Variant report

Variant	rs5011832
Chromosome Location	chr10:21782842-21782843
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:21776929..21781312-chr10:21781870..21784606,5	K562	blood:
2	chr10:21781958..21784712-chr10:21823428..21825922,3	MCF-7	breast:
3	chr10:21462007..21464472-chr10:21781862..21786298,5	MCF-7	breast:
4	chr10:21777811..21781312-chr10:21782033..21784606,3	K562	blood:
5	chr10:21782529..21784336-chr10:21839315..21841955,2	MCF-7	breast:

Variant related genes	Relation type
ENSG00000078114	Chromatin interaction
ENSG00000231920	Chromatin interaction
ENSG00000078403	Chromatin interaction

Extended variants
information (count: 24 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:14)

rs_ID	r²[population]
rs10159545	0.90[EUR][1000 genomes]
rs10828246	0.83[AMR][1000 genomes];0.95[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs10828247	0.82[GIH][hapmap]
rs10828248	0.82[GIH][hapmap]
rs10828249	0.82[GIH][hapmap]
rs11012725	0.85[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs11012730	1.00[CHB][hapmap];0.90[GIH][hapmap];0.88[MEX][hapmap];0.86[TSI][hapmap];0.81[AMR][1000 genomes];0.84[EUR][1000 genomes]
rs11595807	0.84[LWK][hapmap];0.82[YRI][hapmap]
rs12256551	1.00[CHB][hapmap];0.83[EUR][1000 genomes]
rs12770228	0.81[AMR][1000 genomes];0.83[EUR][1000 genomes]
rs35106872	0.97[AFR][1000 genomes];0.97[AMR][1000 genomes];0.95[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs35336290	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes];0.98[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs874149	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[YRI][hapmap];0.95[AFR][1000 genomes];0.89[AMR][1000 genomes];0.96[EUR][1000 genomes];0.93[ASN][1000 genomes]
rs9732777	0.90[AMR][1000 genomes];0.96[EUR][1000 genomes];0.93[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:10 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv825284	chr10:21739527-21847437	Active TSS Weak transcription Flanking Active TSS Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Enhancers Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
2	nsv825285	chr10:21742026-21874334	Strong transcription Weak transcription Active TSS Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
3	nsv825286	chr10:21757784-21838890	Flanking Active TSS Bivalent/Poised TSS Weak transcription Active TSS Enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Genic enhancers Strong transcription Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
4	nsv825288	chr10:21759085-21831354	Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS Active TSS Enhancers Strong transcription Weak transcription Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
5	nsv825289	chr10:21762506-21845875	Strong transcription Enhancers Active TSS Bivalent/Poised TSS Flanking Active TSS Weak transcription Bivalent Enhancer Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
6	nsv527055	chr10:21764019-21822856	Bivalent/Poised TSS Weak transcription Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Active TSS Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3' Strong transcription ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
7	nsv825290	chr10:21777857-21830878	Active TSS Flanking Active TSS Weak transcription Flanking Bivalent TSS/Enh Bivalent Enhancer Strong transcription Bivalent/Poised TSS Enhancers Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
8	nsv894936	chr10:21781589-21827796	Active TSS Bivalent/Poised TSS Weak transcription Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Enhancers Genic enhancers Transcr. at gene 5' and 3' Strong transcription ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
9	nsv550200	chr10:21782842-21824727	Active TSS Bivalent/Poised TSS Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Weak transcription Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
10	nsv894937	chr10:21782842-21827796	Enhancers Transcr. at gene 5' and 3' Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Weak transcription Bivalent Enhancer Strong transcription Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs5011832	MLLT10	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:60 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:21778000-21783000	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
