Variant report

Variant	rs11635645
Chromosome Location	chr15:57394610-57394611
allele	A/C
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr15:57213938..57216093-chr15:57393779..57396458,2	MCF-7	breast:

Extended variants
information (count: 70 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:67)

rs_ID	r²[population]
rs10518894	0.96[ASN][1000 genomes]
rs10518895	0.90[ASN][1000 genomes]
rs11071305	0.85[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs11636100	0.98[ASN][1000 genomes]
rs11852340	0.97[ASN][1000 genomes]
rs11853331	0.86[ASN][1000 genomes]
rs11855648	0.93[ASN][1000 genomes]
rs12899904	0.92[ASN][1000 genomes]
rs12900038	0.92[ASN][1000 genomes]
rs12900589	0.93[AMR][1000 genomes];0.97[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs12900874	0.89[EUR][1000 genomes]
rs12909402	0.99[ASN][1000 genomes]
rs12910094	0.86[ASN][1000 genomes]
rs12910170	0.99[ASN][1000 genomes]
rs12912007	0.92[ASN][1000 genomes]
rs12914182	0.82[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs12914410	0.85[ASN][1000 genomes]
rs13313455	0.89[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs1820995	0.82[EUR][1000 genomes]
rs2169465	0.92[AMR][1000 genomes];0.95[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs2169466	0.81[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs2264904	0.88[AMR][1000 genomes];0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs2414494	0.82[ASN][1000 genomes]
rs2435907	0.82[EUR][1000 genomes]
rs2439918	0.83[EUR][1000 genomes]
rs2439919	0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2464429	0.83[EUR][1000 genomes]
rs2464430	0.83[EUR][1000 genomes]
rs2470079	0.80[EUR][1000 genomes]
rs2470082	0.82[EUR][1000 genomes]
rs2585088	0.82[EUR][1000 genomes]
rs2585112	0.83[EUR][1000 genomes]
rs2615231	0.89[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs2703576	0.84[EUR][1000 genomes]
rs2703577	0.84[EUR][1000 genomes]
rs2703580	0.84[EUR][1000 genomes]
rs2733170	0.80[EUR][1000 genomes]
rs2733177	0.83[EUR][1000 genomes]
rs2733182	0.82[EUR][1000 genomes]
rs2733185	0.83[EUR][1000 genomes]
rs2733188	0.84[AMR][1000 genomes];0.92[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs2733307	0.98[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs2733332	0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs28414972	0.91[AMR][1000 genomes];0.89[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs28514688	0.90[AMR][1000 genomes];0.89[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs28648502	0.90[AMR][1000 genomes];0.89[EUR][1000 genomes];0.89[ASN][1000 genomes]
rs2920265	0.82[EUR][1000 genomes]
rs2920267	0.83[EUR][1000 genomes]
rs2920269	0.85[EUR][1000 genomes]
rs2927189	0.85[AMR][1000 genomes];0.94[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs2951898	0.90[AMR][1000 genomes];0.94[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs2951899	0.90[AMR][1000 genomes];0.94[EUR][1000 genomes];0.83[ASN][1000 genomes]
rs2951901	0.82[EUR][1000 genomes]
rs2951903	0.85[EUR][1000 genomes]
rs2951904	0.83[EUR][1000 genomes]
rs2951906	0.82[EUR][1000 genomes]
rs2957574	0.82[EUR][1000 genomes]
rs2957591	0.89[AMR][1000 genomes];0.93[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs2962990	0.82[EUR][1000 genomes]
rs2962991	0.83[EUR][1000 genomes]
rs2962992	0.83[EUR][1000 genomes]
rs4774910	0.83[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs6493901	0.83[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7168387	0.90[AMR][1000 genomes];0.90[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs7173936	0.84[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs8037901	0.93[AMR][1000 genomes];0.94[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs967514	0.81[AMR][1000 genomes];0.89[EUR][1000 genomes];0.88[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:3 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1042486	chr15:57094598-57505992	Strong transcription Weak transcription Enhancers Flanking Active TSS Active TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent/Poised TSS Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA	21 gene(s)	inside rSNPs	diseases
2	nsv904251	chr15:57241970-57575916	Enhancers Weak transcription Strong transcription ZNF genes & repeats Flanking Active TSS Genic enhancers Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	8 gene(s)	inside rSNPs	diseases
