Variant report

Variant	rs7094916
Chromosome Location	chr10:1037091-1037092
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

TF binding
region (count:19)
CpG islands
(count:0)
Chromatin interactive
region (count:7)
LncRNA
region (count:0)
Mature miRNA
region (count: 0)
miRNA target
sites (count:0)

(count:19 , 50 per page) page: 1

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr10:1036744-1037182	K562	blood:	n/a	n/a
2	POLR2A	chr10:1036579-1037247	GM12878	blood:	n/a	n/a
3	POLR2A	chr10:1036560-1037467	GM12878	blood:	n/a	n/a
4	POLR2A	chr10:1036687-1037311	GM12892	blood:	n/a	n/a
5	POLR2A	chr10:1036590-1037241	GM12892	blood:	n/a	n/a
6	POLR2A	chr10:1036708-1037193	H1-hESC	embryonic stem cell:	n/a	n/a
7	POLR2A	chr10:1036562-1037332	GM12892	blood:	n/a	n/a
8	POLR2A	chr10:1036743-1037226	H1-hESC	embryonic stem cell:	n/a	n/a
9	POLR2A	chr10:1036687-1037101	H1-hESC	embryonic stem cell:	n/a	n/a
10	TAL1	chr10:1036582-1037130	K562	blood:	n/a	n/a
11	POLR2A	chr10:1036784-1037236	PFSK-1	brain:	n/a	n/a
12	WRNIP1	chr10:1036756-1037200	GM12878	blood:	n/a	n/a
13	HEY1	chr10:1036677-1037243	K562	blood:	n/a	n/a
14	POLR2A	chr10:1036724-1037307	HepG2	liver:	n/a	n/a
15	POLR2A	chr10:1036669-1037228	GM12892	blood:	n/a	n/a
16	POLR2A	chr10:1036673-1037198	GM12891	blood:	n/a	n/a
17	POLR2A	chr10:1036810-1037098	GM12878	blood:	n/a	n/a
18	POLR2A	chr10:1036682-1037354	A549	lung:	n/a	n/a
19	POLR2A	chr10:1036698-1037322	H1-hESC	embryonic stem cell:	n/a	n/a

No data

(count:7 , 50 per page) page: 1

No.	Distal block	Cell Line	Cell type
1	chr10:1033990..1039615-chr10:1093691..1098446,7	MCF-7	breast:
2	chr10:1032460..1036223-chr10:1037053..1039174,5	K562	blood:
3	chr10:993403..996250-chr10:1036309..1038565,2	K562	blood:
4	chr10:1036759..1038739-chr10:1058886..1061197,2	MCF-7	breast:
5	chr10:974439..980732-chr10:1030011..1038533,28	MCF-7	breast:
6	chr10:1003784..1006528-chr10:1035596..1037131,2	K562	blood:
7	chr10:974510..978091-chr10:1036448..1040062,6	K562	blood:

No data

Variant related genes	Relation type
ENSG00000205740	TF binding region
ENSG00000107929	Chromatin interaction
ENSG00000067064	Chromatin interaction
ENSG00000107937	Chromatin interaction
ENSG00000047056	Chromatin interaction
ENSG00000205740	Chromatin interaction
ENSG00000229869	Chromatin interaction

Extended variants
information (count: 69 )
Associated
traits (count: 1 )

rSNPs within LD-proxies of this variant (count:47)

