Variant report

Variant	rs1609525
Chromosome Location	chr3:157850447-157850448
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr3:157823071..157825253-chr3:157850410..157852335,2	K562	blood:
2	chr3:157849729..157851539-chr3:157855010..157858229,4	K562	blood:
3	chr3:157848788..157850916-chr3:157852376..157855126,2	MCF-7	breast:
4	chr3:157849729..157852576-chr3:157856575..157858121,2	K562	blood:

Variant related genes	Relation type
ENSG00000168779	Chromatin interaction
ENSG00000174891	Chromatin interaction

Extended variants
information (count: 146 )
Associated
traits (count: 2 )

rSNPs within LD-proxies of this variant (count:141)

rs_ID	r²[population]
rs10470472	0.86[EUR][1000 genomes]
rs1095633	0.82[CEU][hapmap]
rs1095636	0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs11706229	0.82[CEU][hapmap]
rs11717618	0.86[JPT][hapmap];0.89[YRI][hapmap]
rs11719153	0.82[YRI][hapmap]
rs1193511	1.00[CEU][hapmap];0.86[EUR][1000 genomes]
rs1193513	0.86[EUR][1000 genomes]
rs1193536	0.86[EUR][1000 genomes]
rs1204957	0.87[EUR][1000 genomes]
rs12485440	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12486461	1.00[AFR][1000 genomes];0.99[AMR][1000 genomes];1.00[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs12636733	0.88[YRI][hapmap]
rs12696067	1.00[CEU][hapmap];0.92[CHB][hapmap];0.93[JPT][hapmap];0.93[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs13059066	1.00[CEU][hapmap];0.86[JPT][hapmap];0.83[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs13061378	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];0.96[AMR][1000 genomes];0.99[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs13086348	0.82[CEU][hapmap]
rs1581408	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs1608100	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs1608101	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs1608968	0.82[CEU][hapmap]
rs1609526	0.92[AMR][1000 genomes];0.98[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs1610266	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs1610267	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs1610268	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs1624094	0.82[CEU][hapmap]
rs1724666	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs1724679	0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs1724727	0.82[CEU][hapmap]
rs1724728	0.82[CEU][hapmap]
rs1724729	0.82[CEU][hapmap]
rs1729997	0.82[CEU][hapmap]
rs1729998	1.00[CEU][hapmap];0.86[JPT][hapmap];0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs1730008	0.85[EUR][1000 genomes]
rs1730029	0.87[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs1730032	1.00[CEU][hapmap];0.86[JPT][hapmap];0.87[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs1730039	0.86[EUR][1000 genomes]
rs1730041	0.85[EUR][1000 genomes]
rs1730044	0.87[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs1730054	0.82[CEU][hapmap]
rs1730099	0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs1851062	0.84[JPT][hapmap]
rs1915935	1.00[CEU][hapmap];0.85[CHB][hapmap];0.85[JPT][hapmap];0.87[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs2682402	0.87[EUR][1000 genomes]
rs2682407	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs2693528	0.81[CEU][hapmap]
rs2693540	0.96[CEU][hapmap];0.87[EUR][1000 genomes]
rs2693546	1.00[CEU][hapmap];0.86[JPT][hapmap];0.88[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs4261830	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4261833	0.80[CEU][hapmap]
rs4317053	0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs4346508	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[YRI][hapmap];0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs4414801	0.97[AMR][1000 genomes];1.00[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs4431056	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];0.97[AMR][1000 genomes];0.98[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs4602343	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs4622858	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4642075	0.94[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs4680411	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4680412	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs4680413	0.99[ASN][1000 genomes]
rs4680421	0.85[JPT][hapmap]
rs57665991	0.99[ASN][1000 genomes]
rs6441174	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs6762706	0.83[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs6768496	0.82[CEU][hapmap]
rs6770442	0.89[AMR][1000 genomes];0.94[EUR][1000 genomes]
rs6773505	0.90[AMR][1000 genomes];0.99[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs6777853	0.82[CEU][hapmap]
rs6783175	0.87[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs6789448	1.00[AFR][1000 genomes];0.99[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs6790608	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];0.96[AMR][1000 genomes];0.99[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs6794461	0.97[AFR][1000 genomes];0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs6797626	0.95[AMR][1000 genomes];0.99[EUR][1000 genomes];0.92[ASN][1000 genomes]
rs6803532	0.93[AMR][1000 genomes];1.00[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs6803630	1.00[CEU][hapmap];1.00[CHB][hapmap];0.93[JPT][hapmap];0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];0.95[ASN][1000 genomes]
rs696715	1.00[CEU][hapmap];0.86[JPT][hapmap];0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs698975	1.00[CEU][hapmap];0.86[JPT][hapmap];0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs698976	1.00[CEU][hapmap];0.86[JPT][hapmap];0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs698977	0.88[EUR][1000 genomes]
rs698979	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs698981	1.00[CEU][hapmap];0.82[CHB][hapmap];0.86[JPT][hapmap];0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs698982	1.00[CEU][hapmap];0.86[JPT][hapmap];0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs698983	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs698984	0.86[EUR][1000 genomes]