2	chr10:21778000-21783200	Weak transcription	HepG2	liver
3	chr10:21778200-21783000	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
4	chr10:21778200-21783400	Weak transcription	Muscle Satellite Cultured Cells	--
5	chr10:21778400-21783200	Weak transcription	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
6	chr10:21778400-21783200	Weak transcription	Cortex derived primary cultured neurospheres	brain
7	chr10:21780600-21783000	Weak transcription	Fetal Kidney	kidney
8	chr10:21781400-21783000	Enhancers	HUES48 Cell Line	embryonic stem cell
9	chr10:21781600-21783200	Enhancers	Placenta Amnion	Placenta Amnion
10	chr10:21781800-21783400	Weak transcription	NH-A	brain
11	chr10:21782200-21783000	Weak transcription	iPS-15b Cell Line	embryonic stem cell
12	chr10:21782600-21783000	Enhancers	Primary hematopoietic stem cells short term culture	blood
13	chr10:21782600-21783400	Flanking Active TSS	Primary hematopoietic stem cells G-CSF-mobilized Male	--
14	chr10:21782600-21786400	Active TSS	ES-I3 Cell Line	embryonic stem cell
15	chr10:21782800-21783000	Flanking Active TSS	H1 Cell Line	embryonic stem cell
16	chr10:21782800-21783000	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
17	chr10:21782800-21783000	Enhancers	HUES6 Cell Line	embryonic stem cell
18	chr10:21782800-21783000	Active TSS	HUES64 Cell Line	embryonic stem cell
19	chr10:21782800-21783000	Enhancers	iPS-18 Cell Line	embryonic stem cell
20	chr10:21782800-21783000	Bivalent Enhancer	iPS-20b Cell Line	embryonic stem cell
21	chr10:21782800-21783000	Flanking Active TSS	ES-UCSF4 Cell Line	embryonic stem cell
22	chr10:21782800-21783000	Bivalent Enhancer	Primary monocytes fromperipheralblood	blood
23	chr10:21782800-21783000	Bivalent Enhancer	Primary B cells from cord blood	blood
24	chr10:21782800-21783000	Bivalent Enhancer	Primary B cells from peripheral blood	blood
25	chr10:21782800-21783000	Bivalent Enhancer	Primary T killer naive cells fromperipheralblood	blood
26	chr10:21782800-21783000	Enhancers	Foreskin Fibroblast Primary Cells skin01	Skin
27	chr10:21782800-21783000	Enhancers	Foreskin Keratinocyte Primary Cells skin02	Skin
28	chr10:21782800-21783000	Enhancers	Adipose Nuclei	Adipose
29	chr10:21782800-21783000	Active TSS	Liver	Liver
30	chr10:21782800-21783000	Enhancers	Brain Anterior Caudate	brain
31	chr10:21782800-21783000	Enhancers	Brain Hippocampus Middle	brain
32	chr10:21782800-21783000	Bivalent/Poised TSS	Colonic Mucosa	Colon
33	chr10:21782800-21783000	Enhancers	Fetal Heart	heart
34	chr10:21782800-21783000	Enhancers	Fetal Muscle Leg	muscle
35	chr10:21782800-21783000	Bivalent Enhancer	GM12878-XiMat	blood
36	chr10:21782800-21783000	Bivalent Enhancer	Monocytes-CD14+_RO01746	blood
37	chr10:21782800-21783000	Enhancers	NHEK	skin
38	chr10:21782800-21783200	Enhancers	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
39	chr10:21782800-21783200	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
40	chr10:21782800-21783200	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
41	chr10:21782800-21783200	Enhancers	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
42	chr10:21782800-21783200	Flanking Active TSS	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
43	chr10:21782800-21783200	Enhancers	iPS DF 6.9 Cell Line	embryonic stem cell
44	chr10:21782800-21783200	Enhancers	iPS DF 19.11 Cell Line	embryonic stem cell
45	chr10:21782800-21783200	Bivalent Enhancer	Primary T helper naive cells fromperipheralblood	blood
46	chr10:21782800-21783200	Bivalent Enhancer	Primary T helper cells PMA-I stimulated	--
47	chr10:21782800-21783200	Bivalent Enhancer	Primary T helper cells fromperipheralblood	blood
48	chr10:21782800-21783200	Enhancers	Esophagus	oesophagus
49	chr10:21782800-21783200	Flanking Active TSS	Fetal Lung	lung
50	chr10:21782800-21783200	Enhancers	Fetal Muscle Trunk	muscle

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links