3	nsv1045611	chr15:57350965-58070807	Weak transcription Enhancers Strong transcription Genic enhancers Flanking Active TSS Active TSS ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	49 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs11635645	TCF12	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:83 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr15:57324600-57398600	Weak transcription	Fetal Muscle Leg	muscle
2	chr15:57353800-57406400	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
3	chr15:57372600-57404000	Weak transcription	HSMMtube	muscle
4	chr15:57372600-57404200	Weak transcription	ES-I3 Cell Line	embryonic stem cell
5	chr15:57372800-57410200	Weak transcription	Muscle Satellite Cultured Cells	--
6	chr15:57374600-57398600	Weak transcription	Primary T helper cells PMA-I stimulated	--
7	chr15:57374800-57397800	Weak transcription	Primary hematopoietic stem cells short term culture	blood
8	chr15:57374800-57409600	Weak transcription	Osteobl	bone
9	chr15:57374800-57414600	Weak transcription	Fetal Kidney	kidney
10	chr15:57375000-57398000	Weak transcription	NH-A	brain
11	chr15:57375000-57398400	Weak transcription	Primary hematopoietic stem cells	blood
12	chr15:57376200-57406000	Weak transcription	Rectal Mucosa Donor 31	rectum
13	chr15:57376800-57397000	Weak transcription	Fetal Stomach	stomach
14	chr15:57380200-57401000	Strong transcription	Fetal Thymus	thymus
15	chr15:57381000-57412400	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
16	chr15:57381200-57404400	Weak transcription	Foreskin Keratinocyte Primary Cells skin02	Skin
17	chr15:57381200-57409400	Weak transcription	NHLF	lung
18	chr15:57381800-57403200	Weak transcription	H1 Cell Line	embryonic stem cell
19	chr15:57382400-57397200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
20	chr15:57382600-57403400	Weak transcription	Fetal Muscle Trunk	muscle
21	chr15:57382600-57403800	Weak transcription	Left Ventricle	heart
22	chr15:57382600-57423800	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
23	chr15:57382800-57404400	Weak transcription	Brain Inferior Temporal Lobe	brain
24	chr15:57382800-57404400	Weak transcription	Stomach Smooth Muscle	stomach
25	chr15:57382800-57419600	Weak transcription	K562	blood
26	chr15:57383000-57397800	Weak transcription	Ganglion Eminence derived primary cultured neurospheres	brain
27	chr15:57383000-57404000	Weak transcription	Foreskin Keratinocyte Primary Cells skin03	Skin
28	chr15:57383200-57403200	Weak transcription	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
29	chr15:57383800-57398200	Weak transcription	Cortex derived primary cultured neurospheres	brain
30	chr15:57384200-57409200	Weak transcription	Brain Germinal Matrix	brain
31	chr15:57384600-57401400	Weak transcription	Brain Angular Gyrus	brain
32	chr15:57384600-57404400	Weak transcription	Primary T helper naive cells fromperipheralblood	blood
33	chr15:57384600-57405600	Weak transcription	Brain Anterior Caudate	brain
34	chr15:57384600-57410400	Weak transcription	Primary T regulatory cells fromperipheralblood	blood
35	chr15:57385200-57406200	Weak transcription	HepG2	liver
36	chr15:57386200-57410200	Weak transcription	Ovary	ovary
37	chr15:57386400-57397600	Weak transcription	Fetal Lung	lung
38	chr15:57386400-57426600	Weak transcription	Primary T cells fromperipheralblood	blood
39	chr15:57386600-57399000	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
40	chr15:57386600-57404000	Weak transcription	HUES64 Cell Line	embryonic stem cell
41	chr15:57386600-57424600	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
42	chr15:57386800-57405600	Weak transcription	HUES48 Cell Line	embryonic stem cell
43	chr15:57387000-57396800	Weak transcription	Skeletal Muscle Female	skeletal muscle
44	chr15:57387000-57397800	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
45	chr15:57387000-57404400	Weak transcription	Duodenum Smooth Muscle	Duodenum
46	chr15:57387000-57406400	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
47	chr15:57387000-57430000	Weak transcription	Placenta	Placenta
48	chr15:57387200-57425400	Weak transcription	Primary T helper cells fromperipheralblood	blood
49	chr15:57387400-57398000	Weak transcription	Primary T cells from cord blood	blood
50	chr15:57387400-57399000	Weak transcription	Liver	Liver

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links