rs698985	0.82[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs698992	1.00[CEU][hapmap];0.85[JPT][hapmap];0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs699918	1.00[CEU][hapmap];0.86[JPT][hapmap];0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs699923	0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs699925	0.82[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs699926	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs7614572	0.92[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.90[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7618071	0.83[EUR][1000 genomes]
rs7622971	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.90[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];0.96[EUR][1000 genomes];0.98[ASN][1000 genomes]
rs7623107	0.82[CEU][hapmap]
rs7624303	1.00[CHB][hapmap];1.00[JPT][hapmap];0.88[YRI][hapmap];0.99[ASN][1000 genomes]
rs7630176	1.00[CEU][hapmap];0.86[CHB][hapmap];1.00[JPT][hapmap];0.89[YRI][hapmap];0.97[AFR][1000 genomes];0.97[AMR][1000 genomes];0.99[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7642751	0.81[CEU][hapmap]
rs7645383	0.82[CEU][hapmap]
rs7645475	0.84[CEU][hapmap]
rs7647342	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.90[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7653039	0.90[EUR][1000 genomes]
rs827104	1.00[CEU][hapmap];0.85[JPT][hapmap];0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs827123	0.82[CEU][hapmap]
rs827130	1.00[CEU][hapmap];0.87[EUR][1000 genomes]
rs827139	1.00[CEU][hapmap];0.85[JPT][hapmap];0.87[EUR][1000 genomes]
rs827141	1.00[CEU][hapmap];0.85[JPT][hapmap];0.82[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs827142	1.00[CEU][hapmap];0.86[JPT][hapmap];0.82[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs827145	0.82[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs827146	0.82[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs827147	0.81[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs827149	0.83[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs827150	0.82[CEU][hapmap]
rs827153	1.00[CEU][hapmap];0.85[JPT][hapmap];0.84[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs827155	1.00[CEU][hapmap];0.86[JPT][hapmap];0.84[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs827157	0.84[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs827160	1.00[CEU][hapmap];0.86[JPT][hapmap];0.84[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs827162	1.00[CEU][hapmap];0.86[EUR][1000 genomes]
rs827168	1.00[CEU][hapmap];0.86[EUR][1000 genomes]
rs827170	1.00[CEU][hapmap];0.86[JPT][hapmap];0.81[AMR][1000 genomes];0.86[EUR][1000 genomes]
rs827173	1.00[CEU][hapmap];0.85[JPT][hapmap];0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs827174	0.81[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs827801	1.00[CEU][hapmap];0.86[JPT][hapmap];0.83[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs827805	1.00[CEU][hapmap];0.86[JPT][hapmap];0.83[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs844141	0.85[EUR][1000 genomes]
rs860422	0.89[EUR][1000 genomes]
rs862352	1.00[CEU][hapmap];0.86[JPT][hapmap];0.84[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs864331	0.96[CEU][hapmap];0.86[JPT][hapmap];0.83[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs864876	0.83[AMR][1000 genomes];0.93[EUR][1000 genomes]
rs866657	1.00[CEU][hapmap];0.86[JPT][hapmap];0.81[AMR][1000 genomes];0.88[EUR][1000 genomes]
rs9290020	0.95[AFR][1000 genomes];0.96[AMR][1000 genomes];0.97[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs9290021	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.86[AFR][1000 genomes];0.99[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs9811346	0.81[CEU][hapmap]
rs9814942	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.87[YRI][hapmap];1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs9820954	1.00[AFR][1000 genomes];1.00[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs9840667	0.82[CEU][hapmap]
rs9848433	0.97[AFR][1000 genomes];1.00[AMR][1000 genomes];0.98[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs9862337	0.81[AMR][1000 genomes];0.86[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs9870745	0.97[AMR][1000 genomes];0.95[EUR][1000 genomes];0.97[ASN][1000 genomes]
rs9871021	0.86[AMR][1000 genomes];0.93[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs9881063	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.89[YRI][hapmap];0.99[AMR][1000 genomes];1.00[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs9883891	0.82[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:5 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv1013391	chr3:157505943-158115553	Flanking Active TSS Bivalent/Poised TSS Weak transcription ZNF genes & repeats Enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Strong transcription Active TSS Genic enhancers Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	14 gene(s)	inside rSNPs	diseases
2	nsv536775	chr3:157505943-158115553	Enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Weak transcription Genic enhancers Bivalent Enhancer Strong transcription ZNF genes & repeats Flanking Active TSS Active TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA	14 gene(s)	inside rSNPs	diseases
3	nsv1002378	chr3:157715428-158673414	Flanking Active TSS Weak transcription Strong transcription Flanking Bivalent TSS/Enh Enhancers Bivalent Enhancer Bivalent/Poised TSS Active TSS Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	47 gene(s)	inside rSNPs	diseases
4	nsv829768	chr3:157832878-158012070	Weak transcription Strong transcription ZNF genes & repeats Enhancers Genic enhancers Flanking Active TSS Active TSS Bivalent Enhancer	TF binding region Chromatin interactive region lncRNA	3 gene(s)	inside rSNPs	diseases
5	esv8211	chr3:157850406-157850561	Weak transcription Strong transcription	Chromatin interactive region	2 gene(s)	inside rSNPs	n/a

mRNA abundance (count:2)

