Variant report

Variant	rs6459157
Chromosome Location	chr6:56229158-56229159
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type
1	chr6:56225017..56229279-chr6:56229711..56233671,3	MCF-7	breast:
2	chr6:56227775..56231675-chr6:56232771..56236094,3	K562	blood:
3	chr6:56226560..56229284-chr6:56234863..56237293,2	MCF-7	breast:

Extended variants
information (count: 23 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:22)

rs_ID	r²[population]
rs11751569	0.93[CHB][hapmap]
rs11757910	0.87[CHB][hapmap]
rs11757941	0.87[CHB][hapmap]
rs12110833	0.87[CHB][hapmap]
rs13218268	0.87[CHB][hapmap]
rs13220153	0.87[CHB][hapmap]
rs16887812	0.87[CHB][hapmap]
rs2206531	0.83[CHB][hapmap]
rs2206533	0.81[CHB][hapmap]
rs2294697	0.87[CHB][hapmap]
rs4140500	0.98[ASN][1000 genomes]
rs4715616	0.83[CHB][hapmap]
rs4715617	0.83[CHB][hapmap]
rs7764788	1.00[CHB][hapmap];0.89[JPT][hapmap];0.90[ASN][1000 genomes]
rs7770594	1.00[CHB][hapmap];0.95[JPT][hapmap];0.98[ASN][1000 genomes]
rs9296842	0.83[CHB][hapmap]
rs9370525	0.88[CHB][hapmap];0.84[CHD][hapmap];0.91[ASN][1000 genomes]
rs9382623	0.83[CHB][hapmap]
rs9382624	0.88[CHB][hapmap];0.84[JPT][hapmap];0.86[ASN][1000 genomes]
rs9464383	1.00[CHB][hapmap];0.94[JPT][hapmap];0.98[ASN][1000 genomes]
rs994376	0.83[CHB][hapmap]
rs999231	0.98[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv491933	chr6:56177722-57171010	Active TSS Enhancers Strong transcription Weak transcription Genic enhancers Flanking Active TSS ZNF genes & repeats Flanking Bivalent TSS/Enh Bivalent/Poised TSS Bivalent Enhancer Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	51 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs6459157	GCLC	cis	parietal	SCAN

Chromatin state (count:37 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr6:56218400-56229200	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
2	chr6:56221400-56231000	Weak transcription	Right Ventricle	heart
3	chr6:56221600-56233200	Weak transcription	NHLF	lung
4	chr6:56221800-56229800	Weak transcription	Fetal Stomach	stomach
5	chr6:56222400-56231000	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
6	chr6:56222600-56229200	Weak transcription	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
7	chr6:56222600-56230800	Weak transcription	Fetal Heart	heart
8	chr6:56222600-56231000	Weak transcription	Stomach Smooth Muscle	stomach
9	chr6:56222800-56229200	Weak transcription	IMR90 fetal lung fibroblasts Cell Line	lung
10	chr6:56223000-56229200	Weak transcription	NHDF-Ad	bronchial
11	chr6:56223400-56229200	Weak transcription	Colon Smooth Muscle	Colon
12	chr6:56223400-56231000	Weak transcription	Fetal Lung	lung
13	chr6:56224200-56229200	Weak transcription	NHEK	skin
14	chr6:56224400-56230800	Weak transcription	Fetal Kidney	kidney
15	chr6:56224600-56231000	Weak transcription	Adipose Nuclei	Adipose
16	chr6:56225200-56234800	Weak transcription	Brain Hippocampus Middle	brain
17	chr6:56225200-56235200	Weak transcription	Brain Cingulate Gyrus	brain
18	chr6:56225200-56235200	Weak transcription	Brain Inferior Temporal Lobe	brain
19	chr6:56225800-56233200	Enhancers	HUVEC	blood vessel
20	chr6:56226600-56229600	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
21	chr6:56227200-56234800	Enhancers	Hela-S3	cervix
22	chr6:56227800-56229400	Enhancers	HepG2	liver
23	chr6:56228400-56230400	Enhancers	Pancreatic Islets	Pancreatic Islet
24	chr6:56228600-56229400	Enhancers	Brain Anterior Caudate	brain
25	chr6:56228600-56230200	Enhancers	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
26	chr6:56228600-56232400	Enhancers	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
27	chr6:56228600-56232800	Enhancers	Breast Myoepithelial Primary Cells	Breast
28	chr6:56228800-56229400	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
29	chr6:56228800-56230000	Enhancers	HSMMtube	muscle
30	chr6:56228800-56230800	Enhancers	Osteobl	bone
31	chr6:56228800-56231200	Enhancers	HMEC	breast
32	chr6:56229000-56229200	Enhancers	Left Ventricle	heart
33	chr6:56229000-56230000	Enhancers	Mesenchymal Stem Cell Derived Chondrocyte Cultured Cells	embryonic stem cell
34	chr6:56229000-56230000	Enhancers	Rectal Smooth Muscle	rectum
35	chr6:56229000-56230200	Enhancers	HSMM	muscle
36	chr6:56229000-56230600	Enhancers	NH-A	brain
37	chr6:56229000-56231000	Weak transcription	Fetal Muscle Leg	muscle

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