Variant report

Variant	rs7006428
Chromosome Location	chr8:121621426-121621427
allele	A/G
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Distal block	Cell Line	Cell type	Cell Stage
1	chr8:121619967..121621577-chr8:121621884..121624584,2	MCF-7	breast:

Extended variants
information (count: 9 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:7)

rs_ID	r²[population]
rs10094047	1.00[CHD][hapmap]
rs11776321	1.00[ASN][1000 genomes]
rs4870734	0.92[MKK][hapmap];0.90[TSI][hapmap];0.81[YRI][hapmap]
rs4871071	0.85[CEU][hapmap];0.84[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs6989609	1.00[ASN][1000 genomes]
rs6990426	1.00[ASN][1000 genomes]
rs7824721	1.00[ASN][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:2 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv891421	chr8:121292407-121653902	Weak transcription ZNF genes & repeats Strong transcription Enhancers Flanking Active TSS Genic enhancers Active TSS Transcr. at gene 5' and 3' Bivalent/Poised TSS Bivalent Enhancer	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	8 gene(s)	inside rSNPs	diseases
2	nsv612113	chr8:121616345-121635396	Enhancers Weak transcription Strong transcription Genic enhancers ZNF genes & repeats Flanking Active TSS	Chromatin interactive region	3 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs7006428	SOCS2	trans	lymphoblastoid	seeQTL

Chromatin state (count:44 , 50 per page) page: 1

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr8:121587200-121623000	Weak transcription	Fetal Intestine Small	intestine
2	chr8:121587800-121640600	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
3	chr8:121588200-121642400	Weak transcription	Primary T cells fromperipheralblood	blood
4	chr8:121588600-121636600	Weak transcription	Primary B cells from cord blood	blood
5	chr8:121601200-121623200	Weak transcription	Primary T helper cells PMA-I stimulated	--
6	chr8:121602000-121627600	Weak transcription	Aorta	Aorta
7	chr8:121603200-121626400	Weak transcription	Fetal Adrenal Gland	Adrenal Gland
8	chr8:121605800-121644400	Weak transcription	Gastric	stomach
9	chr8:121606200-121626200	Weak transcription	HSMMtube	muscle
10	chr8:121607400-121623200	Weak transcription	Primary T helper naive cells fromperipheralblood	blood
11	chr8:121607600-121643000	Weak transcription	Fetal Intestine Large	intestine
12	chr8:121609600-121641000	Weak transcription	Lung	lung
13	chr8:121609800-121629000	Weak transcription	Fetal Muscle Leg	muscle
14	chr8:121609800-121629000	Weak transcription	Fetal Stomach	stomach
15	chr8:121610200-121623000	Weak transcription	Primary Natural Killer cells fromperipheralblood	blood
16	chr8:121610400-121627400	Weak transcription	Cortex derived primary cultured neurospheres	brain
17	chr8:121610800-121629800	Weak transcription	Primary hematopoietic stem cells	blood
18	chr8:121611400-121624400	Weak transcription	Primary T helper cells fromperipheralblood	blood
19	chr8:121613200-121621600	Weak transcription	Spleen	Spleen
20	chr8:121613200-121622800	Weak transcription	Primary monocytes fromperipheralblood	blood
21	chr8:121613200-121623000	Weak transcription	Primary hematopoietic stem cells G-CSF-mobilized Male	--
22	chr8:121613200-121668000	Weak transcription	Pancreas	Pancrea
23	chr8:121613400-121637200	Weak transcription	Bone Marrow Derived Cultured Mesenchymal Stem Cells	Bone marrow
24	chr8:121614800-121627600	Weak transcription	Foreskin Fibroblast Primary Cells skin02	Skin
25	chr8:121615400-121624400	Strong transcription	Monocytes-CD14+_RO01746	blood
26	chr8:121616000-121637200	Weak transcription	HSMM	muscle
27	chr8:121616600-121621600	Weak transcription	Liver	Liver
28	chr8:121616600-121639000	Weak transcription	Primary hematopoietic stem cells short term culture	blood
29	chr8:121616800-121624400	Weak transcription	Primary T killer naive cells fromperipheralblood	blood
30	chr8:121618000-121626000	Weak transcription	Osteobl	bone
31	chr8:121618000-121629000	Weak transcription	Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	ES cell derived
32	chr8:121618200-121626600	Weak transcription	NHLF	lung
33	chr8:121618200-121634000	Weak transcription	Foreskin Fibroblast Primary Cells skin01	Skin
34	chr8:121618400-121637200	Weak transcription	H1 Derived Mesenchymal Stem Cells	ES cell derived
35	chr8:121618800-121624600	Strong transcription	HepG2	liver
36	chr8:121619000-121633400	Weak transcription	Adipose Derived Mesenchymal Stem Cell Cultured Cells	ES cell derived
37	chr8:121619800-121621600	Strong transcription	Primary hematopoietic stem cells G-CSF-mobilized Female	--
38	chr8:121620200-121623000	Weak transcription	H1 Cell Line	embryonic stem cell
39	chr8:121620600-121623600	Weak transcription	Primary T cells from cord blood	blood
40	chr8:121621200-121622200	Enhancers	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
41	chr8:121621400-121621600	Enhancers	iPS-18 Cell Line	embryonic stem cell
42	chr8:121621400-121622000	Enhancers	iPS-20b Cell Line	embryonic stem cell
43	chr8:121621400-121622200	Enhancers	ES-I3 Cell Line	embryonic stem cell
44	chr8:121621400-121622200	Enhancers	ES-UCSF4 Cell Line	embryonic stem cell

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links