Variant report

Variant	rs11012725
Chromosome Location	chr10:21793824-21793825
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr10:21793185..21794844-chr10:21800721..21802382,2	K562	blood:
2	chr10:21793503..21796210-chr10:21823164..21825409,2	MCF-7	breast:
3	chr10:21792418..21794145-chr10:21895040..21897901,2	K562	blood:
4	chr10:21793213..21796625-chr10:21800997..21804362,3	MCF-7	breast:

Variant related genes	Relation type
ENSG00000078403	Chromatin interaction

Extended variants
information (count: 24 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:10)

rs_ID	r²[population]
rs10159545	0.83[AMR][1000 genomes];0.89[EUR][1000 genomes]
rs10828246	0.87[AMR][1000 genomes];0.91[EUR][1000 genomes]
rs11012730	0.87[AFR][1000 genomes];0.96[AMR][1000 genomes];0.90[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs12256551	0.92[AMR][1000 genomes];0.91[EUR][1000 genomes];0.96[ASN][1000 genomes]
rs35106872	0.82[AMR][1000 genomes];0.87[EUR][1000 genomes]
rs35336290	0.85[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs5011832	0.85[AMR][1000 genomes];0.92[EUR][1000 genomes]
rs874149	0.90[EUR][1000 genomes]
rs946711	0.80[AMR][1000 genomes]
rs9732777	0.89[AMR][1000 genomes];0.92[EUR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:14 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv825284	chr10:21739527-21847437	Active TSS Weak transcription Flanking Active TSS Flanking Bivalent TSS/Enh Strong transcription Bivalent/Poised TSS Enhancers Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
2	nsv825285	chr10:21742026-21874334	Strong transcription Weak transcription Active TSS Flanking Bivalent TSS/Enh Flanking Active TSS Bivalent/Poised TSS Enhancers Bivalent Enhancer Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
3	nsv825286	chr10:21757784-21838890	Flanking Active TSS Bivalent/Poised TSS Weak transcription Active TSS Enhancers Flanking Bivalent TSS/Enh Bivalent Enhancer Genic enhancers Strong transcription Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
4	nsv825288	chr10:21759085-21831354	Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS Active TSS Enhancers Strong transcription Weak transcription Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
5	nsv825289	chr10:21762506-21845875	Strong transcription Enhancers Active TSS Bivalent/Poised TSS Flanking Active TSS Weak transcription Bivalent Enhancer Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
6	nsv527055	chr10:21764019-21822856	Bivalent/Poised TSS Weak transcription Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Active TSS Bivalent Enhancer Genic enhancers Transcr. at gene 5' and 3' Strong transcription ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	34 gene(s)	inside rSNPs	diseases
7	nsv825290	chr10:21777857-21830878	Active TSS Flanking Active TSS Weak transcription Flanking Bivalent TSS/Enh Bivalent Enhancer Strong transcription Bivalent/Poised TSS Enhancers Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
8	nsv894936	chr10:21781589-21827796	Active TSS Bivalent/Poised TSS Weak transcription Flanking Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh Enhancers Genic enhancers Transcr. at gene 5' and 3' Strong transcription ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
9	nsv550200	chr10:21782842-21824727	Active TSS Bivalent/Poised TSS Enhancers Flanking Active TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Weak transcription Strong transcription ZNF genes & repeats Transcr. at gene 5' and 3' Genic enhancers	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
10	nsv894937	chr10:21782842-21827796	Enhancers Transcr. at gene 5' and 3' Flanking Active TSS Active TSS Flanking Bivalent TSS/Enh Bivalent/Poised TSS Weak transcription Bivalent Enhancer Strong transcription Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
11	nsv517469	chr10:21783634-21822856	Active TSS Bivalent Enhancer Flanking Active TSS Weak transcription Enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
12	nsv894938	chr10:21784899-21827796	Enhancers Flanking Active TSS Active TSS Weak transcription Bivalent/Poised TSS Flanking Bivalent TSS/Enh Bivalent Enhancer Strong transcription Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA	33 gene(s)	inside rSNPs	diseases
13	nsv894939	chr10:21789406-21830104	Bivalent Enhancer Enhancers Active TSS Flanking Active TSS Bivalent/Poised TSS Weak transcription Flanking Bivalent TSS/Enh Strong transcription Transcr. at gene 5' and 3' Genic enhancers ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases
14	nsv825291	chr10:21792100-21830946	Active TSS Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Weak transcription Strong transcription Bivalent Enhancer Bivalent/Poised TSS Genic enhancers Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs11012725	MLLT10	Cis_1M	lymphoblastoid	RTeQTL

Chromatin state (count:29 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:21786600-21795000	Weak transcription	K562	blood
2	chr10:21788400-21794600	Weak transcription	A549	lung
3	chr10:21789200-21794600	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
4	chr10:21789200-21794800	Enhancers	hESC Derived CD184+ Endoderm Cultured Cells	ES cell derived
5	chr10:21789600-21794400	Enhancers	HepG2	liver
6	chr10:21789600-21794600	Enhancers	Liver	Liver
7	chr10:21789800-21794800	Weak transcription	Right Atrium	heart
8	chr10:21789800-21799800	Weak transcription	Lung	lung
9	chr10:21790200-21794600	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
10	chr10:21790200-21795200	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
11	chr10:21790200-21795600	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
12	chr10:21790200-21797800	Weak transcription	Placenta Amnion	Placenta Amnion
13	chr10:21790400-21795200	Weak transcription	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
14	chr10:21790400-21795600	Weak transcription	Fetal Lung	lung
15	chr10:21790400-21797600	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
16	chr10:21790600-21794600	Bivalent Enhancer	iPS-15b Cell Line	embryonic stem cell
17	chr10:21790600-21794800	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
18	chr10:21790600-21794800	Weak transcription	Fetal Muscle Leg	muscle
19	chr10:21790600-21795200	Enhancers	H9 Derived Neuron Cultured Cells	ES cell derived
20	chr10:21791400-21794600	Enhancers	HUES64 Cell Line	embryonic stem cell
21	chr10:21791600-21795600	Weak transcription	Placenta	Placenta
22	chr10:21791800-21794000	Weak transcription	Fetal Heart	heart
23	chr10:21791800-21794800	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
24	chr10:21793200-21794600	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
25	chr10:21793200-21794800	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
26	chr10:21793400-21794400	Weak transcription	iPS-20b Cell Line	embryonic stem cell
27	chr10:21793400-21794600	Weak transcription	Fetal Kidney	kidney
28	chr10:21793800-21794200	Bivalent Enhancer	HUES6 Cell Line	embryonic stem cell
29	chr10:21793800-21794800	Bivalent Enhancer	iPS-18 Cell Line	embryonic stem cell

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