Variant report

Variant	rs11186726
Chromosome Location	chr10:93648327-93648328
allele	A/C
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr10:93643244..93645164-chr10:93648326..93650268,2	MCF-7	breast:
2	chr10:93645639..93650363-chr10:93664527..93668609,7	MCF-7	breast:

Variant related genes	Relation type
ENSG00000272817	Chromatin interaction

Extended variants
information (count: 27 )
Associated
traits (count: 12 )

rSNPs within LD-proxies of this variant (count:25)

rs_ID	r²[population]
rs10748568	0.80[CEU][hapmap];0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.80[AMR][1000 genomes]
rs10748569	0.80[AMR][1000 genomes]
rs10786018	0.80[CEU][hapmap];0.92[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.80[AMR][1000 genomes]
rs10881959	0.86[CHB][hapmap];1.00[JPT][hapmap];0.87[YRI][hapmap]
rs11186695	0.80[AMR][1000 genomes]
rs11186731	0.81[AMR][1000 genomes];0.87[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs12248932	0.88[CEU][hapmap];0.93[CHB][hapmap];0.82[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs1340420	0.80[CEU][hapmap];0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.80[AFR][1000 genomes];0.83[AMR][1000 genomes]
rs1539041	0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap]
rs1770467	0.83[AMR][1000 genomes]
rs1770470	0.81[CEU][hapmap];0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.80[AFR][1000 genomes];0.80[AMR][1000 genomes]
rs1770472	0.80[AFR][1000 genomes];0.83[AMR][1000 genomes]
rs1772180	0.80[AFR][1000 genomes];0.80[AMR][1000 genomes]
rs1772185	0.80[AFR][1000 genomes];0.80[AMR][1000 genomes]
rs1935030	0.81[CEU][hapmap];0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap];0.80[AMR][1000 genomes]
rs2066276	0.80[CEU][hapmap];0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap]
rs2259280	0.80[AFR][1000 genomes];0.84[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs2487513	0.80[AFR][1000 genomes];0.80[AMR][1000 genomes]
rs2487514	0.85[AMR][1000 genomes]
rs2994394	0.80[AFR][1000 genomes];0.85[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs6583787	0.93[CHB][hapmap];1.00[JPT][hapmap];1.00[YRI][hapmap]
rs66627345	0.88[AMR][1000 genomes];0.90[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs7079825	0.88[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs7085519	0.88[CEU][hapmap];0.93[CHB][hapmap];1.00[JPT][hapmap];0.82[AMR][1000 genomes];0.81[ASN][1000 genomes]
rs946896	0.80[AFR][1000 genomes];0.80[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv7491	chr10:93626192-93671694	Enhancers Weak transcription Active TSS Flanking Active TSS Bivalent Enhancer Strong transcription Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	7 gene(s)	inside rSNPs	diseases
2	esv1842657	chr10:93634155-93668663	Flanking Active TSS Enhancers Weak transcription Active TSS ZNF genes & repeats Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Genic enhancers Bivalent Enhancer Bivalent/Poised TSS Strong transcription	TF binding region CpG island Chromatin interactive region lncRNA	7 gene(s)	inside rSNPs	diseases

mRNA abundance (count:12)

SNP	Gene	Cis/trans	Tissue	Source
rs11186726	TNKS2-AS1	cis	Stomach	GTEx
rs11186726	TNKS2-AS1	cis	Muscle Skeletal	GTEx
rs11186726	TNKS2-AS1	cis	Artery Tibial	GTEx
rs11186726	TNKS2-AS1	cis	Esophagus Mucosa	GTEx
rs11186726	TNKS2-AS1	cis	Heart Left Ventricle	GTEx
rs11186726	TNKS2-AS1	cis	Nerve Tibial	GTEx
rs11186726	TNKS2-AS1	cis	lung	GTEx
rs11186726	TNKS2-AS1	cis	Adipose Subcutaneous	GTEx
rs11186726	TNKS2-AS1	cis	Skin Sun Exposed Lower leg	GTEx
rs11186726	TNKS2-AS1	cis	Esophagus Muscularis	GTEx
rs11186726	TNKS2-AS1	cis	Artery Aorta	GTEx
rs11186726	TNKS2-AS1	cis	Thyroid	GTEx