SNP	Gene	Cis/trans	Tissue	Source
rs1609525	RP11-538P18.2	cis	Artery Tibial	GTEx
rs1609525	RP11-538P18.2	cis	lung	GTEx

Chromatin state (count:101 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr3:157828600-157857000	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
2	chr3:157828800-157851000	Weak transcription	Right Ventricle	heart
3	chr3:157829200-157861400	Weak transcription	Rectal Smooth Muscle	rectum
4	chr3:157830000-157866400	Weak transcription	Primary T helper 17 cells PMA-I stimulated	--
5	chr3:157833200-157856200	Weak transcription	HUES48 Cell Line	embryonic stem cell
6	chr3:157836000-157851600	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
7	chr3:157836600-157854600	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
8	chr3:157837600-157877600	Weak transcription	Fetal Heart	heart
9	chr3:157838800-157862600	Weak transcription	Pancreas	Pancrea
10	chr3:157840200-157856000	Weak transcription	HUES6 Cell Line	embryonic stem cell
11	chr3:157840800-157856200	Strong transcription	Monocytes-CD14+_RO01746	blood
12	chr3:157842800-157851800	Weak transcription	Brain Germinal Matrix	brain
13	chr3:157842800-157855600	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
14	chr3:157842800-157855600	Weak transcription	Fetal Stomach	stomach
15	chr3:157842800-157855800	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
16	chr3:157842800-157856400	Weak transcription	Placenta	Placenta
17	chr3:157842800-157856800	Weak transcription	Skeletal Muscle Male	skeletal muscle
18	chr3:157842800-157858000	Weak transcription	Muscle Satellite Cultured Cells	--
19	chr3:157842800-157858200	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
20	chr3:157843000-157868600	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
21	chr3:157843400-157856600	Weak transcription	HUES64 Cell Line	embryonic stem cell
22	chr3:157843600-157857200	Weak transcription	HepG2	liver
23	chr3:157843600-157866200	Weak transcription	Primary T killer memory cells from peripheral blood	blood
24	chr3:157843600-157886800	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
25	chr3:157845800-157854200	Weak transcription	Primary T helper memory cells from peripheral blood 1	blood
26	chr3:157845800-157857600	Weak transcription	Primary T helper memory cells from peripheral blood 2	blood
27	chr3:157846000-157850600	Weak transcription	Brain Inferior Temporal Lobe	brain
28	chr3:157846000-157851600	Weak transcription	Fetal Kidney	kidney
29	chr3:157846000-157851800	Weak transcription	Fetal Brain Male	brain
30	chr3:157846000-157851800	Weak transcription	Osteobl	bone
31	chr3:157846000-157857400	Weak transcription	Spleen	Spleen
32	chr3:157846000-157860800	Weak transcription	Small Intestine	intestine
33	chr3:157846000-157868400	Weak transcription	Lung	lung
34	chr3:157846000-157869200	Weak transcription	Esophagus	oesophagus
35	chr3:157846200-157855800	Weak transcription	H9 Derived Neuron Cultured Cells	ES cell derived
36	chr3:157846200-157857200	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
37	chr3:157846200-157857200	Weak transcription	Brain Substantia Nigra	brain
38	chr3:157846200-157857400	Weak transcription	NHDF-Ad	bronchial
39	chr3:157846200-157857600	Weak transcription	Sigmoid Colon	Sigmoid Colon
40	chr3:157846200-157857800	Weak transcription	Fetal Muscle Trunk	muscle
41	chr3:157846200-157859200	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
42	chr3:157846200-157861800	Weak transcription	Colon Smooth Muscle	Colon
43	chr3:157846200-157862800	Weak transcription	Fetal Brain Female	brain
44	chr3:157846200-157869200	Weak transcription	Psoas Muscle	Psoas
45	chr3:157846200-157869200	Weak transcription	NHEK	skin
46	chr3:157846200-157872000	Weak transcription	Primary T cells from cord blood	blood
47	chr3:157846200-157875200	Weak transcription	Gastric	stomach
48	chr3:157846200-157893400	Weak transcription	Primary T helper naive cells fromperipheralblood	blood
49	chr3:157846200-157893600	Weak transcription	Aorta	Aorta
50	chr3:157846600-157855800	Weak transcription	Hela-S3	cervix

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