Variant report

Variant	rs7158977
Chromosome Location	chr14:105950221-105950222
allele	C/T
Outlinks	Ensembl UCSC

Chromatin state
Related regulatory elements
Target genes
Other information

No.	Transcrition factor	Chromosome Location	Cell Line	Cell type	Cell Stage	Matched TF binding sites
1	POLR2A	chr14:105950189-105952553	HepG2	liver:	n/a	n/a
2	POLR2A	chr14:105949329-105950431	MCF-7	breast:	n/a	n/a
3	MAX	chr14:105949499-105950327	MCF-7	breast:	n/a	chr14:105949871-105949881
4	ELF1	chr14:105946015-105950277	MCF-7	breast:	n/a	n/a
5	ZBTB7A	chr14:105944229-105950591	ECC-1	luminal epithelium:	n/a	chr14:105944382-105944391
6	POLR2A	chr14:105949513-105950752	ECC-1	luminal epithelium:	n/a	n/a
7	EP300	chr14:105945971-105950322	ECC-1	luminal epithelium:	n/a	chr14:105949647-105949663 chr14:105948049-105948058
8	ZBTB7A	chr14:105945602-105950346	ECC-1	luminal epithelium:	n/a	n/a
9	POLR2A	chr14:105945578-105951699	ECC-1	luminal epithelium:	n/a	n/a
10	CHD2	chr14:105950153-105950291	HepG2	liver:	n/a	n/a
11	POLR2A	chr14:105949658-105950291	MCF-7	breast:	n/a	n/a

No.	Distal block	Cell Line	Cell type
1	chr14:105883580..105888149-chr14:105947638..105952467,6	MCF-7	breast:
2	chr14:105945980..105950779-chr14:105991667..105994836,5	K562	blood:
3	chr14:105862539..105866268-chr14:105946890..105950237,5	MCF-7	breast:
4	chr12:46659494..46662486-chr14:105949390..105951277,2	MCF-7	breast:
5	chr14:105902283..105908432-chr14:105944817..105951373,9	MCF-7	breast:

Variant related genes	Relation type
CRIP1	TF binding region
ENSG00000257341	TF binding region
ENSG00000111371	Chromatin interaction
ENSG00000182979	Chromatin interaction
ENSG00000251602	Chromatin interaction
ENSG00000226174	Chromatin interaction
ENSG00000184986	Chromatin interaction

Extended variants
information (count: 20 )
Associated
traits (count: 0)

rSNPs within LD-proxies of this variant (count:19)

rs_ID	r²[population]
rs10135326	0.85[AMR][1000 genomes]
rs10138891	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs10782498	0.81[AFR][1000 genomes]
rs11160845	0.99[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs12323571	0.95[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs13707	0.93[AMR][1000 genomes]
rs4983412	0.93[AMR][1000 genomes]
rs4983414	0.93[AMR][1000 genomes]
rs4983418	0.93[AMR][1000 genomes]
rs4983419	0.93[AMR][1000 genomes]
rs4983422	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs4983423	0.98[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs7140395	0.92[AFR][1000 genomes];1.00[AMR][1000 genomes]
rs7160858	0.82[AMR][1000 genomes]
rs73362069	1.00[AMR][1000 genomes]
rs7492892	0.93[AMR][1000 genomes]
rs7493450	0.93[AMR][1000 genomes]
rs8005552	0.86[AMR][1000 genomes]
rs8012089	0.94[AFR][1000 genomes];1.00[AMR][1000 genomes]

Variant overlapped rSNPs/rCNVs (count:1 , 50 per page) page: 1

No.	Variant name	Chromosome position	Chromatin state	Related regulatory elements	Target genes	Extended variants	Associated traits
1	nsv530813	chr14:105607701-106453697	Strong transcription Weak transcription Active TSS Bivalent Enhancer ZNF genes & repeats Genic enhancers Flanking Active TSS Enhancers Flanking Bivalent TSS/Enh Bivalent/Poised TSS Transcr. at gene 5' and 3'	TF binding region CpG island Chromatin interactive region lncRNA miRNA miRNA target site	149 gene(s)	inside rSNPs	diseases

