Variant report

Variant	rs2155219
Chromosome Location	chr11:76299194-76299195
allele	G/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr11:76299002-76300424	HUVEC	blood vessel:	n/a	n/a
2	FOS	chr11:76298896-76299200	MCF10A-Er-Src	breast:	n/a	n/a
3	CEBPB	chr11:76298727-76299240	IMR90	lung:	n/a	n/a
4	FOS	chr11:76298919-76299223	MCF10A-Er-Src	breast:	n/a	n/a
5	FOSL2	chr11:76298798-76299309	A549	lung:	n/a	n/a
6	FOS	chr11:76298897-76299228	MCF10A-Er-Src	breast:	n/a	n/a
7	FOS	chr11:76298923-76299224	MCF10A-Er-Src	breast:	n/a	n/a

Variant related genes	Relation type
ENSG00000254755	TF binding region

Extended variants
information (count: 13 )
Associated
traits (count: 7 )

rSNPs within LD-proxies of this variant (count:12)

rs_ID	r²[population]
rs10160518	0.83[AFR][1000 genomes];1.00[AMR][1000 genomes];0.99[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs11236791	0.83[EUR][1000 genomes]
rs11236795	0.94[ASN][1000 genomes]
rs11236797	0.83[EUR][1000 genomes]
rs4494327	0.92[AFR][1000 genomes];0.99[AMR][1000 genomes];0.96[EUR][1000 genomes];0.99[ASN][1000 genomes]
rs61893460	0.81[EUR][1000 genomes]
rs7110818	0.81[EUR][1000 genomes]
rs7114362	0.90[AMR][1000 genomes];0.85[EUR][1000 genomes]
rs7126418	0.81[EUR][1000 genomes]
rs7936312	0.86[EUR][1000 genomes]
rs7936323	0.85[AMR][1000 genomes];0.90[EUR][1000 genomes]
rs7936434	0.81[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv518717	chr11:76288937-76310976	Enhancers Weak transcription Flanking Active TSS Bivalent Enhancer Active TSS ZNF genes & repeats	TF binding region CpG island Chromatin interactive region	3 gene(s)	inside rSNPs	diseases

Variant related diseases (count:7)

Disease	PMID	Source
Ulcerative colitis	21297633	GWAS catalog
Allergic rhinitis	22036096	GWAS catalog
Allergic sensitization	23817571	GWAS catalog
IgE grass sensitization	22036096	GWAS catalog
Inflammatory bowel disease	23128233	GWAS catalog
Eosinophilic esophagitis	25017104	GWAS catalog
Self-reported allergy	23817569	GWAS catalog

Chromatin state (count:22 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr11:76291200-76299200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
2	chr11:76291600-76299800	Weak transcription	Lung	lung
3	chr11:76294800-76299600	Weak transcription	Stomach Smooth Muscle	stomach
4	chr11:76298200-76299400	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Male	--
5	chr11:76298200-76300800	Enhancers	Primary hematopoietic stem cells G-CSF-mobilized Female	--
6	chr11:76298200-76303200	Enhancers	Placenta	Placenta
7	chr11:76298200-76305000	Enhancers	Primary T regulatory cells fromperipheralblood	blood
8	chr11:76298400-76299200	Enhancers	Primary T helper 17 cells PMA-I stimulated	--
9	chr11:76298400-76299600	Enhancers	Primary T cells fromperipheralblood	blood
10	chr11:76298400-76301400	Enhancers	Primary hematopoietic stem cells short term culture	blood
11	chr11:76298600-76300000	Enhancers	Rectal Smooth Muscle	rectum
12	chr11:76298600-76300200	Enhancers	Primary B cells from cord blood	blood
13	chr11:76298600-76300200	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
14	chr11:76298600-76300400	Enhancers	Primary T helper cells fromperipheralblood	blood
15	chr11:76298600-76301000	Enhancers	HUVEC	blood vessel
16	chr11:76298800-76299200	Enhancers	Monocytes-CD14+_RO01746	blood
17	chr11:76298800-76299600	Enhancers	Foreskin Fibroblast Primary Cells skin01	Skin
18	chr11:76298800-76300200	Enhancers	Primary B cells from peripheral blood	blood
19	chr11:76298800-76300200	Enhancers	Primary T helper memory cells from peripheral blood 2	blood
20	chr11:76298800-76300200	Enhancers	Muscle Satellite Cultured Cells	--
21	chr11:76298800-76300400	Enhancers	Primary T cells effector/memory enriched fromperipheralblood	blood
22	chr11:76298800-76300800	Enhancers	Primary hematopoietic stem cells	blood

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