rs_ID	r²[population]
rs10795304	1.00[CEU][hapmap];1.00[CHB][hapmap];0.92[JPT][hapmap];0.83[AMR][1000 genomes];0.92[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs10795305	0.94[CEU][hapmap];0.80[CHB][hapmap];0.94[CHD][hapmap];0.97[GIH][hapmap];0.94[JPT][hapmap];1.00[MEX][hapmap];0.86[TSI][hapmap];0.85[AMR][1000 genomes];0.92[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs10795307	0.86[AMR][1000 genomes];0.92[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs10903355	0.84[CEU][hapmap]
rs10903357	0.84[CEU][hapmap]
rs10904592	0.83[AMR][1000 genomes];0.93[EUR][1000 genomes];0.81[ASN][1000 genomes]
rs10904593	1.00[ASW][hapmap];0.94[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];0.94[GIH][hapmap];0.94[JPT][hapmap];0.90[LWK][hapmap];0.95[MEX][hapmap];0.87[MKK][hapmap];0.86[TSI][hapmap];0.81[AFR][1000 genomes];0.89[AMR][1000 genomes];0.92[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs11250239	0.81[CEU][hapmap]
rs11253516	0.94[CEU][hapmap]
rs11253526	0.88[CEU][hapmap]
rs11253527	0.94[CEU][hapmap]
rs11253542	1.00[ASW][hapmap];0.94[CEU][hapmap];1.00[CHB][hapmap];1.00[CHD][hapmap];0.94[GIH][hapmap];0.94[JPT][hapmap];0.95[LWK][hapmap];1.00[MEX][hapmap];0.93[MKK][hapmap];0.86[TSI][hapmap];1.00[YRI][hapmap];0.97[AFR][1000 genomes];0.90[AMR][1000 genomes];0.92[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs11253543	0.94[CEU][hapmap];0.80[CHB][hapmap];0.91[CHD][hapmap];0.97[GIH][hapmap];0.94[JPT][hapmap];1.00[MEX][hapmap];0.86[TSI][hapmap];0.85[AMR][1000 genomes];0.92[EUR][1000 genomes];0.82[ASN][1000 genomes]
rs11253544	0.83[AMR][1000 genomes];0.86[ASN][1000 genomes]
rs11253564	1.00[CEU][hapmap];0.90[CHB][hapmap];0.88[JPT][hapmap];0.92[AMR][1000 genomes];0.96[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs11599792	0.89[JPT][hapmap]
rs12217202	0.92[AMR][1000 genomes];0.96[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs12268008	0.89[JPT][hapmap]
rs12355506	0.90[EUR][1000 genomes]
rs12415759	0.81[JPT][hapmap]
rs2170142	1.00[CEU][hapmap];1.00[CHB][hapmap];0.94[JPT][hapmap]
rs2279257	1.00[CEU][hapmap];0.95[CHB][hapmap]
rs2306404	1.00[CEU][hapmap];1.00[CHB][hapmap];0.97[CHD][hapmap];1.00[GIH][hapmap];0.94[JPT][hapmap];1.00[MEX][hapmap];0.96[TSI][hapmap]
rs2306406	1.00[CEU][hapmap];1.00[CHB][hapmap];0.97[CHD][hapmap];1.00[GIH][hapmap];0.94[JPT][hapmap];1.00[MEX][hapmap];0.96[TSI][hapmap]
rs2306408	1.00[CEU][hapmap];0.90[CHB][hapmap];1.00[CHD][hapmap];1.00[GIH][hapmap];0.94[JPT][hapmap];0.83[MEX][hapmap];0.96[TSI][hapmap];0.83[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs2306409	0.84[JPT][hapmap]
rs2892252	0.88[CEU][hapmap];0.97[AFR][1000 genomes];0.92[AMR][1000 genomes];0.92[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs2892253	0.96[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs3765102	1.00[CEU][hapmap];1.00[CHB][hapmap];0.89[AMR][1000 genomes];0.97[EUR][1000 genomes];0.88[ASN][1000 genomes]
rs4880745	0.89[JPT][hapmap]
rs4881547	0.88[JPT][hapmap]
rs5027030	0.97[AFR][1000 genomes];0.92[AMR][1000 genomes];0.92[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs6560861	0.83[CEU][hapmap]
rs7069123	0.89[JPT][hapmap]
rs7071250	1.00[CEU][hapmap];1.00[CHB][hapmap];1.00[JPT][hapmap];0.94[AMR][1000 genomes];0.98[EUR][1000 genomes];0.94[ASN][1000 genomes]
rs7075695	0.84[CEU][hapmap]
rs7081516	0.94[AMR][1000 genomes];0.98[EUR][1000 genomes];1.00[ASN][1000 genomes]
rs7082783	0.92[AMR][1000 genomes];0.96[EUR][1000 genomes];0.90[ASN][1000 genomes]
rs7093767	0.94[CEU][hapmap]
rs7097976	0.94[CEU][hapmap];0.80[CHB][hapmap];0.94[JPT][hapmap];0.86[AMR][1000 genomes];0.92[EUR][1000 genomes];0.87[ASN][1000 genomes]
rs7101191	0.84[CEU][hapmap]
rs7900801	0.84[JPT][hapmap]
rs7905827	0.92[EUR][1000 genomes];0.85[ASN][1000 genomes]
rs7915650	0.89[CEU][hapmap]
rs7917055	0.94[CEU][hapmap];0.90[CHB][hapmap];0.88[JPT][hapmap];0.92[AMR][1000 genomes];0.96[EUR][1000 genomes];0.91[ASN][1000 genomes]
rs7920922	0.86[AMR][1000 genomes];0.92[EUR][1000 genomes];0.86[ASN][1000 genomes]
rs947403	0.89[JPT][hapmap]