No data

Chromatin state (count:92 , 50 per page) page: 1 2

No.	Chromosome Location	Chromatin state	Cell line	Tissue
1	chr14:105946600-105951200	Enhancers	H1 BMP4 Derived Trophoblast Cultured Cells	ES cell derived
2	chr14:105946800-105955200	Enhancers	H9 Derived Neuronal Progenitor Cultured Cells	ES cell derived
3	chr14:105947000-105951200	Enhancers	Breast variant Human Mammary Epithelial Cells (vHMEC)	Breast
4	chr14:105947000-105952400	Enhancers	hESC Derived CD56+ Mesoderm Cultured Cells	ES cell derived
5	chr14:105947000-105955200	Enhancers	H9 Derived Neuron Cultured Cells	ES cell derived
6	chr14:105947200-105953400	Enhancers	Placenta Amnion	Placenta Amnion
7	chr14:105947400-105953600	Enhancers	Lung	lung
8	chr14:105947600-105950600	Enhancers	Small Intestine	intestine
9	chr14:105948000-105950400	Enhancers	H1 Derived Mesenchymal Stem Cells	ES cell derived
10	chr14:105948000-105951000	Enhancers	HMEC	breast
11	chr14:105948000-105951200	Enhancers	Fetal Lung	lung
12	chr14:105948000-105951400	Enhancers	Sigmoid Colon	Sigmoid Colon
13	chr14:105948000-105951600	Enhancers	HSMM	muscle
14	chr14:105948000-105952400	Enhancers	Cortex derived primary cultured neurospheres	brain
15	chr14:105948000-105952600	Enhancers	Primary B cells from peripheral blood	blood
16	chr14:105948000-105952800	Enhancers	Primary T helper memory cells from peripheral blood 1	blood
17	chr14:105948000-105953000	Enhancers	Primary T killer memory cells from peripheral blood	blood
18	chr14:105948000-105953000	Bivalent Enhancer	Fetal Thymus	thymus
19	chr14:105948000-105953200	Enhancers	Left Ventricle	heart
20	chr14:105948000-105953200	Enhancers	Right Ventricle	heart
21	chr14:105948000-105953400	Enhancers	Esophagus	oesophagus
22	chr14:105948000-105954200	Enhancers	Fetal Heart	heart
23	chr14:105948000-105954400	Enhancers	Spleen	Spleen
24	chr14:105948200-105952800	Enhancers	Right Atrium	heart
25	chr14:105948400-105951400	Enhancers	Fetal Intestine Large	intestine
26	chr14:105948400-105952400	Enhancers	Primary Natural Killer cells fromperipheralblood	blood
27	chr14:105948400-105952400	Enhancers	Fetal Intestine Small	intestine
28	chr14:105948400-105953000	Enhancers	Breast Myoepithelial Primary Cells	Breast
29	chr14:105948400-105953200	Bivalent Enhancer	Fetal Stomach	stomach
30	chr14:105948400-105953600	Enhancers	Primary B cells from cord blood	blood
31	chr14:105948600-105952600	Bivalent Enhancer	Fetal Adrenal Gland	Adrenal Gland
32	chr14:105948600-105952800	Bivalent Enhancer	Fetal Muscle Trunk	muscle
33	chr14:105948800-105950400	Weak transcription	ES-UCSF4 Cell Line	embryonic stem cell
34	chr14:105948800-105950400	Enhancers	NHEK	skin
35	chr14:105948800-105950600	Enhancers	Foreskin Keratinocyte Primary Cells skin03	Skin
36	chr14:105948800-105950600	Enhancers	Gastric	stomach
37	chr14:105948800-105950600	Enhancers	HSMMtube	muscle
38	chr14:105948800-105951400	Enhancers	Fetal Muscle Leg	muscle
39	chr14:105948800-105951800	Enhancers	Placenta	Placenta
40	chr14:105948800-105952000	Weak transcription	iPS DF 6.9 Cell Line	embryonic stem cell
41	chr14:105948800-105952200	Enhancers	Colon Smooth Muscle	Colon
42	chr14:105948800-105952400	Enhancers	Primary T helper 17 cells PMA-I stimulated	--
43	chr14:105948800-105952400	Enhancers	Duodenum Mucosa	Duodenum
44	chr14:105948800-105952400	Enhancers	Rectal Mucosa Donor 29	rectum
45	chr14:105948800-105952600	Bivalent Enhancer	hESC Derived CD56+ Ectoderm Cultured Cells	ES cell derived
46	chr14:105948800-105952600	Enhancers	Primary T helper cells fromperipheralblood	blood
47	chr14:105948800-105952800	Bivalent Enhancer	Primary monocytes fromperipheralblood	blood
48	chr14:105948800-105952800	Enhancers	Primary T cells from cord blood	blood
49	chr14:105948800-105953000	Enhancers	Primary T helper cells PMA-I stimulated	--
50	chr14:105948800-105953200	Enhancers	Primary T killer naive cells fromperipheralblood	blood

The 2.0 version of rSNPBase

Variant report

Quick Search:

what's new

Quick links