Variant report

Variant	rs11227591
Chromosome Location	chr11:66529971-66529972
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	CTCF	chr11:66529880-66530030	GM12875	blood:	n/a	n/a

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr11:66526435..66528204-chr11:66529926..66531450,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000213409	TF binding region
ENSG00000173715	Chromatin interaction

Extended variants
information (count: 16 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:7)

rs_ID	r²[population]
rs11227574	0.84[ASN][1000 genomes]
rs11227587	1.00[ASN][1000 genomes]
rs11227600	0.85[AFR][1000 genomes];0.97[ASN][1000 genomes]
rs11227601	0.85[AFR][1000 genomes];0.97[ASN][1000 genomes]
rs12049897	0.81[ASN][1000 genomes]
rs12225302	0.92[ASN][1000 genomes]
rs2276136	0.81[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:9 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv897789	chr11:66372390-66634397	Weak transcription Enhancers Active TSS Flanking Active TSS Transcr. at gene 5' and 3' Strong transcription Genic enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer ZNF genes & repeats Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	117 gene(s)	inside rSNPs	diseases
2	nsv897790	chr11:66414915-66626234	Transcr. at gene 5' and 3' Strong transcription Weak transcription Active TSS Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Genic enhancers Bivalent Enhancer Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	75 gene(s)	inside rSNPs	diseases
3	nsv897791	chr11:66442855-66533469	Weak transcription Strong transcription Enhancers Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3' Active TSS Flanking Active TSS Bivalent/Poised TSS Flanking Bivalent TSS/Enh ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	49 gene(s)	inside rSNPs	diseases
4	nsv427891	chr11:66456140-66606701	Enhancers Weak transcription Strong transcription Genic enhancers Flanking Bivalent TSS/Enh Flanking Active TSS Active TSS Bivalent Enhancer Bivalent/Poised TSS Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	36 gene(s)	inside rSNPs	diseases
5	nsv468602	chr11:66468469-66634397	Enhancers Active TSS Strong transcription Genic enhancers Flanking Active TSS Bivalent Enhancer Weak transcription Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent/Poised TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	70 gene(s)	inside rSNPs	diseases
6	nsv555225	chr11:66468469-66634397	Weak transcription Enhancers Flanking Active TSS Genic enhancers Strong transcription Active TSS Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	70 gene(s)	inside rSNPs	diseases
7	nsv897793	chr11:66486143-66533469	Enhancers Weak transcription Active TSS Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent Enhancer ZNF genes & repeats Bivalent/Poised TSS Strong transcription Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	29 gene(s)	inside rSNPs	diseases
8	esv1798614	chr11:66514847-66535177	Weak transcription Strong transcription Enhancers Genic enhancers ZNF genes & repeats Flanking Active TSS Active TSS	TF binding region CpG island Chromatin interactive region lncRNA	8 gene(s)	inside rSNPs	diseases
9	nsv516087	chr11:66516049-66579572	Weak transcription Enhancers Strong transcription ZNF genes & repeats Genic enhancers Active TSS Flanking Active TSS	TF binding region CpG island Chromatin interactive region lncRNA	11 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:85 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:66513200-66530800	Weak transcription	HSMMtube	muscle
2	chr11:66513200-66541200	Weak transcription	Aorta	Aorta
3	chr11:66513200-66555000	Weak transcription	Pancreas	Pancrea
4	chr11:66513400-66531600	Weak transcription	Rectal Smooth Muscle	rectum
5	chr11:66513400-66540800	Weak transcription	Spleen	Spleen
6	chr11:66513400-66547800	Weak transcription	Rectal Mucosa Donor 29	rectum
7	chr11:66513400-66606800	Weak transcription	Brain Angular Gyrus	brain
8	chr11:66513600-66530400	Weak transcription	Brain Inferior Temporal Lobe	brain
9	chr11:66513600-66532600	Weak transcription	Colonic Mucosa	Colon
10	chr11:66513600-66538800	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
11	chr11:66513800-66539800	Weak transcription	GM12878-XiMat	blood
12	chr11:66514400-66530400	Weak transcription	Primary B cells from cord blood	blood
13	chr11:66515400-66535800	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
14	chr11:66516600-66542200	Weak transcription	Muscle Satellite Cultured Cells	--
15	chr11:66516800-66535000	Weak transcription	HMEC	breast
16	chr11:66516800-66535200	Weak transcription	Fetal Brain Male	brain
17	chr11:66517400-66535200	Weak transcription	Osteobl	bone
18	chr11:66520800-66531000	Weak transcription	ES-I3 Cell Line	embryonic stem cell
19	chr11:66524000-66540600	Weak transcription	HUES6 Cell Line	embryonic stem cell
20	chr11:66524000-66542200	Weak transcription	Duodenum Smooth Muscle	Duodenum
21	chr11:66524200-66534000	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
22	chr11:66525400-66535000	Weak transcription	A549	lung
23	chr11:66525600-66538400	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
24	chr11:66526000-66530000	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
25	chr11:66526000-66531200	Weak transcription	Ovary	ovary
26	chr11:66526000-66533200	Strong transcription	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
27	chr11:66526400-66541400	Weak transcription	Small Intestine	intestine
28	chr11:66526600-66531200	Strong transcription	Primary B cells from peripheral blood	blood
29	chr11:66526600-66549800	Weak transcription	Lung	lung
30	chr11:66527000-66531400	Strong transcription	Fetal Intestine Small	intestine
31	chr11:66527000-66531600	Weak transcription	NHLF	lung
32	chr11:66527000-66532800	Strong transcription	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
33	chr11:66527000-66540200	Weak transcription	Primary T cells fromperipheralblood	blood
34	chr11:66527000-66574200	Weak transcription	Primary T helper cells fromperipheralblood	blood
35	chr11:66527000-66595600	Weak transcription	HSMM	muscle
36	chr11:66527200-66530200	Strong transcription	HUVEC	blood vessel
37	chr11:66527200-66531400	Strong transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
38	chr11:66527200-66531600	Strong transcription	Fetal Thymus	thymus
39	chr11:66527200-66532000	Strong transcription	HUES48 Cell Line	embryonic stem cell
40	chr11:66527200-66539600	Weak transcription	iPS-18 Cell Line	embryonic stem cell
41	chr11:66527400-66571600	Weak transcription	Primary T cells from cord blood	blood
42	chr11:66527600-66532000	Strong transcription	H9 Derived Neuron Cultured Cells	ES cell derived
43	chr11:66527600-66532200	Strong transcription	Fetal Stomach	stomach
44	chr11:66527600-66532400	Strong transcription	Thymus	Thymus
45	chr11:66527800-66531000	Strong transcription	iPS-20b Cell Line	embryonic stem cell
46	chr11:66527800-66539600	Weak transcription	Adipose Nuclei	Adipose
47	chr11:66528000-66530600	Strong transcription	IMR90 fetal lung fibroblasts Cell Line	lung
48	chr11:66528000-66534400	Strong transcription	HUES64 Cell Line	embryonic stem cell
49	chr11:66528200-66530800	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
50	chr11:66528200-66531000	Weak transcription	Colon Smooth Muscle	Colon

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links