Variant overlapped rSNPs/rCNVs (count:22 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv916591	chr10:224406-1088734	Enhancers Weak transcription Strong transcription Active TSS Bivalent Enhancer ZNF genes & repeats Flanking Active TSS Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	38 gene(s)	inside rSNPs	diseases
2	nsv540386	chr10:224406-1197416	Active TSS Weak transcription Enhancers Strong transcription Flanking Active TSS ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	51 gene(s)	inside rSNPs	diseases
3	nsv1054659	chr10:611444-1133578	Weak transcription Enhancers Flanking Active TSS Bivalent Enhancer Strong transcription Genic enhancers Active TSS ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA	43 gene(s)	inside rSNPs	diseases
4	nsv466697	chr10:734229-1129527	ZNF genes & repeats Weak transcription Flanking Active TSS Strong transcription Active TSS Bivalent Enhancer Enhancers Genic enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
5	nsv549765	chr10:734229-1129527	Genic enhancers Enhancers Active TSS Flanking Active TSS ZNF genes & repeats Weak transcription Strong transcription Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	39 gene(s)	inside rSNPs	diseases
6	nsv530116	chr10:776548-1401075	Weak transcription Enhancers Strong transcription Genic enhancers Flanking Active TSS Active TSS ZNF genes & repeats Bivalent Enhancer Bivalent/Poised TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	41 gene(s)	inside rSNPs	diseases
7	nsv1052540	chr10:887562-1300134	Strong transcription Weak transcription Enhancers Active TSS Genic enhancers ZNF genes & repeats Flanking Active TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
8	nsv540407	chr10:887562-1300134	Weak transcription Enhancers Active TSS Strong transcription Flanking Active TSS Genic enhancers ZNF genes & repeats Transcr. at gene 5' and 3' Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
9	nsv533861	chr10:945438-1382068	Enhancers Weak transcription Strong transcription Active TSS Flanking Active TSS Genic enhancers Bivalent Enhancer ZNF genes & repeats Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
10	nsv530117	chr10:945438-1729634	Enhancers Weak transcription Flanking Active TSS ZNF genes & repeats Bivalent Enhancer Transcr. at gene 5' and 3' Active TSS Strong transcription Genic enhancers Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	38 gene(s)	inside rSNPs	diseases
11	nsv540408	chr10:955835-1260680	Enhancers Transcr. at gene 5' and 3' Strong transcription ZNF genes & repeats Genic enhancers Active TSS Weak transcription Flanking Active TSS Bivalent Enhancer Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	34 gene(s)	inside rSNPs	diseases
12	nsv817532	chr10:964660-1885945	Bivalent/Poised TSS Enhancers Strong transcription Flanking Active TSS Active TSS Weak transcription Bivalent Enhancer Genic enhancers Flanking Bivalent TSS/Enh ZNF genes & repeats Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	39 gene(s)	inside rSNPs	diseases
