipheralblood	blood
35	chr10:28656800-28657200	Flanking Active TSS	Primary B cells from cord blood	blood
36	chr10:28656800-28657200	Flanking Active TSS	Primary T cells fromperipheralblood	blood
37	chr10:28656800-28657200	Flanking Active TSS	Primary T killer naive cells fromperipheralblood	blood
38	chr10:28656800-28657200	Flanking Active TSS	Primary T killer memory cells from peripheral blood	blood
39	chr10:28656800-28657200	Enhancers	Placenta Amnion	Placenta Amnion
40	chr10:28656800-28657400	Bivalent Enhancer	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
41	chr10:28656800-28657400	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Female	--
42	chr10:28656800-28657400	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
43	chr10:28656800-28657400	Enhancers	Duodenum Mucosa	Duodenum
44	chr10:28656800-28657800	Flanking Active TSS	Primary T cells from cord blood	blood
45	chr10:28656800-28658600	Enhancers	Primary T cells effector/memory enriched fromperipheralblood	blood
46	chr10:28656800-28659800	Enhancers	Primary T helper naive cells fromperipheralblood	blood
47	chr10:28657000-28657200	Enhancers	Primary T helper 17 cells PMA-I stimulated	--
48	chr10:28657000-28657200	Enhancers	Primary T regulatory cells fromperipheralblood	blood
49	chr10:28657000-28657400	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
50	chr10:28657200-28657400	Enhancers	iPS-18 Cell Line	embryonic stem cell

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links