Chromatin state (count:45 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:93644200-93648600	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
2	chr10:93645800-93649400	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
3	chr10:93646600-93648400	Enhancers	ES-UCSF4 Cell Line	embryonic stem cell
4	chr10:93647400-93667800	Weak transcription	Spleen	Spleen
5	chr10:93647600-93648800	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
6	chr10:93647600-93649400	Weak transcription	H9 Cell Line	embryonic stem cell
7	chr10:93647600-93649600	Weak transcription	iPS DF 19.11 Cell Line	embryonic stem cell
8	chr10:93647600-93651600	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
9	chr10:93647800-93648400	Enhancers	H1 Cell Line	embryonic stem cell
10	chr10:93647800-93648400	Enhancers	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
11	chr10:93647800-93648400	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
12	chr10:93647800-93648400	Enhancers	Cortex derived primary cultured neurospheres	brain
13	chr10:93647800-93648600	Enhancers	HUES48 Cell Line	embryonic stem cell
14	chr10:93647800-93648800	Enhancers	H9 Derived Neuron Cultured Cells	ES cell derived
15	chr10:93647800-93649600	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
16	chr10:93647800-93650000	Enhancers	iPS-18 Cell Line	embryonic stem cell
17	chr10:93647800-93650200	Weak transcription	Pancreas	Pancrea
18	chr10:93647800-93651000	Enhancers	HUES64 Cell Line	embryonic stem cell
19	chr10:93648000-93648400	Enhancers	ES-I3 Cell Line	embryonic stem cell
20	chr10:93648000-93648400	Enhancers	HUES6 Cell Line	embryonic stem cell
21	chr10:93648000-93648400	Enhancers	iPS-15b Cell Line	embryonic stem cell
22	chr10:93648000-93648400	Enhancers	Breast Myoepithelial Primary Cells	Breast
23	chr10:93648000-93648400	Bivalent Enhancer	Primary T cells from cord blood	blood
24	chr10:93648000-93648400	Enhancers	Primary hematopoietic stem cells short term culture	blood
25	chr10:93648000-93648400	Enhancers	Primary T helper cells PMA-I stimulated	--
26	chr10:93648000-93648400	Enhancers	Primary T helper cells fromperipheralblood	blood
27	chr10:93648000-93648400	Enhancers	Primary T killer naive cells fromperipheralblood	blood
28	chr10:93648000-93648400	Enhancers	Ganglion Eminence derived primary cultured neurospheres	brain
29	chr10:93648000-93648400	Enhancers	Fetal Brain Male	brain
30	chr10:93648000-93648400	Enhancers	Fetal Kidney	kidney
31	chr10:93648000-93648400	Enhancers	Fetal Lung	lung
32	chr10:93648000-93649600	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
33	chr10:93648000-93649800	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
34	chr10:93648000-93649800	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
35	chr10:93648000-93650400	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
36	chr10:93648000-93650400	Weak transcription	HepG2	liver
37	chr10:93648000-93650400	Weak transcription	NHDF-Ad	bronchial
38	chr10:93648000-93650600	Weak transcription	Muscle Satellite Cultured Cells	--
39	chr10:93648000-93650600	Weak transcription	A549	lung
40	chr10:93648000-93650600	Weak transcription	HUVEC	blood vessel
41	chr10:93648000-93650600	Weak transcription	NHLF	lung
42	chr10:93648000-93651400	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
43	chr10:93648000-93651400	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
44	chr10:93648000-93651400	Weak transcription	Foreskin Melanocyte Primary Cells skin03	Skin
45	chr10:93648200-93648600	Enhancers	iPS-20b Cell Line	embryonic stem cell

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links