13	esv2753756	chr10:985264-1052950	Enhancers Strong transcription ZNF genes & repeats Flanking Active TSS Genic enhancers Active TSS Weak transcription Transcr. at gene 5' and 3' Bivalent Enhancer Flanking Bivalent TSS/Enh Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA	12 gene(s)	inside rSNPs	diseases
14	nsv1050577	chr10:986723-1277854	Weak transcription Strong transcription Transcr. at gene 5' and 3' ZNF genes & repeats Flanking Active TSS Enhancers Genic enhancers Bivalent/Poised TSS Active TSS Bivalent Enhancer Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	30 gene(s)	inside rSNPs	diseases
15	nsv540409	chr10:986723-1277854	Weak transcription Strong transcription Enhancers ZNF genes & repeats Flanking Active TSS Genic enhancers Bivalent Enhancer Active TSS Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	30 gene(s)	inside rSNPs	diseases
16	nsv949405	chr10:1010464-1376105	Weak transcription Active TSS Bivalent/Poised TSS Strong transcription Flanking Active TSS Enhancers Genic enhancers Bivalent Enhancer Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' ZNF genes & repeats	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	30 gene(s)	inside rSNPs	diseases
17	nsv1048254	chr10:1016006-1146595	Weak transcription Enhancers Strong transcription Flanking Active TSS Genic enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Active TSS ZNF genes & repeats Bivalent Enhancer Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region lncRNA miRNA target site	26 gene(s)	inside rSNPs	diseases
18	esv1812809	chr10:1021156-1051728	Weak transcription Enhancers Active TSS Strong transcription Flanking Active TSS ZNF genes & repeats Genic enhancers Bivalent/Poised TSS Transcr. at gene 5' and 3' Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region	11 gene(s)	inside rSNPs	diseases
19	esv1813158	chr10:1021156-1062915	Weak transcription Active TSS Strong transcription Flanking Active TSS ZNF genes & repeats Genic enhancers Enhancers Flanking Bivalent TSS/Enh Transcr. at gene 5' and 3' Bivalent/Poised TSS	TF binding region CpG island Chromatin interactive region	13 gene(s)	inside rSNPs	diseases
20	esv1831483	chr10:1021156-1062915	Active TSS Strong transcription Flanking Active TSS Weak transcription Enhancers ZNF genes & repeats Genic enhancers Transcr. at gene 5' and 3' Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region	13 gene(s)	inside rSNPs	diseases
21	nsv1040178	chr10:1024910-1126104	Strong transcription Active TSS Flanking Active TSS Enhancers Genic enhancers Weak transcription Transcr. at gene 5' and 3' ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases
22	nsv540410	chr10:1024910-1126104	Enhancers Genic enhancers Transcr. at gene 5' and 3' Flanking Active TSS Weak transcription Strong transcription Active TSS ZNF genes & repeats Bivalent/Poised TSS Flanking Bivalent TSS/Enh	TF binding region CpG island Chromatin interactive region lncRNA	26 gene(s)	inside rSNPs	diseases

mRNA abundance (count:1)

SNP	Gene	Cis/trans	Tissue	Source
rs7094916	WDR37	cis	parietal	SCAN

Chromatin state (count:127 , 50 per page) page: 1 2 3

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr10:1035000-1037200	Enhancers	Small Intestine	intestine
2	chr10:1035000-1038800	Weak transcription	Aorta	Aorta
3	chr10:1035000-1094000	Weak transcription	ES-WA7 Cell Line	embryonic stem cell
4	chr10:1035200-1037200	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
5	chr10:1035400-1039000	Weak transcription	H1 Derived Neuronal Progenitor Cultured Cells	ES cell derived
6	chr10:1035400-1040000	Weak transcription	Primary neutrophils fromperipheralblood	blood
7	chr10:1035400-1040400	Weak transcription	Brain Dorsolateral Prefrontal Cortex	brain
8	chr10:1035600-1037400	Enhancers	Primary T helper cells fromperipheralblood	blood
9	chr10:1035600-1037400	Enhancers	Primary T killer naive cells fromperipheralblood	blood
10	chr10:1035600-1038400	Weak transcription	Primary T cells effector/memory enriched fromperipheralblood	blood
11	chr10:1035600-1038800	Weak transcription	Primary mononuclear cells fromperipheralblood	Blood
12	chr10:1035600-1039000	Weak transcription	Fetal Kidney	kidney
13	chr10:1035600-1043600	Weak transcription	Pancreatic Islets	Pancreatic Islet
14	chr10:1035800-1037200	Genic enhancers	Osteobl	bone
15	chr10:1035800-1038600	Weak transcription	Brain Angular Gyrus	brain
16	chr10:1035800-1038600	Weak transcription	Fetal Muscle Trunk	muscle
17	chr10:1035800-1038600	Weak transcription	NHLF	lung
18	chr10:1035800-1038800	Weak transcription	ES-I3 Cell Line	embryonic stem cell
19	chr10:1035800-1038800	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
20	chr10:1035800-1038800	Weak transcription	Cortex derived primary cultured neurospheres	brain
21	chr10:1035800-1038800	Weak transcription	Brain Substantia Nigra	brain
22	chr10:1035800-1038800	Weak transcription	HSMMtube	muscle
23	chr10:1035800-1046800	Weak transcription	H1 BMP4 Derived Mesendoderm Cultured Cells	ES cell derived
24	chr10:1035800-1066200	Strong transcription	NH-A	brain
25	chr10:1036000-1037200	Genic enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
26	chr10:1036000-1037200	Enhancers	Primary T helper naive cells from peripheral blood	blood
27	chr10:1036000-1037400	Strong transcription	HUES6 Cell Line	embryonic stem cell
28	chr10:1036000-1037400	Genic enhancers	IMR90 fetal lung fibroblasts Cell Line	lung
29	chr10:1036000-1037400	Genic enhancers	Primary hematopoietic stem cells short term culture	blood
30	chr10:1036000-1037400	Genic enhancers	Primary T helper 17 cells PMA-I stimulated	--
31	chr10:1036000-1037400	Enhancers	Liver	Liver
32	chr10:1036000-1037400	Strong transcription	HSMM	muscle
33	chr10:1036000-1038400	Weak transcription	iPS-18 Cell Line	embryonic stem cell
34	chr10:1036000-1038400	Weak transcription	Primary monocytes fromperipheralblood	blood
35	chr10:1036000-1038400	Weak transcription	Primary T cells from cord blood	blood
36	chr10:1036000-1038400	Weak transcription	Adipose Nuclei	Adipose
37	chr10:1036000-1038400	Weak transcription	Brain Cingulate Gyrus	brain
38	chr10:1036000-1038400	Weak transcription	Brain Germinal Matrix	brain
39	chr10:1036000-1038400	Weak transcription	Placenta	Placenta
40	chr10:1036000-1038400	Weak transcription	Stomach Smooth Muscle	stomach
41	chr10:1036000-1038600	Weak transcription	Brain Inferior Temporal Lobe	brain
42	chr10:1036000-1038600	Weak transcription	Fetal Thymus	thymus
43	chr10:1036000-1038600	Weak transcription	NHDF-Ad	bronchial
44	chr10:1036000-1038800	Weak transcription	H9 Cell Line	embryonic stem cell
45	chr10:1036000-1038800	Weak transcription	Brain Anterior Caudate	brain
46	chr10:1036000-1038800	Weak transcription	Brain Hippocampus Middle	brain
47	chr10:1036000-1038800	Weak transcription	Colonic Mucosa	Colon
48	chr10:1036000-1038800	Weak transcription	Esophagus	oesophagus
49	chr10:1036000-1038800	Weak transcription	Fetal Brain Male	brain
50	chr10:1036000-1038800	Weak transcription	Fetal Intestine Large	intestine

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